Clinical trials: Paracetamol, completed
Pain, Postoperative
Transversus Abdominis Plane Block Versus Ilioinguinal Nerve Block for Pain Management in Inguinal Herniorraphy
This study compares efficacy of transversus abdominis plane block and ilioinguinal nerve block for postoperative pain in patients undergoing inguinal herniorraphy with spinal anesthesia.
- Trial name
- NCT02375100
- Testing
- Spinal Anesthesia, Transversus Abdominis Plane Block, Ilioinguinal Nerve Block
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Bozyaka Training and Research Hospital
Breast Diseases
Ultrasound Guided Erector Spinae Plane Block
Patients were randomized into two groups, ESP and control. Single-shot ultrasound (US)-guided ESP block with 20 ml 0.25% bupivacaine at the T4 vertebral level was performed preoperatively to all patients in the ESP group.
- Trial name
- NCT06657092
- Testing
- Erector Spinae Plane Block, Standart therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Gözde Gamze Uzun
Healthy
Influence of Age on the Absorption and Metabolism of Cocoa Flavanols
Accumulating evidence suggests that regular consumption of foods and beverages rich in flavanols, such as cocoa, tea, apples and wine, may have cardiovascular benefits.
- Trial name
- NCT01790009
- Testing
- Flavanol rich drink, Acetaminophen
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Reading
Postoperative Pain
Adjuvant Analgesic Effects of Low Dose Tramadol/Acetaminophen Combination After Open Gynaecological Surgery
Patient experience moderate to severe pain after abdominal surgery. This post-operative pain can also contribute to complications such as respiratory impairment, cardiovascular events, ileus, sleep deprivation and mood…
- Trial name
- NCT00942565
- Testing
- tramadol/acetaminophen, acetaminophen
- Where
- Hong Kong
- Volunteers
- 60 people
- Sponsor
- The University of Hong Kong
Pain, Postoperative
Preemptive Analgesia With Celecoxib for Acute Dental Pain Management
The purpose of this study is to compare the effect on postoperative pain of a single agent nonsteroidal anti-inflammatory drug (NSAID) [celecoxib plus placebo] to an NSAID combination [celecoxib plus acetaminophen] administered…
- Trial name
- NCT04790812
- Testing
- Celecoxib, Acetaminophen
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Acute Pain, Analgesics
Monitoring Side Effects Of Pain Medication Prescribing By Emergency Department In Patients Over 65
Half of the people over the age of 65 are not functioning at their optimal level because of interference from pain. > 50% of older adults had taken prescriptions of pain medication beyond a 6-month period.
- Conditions
- Acute Pain, Analgesics, Elderly
- Trial name
- MOSE65 (NCT02046681)
- Where
- 5 sites in Italy
- Volunteers
- 1,000 people
- Sponsor
- Azienda Ospedaliera S. Maria della Misericordia
Adverse Anesthesia Outcome
Preemptive Analgesia Using Intravenous Paracetamol
Dental treatment for children should be done in a calm atmosphere and without pain. Oral Propacetamol has been shown to be effective in a variety of postsurgical pain models.
- Trial name
- NCT02884921
- Testing
- Paracetamol
- Volunteers
- 87 people
- Sponsor
- Bnai Zion Medical Center
Pain, Postoperative
Intrathecal Paracetamol Before Spinal Anaesthesia With Chloroprocaine HCl 1% for Short Knee Procedures
This is a phase II, single centre, randomised, parallel-group, double-blind, three doses, placebo-controlled, exploratory efficacy and safety study.
- Trial name
- NCT03428230
- Testing
- 30 mg Paracetamol 3% (1 mL), 60 mg Paracetamol 3% (2 mL), 90 mg Paracetamol 3% (3 mL)
- Where
- Switzerland
- Volunteers
- 60 people
- Sponsor
- Sintetica SA
Lumbar Disc Herniation
QLB vs mTLIP for Lumbar Spinal Surgery
Ultrasound-guided quadratus lumborum block (QLB) is a fascial plane block where local anesthetic is injected adjacent to the quadratus lumborum muscle with the goal of anesthetizing the thoracolumbar nerves.
- Trial name
- NCT05217121
- Testing
- Quadratus Lumborum Block, Modified-thoracolumbar interfascial plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Medipol University
Trauma, Flail Chest
Operative Treatment of Unstable Thoracic Cage Injuries and Chest Wall Deformity in Trauma
The purpose of this prospective controlled study is to determine whether surgical management of unstable thoracic cage injuries and chest wall deformity in trauma reduces the need for and the time spent on ventilator compared to…
- Conditions
- Trauma, Flail Chest, Rib Fractures, Surgery
- Trial name
- NCT02132416
- Testing
- NSAID, Opioids, Thoracic Epidural anaesthesia
- Where
- 2 sites in Sweden
- Volunteers
- 92 people
- Sponsor
- Sahlgrenska University Hospital
Chronic Rhinosinusitis (Diagnosis)
Effect of Post-operative Ibuprofen After Surgery for Chronic Rhinosinusitis
Endoscopic sinus surgery (ESS) for chronic rhinosinusitis (CRS) is a common procedure in the US, with about 250,000 cases performed annually.
