Clinical trials: Oxycodone, completed
Pain, Post-operative, Third Molar
Controlled Trial to Determine Most Effective Post-Operative Analgesia After Third Molar Extraction
This is a prospective randomized clinical trial that will investigate which post-operative medications in conjunction with a multimodal analgesia approach can most effectively control post-operative pain and reduce opioid…
- Conditions
- Pain, Post-operative, Third Molar, Oral Surgery, Pain, Acute
- Trial name
- NCT06484439
- Testing
- Ketorolac, Oxycodone, Acetaminophen
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- United States Naval Medical Center, San Diego
Upper Abdominal Malignancies, Upper Gastrointestinal Cancer
Comparison of CT-Guided Celiac Plexus Neurolysis and Pharmacotherapy
After enrolment, patients were randomly assigned to two groups by means of a lottery procedure, whereby each patient blindly chose one of two labelled slips, resulting in group assignment to receive.
- Trial name
- NCT07761650
- Testing
- CT-guided celiac plexus neurolysis, Standard pharmacotherapy
- Where
- Pakistan
- Volunteers
- 110 people
- Sponsor
- Mayo Hospital Lahore
Analgesia
Medico-economic Evaluation of Sublingual PCA (Zalviso) Versus Oxycodone-PCA in the Management of Postoperative Pain.
More than 230 million surgical operations are been realized all over the world every year. A surgical intervention can cause postoperative acute pain.
- Trial name
- MEZO (NCT03882320)
- Testing
- Patient Controlled Analgesia (PCA)
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Flank Pain, Urinary Bladder, Overactive
Therapeutic Merit of Solifenacin in the Mitigation of Ureteral Stent-induced Pain and Lower Urinary Tract Symptoms
Most ureteral stent insertions follow ureteroscopy procedures for stone management. Stents are essentially designed to prevent the blockage of the ureter.
- Trial name
- NCT01381120
- Testing
- Solifenacin succinate treatment, Oxycodone and acetaminophen combination treatment
- Where
- Canada
- Volunteers
- 84 people
- Sponsor
- Barrie Urology Associates
Postoperative Nausea and Vomiting, Colorectal Neoplasms
Acupuncture for Postoperative Nausea and Vomiting in Patients Undergoing Colorectal Surgery
Background: PONV is one of the prevalent discomforts in the early phase of recovery after surgery. Evidence suggests that the stimulation of the P6 acupuncture point can reduce the occurrence of PONV.
- Trial name
- AcuPONV (NCT02509143)
- Testing
- High-dose acupuncture with intravenous infusion of ramosetron, P6 stimulation with intravenous infusion of ramosetron, Intravenous infusion of ramosetron
- Where
- 2 sites in South Korea
- Volunteers
- 60 people
- Sponsor
- Pusan National University Yangsan Hospital
Anterior Cruciate Ligament Rupture
Are Opioids Needed After ACL Reconstruction
As the public health sector continues to confront the opioid epidemic, orthopaedic surgeons must revisit pain management protocols to reduce unnecessary opioid prescriptions.
- Trial name
- NCT04285853
- Testing
- Oxycodone
- Where
- 3 sites in United States
- Volunteers
- 98 people
- Sponsor
- Emory University
Opioid Prescribing
Postoperative Nudges to Reduce Opioid Prescribing
This study tests the effectiveness of two email-based behavioral nudges, one based on peer behavior and one based on best practice guidelines, in reducing excessive opioid prescriptions after surgery.
- Trial name
- POST-OP (NCT05070338)
- Testing
- Guideline-Based (Injunctive Norm) Nudges, Peer-Based (Social Norm) Nudges
- Where
- United States
- Volunteers
- 640 people
- Sponsor
- RAND
Healthy Volunteers
Single-Dose PK Study of an Oxycodone/Acetaminophen Solution in Healthy Subjects
A single-dose study evaluating the oral PK of an oxycodone/apap solution in healthy subjects under fasted conditions
- Trial name
- NCT02966860
- Testing
- Oral solution OC/APAP
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Mallinckrodt
Postoperative Pain, Opioid Dependence
PG and PK of Oxycodone to Personalize Post-op Pain Management Following Surgery in Children
Each year, in the U.S. alone, >6 million children undergo painful surgery; up to 50% of them experience significant and serious side effects with opioids and inadequate pain relief.
- Trial name
- NCT03495388
- Testing
- Oxycodone
- Where
- 2 sites in United States
- Volunteers
- 129 people
- Sponsor
- Senthil Sadhasivam
Pain
A Trial Assessing the Outcome of Celecoxib Administration Versus Placebo Following Anterior Cruciate Ligament (ACL) Reconstruction
The aim of this study is to directly compare the clinical outcomes of both the celecoxib and placebo groups following anterior cruciate ligament (ACL) reconstruction. The study will have short and long term goals.
