Clinical trials: Oxycodone
Morbid Obesity
Enhanced Recovery After Laparoscopic Sleeve Gastrectomy - a Randomised Controlled Trial
The investigators wish to standardise and optimise perioperative care for consecutive patients undergoing laparoscopic sleeve gastrectomy for weight loss.
- Trial name
- NCT01303809
- Testing
- Enhanced Recovery After Surgey for Sleeve Gastrectomy
- Where
- New Zealand
- Volunteers
- 106 people
- Sponsor
- University of Auckland, New Zealand
Postoperative Pain, Acute Pain
Suzetrigine Versus Standard Analgesia After Skin Cancer Surgery
This randomized clinical trial will compare suzetrigine with standard analgesia for postoperative pain management after skin cancer surgery.
- Conditions
- Postoperative Pain, Acute Pain, Skin Cancer, Cutaneous Malignancy
- Trial name
- NCT07843134
- Testing
- Suzetrigine, Acetaminophen Plus Ibuprofen
- Where
- 3 sites in United States
- Volunteers
- 230 people
- Sponsor
- University of Minnesota
Chronic Pain
Fentanyl Buccal Tablets Versus Immediate Release Oxycodone for Breakthrough Pain in Patients With Chronic Pain
Evaluate the efficacy of treatment with the fentanyl buccal tablet (FBT) compared with immediate release oxycodone treatment in alleviating breakthrough pain (BTP) in opioid tolerant patients with chronic pain.
- Trial name
- NCT00813488
- Testing
- Fentanyl Buccal Tablet, Immediate release oxycodone
- Where
- 50 sites in United States
- Volunteers
- 213 people
- Sponsor
- Cephalon
Pain, Postoperative
Pain Management After Surgery
Following outpatient orthopaedic surgery, adequate pain control is imperative both for patient satisfaction and for improved recovery and rehabilitation.
- Trial name
- NCT05154682
- Testing
- OxyCODONE 5 mg Oral Tablet, Acetaminophen 500Mg Tab, Naproxen 500 Mg
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Rothman Institute Orthopaedics
Healthy
A Open-label, Single-dose Study to Investigate The Pharmacokinetics Between a GL2907 XL and Oxycontin CR Tab. 10mg in Healthy Male Volunteers
The purpose of this clinical trial is to compare the pharmacokinetic characteristics of GL2907 XL 20mg tablet and Oxycontin CR 10mg tablet. GL2907 XL 20mg tablet is controlled released formulation which is made by GL Pharm Tech.
- Trial name
- GL2907-101 (NCT01568450)
- Testing
- Oxycodone
- Where
- South Korea
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- GL Pharm Tech Corporation
Healthy
Effects of Food on Oxycodone Pharmacokinetics in Healthy Volunteers
To estimate the effect of food on the pharmacokinetics and relative bioavailability of oxycodone following oral administration of single 40 mg doses of PF 00345439 Formulation K taken whole or after chewing in healthy volunteers.
- Trial name
- NCT02117583
- Testing
- Oxycodone
- Where
- 2 sites in United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Pain Therapeutics
Postoperative Pain
Efficacy and Safety of Q8003 in the Management of Post-bunionectomy Pain
This study will explore the efficacy and safety of a fixed dose combination of morphine and oxycodone for management of acute postoperative pain.
- Trial name
- NCT00560183
- Testing
- Q8003 (morphine sulfate and oxycodone hydrochloride)
- Where
- 6 sites in United States
- Volunteers
- 256 people
- Sponsor
- QRxPharma Inc.
Gastric Cancer
Multimodal Analgesia in Laparoscopic Radical Gastrectomy With Gastric Cancer: a Multi-center Study
The study is aimed to explore the effects of multimodal analgesia consisting of ropivacaine's wound infiltration, parecoxib's intravenous injection and oxycodone-acetaminophen tablets' oral administration on postoperative pain…
- Trial name
- NCT03236051
- Testing
- Multimodal analgesia, PCIA analgesia
- Where
- 2 sites in China
- Volunteers
- 156 people
- Sponsor
- JIANG Zhi-Wei
Pregnancy Related, Narcotic Use
Determining the Effect of an "Alternate Recovery Protocol" Versus Current Standard of Care After Cesarean Section
This randomized controlled trial will compare two different approaches to patient recovery after cesarean section: the current standard of care versus an alternate management protocol.
- Trial name
- NCT03330119
- Testing
- Alternate Management, Control
- Where
- United States
- Volunteers
- 1,494 people, healthy volunteers welcome
- Sponsor
- Brest, Norman A., M.D.
Cancer Pain, Real-world Study
Real World Study of Oxycodone Sustained-release Tablets for Patients With Moderate to Severe Cancer Pain
The goal of this real world study is to observe the efficacy and safety of Oxycodone Hydrochloride Sustained-release Tablets in the treatment of moderate to severe cancer pain participants in real clinical practice.
