Clinical trials: Oxycodone, completed
Pain Management
Analgesic Efficacy of (MSIR)/Acetaminophen vs. Oxycodone/Acetaminophen (Percocet)
Oxycodone and Hydrocodone are the most commonly used oral opioid analgesics in the emergency department and in outpatient settings.
- Trial name
- NCT03088826
- Testing
- Morphine Sulfate, Oxycodone, Acetaminophen
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Antonios Likourezos
Hip Arthroplasty, Knee Arthroplasty
Effect of Combined Use of Naloxone and Tramacet on Postop Analgesia in Elderly Patients Having Joint Replacement Surgery
Patients over 70 years of age, scheduled for joint replacement surgery will be randomized to tramacet/ naloxone plus morphine PCA or to morphine PCA to assess quality of analgesia in the postoperative period.
- Conditions
- Hip Arthroplasty, Knee Arthroplasty, Spinal Anesthesia
- Trial name
- NCT00679614
- Testing
- tramacet, naloxone, tramacet, Acetaminophen
- Where
- Canada
- Volunteers
- 45 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Breast Cancer, Pain, Acute
ESP in Breast Surgery Due to Cancer
Patients scheduled for breast surgery due to cancer. Each patient will be treated with intravenous (i.v.) oxycodone - patient-controlled analgesia (PCA).
- Conditions
- Breast Cancer, Pain, Acute, Anesthesia, Local
- Trial name
- NCT04726878
- Testing
- Erector spinae plane block, General anesthesia, Patient-controlled analgesia
- Where
- Poland
- Volunteers
- 75 people
- Sponsor
- Medical University of Lublin
Thyroid Disease, Parathyroid Diseases
Pain Medications Following Thyroidectomy and Parathyroidectomy
The purpose of this study is to evaluate the use of a non-narcotic, postoperative pain management regimen on patients undergoing thyroidectomy and parathyroidectomy.
- Trial name
- NCT03640247
- Testing
- Non-narcotic group regimen, Narcotic group regimen
- Where
- United States
- Volunteers
- 126 people
- Sponsor
- MetroHealth Medical Center
Pain
Oxycodone-naloxone in Relieving Opioid-related Constipation
The primary objective of this study is to demonstrate that subjects with moderate to severe non-malignant pain taking oxycodone/naloxone prolonged release tablets have improvement in symptoms of constipation compared to subjects…
- Trial name
- NCT00412152
- Testing
- Oxycodone nalaxone prolonged release tablets (OXN)
- Sponsor
- Mundipharma Research GmbH & Co KG
Carpal Tunnel Syndrome, Dupuytren Contracture
Ibuprofen Plus Acetaminophen Versus Oxycodone Alone After Hand Surgery
This study is about pain control and medication following outpatient soft-tissue hand surgery. We hope to learn if ibuprofen and acetaminophen will achieve similar pain relief and satisfaction when compared with oxycodone alone.
- Conditions
- Carpal Tunnel Syndrome, Dupuytren Contracture, Trigger Digit, Ganglion Cysts
- Trial name
- NCT03111186
- Testing
- Oxycodone Hcl 5Mg, Ibuprofen 400 mg, Acetaminophen 650 mg
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Southern California
Postcraniotomy Pain
Comparison of the Efficacy of Oral Oxycodone and Oral Codeine in the Treatment of Postcraniotomy Pain
The efficacy of codeine is dependent on its demethylation to morphine. This extent of demethylation has wide inter-individual variability, making codeine's efficacy as a analgesic variable.
- Trial name
- NCT01672112
- Testing
- Oxycodone, Codeine
- Where
- Singapore
- Volunteers
- 40 people
- Sponsor
- Tan Tock Seng Hospital
Chronic Noncancer Pain
Safety Study of Oxycodone Hydrochloride and Naltrexone Hydrochloride Extended-Release Capsules in Subjects With Moderate to Severe Chronic Noncancer Pain
The study will provide information to assess the benefits versus risks of extended exposure to oxycodone HCl and naltrexone HCl extended-release capsules in a chronic noncancer pain population.
- Trial name
- NCT01428583
- Testing
- oxycodone HCl and naltrexone HCl extended-release capsules
- Where
- 32 sites in United States
- Volunteers
- 395 people
- Sponsor
- Pfizer
Cancer, Pain
Determine the Safety and Efficacy of Oxy/Nal Tablets Compared to Oxy PR in Subjects With Cancer Pain
To Determine the Safety and Efficacy of Oxycodone / Naloxone Prolonged Release Tablets compared to Oxycodone PR in Subjects with Moderate to Severe, Chronic Cancer Pain
- Trial name
- NCT01885182
- Testing
- Oxycodone/Naloxone, Oxycodone
- Where
- 28 sites in China
- Volunteers
- 232 people
- Sponsor
- Mundipharma (China) Pharmaceutical Co. Ltd
Pregnancy Related, Opioid Use
Opioid Prescription After Cesarean Trial
Non-inferiority randomized trial of 5,500 women with a cesarean delivery randomized prior to discharge to either an individualized opioid prescription protocol (IOPP) that includes shared decision making or to a fixed opioid…
- Conditions
- Pregnancy Related, Opioid Use, Pain
- Trial name
- PACT (NCT04296396)
- Testing
- 0 to 20 tablets of oxycodone 5mg, Fixed opioid prescription
- Where
- 12 sites in United States
- Volunteers
- 5,521 people
- Sponsor
- The George Washington University Biostatistics Center
Pain, Postoperative, Pain Uterus
Effects of Tapentadol Versus Oxycodone After Hysterectomy.
