Clinical trials: Paracetamol, completed
Post-operative Pain
Oral vs Intravenous Acetominophen for Postoperative Pain in Minimally Invasive Gynecologic Surgery
Hypothesis: Postoperative pain will be equivalent in patients receiving preemptive oral acetaminophen as compared to patients receiving preemptive intravenous acetaminophen following minimally invasive benign gynecologic surgery.
- Trial name
- NCT03391284
- Testing
- acetominophen, Acetaminophen
- Where
- 2 sites in United States
- Volunteers
- 75 people
- Sponsor
- Scripps Health
COVID-19
Evaluation of Safety & Efficacy of MIR 19 ® Inhalation Solution in Patients With Mild COVID-19
The aim of this study is to evaluate the effectiveness and safety of MIR 19 ® in preventing development of moderate and/or severe course of the disease in mild COVID-19 outpatients.
- Trial name
- NCT05783206
- Testing
- MIR 19 ®, Standard therapy
- Where
- Russia
- Volunteers
- 984 people
- Sponsor
- National Research Center - Institute of Immunology Federal Medical-Biological Agency of Russia
Breast Cancer, Breast Cancer Female
PECS Block vs. Multimodal Analgesia for Prevention of Persistent Postoperative Pain in Breast Surgery
In this double blinded randomized placebo-controlled trial, 160 subjects scheduled for breast surgery involving the axilla will be administered a multimodal pain regimen including acetaminophen, dexamethasone, celecoxib, and…
- Conditions
- Breast Cancer, Breast Cancer Female, Cancer of Breast
- Trial name
- NCT03084536
- Testing
- Bupivacaine, Gabapentin, Celecoxib
- Where
- United States
- Volunteers
- 134 people
- Sponsor
- Washington University School of Medicine
Office Hysteroscopy
Efficacy of Oral Paracetamol Compared With Oral Ketoprofen for Pain Management in Office Hysteroscopy
Hysteroscopy is a procedure used to evaluate abnormalities within the uterus (intrauterine. Currently, hysteroscopy can be performed in an outpatient clinic setting according to established standards, known as office…
- Trial name
- NCT07315698
- Testing
- Ketoprofen 100mg, Paracetamol 1000 Mg Oral Tablet
- Where
- Indonesia
- Volunteers
- 60 people
- Sponsor
- Universitas Indonesia
Shivering
Comparative Study Between the Prophylactic Intravenous Administrations of Acetaminophen vs Dexamethasone vs Pethidine Regarding the Incidence of Shivering Induced by Single Shot Spinal Anesthesia in the Orthopedic Surgeries of the Lower Limbs
Single Shot Spinal anesthesia (SSSA) is associated with considerable perioperative shivering and can be challenging to treat. Some pharmacologic agents like N-methyl d-aspartate receptor antagonists, magnesium sulfate and opioid…
- Trial name
- NCT05284409
- Testing
- Pethidine, Acetaminophen, Dexamethasone
- Where
- Egypt
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Healthy
Interaction Between Paracetamol and Lamotrigine: A Clinical Interaction Study
The investigators will study the effect of paracetamol on the steady state metabolism of lamotrigine in 12 healthy male volunteers. Subjects will receive lamotrigine, slowly titrated from 25 mg daily to 100 mg daily over 28 days.
- Trial name
- NCT02303106
- Testing
- Lamotrigine
- Where
- Denmark
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Per Damkier
Arthroplasty, Replacement, Knee
Fast Track Total Knee Arthroplasty: Local Infiltration Analgesia vs Femoral Nerve Block
The objective of this study is to determine whether either a femoral nerve block (FNB) or local infiltration analgesia (LIA) is a better anesthetic technique to achieve optimal functional outcome after one year in patients…
- Trial name
- NCT01966263
- Testing
- LIA of the posterior capsule of the knee, LIA of the anterior capsule of the knee, LIA of the subcutaneous tissue of the knee
- Where
- Netherlands
- Volunteers
- 80 people
- Sponsor
- Sint Maartenskliniek
Respiratory Tract Infections, Fever
Placebo and Active Controlled Study to Compare the Antipyretic Efficacy of Aspirin® in Patients With Acute Febrile Upper Respiratory Tract Infections Suspected to be of Viral Origin
This study is addressed to patients suffering from an acute febrile upper respiratory tract infection suspected to be of viral origin.
- Trial name
- NCT01464944
- Testing
- Acetylsalicylic acid (Aspirin, BAYE4465), Paracetamol
- Where
- 9 sites in Russia, Ukraine
- Volunteers
- 392 people
- Sponsor
- Bayer
Overdose, Adverse Event
Consequences of Doing What Should Not be Done in Primary Care
Retrospective observational study in a random selection of 5% of digital records active between 2014 and 2017 to quantify the frequency of Do not do primary care recommendations, calculating the over-cost related to them and…
- Trial name
- SOBRINA (NCT03482232)
- Testing
- Benzodiazepines, Non-steroidal anti-inflammatory drugs, paracetamol
- Where
- 2 sites in Spain
- Volunteers
- 750,000 people
- Sponsor
- Universidad Miguel Hernandez de Elche
Pain
Pain Management Following Dental Treatment Under General Anesthesia
The main goal of this study is to test the efficacy of postoperative pain management for cases undergoing extractions of primary teeth under GA using a validated measure.
