Clinical trials: Morphine, completed
Pain, Postoperative
Methadone for Postoperative Pain
The aim of this study is to compare the efficacy of methadone versus morphine in dealing with postoperative pain, in laparoscopic cholecystectomy under total intravenous anesthesia (TIVA); Efficacy is defined in terms of the…
- Trial name
- NCT01833715
- Testing
- Morphine, Methadone, TIVA
- Where
- Chile
- Volunteers
- 86 people
- Sponsor
- Universidad de Valparaiso
Pain, Postoperative, Postoperative Complications
Methadone in Cystectomy Patients
The role of a single-dose intraoperative methadone on postoperative pain and opioid consumption in patients undergoing Surgeon Accuracy Robot Assistant cystectomy.
- Conditions
- Pain, Postoperative, Postoperative Complications, Pathologic Processes, Bladder Cancer
- Trial name
- METAMORF (NCT04475029)
- Testing
- Methadone, Morphine
- Where
- Denmark
- Volunteers
- 114 people
- Sponsor
- University of Aarhus
Multiple Trauma, Acute Pain Due to Trauma
Evaluation of Effect of Intravenous Morphine vs Intravenous Ibuprofen and Acetaminophen vs Intravenous Ibuprofen
Pain is an inseparable symptom of fractures and is the most important and common symptom that brings patients to medical centers; Therefore, paying attention to pain and its control is very important in the examination and…
- Trial name
- NCT05630222
- Testing
- Ibuprofen 800 mg, Morphine Sulfate, Ibuprofen 400 mg plus Acetaminophen 1000 mg
- Where
- Iran
- Volunteers
- 150 people
- Sponsor
- Isfahan University of Medical Sciences
Ketamine, Morphine
PCA Ketamine-Morphine VS PCA Morphine as Post-Operative Analgesia in Colorectal Surgery
The goal of this clinical trial is to compare the effectiveness of PCA ketamine-morphine versus conventional PCA morphine in postoperative patients undergoing elective laparotomy colorectal surgery under general anaesthesia.
- Trial name
- NCT06021717
- Testing
- Ketamine-Morphine, Morphine
- Where
- Malaysia
- Volunteers
- 60 people
- Sponsor
- Universiti Kebangsaan Malaysia Medical Centre
Anesthesia
Multimodal Opioid-free Anesthesia Versus Opioid-based Anesthesia for Patients Undergoing Cardiac Valve Surgeries: RCT
Several studies demonstrated the effectiveness of OFA in patients undergoing non-cardiac surgery. Preoperative use of Cox inhibitors, GABA analogues and acetaminophen have been shown to decrease use of opioids postoperatively .
- Trial name
- NCT04648540
- Testing
- Dexmedetomidine 0.5 mic/kg/h, Fentanyl 1 mic/kg/hr
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Anesthesia
Fentanyl Versus Morphine in Spinal Anesthesia for Caesarian Section - Study on Analgesia, Side Effects and Patient 's Satisfaction
Intrathecal morphine and fentanyl are used for anesthesia and perioperative pain management in caesarian section. Despite the fact that spinal Fentanyl is better tolerated, might not be enough for postoperative pain control.
- Trial name
- FvMinSA (NCT05533229)
- Testing
- Fentanyl, Morphine
- Where
- Romania
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Dr. Mihai Octavian Botea
Postoperative Pain
An Efficacy and Safety Study to Compare Morphine 6-glucuronide (M6G) and Morphine in Patients Suffering With Post-Operative Pain for at Least 24 Hours
To compare the incidence and severity of nausea in the study treatment groups, during the 18-hour period starting 6 hours after titration to pain relief; following confirmation of the assumption of non-inferiority between the two…
- Trial name
- NCT01082471
- Testing
- Morphine 6-glucuronide, Morphine
- Where
- 7 sites in Czechia, France and 4 more
- Volunteers
- 517 people
- Sponsor
- Paion UK Ltd.
Ketamine, Morphine
PCA Ketamine-Morphine VS PCA Morphine as Post-Operative Analgesia in Colorectal Surgery.
The goal of this clinical trial is to compare the effectiveness of PCA ketamine-morphine versus conventional PCA morphine in postoperative patients undergoing elective laparotomy colorectal surgery under general anaesthesia.
- Trial name
- NCT06010056
- Testing
- Ketamine-Morphine, Morphine
- Where
- Malaysia
- Volunteers
- 60 people
- Sponsor
- National University of Malaysia
Analgesia
Efficiency and Safety a Fixed Combination of Orphenadrine and Diclofenac for Postoperative Analgesia
The study will include 60 patients after cardiac surgery. The first group will include 30 patients who will use the drug Neodolpasse manufactured by Fresenius Kabi, which is a fixed combination of 30 mg of orphenadrine and 75 mg…
- Trial name
- NCT05322603
- Testing
- Analgesics Non Opioid (Neodolpasse manufactured by Fresenius Kabi), Analgesics
- Where
- Russia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Petrovsky National Research Centre of Surgery
Delirium
Dexmedetomidine Versus Morphine and Midazolam in Prevention and Treatment of Delirium After Adult Cardiac Surgery
This randomized double-blind parallel clinical study was conducted on 60 patients undergoing elective cardiac surgery under general anesthesia, at least 60 yr old, ASA I and II, 70-100 kg body weight and height 160-180 cm.
