Clinical trials: Oxytocin
Sustained Positive Emotions, Sustained Positive Behavior Change
Study of Wellness Behaviors as a Function of Oxytocin vs Placebo
The specific aim of this study is to test whether oxytocin (OT) boosts the positive emotion yield of a new wellness behavior (Lovingkindness meditation or Mindfulness meditation) and thereby increases nonconscious motives that…
- Trial name
- NCT01929161
- Testing
- Oxytocin, Lovingkindness Meditation, Mindfulness Meditation
- Where
- United States
- Volunteers
- 239 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Healthy
Oxytocin's Effects on Face Attentional Processing
To investigate whether intranasal oxytocin (24IU) treatment has a regulatory effect on attentional processing of emotional faces.
- Trial name
- NCT04413786
- Testing
- oxytocin treatment
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
Healthy
The Neural Basis of Oxytocin's Effects on Empathy
The main focus of this study is to examine oxytocin effects on behavioral and neural indices of empathy processing.
- Trial name
- NCT03084029
- Testing
- Oxytocin
- Where
- China
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
Delivery
Carbetocin Versus Oxytocin in the Prevention of Post Partum Haemorrhage (PPH) in Women Delivered Vaginally With at Least 2 Risk Factors for Atonic PPH: A Randomised Controlled Trial
250 women will be randomly divided into 2 equal groups using computer generated random numbers. Group 1 will receive Carbetocin 100 µgm (Pabal® Ferring, UK) and group 2 will receive oxytocin 5IU (Syntocinon®, Novartis…
- Trial name
- PPH (NCT02304042)
- Testing
- Carbetocin, Oxytocin
- Where
- 2 sites in Egypt
- Volunteers
- 200 people
- Sponsor
- Cairo University
Autism Spectrum Disorder
Modulating Socially Adaptive Mirror System Functioning in Autism by Oxytocin
This study investigates the efficacy of a single-dose of exogenous oxytocin administration on socially adaptive mirror-motor mapping in participants with Autism Spectrum Disorders.
- Trial name
- NCT03640156
- Testing
- Oxytocin
- Where
- Belgium
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Premature Rupture of Membrane
Premature Rupture of Membranes at 34 to 37 Weeks' Gestation
Prelabour rupture of membrane is defined as rupture of membranes prior to the onset of labour. Approximately 8% of pregnant women at term experience PROM, but the decision as to how term PROM should be managed clinically remains…
- Trial name
- NCT03689062
- Testing
- induction of labor, follow up
- Volunteers
- 120 people
- Sponsor
- Assiut University
Healthy
Neural Correlates of Empathogenic and Affiliative Actions of Oxytocin
Mounting evidence indicates that the intranasal administration of the neuropeptide oxytocin has prosocial effects. However, the neural substrates of these effects are still unclear.
- Trial name
- ODIS (NCT01701180)
- Testing
- Oxytocin
- Where
- Germany
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bonn
Depressive Symptoms, Anxiety
Probiotics, Brain Structure and Psychological Variables
Theory and research on the gut-brain-axis emphasize complex interactions between the gut microbiota, immunological and hormonal responses, brain function, brain structure, as well as resulting behavioral manifestations, such as…
- Conditions
- Depressive Symptoms, Anxiety, Stress
- Trial name
- ProBrain01 (NCT03478527)
- Testing
- Vivomixx® powder
- Where
- Germany
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Animal Assisted Therapy
A Possible Effect of Oxytocin During Interaction Between Humans and Animals
The purpose of this pilot study is to investigate the possible change of Oxytocin level in human blood after positive interaction with farm animals.
- Trial name
- Oxytocin2010 (NCT01226017)
- Testing
- Measuring oxytocin level in blood
- Where
- Norway
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Life Sciences
Nicotine Dependence
The Gender-Sex Hormone Interface With Craving & Stress-Related Changes in Smoking
The purpose of the overall parent study is to determine the impact of gender and hormones (estradiol, progesterone, testosterone and cortisol) on responses to stress and smoking cues presented in daily, "real-world" cue…
- Trial name
- SCOR-III (NCT01576874)
- Testing
- Oxytocin
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- Kevin Gray, MD
Healthy Adult Participants
The Effects of Oxytocin on Fairness Perception and Related Prosocial Behaviors
This study aims to investigate the modulation of intranasally administered oxytocin (24 IU) on human fairness perception and related prosocial behaviors.
- Trial name
- NCT07815496
- Testing
- Oxytocin nasal spray
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
Healthy
Oxytocin and Resting State fMRI
The goal of the study is to investigate the effects of intranasal oxytocin (OT) or placebo to resting state brain activity in healthy males.
- Trial name
- NCT02689596
- Testing
- Oxytocin
- Volunteers
- healthy volunteers welcome
- Sponsor
- University Hospital Heidelberg
Bleeding Intraoperative
Comparative of Effects of Sublingual Misoprostol and Infusion Oxytocin in Reduction of Bleeding at Cesarean
The purpose of this study is to determine whether the effect of sublingual misoprostol is better than infusion oxytocin in reduction of blood loss at cesarean deliveries.
- Trial name
- NCT01477840
- Testing
- Misoprostol
- Where
- Iran
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Soudabeh Eshghi ali
Postpartum Hemorrhage
Prevention of Postpartum Haemorrhage With Sublingual Misoprostol or Oxytocin
Sublingual misoprostol produces rapid peak concentration and is more effective than oral misoprostol for prevention of excessive postpartum bleeding.
- Trial name
- NCT01373359
- Testing
- Misoprostol, Oxytocin
- Where
- India
- Volunteers
- 652 people
- Sponsor
- Jawaharlal Nehru Medical College
Irritable Mood
Dose Response Relationship of Oxytocin on Irritability in Youths
The proposed study is a randomized, double-blind proof of concept (PoC) study on the neural impact of intranasal oxytocin (OXT) administration for adolescents (age 14 to 18), demonstrating a clinically significant level of…
- Trial name
- NCT03863288
- Testing
- Functional MRI (fMRI), Oxytocin Intranasal Spray 8 International Unit (8IU), Oxytocin intranasal spray 24 International Unit (24IU)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Nebraska