- Conditions
- Cancer Pain, Real-world Study, Oxycodone
- Trial name
- NCT05962294
- Where
- China
- Volunteers
- 916 people
- Sponsor
- Henan Cancer Hospital
Post-operative Pain Control
Post-operative Pain Control After Photorefractive Keratectomy Comparing Acetaminophen/Codeine vs Acetaminophen/Oxycodone
Photorefractive keratectomy (PRK) is a refractive error correction procedure that helps eliminate or reduce the dependence on corrective lenses. An important aspect of PRK is post-operative pain management.
- Trial name
- NCT04399122
- Testing
- acetaminophen/codeine vs acetaminophen/oxycodone
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- 59th Medical Wing
Healthy
Effects of Ethanol on Oxycodone Pharmacokinetics in Healthy Volunteers
To Estimate Bioavailability Of 40 Mg Doses Of Pf-00345439 Formulation K Under Fasting Conditions with 40% Ethanol Compared with Water in Healthy Volunteers
- Trial name
- NCT02165930
- Testing
- Oxycodone, Naltrexone
- Where
- 2 sites in United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Pain Therapeutics
Pain
Oxycodone-naloxone Prolonged Release Tablets in Relieving Opioid-related Constipation
The primary objective is to demonstrate that patients taking oxycodone/naloxone prolonged release tablets have improvement in symptoms of constipation compared to subjects taking oxycodone prolonged release tablets alone.
- Trial name
- NCT00412100
- Testing
- Oxycodone naloxone prolonged release tablets (OXN)
- Sponsor
- Mundipharma Research GmbH & Co KG
Osteoarthritis
Effects of Duloxetine on Pain Relief After Total Knee Arthroplasty in Central Sensitization Patient
This study aims to compare the effectiveness of duloxetine after total knee arthroplasty in Central sensitization patient. Central sensitization plays an important role in the chronic pain experienced by osteoarthritis…
- Trial name
- NCT02600247
- Testing
- Duloxetine, celecoxib, Pregabalin, acetaminophen/tramadol, oxycodone
- Volunteers
- 100 people
- Sponsor
- The Catholic University of Korea
Pain Control After Functional Endoscopic Sinus Surgery and Septoplasty
Are NSAIDs Effective Enough for Postoperative Pain Control After Functional Endoscopic Sinus Surgery and Septoplasty
The purpose of this study is to compare the level of pain control in patients receiving non-steroidal anti-inflammatory drugs (NSAIDs) to those receiving opioids in the postoperative period after endoscopic sinus surgery (ESS)…
- Trial name
- NCT03605914
- Testing
- diclofenac, Norco
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- The University of Texas Health Science Center, Houston
Carpal Tunnel
Narcotic vs. Non-narcotic Pain Study Protocol
The purposes of this noninferiority randomized clinical trial are to: 1. determine whether the most commonly used commonly used non-narcotic analgesic (ibuprofen 600 mg + acetaminophen 325 mg) provides pain relief that is not…
- Trial name
- NCT01974609
- Testing
- Narcotic, non-narcotic
- Where
- 7 sites in United States, Canada
- Volunteers
- 347 people
- Sponsor
- Horizon Health Network
Pain, Postoperative, Cardiac Surgery
Chest Wall Block After Sternotomy: Randomized Controlled Trial in Cardiac Surgery: (PABLOS Study)
The main objective is to compare the effectiveness of LocoRegional Anesthesia (LRA) (bilateral transverse thoracic block or bilateral parasternal block) in addition to standard management compared to standard management alone…
- Trial name
- PABLOS (NCT05345639)
- Testing
- LRA Loco-regional anesthesia, Standardized post-operative analgesia protocol
- Where
- France
- Volunteers
- 254 people
- Sponsor
- University Hospital, Angers
Metastatic Cancer
S1916 Digital Medicine Program for Pain Control in Cancer Patients
This is a feasibility study to assess the use of a Digital Medicine Program (consisting of an FDA-approved ingestible sensor co-encapsulated with oxycodone/acetaminophen (5 mg/325 mg), a small wearable patch, and a mobile…
- Trial name
- NCT04194528
- Testing
- Oxycodone/acetaminophen 5/325 mg, Proteus digital medicine program
- Where
- 5 sites in United States
- Volunteers
- 2 people
- Sponsor
- SWOG Cancer Research Network
Moderate-to-severe Chronic Low Back Pain
Efficacy and Safety of Egalet-002 in Patients With Moderate-to-Severe Chronic Low Back Pain
The purpose of this study is to determine the analgesic efficacy of Egalet-002 twice daily (BID) in patients with moderate-to-severe chronic low back pain
- Trial name
- NCT02716857
- Testing
- Oxycodone extended-release
- Where
- 74 sites in United States
- Volunteers
- 549 people
- Sponsor
- Egalet Ltd
Epidural, Oxycodone
Epidural Oxycodone for Pain Management for Lower Limb Amputation
The aim of this study is to evaluate the effect of epidural oxycodone for pain management after lower limb amputation.
- Conditions
- Epidural, Oxycodone, Pain, Lower Limb Amputation
- Trial name
- NCT06276179
- Testing
- Oxycodone, Bupivacaine
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Kafrelsheikh University