- Trial name
- NCT03078946
- Testing
- Dexmedetomidine Hydrochloride, Morphine and Midazolam
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Obesity, Analgesia
External Oblique Intercostal Plane Block for Laparoscopic Sleeve Gastrectomy
The external oblique intercostal (EOI) plane block is a novel approach upper abdominal wall analgesia. The EOI plane block can provide dermatomal sensory blockade of T6-T10 at the anterior axillary line and T6-T9 at the midline.
- Conditions
- Obesity, Analgesia, Postoperative Pain
- Trial name
- NCT05663658
- Testing
- Intravenous morphine patient control device, External oblique intercostal plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istinye University
Neonatal Abstinence Syndrome
Morphine Versus Methadone for Opiate Exposed Infants With Neonatal Abstinence Syndrome
This study investigates the use of methadone versus morphine wean for the treatment of neonatal abstinence syndrome for infants exposed to opioids in utero.
- Trial name
- NCT02851303
- Testing
- Morphine, Methadone
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- University of New Mexico
Postoperative Pain
Ultrasound Guided ESP Block Versus Intrathecal Morphine for Postoperative Analgesia in Major HPB Surgery.
To compare the efficacy of USG-guided bilateral Erector spinae plane block (ESPB) with intrathecal morphine (ITM) for postoperative analgesia after major hepatopancreaticobiliary surgery (HPB)
- Trial name
- NCT04635644
- Testing
- Erector Spinae Plane Block, Intrathecal morphine
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Assiut University
Analgesia, Congenital Heart Disease
Morphine IV vs Paracetamol IV in Neonates and Infants After Cardiac Surgery
The goal of this clinical trial is to compare pain management in neonates and infants under 3 years of age undergoing cardiac surgery with use of cardiopulmonary bypass.
- Conditions
- Analgesia, Congenital Heart Disease, Surgery
- Trial name
- PACS (NCT05853263)
- Testing
- paracetamol, Morphine
- Volunteers
- 208 people
- Sponsor
- Erasmus Medical Center
Analgesia Post Craniotomy
Opioid-Sparing Multimodal Analgesia Versus Opioid Analgesia for Postoperative Pain After Elective Craniotomy
Several neurosurgical procedures can cause postoperative pain including craniotomies for tumor resections, epilepsy surgery and craniotomies for aneurysm clipping, penetrating traumatic brain injury, and neuroradiological…
- Trial name
- NCT05474040
- Testing
- Morphine versus multimodal analgesia for post elective craniotomy pain
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Zagazig University
Pain, Postoperative, Pruritus
Postoperative Pain After Caesarian Section
To examine if perioperative pain/nausea/pruritus is altered when current standard analgesia for caesarian section (CS) is replaced with new guideline recommended analgesia.
- Conditions
- Pain, Postoperative, Pruritus, Nausea and Vomiting Following Administration of Anaesthetic Agent, Consumption
- Trial name
- NCT05659823
- Testing
- Bupivacaine-fentanyl-morphine elective group, Bupivacaine-fentanyl elective group, Bupivacaine-fentanyl emergency group
- Where
- Norway
- Volunteers
- 108 people
- Sponsor
- Conrad Arnfinn Bjørshol
Anesthesia; Adverse Effect, Cesarean Section Complications
Factors Associated With Failed Spinal Anesthesia for Cesarean Delivery
The aim of this study is to reveal the factor associated with failed spinal anaesthesia in cesarean delivery. We conduct the retrospective case-control study to elucidate the involving factors.
- Trial name
- NCT04685980
- Testing
- spinal anaesthesia with local anaesthetic and intrathecal morphine
- Where
- Thailand
- Volunteers
- 440 people
- Sponsor
- Mahidol University
Pain, Postoperative, Postoperative Complications
Analgesic Effect of Morphine Added to Transverses Abdominis Plane Block
Postoperative pain is a condition that increases morbidity and mortality. Therefore, multimodal analgesia techniques with fascial plan blocks are frequently used.TAP block provides analgesia in the anterior abdominal wall by…
- Trial name
- NCT05420337
- Testing
- Group ıntramuscular, Group TAP
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Eskisehir Osmangazi University
Postoperative Pain
Spinal Hydromorphone Versus Morphine for Post-Cesarean Delivery Analgesia
Morphine is usually used for pain relief after cesarean delivery. However, sometimes it is not available, the patient might be allergic to morphine or intolerant to its side effects.
- Trial name
- NCT03592992
- Testing
- Spinal Hydromorphone, Spinal Morphine
- Where
- Canada
- Volunteers
- 126 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Postoperative Pain
Morphine Added to Ropivacaine for FICB for Postoperative Analgesia
prospective, randomized double blinded study to investigate the effects of morphine as an adjuvant to ropivacaine on FICB
- Trial name
- NCT03875274
- Testing
- Ropivacaine, Morphine, Ropivacaine, Saline
- Where
- Nepal
- Volunteers
- 70 people
- Sponsor
- B.P. Koirala Institute of Health Sciences