Clinical trials: Oxycodone
Constipation
Opioid Induced Bowel Dysfunction in Patients Undergoing Spinal Surgery
In the present study, the primary aim was to evaluate if oxycodone-naloxone combination compared to oxycodone reduced opioid induced constipation in patients with or without chronic opioid treatment undergoing spine surgery.
- Trial name
- oksineukir (NCT02573922)
- Testing
- oxycodone-naloxone, Oxycodone
- Where
- Finland
- Volunteers
- 180 people
- Sponsor
- Kuopio University Hospital
Osteoarthritis
Tanezumab In Osteoarthritis Of The Hip Or Knee
The purpose of the study is to test the efficacy and safety of 2 doses of tanezumab compared to oxycodone CR and placebo in patients with osteoarthritis
- Trial name
- NCT00985621
- Testing
- tanezumab 10 mg, tanezumab 5 mg, oxycodone
- Where
- 112 sites in United States, Austria and 5 more
- Volunteers
- 614 people
- Sponsor
- Pfizer
Postoperative Pain, Opioid Related Disorders
A Comparison of PR Oxycodone/Naloxone and PR Oxycodone After Cardiac Surgery
The aim of the study is to describe the effects of oxycodone/naloxone combination in comparison to oxycodone for the treatment of postoperative pain in patients undergoing cardiac surgery.
- Trial name
- NCT01374763
- Testing
- Oxycodone, Prolonged-release oxycodone/naloxone
- Where
- Finland
- Volunteers
- 165 people
- Sponsor
- Kati Järvelä
Pain, Postoperative
Opioid & Steroid Use Following Tonsillectomy in Pediatric Patients
The purpose of this study is to determine if a post-operative course of oral dexamethasone affects opioid usage in pediatric patients undergoing tonsillectomy.
- Trial name
- NCT04541147
- Testing
- Dexamethasone, Analgesics
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Duke University
Pain
Oxycodone/Naloxone (OXN) Combination in Moderate to Severe Non-malignant Pain
The main objective of the study is to evaluate the patient preference for pain treatment with respect to quality of life in patients with moderate to severe non malignant pain.
- Trial name
- NCT01167699
- Testing
- Oxycodone and naloxone
- Where
- Belgium
- Volunteers
- 174 people
- Sponsor
- Mundipharma Pharmaceuticals B.V.
Hospital Costs, Length of Stay
A Trial of the Cost Effectiveness of IV Acetaminophen in Bariatric Surgery
Bariatric surgery is the only proven and effective long term treatment for morbid obesity. In an attempt to reduce patients' post-operative hospital stay, lower associated health care costs, and improve satisfaction scores, St…
- Conditions
- Hospital Costs, Length of Stay, Postoperative Pain Score, Patient Satisfaction
- Trial name
- NCT02233400
- Testing
- Acetaminophen
- Where
- 2 sites in United States
- Volunteers
- 113 people
- Sponsor
- St. Luke's Hospital and Health Network, Pennsylvania
Dental Pain
Study of Buprenorphine HCl Buccal Film in the Treatment of Dental Pain
The purpose of this study is to assess the activity of buprenorphine hydrochloride (HCl) buccal film in the treatment of dental pain.
- Trial name
- NCT00941304
- Testing
- Oxycodone, Buprenorphine
- Where
- 3 sites in United States
- Volunteers
- 153 people
- Sponsor
- BioDelivery Sciences International
Hip Arthroplasty, Knee Arthroplasty
Effect of Combined Use of Naloxone and Tramacet on Postop Analgesia in Elderly Patients Having Joint Replacement Surgery
Patients over 70 years of age, scheduled for joint replacement surgery will be randomized to tramacet/ naloxone plus morphine PCA or to morphine PCA to assess quality of analgesia in the postoperative period.
- Conditions
- Hip Arthroplasty, Knee Arthroplasty, Spinal Anesthesia
- Trial name
- NCT00679614
- Testing
- tramacet, naloxone, tramacet, Acetaminophen
- Where
- Canada
- Volunteers
- 45 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Recreational Drug Use
A Study to Evaluate the Intranasal Abuse Potential of PF614 in Non-Dependent Recreational Opioid Users (PF614-103)
The purpose of this study is to examine the abuse potential and pharmacokinetics of PF614 compared with a non-abuse deterrent, commercially available, immediate release (IR) oxycodone hydrochloride (HCl) formulation and placebo.
- Trial name
- NCT05567354
- Testing
- PF614, Oxycodone
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Ensysce Biosciences
Opiate Addiction
Efficacy of Computer Delivered Community Reinforcement Approach (CRA) (Bup II)
This study is designed to examine the effects of combined buprenorphine and voucher incentives to promote abstinence from illicit opiate use, along with or without computer-delivered therapy, during treatment of opioid dependence.