- Trial name
- NCT01186887
- Testing
- Celecoxib
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Ottawa Hospital Research Institute
Pain, Opioid Induced Constipation
Non-interventional Study Comparing Targiniq and Oxycodone/Laxatives
The objective of the non-interventional study is to compare the quality of life, health care resource use and costs between the use of a combination of oxycodone and naloxone (Targiniq) versus oxycodone and laxatives for patients…
- Trial name
- NCT01812733
- Where
- Sweden
- Volunteers
- 37 people
- Sponsor
- Mundipharma AB
Postoperative Pain
OxyNorm Capsules in Post-Operative Pain Study
The efficacy and safety of oxycodone capsules compared with morphine tablets in hospitalized patients with moderate to severe pain following surgery.
- Trial name
- NCT01675635
- Testing
- OxyNorm Capsules, Morphine tablet
- Volunteers
- 240 people
- Sponsor
- Mundipharma (China) Pharmaceutical Co. Ltd
ACL Injury, Postoperative Pain
Ketorolac as an Adjuvant Agent for Postoperative Pain Control Following Arthroscopic ACL Surgery
1. The investigators aim to examine the use of IV and oral ketorolac as an adjunctive agent to the standard of care pain protocol for postoperative pain control following ACL reconstruction surgery. 2.
- Trial name
- NCT04246554
- Testing
- Ketorolac, Oxycodone-Acetaminophen
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Postoperative Pain
A Study of Two Approved Drugs in the Treatment of Postoperative Dental Pain (0966-183)
The purpose of this study is to compare the safety and effectiveness of two approved drugs in the treatment of pain following dental surgery.
- Trial name
- NCT00092326
- Testing
- MK0966, rofecoxib
- Volunteers
- 269 people
- Sponsor
- Merck Sharp & Dohme LLC
Surgery
Ambulatory Gynecologic Surgery: Finding the Optimal Opioid Prescription
Currently there is a nationwide epidemic in opioid abuse and overdose deaths. While the opioid epidemic is multi-factorial one major source of excess opioids may be over-prescribing in the post-operative period.
- Trial name
- NCT03588910
- Testing
- Acetaminophen, Ibuprofen 600 mg, Oxycodone
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Pain
Optimal Dose of i.v Oxycodone for Postoperative Pain
Postoperative pain control is required after major abdominal surgery, including laparoscopic colorectal surgery. Intravenous oxycodone is widely used for postoperative acute pain control mainly in Europe.
- Trial name
- NCT02732262
- Testing
- Oxycodone, 1.00 mg dose, Oxycodone, 0.03 mg/kg dose, Oxycodone, 0.02 mg/kg dose
- Where
- South Korea
- Volunteers
- 134 people
- Sponsor
- Seoul National University Hospital
MAB, Pain
Opioid Analgesia for MAB
Our primary objective will be to determine if a strong opioid, oxycodone, given at a dose recommended for severe pain in addition to ibuprofen decreases maximum pain scores compared to ibuprofen and placebo in women undergoing…
- Trial name
- NCT03139240
- Testing
- Oxycodone 10mg oral
- Where
- United States
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Post Operative Pain
Analgesic Efficacy of Saphenous Nerve Block in Total Knee Replacement
We hypothesize that preoperative saphenous nerve block (SNB) in combination with periarticular local infiltration provides better post operative pain relief (POPR) profile as compared to local infiltration alone
- Trial name
- NCT01991288
- Testing
- SNB Saphenous Nerve Block, NSNB Non Saphenous Nerve Block
- Where
- Ireland
- Volunteers
- 20 people
- Sponsor
- Cork University Hospital
Chronic Pain, Low Back Pain
A Research Study of an Investigational Drug ALO-02 (Oxycodone Hydrochloride and Naltrexone Hydrochloride) in Patients With Moderate to Severe Chronic Low Back Pain
The primary objective of the study is to determine the analgesic efficacy and safety of ALO-02 extended-release capsules, when compared to placebo, in subjects with moderate to severe chronic low back pain.
- Conditions
- Chronic Pain, Low Back Pain, Analgesia
- Trial name
- NCT01571362
- Testing
- ALO-02
- Where
- 52 sites in United States
- Volunteers
- 410 people
- Sponsor
- Pfizer
Cesarean Section Complications
Towards Enhanced Recovery After Cesarean
One in 300 women will become persistent opioid users after cesarean delivery (1). Cesarean delivery is the most common surgical procedure in the United States, representing 31.9% of the 3,788,235 deliveries in 2018 (2).
- Trial name
- ERAS (NCT04612920)
- Testing
- Ibuprofen, acetaminophen, oxycodone
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- University of Oklahoma