- Trial name
- NCT06574516
- Testing
- Ibuprofen 200 mg, paracetamol
- Where
- Jordan
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Acute Pain
A Study Evaluating Efficacy and Safety of VX-993 for Acute Pain After a Bunionectomy
The purpose of this study is to evaluate the efficacy, safety, tolerability and pharmacokinetics of VX-993 in treating acute pain after a bunionectomy.
- Trial name
- NCT06619847
- Testing
- VX-993, HB/APAP
- Where
- 14 sites in United States
- Volunteers
- 367 people
- Sponsor
- Vertex Pharmaceuticals Incorporated
Healthy
Effects of Oxybutynin Topical Gel on Gastric Emptying
This study explores the effect of oxybutynin topical gel on gastric emptying
- Trial name
- NCT00926926
- Testing
- Oxybutynin Chloride Gel
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Watson Pharmaceuticals
Post Operative Pain Management
A Novel Usage of Transdermal Scopolamine in Reducing Narcotic Usage in Outpatient Hand Surgery
The investigators will examine and analyze opioid narcotic usage patterns by requesting patients keep a two week log of their opioid usage following outpatient hand surgery with a standard analgesic regimen consisting of an…
- Trial name
- NCT04008264
- Testing
- Scopolamine Patch (Transderm V)
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- Alexander M Spiess, MD
Acute Myeloid Leukemia
A Dose Escalation and Expansion Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7283420.
This open-label, entry-into-human (EIH) study will evaluate the safety, tolerability, pharmacokinetics (PK), and pharmacodynamics of RO7283420.
- Trial name
- NCT04580121
- Testing
- RO7283420, Tocilizumab, Dasatinib
- Where
- 23 sites in United States, Australia and 8 more
- Volunteers
- 59 people
- Sponsor
- Hoffmann-La Roche
Pain, Postoperative
Postoperative Pain Management in Rhinoplasty
The primary purpose of the study is to determine adequacy of postoperative pain control after nasal surgery in patients prescribed Acetaminophen (325mg) + Hydrocodone (5mg) compared to Acetaminophen(325mg) + Ibuprofen (200mg)for…
- Trial name
- NCT03584152
- Testing
- Norco 5Mg-325Mg Tablet, Tylenol 325Mg Caplet, Ibuprofen 200 mg
- Where
- United States
- Volunteers
- 159 people
- Sponsor
- Stanford University
Tonsillectomy
Celecoxib After Tonsillectomy
Tonsillectomy is one of the most common pediatric surgical procedures in the United States. Postoperative pain is substantial, with typical regimens employing narcotic derivatives and acetaminophen for 1-2 weeks after surgery.
- Trial name
- NCT02934191
- Testing
- Celecoxib, Acetaminophen, Oxycodone
- Where
- United States
- Volunteers
- 172 people
- Sponsor
- Children's Hospital of Philadelphia
Education
The Effect of the Menstrual Belt Stress Ball on Pain in Women With Dysmenorrhea
This study will be conducted as a randomized controlled quasi-experimental study to determine the effect of hot massage menstrual belt and stress relief ball application on pain intensity in women with dysmenorrhea.
- Trial name
- NCT06949397
- Testing
- Change in VAS voice performance score following the characteristics of the menstrual cycle of two women
- Where
- Turkey (Türkiye)
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Istanbul Gedik University
Mandibular Anterior Crowding, Piezocision
Efficiency of Piezotome-Corticision Assisted Orthodontics
The aim of this study is to evaluate the hypothesis that a piezotome-corticision procedure will have a transient acceleratory effect on the rate of tooth alignment and the overall treatment time.
- Conditions
- Mandibular Anterior Crowding, Piezocision, Pain Perception
- Trial name
- NCT02026258
- Testing
- Piezotome-Corticision, Orthodontics
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- UConn Health
Pneumococcal Vaccines
Study Assessing the Effect of Medications to Prevent Fever on Prevenar 13®
The purposes of this study are assess the immunological response (measure the amount of antibodies, i.e. proteins that fight off germs) produced by children after they have been given the 13-valent pneumococcal vaccine (13vPnC)…
- Trial name
- NCT01392378
- Testing
- 13-valent pneumococcal conjugate vaccine, INFANRIX hexa, Paracetamol
- Where
- 14 sites in Poland
- Volunteers
- 908 people, healthy volunteers welcome
- Sponsor
- Pfizer
Pain
A Study of an Acetaminophen/Naproxen Sodium Fixed Combination, Acetaminophen and Naproxen Sodium in Postoperative Dental Pain
The purpose of this study is to evaluate how well a fixed combination of acetaminophen/naproxen sodium relieves postoperative dental pain compared with acetaminophen, naproxen sodium and placebo.
- Trial name
- NCT05761574
- Testing
- Acetaminophen/Naproxen Sodium Fixed Combination, Naproxen Sodium, Acetaminophen
- Where
- United States
- Volunteers
- 447 people
- Sponsor
- Johnson & Johnson Consumer Inc. (J&JCI)
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.