Clinical trials: Paracetamol
Post Operative Pain, Acute, Bariatric Surgery Candidate
ZYNRELEF® for Postoperative Analgesia After Laparoscopic Sleeve Gastrectomy
Approximately 120 subjects will be randomized into 1 of the following 2 treatment groups in a 1:1 ratio: Group 1: ZYNRELEF® up to 200 mg/ 6mg ( 7ml vial) via instillation at all incision sites in addition to 30 ml of 0.5%…
- Conditions
- Post Operative Pain, Acute, Bariatric Surgery Candidate, Postoperative Pain
- Trial name
- HeronBariatric (NCT05863221)
- Testing
- ZYNRELEF 200Mg-6Mg Extended-Release Solution
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Dr. Yannis Raftopoulos
Anxiety, Pain
Strategy to Cope Pain and Discomfort in Mammography
Most of the women complain about the pain and discomfort during the mammography procedure. It is reported in the literature that most of the time these pain and discomfort are due to anxiety-related causes.
- Conditions
- Anxiety, Pain, Discomfort
- Trial name
- NCT04381104
- Testing
- Paracetamol
- Where
- Pakistan
- Volunteers
- 632 people
- Sponsor
- Dow University of Health Sciences
Low Back Pain
The Acute Effect of Kinesio Tape on Pain, Joint Range of Motion and Dynamic Balance in Patients With Low Back Pain
The aim of this study is to evaluate the acute effect of kinesio taping on pain, range of motion and dynamic balance in patients with chronic nonspecific low back pain.
- Trial name
- NCT06749821
- Testing
- Kinesio Tape, Control (no last irrigation)
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Istanbul Saglik Bilimleri University
Postoperative Dental Pain
A Study to Asses the Effect of MK0663 in the Treatment of Patients With Postoperative Dental Pain (0663-092)
The purpose of this study is to compare the pain relieving effect of different doses of MK0663 with placebo and other pain relievers/analgesics in patients with postoperative dental pain.
- Trial name
- NCT00694369
- Testing
- Comparator: etoricoxib, Comparator: ibuprofen, Comparator: acetaminophen + codeine
- Volunteers
- 588 people
- Sponsor
- Organon and Co
Tonsil Disease, Pain Management
Analgesic Effects of Intranasal Diclofenac Sodium, Ibuprofen, and Paracetamol in Pediatric Tonsillectomy Cases
This study aims to evaluate the efficacy and safety of intranasal Diclofenac Sodium, intranasal Ibuprofen, and intranasal Paracetamol for pain control following tonsillectomy in pediatric patients.
- Conditions
- Tonsil Disease, Pain Management, Intranasal Drug Administration
- Trial name
- NCT06731556
- Testing
- Intravenous paracetamol, Intranasal Paracetamol, Intranasal Diclofenac Sodium
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Bezmialem Vakif University
HIV Infections
Evaluation of the Interaction Between Acetaminophen and Zidovudine
To determine if zidovudine (AZT) and acetaminophen (APAP) interact when given to the same patient, and if so, the manner of interaction.
- Trial name
- NCT00000731
- Testing
- Zidovudine, Acetaminophen
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Pain
A Comparison of Amethocaine Cream vs. Liposomal Lidocaine Cream for Venipuncture in Children.
All patients undergoing venepuncture or venous cannulation in pediatric emergency department will be treated with either Amethocaine, or Liposomal Lidocaine (4%) cream at the site of cannulation in order to determine the efficacy…
- Trial name
- NCT00353002
- Testing
- Ametop (4% Amethocaine cream ), Maxilene (4% Liposomal Lidocaine)
- Where
- Canada
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Pain
Acute Pain Study Following Bunionectomy
The primary purpose of this study was to evaluate analgesic efficacy and safety of hydrocodone/acetaminophen extended release compared to placebo in the treatment of moderate to severe pain following bunionectomy.
- Trial name
- NCT01333722
- Testing
- Hydrocodone/Acetaminophen Extended Release
- Where
- 3 sites in United States
- Volunteers
- 100 people
- Sponsor
- AbbVie (prior sponsor, Abbott)
Hysterectomy, Laparoscopy
Optimization of Pre-operative Oral Analgesics in Patients Undergoing Ambulatory Minimally Invasive Hysterectomy
This is a randomized controlled trial comparing pre-admission administration of routine oral preoperative non-narcotic analgesics with the administration of these medications in the pre-anesthesia care unit per our standard…
- Conditions
- Hysterectomy, Laparoscopy, Analgesia
- Trial name
- NCT03420794
- Testing
- Timing of pre-operative oral non-narcotic analgesics in relation to minimally invasive hysterectomy
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Common Cold, Influenza
Evaluation of Efficacy and Safety of Oral Solution Resfenol in Reducing Symptoms of Common Cold And Flu
This study aimed to evaluate the efficacy and safety of the oral solution of paracetamol, chlorpheniramine maleate and phenylephrine hydrochloride in reducing symptoms of flu and the common cold.