- Trial name
- NCT03055507
- Testing
- Ibuprofen 400 mg, Acetaminophen 650 mg, OxyCODONE 5 Mg Oral Tablet
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Washington
Analgesia, Renal Colic
Comparison of the Analgesic Efficacy of Dexketoprofen Trometamol, Meperidine, and Paracetamol in Renal Colic
This study aimed to compare the effectiveness of intravenous (IV) dexketoprofen trometamol, IV meperidine, and IV paracetamol as analgesics for renal colic in patients at the Emergency Department of Erciyes University Medical…
- Trial name
- NCT06558916
- Testing
- Dexketoprofen Trometamol, Meperidine Injectable Solution, Paracetamol
- Volunteers
- 90 people
- Sponsor
- Ismail Tekin
Acute Pain, Neck Pain
Effect of Biofreeze® Versus Placebo on Acute Neck Pain, Disability, and Range of Motion
The purpose of this study to compare the effect of Biofreeze® versus a Placebo on neck pain, disability, fear avoidance, and range of motion prior to and following cervical manipulation over the course of one week among patients…
- Trial name
- NCT03157349
- Testing
- Biofreeze
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- Sport and Spine Rehab Clinical Research Foundation
Cholelithiasis, Pain, Postoperative
Postoperative Pain Will be Compared in Cholecystectomy Patients: Half Receiving TAP Block and Half Without it.
This study compares the effectiveness of a Transversus Abdominis Plane (TAP) block in reducing post-operative pain for patients undergoing laparoscopic cholecystectomy.
- Trial name
- NCT07465406
- Testing
- Bupivacaine 0.25%, Standard Post-Operative Care
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Darul Sehat Hospital
Hip Arthropathy
Impact of Opioid Free Anesthesia on Outcome After Hip Arthroplasty by Direct Anterior Approach.
all patients with a first anterior arthroplasty, give their informed consent to be randomized to control or study protocol. control means no high steroid dose, opioids for anesthesia; paracetamol, NSAIDs and opioids as analgesia.
- Trial name
- NCT03663426
- Testing
- study group, control
- Where
- Belgium
- Volunteers
- 42 people
- Sponsor
- AZ Sint-Jan AV
Severe Acute Pancreatitis
Epidural Analgesia for Pancreatitis (Epipan Study)
Acute pancreatitis (AP) is a common disease whose incidence in the US reaches 35 per 100,000 population annually. Its main causes in adults are gallstone migration into the common bile duct and alcohol abuse.
- Trial name
- EPIPAN (NCT02126332)
- Testing
- ropivacaine and sufentanil, acetaminophen, nefopam, tramadol, opidoids
- Where
- France
- Volunteers
- 148 people
- Sponsor
- University Hospital, Clermont-Ferrand
Nurse's Role
Laughter Therapy and Mindfulness Practices
Nurses working by shifts under intense stress and pressure and using complicated technological products- undergo fatigue and attention deficit with the effect of the many negative factors caused by work setting.
- Trial name
- NCT05634343
- Testing
- experimental group 1, experimantal group 2
- Where
- Turkey (Türkiye)
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Nagihan Koroglu Kaba
Pain
Study to Evaluate the Analgesic Efficacy and Safety of Hydrocodone Bitartrate/Acetaminophen Immediate-Release Tablets in Participants With Moderate to Severe Pain Following Bunionectomy
The primary objective of this study is to evaluate the analgesic efficacy of hydrocodone bitartrate/acetaminophen immediate-release tablets at doses of 5.0 milligrams (mg)/325 mg, 7.5 mg/325 mg, and 10 mg/325 mg every 4 to 6…
- Trial name
- NCT02487108
- Testing
- TV-46763
- Where
- 8 sites in United States
- Volunteers
- 569 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Placebo Effect, Drug Half Life
The Placebo Effect May Involve Modulating Drug Bioavailability
The total effect of a medication is the sum of its drug effect, placebo effect (meaning response of placebo), and their interaction.
- Conditions
- Placebo Effect, Drug Half Life, Pharmacokinetics
- Trial name
- NCT01501747
- Testing
- Caffeine, paracetamol, cephalexin, or ibuprofen
- Where
- Saudi Arabia
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- King Faisal Specialist Hospital & Research Center
Lumbar Spinal Stenosis, Lumbar Disc Herniation
Clinical Effect of Preventive Use of Tylenol on Fever After Removal of Drainage Tube in Lumbar Fusion Surgery
This study evaluates the influence of Non-steroidal Anti-inflammatory Drugs on preventing fever after the removal of drainage tube in the patients who suffered lumbar fusion surgery, if the outcome turn out positive, the…
- Conditions
- Lumbar Spinal Stenosis, Lumbar Disc Herniation, Lumbar Radiculopathy
- Trial name
- NCT04042948
- Testing
- Tylenol
- Where
- China
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
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