Clinical trials: Paracetamol, completed
Pain, Acute
Acetaminophen IV vs Hydromorphone IV in the ED
The purpose of the current study is to compare the analgesic efficacy of intravenous acetaminophen and intravenous hydromorphone in the treatment of acute pain in the ED.
- Trial name
- NCT03107481
- Testing
- Acetaminophen, Hydromorphone
- Where
- United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Pain, Postoperative, Lung Diseases
Efficacy of Intercostal CryoAnalgesia in Robotic Lung Resection
This is a single center, single surgeon, prospective, randomized trial examining the addition of Cryo Nerve Block during robot assisted thoracoscopic anatomic lung resection surgery
- Trial name
- NCT05144828
- Testing
- Intercostal Nerve Cryoablation, Patient-controlled analgesia (PCA)
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Medical College of Wisconsin
Healthy
A Relative Bioavailability Study of Acetaminophen 650 mg Extended Release Gelcaps Under Fasting Condition
The study was conducted as an open labeled, balanced, randomized, two-treatment, two-period, two-sequence, single-dose, crossover, bioavailability study comparing acetaminophen extended release gelcaps 650 mg of OHM Laboratories…
- Trial name
- NCT01073709
- Testing
- Acetaminophen
- Where
- India
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ranbaxy Laboratories Limited
Postoperative Pain
Intravenous Acetaminophen/Ibuprofen Fixed-dose Combination on Postoperative Opioid Consumption
This prospective, randomized, double-blinded study is designed to evaluate the postoperative analgesic effect of the intravenous acetaminophen/ibuprofen fixed-dose combination in patients undergoing video-assisted thoracic…
- Trial name
- NCT05366777
- Testing
- acetaminophen/ibuprofen fixed-dose combination, Saline
- Where
- South Korea
- Volunteers
- 96 people
- Sponsor
- Seoul National University Hospital
ACL Injury, Pain
Effect of Biophysical Stimulation on Intraspongious Bone Edema in Anterior Cruciate Ligament Reconstruction
The following study has as main objective to evaluate whether the use of I-ONE® therapy can reduce post-operative pain thanks to the modulation of inflammation in patients with bone bruise on the knee after anterior cruciate…
- Conditions
- ACL Injury, Pain, Magnetic Field Exposure
- Trial name
- NCT04255407
- Testing
- I-ONE® therapy, Anti-inflammatory drug
- Where
- Italy
- Volunteers
- 66 people
- Sponsor
- Istituto Ortopedico Rizzoli
Breast Cancer, Breast Cancer Female
PECS Block vs. Multimodal Analgesia for Prevention of Persistent Postoperative Pain in Breast Surgery
In this double blinded randomized placebo-controlled trial, 160 subjects scheduled for breast surgery involving the axilla will be administered a multimodal pain regimen including acetaminophen, dexamethasone, celecoxib, and…
- Conditions
- Breast Cancer, Breast Cancer Female, Cancer of Breast
- Trial name
- NCT03084536
- Testing
- Bupivacaine, Gabapentin, Celecoxib
- Where
- United States
- Volunteers
- 134 people
- Sponsor
- Washington University School of Medicine
Dementia, Alzheimer Disease, Pain
Pain Management and Behavioral Outcomes in Patients With Dementia
Dementia illness often co-exists with painful medical conditions associated with aging (e.g., degenerative joint disease, osteoarthritis, skin ulcers, back pain, headaches, cancer, or angina).
- Conditions
- Dementia, Alzheimer Disease, Pain, Behavior, Agitation
- Trial name
- NCT00012857
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- US Department of Veterans Affairs
Joint Pain, Knee Osteoarthritis
Efficacy and Safety of Celecoxib/Acetaminophen Versus Celecoxib for Diagnosed Osteoarthritis in Acute Exacerbation
This is a Phase III, longitudinal, multicenter, randomized, double-blind clinical trial designed to evaluate the efficacy and safety of a fixed-dose combination of celecoxib and acetaminophen compared to celecoxib monotherapy for…
- Conditions
- Joint Pain, Knee Osteoarthritis, Hip Osteoarthritis
- Trial name
- PRECEDENT (NCT06863636)
- Testing
- Celecoxib + Acetaminophen, Celecoxib
- Where
- Mexico
- Volunteers
- 231 people
- Sponsor
- Laboratorios Silanes S.A. de C.V.
Low Back Pain
Efficacy of the Combination of Ibuprofen and Paracetamol in Acute Non-specific Low Back Pain
The aim of the present study is to assess the efficacy and safety of paracetamol/ibuprofen Fixed Dose Combination (FDC) compared to ibuprofen in patients with uncomplicated non-specific acute low back pain after a 3-day treatment…
- Trial name
- NCT05222724
- Testing
- Tachifene, Brufen
- Where
- 11 sites in Italy, Poland
- Volunteers
- 176 people
- Sponsor
- Aziende Chimiche Riunite Angelini Francesco S.p.A
Pain
A Bioequivalence Study of Advil Dual Action Liquid Filled Capsules (125 mg/250 mg) Versus Advil Dual Action Caplets (125 mg/250 mg) and Bioavailability Assessment of Advil Dual Action Liquid Filled Capsules (125 mg/250 mg) and Advil Liqui-Gels (200 mg) in Healthy Adult Subjects
The primary purpose of this study is to demonstrate the bioequivalence of new formulation Advil Dual Action (ADA) liquid filled capsules (Test) compared to the currently marketed ADA Caplet (Reference) under fasted conditions and…
- Trial name
- NCT06802185
- Testing
- ADA Liquid Filled Capsules (Test Product), ADA Caplets (Reference Product), Advil Liqui-gels (Reference Product)
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- HALEON
Melanoma (Skin)
Combination Chemotherapy in Treating Patients With Stage III or Stage IV Melanoma
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells.