Opioids remain the first-line drugs for the treatment of moderate to severe postoperative pain, but the use is limited by well-known side-effects, most of which are dose-dependent.
- Conditions
- Pain, Postoperative, Pain Uterus, Pain, Acute, Opioid Use
- Trial name
- NCT03314792
- Testing
- Tapentadol, Oxycodone
- Where
- Norway
- Volunteers
- 86 people
- Sponsor
- Oslo University Hospital
Healthy
A Randomized, Two-way, Crossover Study to Estimate the Relative Bioavailability of a Controlled-release Formulation of Oxycodone (40 mg) With Sequestered Naltrexone Compared With Immediate-release Oxycodone Tablets (20 mg) in Healthy Volunteers
To determine whether the bioavailability of the controlled-release test formulation is at least as high as that for the commercial reference drug.
- Trial name
- NCT01677065
- Testing
- Oxycodone controlled-release test formulation, Immediate-release reference drug
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Pfizer
Osteo Arthritis Knee
The Effect of Prolonged Multimodal Analgesic Regimen on Post Hospital Discharge Opioid Use and Pain Control After Primary Total Knee Arthroplasty
It is well recognized that a multimodal analgesia program targeting multiple pain pathways, is more effective for controlling pain during the hospital stay and in the acute postoperative period than monotherapy-based regimens…
- Trial name
- NCT04003350
- Testing
- Oxycodone, Tramadol, Tylenol
- Where
- United States
- Volunteers
- 216 people
- Sponsor
- Rothman Institute Orthopaedics
Cancer Pain, Neoplasms
GREAT - Good Response With Appropriate Treatment
The symptoms associated in advanced cancer patients and adverse events due to use of opioids have major influence on the state of health and quality of life of patients.
- Trial name
- NCT02293785
- Testing
- Oxycodone-Naloxone
- Where
- 18 sites in Italy
- Volunteers
- 200 people
- Sponsor
- Mario Negri Institute for Pharmacological Research
Pain, Intractable
Phase II Clinical Trial of Fentanyl Transdermal Matrix Patch, in the Management of Cancer Pain- Assessment of Effectiveness, Safety and Pharmacokinetics -
The purpose of this study is to verify the effectiveness, safety and pharmacokinetics of fentanyl transdermal matrix patches containing either 12.5 mcg/hr, 25 mcg/hr, or 50 mcg/hr in Japanese patients with cancer pain who have…
- Trial name
- NCT00216658
- Testing
- fentanyl
- Volunteers
- 87 people
- Sponsor
- Janssen Pharmaceutical K.K.
Cesarean Section Complications, Opioid Use
Precision Opioid Care After Cesarean Delivery (PRECISE-CD)
The purpose of this research is to study serious clinical problems from surgical pain and the use of oxycodone or other opioids in women having a Cesarean Delivery to improve the safety and efficacy of surgical pain relief.
- Trial name
- PRECISE-CD (NCT05280743)
- Testing
- Oxycodone
- Where
- United States
- Volunteers
- 341 people
- Sponsor
- Grace Lim, MD, MS
Post Operative Pain
OXN PR Compared to OXY PR in Subjects With Postoperative Pain After Knee Arthroplasty
The purpose of this study is to demonstrate that treatment with OXN PR tablets is non inferior to treatment with OXY PR tablets in terms of analgesic efficacy in patients with postoperative pain after knee arthroplasty based on…
- Trial name
- OXN4505 (NCT01083485)
- Testing
- Oxycodone/Naloxone PR 20/10mg or 10/5mg tablets, Oxycodone
- Where
- Finland
- Volunteers
- 137 people
- Sponsor
- Mundipharma Oy
Hip Arthroscopy
Nonopioid Pain Control Regimen After Arthroscopic Hip Procedures
This study is being conducted to evaluate the effectiveness of post-operative pain control without using narcotic pain medications.
- Trial name
- NCT05076110
- Testing
- Oxycodone, Ibuprofen, Gabapentin
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- Mayo Clinic
ACL Tear, Post Operative Pain
Impact of Opioid Avoidance Protocol for ACL Reconstruction
This is a prospective, quasi-experimental, cohort study comparing patients treated with one of two postoperative pain management protocols.
- Trial name
- NCT06340932
- Testing
- Iovera, Celecoxib, Acetaminophen
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Matthew Varacallo
Cancer, Pain
A Study to Compare the Titration Efficacy and Safety of Control-released Oxycodone and Immediate-released Oxycodone in Patients With Moderate to Severe Cancer Pain
This study is to evaluate the efficacy and safety of a titration method by selects 10 mg control-released (CR) oxycodone tablet as background drug in combined with immediate-released (IR) oxycodone, compared to conventional…
- Trial name
- NCT03176199
- Testing
- Oxycodone
- Where
- 4 sites in Taiwan
- Volunteers
- 30 people
- Sponsor
- Taiwan Mundipharma Pharmaceuticals Ltd.