- Trial name
- NCT01158326
- Testing
- Resfenol
- Where
- Brazil
- Volunteers
- 216 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Patent Ductus Arteriosus After Premature Birth
Selective Early Medical Treatment of Patent Ductus Arteriosus in Extremely Low Gestational Age Infants: A Pilot RCT
Background: Among preterm infants, those born at a gestational age less than 26 weeks are considered the most vulnerable with a high risk of short- and long-term health problems that include chronic lung disease, brain bleeds…
- Trial name
- SMART-PDA (NCT05011149)
- Testing
- Ibuprofen
- Where
- 9 sites in United States, Canada
- Volunteers
- 100 people
- Sponsor
- IWK Health Centre
Tuberculosis, Pulmonary
Adjunctive NAC in Adult Patients With Pulmonary Tuberculosis
To determine if adjunctive N-acetylcysteine 1200 mg twice a day (BID) accelerates sputum culture conversion and normalization of cellular glutathione in tuberculosis (TB), and to assess its potential effects on lung and immune…
- Trial name
- NAC-TB (NCT03702738)
- Testing
- N-acetyl cysteine
- Where
- Tanzania
- Volunteers
- 110 people
- Sponsor
- The Aurum Institute NPC
Acetaminophen Overdose, Pain
Investigation of Efficacy of Improved Acetaminophen Labeling
The purpose of this study is to evaluate, through brief, one-on-one cognitive interviews, the efficacy of 'enhanced' acetaminophen messages and icons in improving consumer understanding and use of prescription (Rx) and…
- Trial name
- NCT01592448
- Testing
- Active Ingredient Icon
- Where
- 4 sites in United States
- Volunteers
- 662 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Rib Fractures, Rib Fracture Multiple
US-guided SAPB for Rib Fractures in the ED
The purpose of this randomized controlled study is to determine whether the serratus anterior plane block reduces pain more than the usual treatment for rib fractures in the same amount of time.
- Trial name
- NCT03619785
- Testing
- Bupivacaine, Fentanyl, morphine, hydromorphone, hydrocodone, acetaminophen, ketorolac, gabapentin, ketamine, ibuprofen
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Andrew A Herring
Obesity
Incretin Physiology and Beta-cell Function Before and After Weight-loss
To evaluate the impact of laparoscopic adjustable gastric banding (LAGB) on beta-cell function, insulin sensitivity, incretin function, postprandial secretion of incretin hormones (glucagon-like peptide-1 (GLP-1) and…
- Trial name
- NCT00625040
- Testing
- Oral glucose tolerance test (OGTT), isoglycemic iv. clamp, liquid meal test, gastric emptying rate
- Where
- Denmark
- Volunteers
- 10 people
- Sponsor
- Glostrup University Hospital, Copenhagen
Undesired Intrauterine Pregnancy, First Trimester Pregnancy
Trial Comparing Intravenous and Oral Moderate Sedation for First Trimester Surgical Abortions
In the United States, the majority of first-trimester surgical abortions are performed in outpatient clinics that utilize a wide variety of oral and intravenous regimens for pain control.
- Trial name
- NCT01011634
- Testing
- Intravenous moderate sedation versus oral medication
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Breast Feeding, Analgesia
Breastfeeding Evaluation of Puerperal Women Who Had Cesarean Delivery in Our Hospital
İntroduction The World Health Organisation (WHO) and United Nations Children's Fund (UNICEF) recommends that infants are exclusively breastfed for a minimum of 6 months, with continued breastfeeding recommended until child age of…
- Trial name
- NCT06682871
- Testing
- Analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Konya City Hospital
Post-operative Pain
Effectiveness of Pre-emptive Analgesics on Post-Operative Pain After Stainless Steel Crown Placement On Primary Molars
The aim of this study is to evaluate the effectiveness of pre-emptive analgesia using ibuprofen and paracetamol on reducing post-operative pain following the placement of stainless steel crowns on primary molars compared to…
- Trial name
- NCT05602064
- Testing
- Ibuprofen, Paracetamol
- Where
- Egypt
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Inguinal Hernia
Awake Caudal Catheter vs General Anesthesia
It is well established that preterm inguinal hernias discovered in the NICU pose a significant surgical risk due to the associated co-morbid conditions that accompany these patients.
- Trial name
- NCT05919732
- Testing
- Bupivacaine, Dexmedetomidine, Caffeine, Tylenol, Propofol, rocuronium, caffeine, Tylenol, bupivacaine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Nemours Children's Clinic
Patent Ductus Arteriosus
Acetaminophen vs Indomethacin in Treating hsPDA
The purpose of this study is to see if acetaminophen (Tylenol) is as effective as indomethacin in closing patent ductus arteriosus in premature infants.
- Trial name
- NCT03537144
- Testing
- Indomethacin, Acetaminophen
- Where
- 3 sites in United States
- Volunteers
- 37 people
- Sponsor
- University of Tennessee
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