- Trial name
- NCT00003346
- Testing
- acetaminophen, acetylcysteine, carmustine
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Osteoarthritis
A Study of the Safety and Effectiveness of Orally Administered CR845 in Patients With Osteoarthritis of the Hip or Knee
To assess the safety and tolerability of orally-administered CR845 in patients with osteoarthritis (OA) of the hip or knee. The study drug is being tested to reduce OA pain, and will be taken twice a day for two weeks, with four…
- Trial name
- NCT02524197
- Testing
- CR845 0.25 mg, CR845 0.50 mg, CR845 1 mg
- Where
- 5 sites in United States
- Volunteers
- 81 people
- Sponsor
- Cara Therapeutics, Inc.
Pain
Ultrasound Guided Bilateral Erector Spinae Plane Block in Caesarean Delivery
Erector Spinae plane block (ESPB) is a regional anesthesia technique described three years ago. Its use for many indications has been identified by case reports in the literature.
- Trial name
- NCT04118413
- Testing
- erector spinae plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Cigli Regional Training Hospital
Healthy Volunteers
Paracétamol PMB by Sublingual et Buccal Routes
Paracetamol is the analgesic most used, indicated in the symptomatic treatment of fever and pain of mild to moderate. It comes in different dosage forms intended for oral, intravenous and rectal.
- Trial name
- NCT01206985
- Testing
- Von Frey electronic
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Covid19
TOCILIZUMAB - An Option for Patients With COVID-19 Associated Cytokine Release Syndrome; A Single Center Experience
Investigators conducted this study to see the effectiveness of Tocilizumab in COVID-19 participants who were in cytokine release syndrome and there was also a control group who received steroids(RECOVERY TRIAL wasn't published or…
- Trial name
- NCT04730323
- Testing
- Tocilizumab
- Where
- Pakistan
- Volunteers
- 93 people
- Sponsor
- FMH College of Medicine and Dentistry
Parkinson's Disease
Effect of Paracetamol on Opicapone Pharmacokinetics in Healthy Volunteers
Single-centre, open-label, randomised, two-way cross-over study consisting of 2 periods separated by a washout period of 14 days or more.
- Trial name
- NCT02305017
- Testing
- BIA 9-1067, Paracetamol
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Bial - Portela C S.A.
Periapical Abscess
Comparison of Two Combinations of Opioid and Non-opioid Analgesics for Acute Periradicular Abscess
Aim: The aim of this study was to compare the analgesic efficacy of two combinations of opioid and non-opioid analgesics for acute periradicular abscesses.
- Trial name
- NCT02750696
- Testing
- Fixed-dose oral tablet of codeine/ acetaminophen every 4 hours for 3 days, Fixed-dose oral tablet of tramadol/ acetaminophen every 4 hours for 3 days
- Volunteers
- 27 people
- Sponsor
- Federal University of Rio Grande do Sul
Patent Ductus Arteriosus
Oral Paracetamol Versus Oral Ibuprofen in Management of Patent Ductus Arteriosus in Preterm Infants: A Randomised Controlled Trial
The purpose of this study is to determine whether oral paracetamol or ibuprofen has a better or same efficacy and tolerance in closure of patent ductus arteriosus in preterm infants.
- Trial name
- NCT01536158
- Testing
- Oral paracetamol, Oral ibuprofen
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Zekai Tahir Burak Women's Health Research and Education Hospital
Fibromyalgia
Feasibility Study: fMRI Evaluation of Auricular PENFS for Fibromyalgia
Given recent increasing opioid-related deaths and evidence showing against the use of opioids for non-malignant chronic pain, there is growing need for non-narcotic pain management.
- Trial name
- fMRI (NCT03008837)
- Testing
- Military Field Stimulator, Standard Therapy
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- VA Office of Research and Development
Postoperative Pain Management, Obstetric Anesthesia
Effect of Bilateral Ultrasound-Guided TAP Block on Quality of Recovery in Cesarean Delivery Patients Receiving Intrathecal Morphine
This prospective, assessor-blinded observational cohort study will investigate the effect of adding bilateral ultrasound-guided transversus abdominis plane (TAP) block to standard intrathecal morphine (ITM) analgesia on the…
- Conditions
- Postoperative Pain Management, Obstetric Anesthesia, Recovery From Anesthesia
- Trial name
- QoR-TAP (NCT07145619)
- Testing
- Spinal Anesthesia with Intrathecal Morphine Only, Spinal Anesthesia with Intrathecal Morphine plus Bilateral TAP Block
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- MEHMET GÖKHAN TAFLAN
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.