- Trial name
- CAT (NCT00929253)
- Testing
- Suboxone, CRA, Therapy
- Where
- United States
- Volunteers
- 170 people
- Sponsor
- Virginia Polytechnic Institute and State University
Healthy
Single-Dose, Crossover Study To Compare Bioavailability Of Two Formulations Under Fed And Fasted Conditions
To Compare The Bioavailability Of 40 Mg Doses Of Pf-00345439 Modified Formulation K Vs. Original Formulation X Under Fed And Fasting Conditions In Healthy Volunteers
- Trial name
- NCT02059915
- Testing
- Oxycodone
- Where
- United States
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Pain Therapeutics
Pain, Postoperative
Comparative Evaluation of Two Different Post-Operative Analgesia After Hallux Valgus Correction
Background: Recent studies showed the efficiency of several techniques of anesthesia in foot surgery. The new mini-invasive surgical approaches should require less analgesia and rapid motor recovery after surgery.
- Trial name
- NCT03396991
- Where
- Italy
- Volunteers
- 26 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Toothache
The Comparison of Supraperiosteal Nerve Block With Opiate Analgesia in Alleviating the Pain of Toothache
This study will compare the degree of pain control provided by two techniques for persons with toothache in an emergency department.
- Trial name
- NCT00574015
- Testing
- hydrocodone/acetaminophen, bupivacaine (supraperiosteal nerve block)
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Albany Medical College
HIV, Opiate Dependence
Project FIRST - Financial Incentives to Reduce Substance Use and Improve Treatment
This study will test whether contingency management (monetary vouchers contingent on abstinence from drugs) that reinforces one behavior (achieving abstinence from drugs) leads to improved outcomes in other related behaviors…
- Trial name
- Project FIRST (NCT01376570)
- Testing
- Abstinence-reinforcing contingency management intervention, Performance Feedback intervention
- Where
- 3 sites in United States
- Volunteers
- 242 people
- Sponsor
- Albert Einstein College of Medicine
Locally Advanced Head and Neck Cancer
Pilot Trial of Microsphere Oxycodone (Xtampza ER) for Pain Management in Patients Receiving Radiotherapy for Locally Advanced Head and Neck Cancer
To confirm the feasibility of studying Xtampza ER during radiotherapy (RT) for LAHNC as part of a prospective clinical trial.
- Trial name
- RAD 1702 (NCT03317730)
- Testing
- Xtampza ER
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- University of Alabama at Birmingham
Analgesic Adverse Reaction, Cesarean Delivery Affecting Newborn
Oxycodone in Serum After Postoperative Oral Oxycodone in Caesarean Sections Under Spinal Anesthesia
All patients undergoing an elective caesarean section under spinal anesthesia will, according to the hospital routines, receive 10 mg oxycodone slow-release tablet when arriving at our postoperative care unit (PACU).
- Trial name
- NCT02717637
- Where
- Norway
- Volunteers
- 50 people
- Sponsor
- University Hospital, Akershus
Hernia, Abdominal, Pain
Multimodal Pain Therapy After Hernia Repair
Investigating the effect of multimodal pain treatment after hernia repair
- Trial name
- NCT03792295
- Testing
- acetominophen, ibuprofen, oxycodone, Oxycodone
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Khashayar Vaziri
Cancer
PROspective Non-interventional Open laBEl Trial for TARGIN in Korean Patients With Cancer Pain
The aim of the study is to evaluate the efficacy of TARGIN administration as an analgesic to Korean patients treated with opioid analgesics for moderate-to-severe cancer pain under conditions of daily practice.
- Trial name
- PROBE (NCT01719757)
- Testing
- Oxycodone/Naloxone
- Where
- South Korea
- Volunteers
- 359 people
- Sponsor
- Mundipharma Korea Ltd
Joint Diseases, Arthritis
A Study to Compare the Frequency of Constipation Symptoms With Tapentadol Immediate Release (IR) Treatment Versus Oxycodone IR Treatment in Patients With End-stage Joint Disease
The purpose of this study is to compare bowel function/constipation that occurs during tapentadol treatment with that occuring during oxycodone treatment, as measured by the frequency of spontaneous bowel movements per week.
- Conditions
- Joint Diseases, Arthritis, Osteoarthritis
- Trial name
- NCT00784277
- Testing
- oxycodone CR, oxycodone IR, Tapentadol ER (CG5503)
- Volunteers
- 597 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Postoperative Pain, Postoperative Ileus
Effect of Liposomal Bupivacaine TAPB Combined With Oxycodone PCIA on Postoperative Gastrointestinal Recovery in Patients Undergoing Major Abdominal Surgery
Rationale and Objective: The purpose of this study is to evaluate the clinical efficacy and safety of a novel multimodal analgesia regimen, combining transversus abdominis plane block (TAPB) with patient-controlled intravenous…
- Trial name
- NCT07651722
- Testing
- ropivacaine hydrochloride, Liposomal bupivacaine (LB), Sufentanil citrate
- Where
- China
- Volunteers
- 132 people
- Sponsor
- Tianjin First Central Hospital