Clinical trials: Physical Therapy
Cerebral Palsy
IMPACT of an Instrumented Measurement on a Performance Assessment in Cerebral Palsy Treatment
The goal of this study is to assess the impact of passive reflective markers on bimanual performance assessment scores in children with unilateral cerebral palsy.
- Trial name
- IMPACT² (NCT06565000)
- Testing
- AHA Not Instrumented then AHA Instrumented, AHA Instrumented then AHA Not Instrumented
- Where
- France
- Volunteers
- 18 people
- Sponsor
- Centre Médico-Chirurgical de Réadaptation des Massues Croix Rouge Française
Colon Adenocarcinoma, Colorectal Carcinoma
Young-Onset Colorectal Cancer
This study investigates the genetic factors that may influence the risk of developing colorectal cancer at a young age. Finding genetic markers for colorectal may help identify patients who are at risk of colorectal cancer.
- Conditions
- Colon Adenocarcinoma, Colorectal Carcinoma, Rectal Adenocarcinoma
- Trial name
- NCT02863107
- Testing
- Biospecimen Collection, Medical Chart Review, Quality-of-Life Assessment
- Where
- 5 sites in United States
- Volunteers
- 818 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Lower Limb Amputation
Transcutaneous Electrical Stimulation in Lower Limb Amputees
Current lower limb prostheses support ambulation by absorbing and stabilizing positions during walking. Users of lower limb prostheses rely solely on sensory information provided by the contact between the socket and the residual…
- Trial name
- NCT06160336
- Testing
- Transcutaneous Electrical Nerve Stimulation
- Where
- Italy
- Volunteers
- 13 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Functional Constipation, Gastrointestinal Disease
Efficacy and Safety of Vibrating Capsule in Patients With Functional Constipation
The safety and efficacy of vibrating capsule (VC) in promoting defecation by mechanical stimulation of the gastrointestinal walls have been elucidated in animal studies and pilot clinical studies.
- Conditions
- Functional Constipation, Gastrointestinal Disease, Capsule Endoscopy
- Trial name
- NCT04671264
- Testing
- Sallowing VC during six weeks
- Where
- China
- Volunteers
- 107 people
- Sponsor
- Changhai Hospital
Hypertension, Elevated Blood Pressure
Blood Pressure Following Isometric Exercise in Inactive Adults
This study investigates how isometric exercise training (IET) affects blood pressure in physically inactive adults. Isometric exercise involves sustained muscle contractions without movement-for example, pushing against a fixed…
- Conditions
- Hypertension, Elevated Blood Pressure, Sedentary Lifestlye
- Trial name
- BELIEF-BP (NCT06937164)
- Testing
- Isometric Exercise Training (IET), Expectation-Enhancing Informational Framing
- Where
- United Kingdom
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Canterbury Christ Church University
Metabolic Syndrome, Insulin Resistance
Asprosin and miRNA Expression in Young Women With Metabolic Syndrome
Metabolic syndrome is a major risk factor for cardiovascular disease and type 2 diabetes, and its prevalence in young adults is increasing. Early identification of individuals at risk may improve prevention strategies.
- Conditions
- Metabolic Syndrome, Insulin Resistance, Obesity, Abdominal, Dyslipidemias
- Trial name
- ASPRO-MetS (NCT07917364)
- Testing
- Biomarker panel (asprosin, microRNA, BDNF, cortisol), Clinical and questionnaire assessment
- Where
- Poland
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Applied Sciences in Nowy Targ
Diabetic Foot Ulcer
Phase 2a Multi-Center Prospective, Randomized Trial to Evaluate the Safety & Efficacy of Topical PEP-TISSEEL for Diabetic Foot Ulcers (DFU)
This is a Phase 2a Multi-Center, Prospective, Randomized, Controlled Study aimed to evaluate the Safety and Efficacy of Topically Applied PEP-TISSEEL in Subjects with Diabetic Foot Ulcers (DFU)
- Trial name
- NCT06319287
- Testing
- PEP (Purified Exosome Product) / TISSEEL
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- Rion Inc.
Haemochromatosis
Impact of Transferrin Saturation Guided Maintenance Treatment on Quality of Life in HFE Haemochromatosis
Patients in maintenance treatment for HFE hemochromatosis since at least one year will be included in a two year study period and randomized in two groups experimental and control group.
- Trial name
- Quali-SAT (NCT04779593)
- Testing
- Clinical examination, SF36 questionnaire, AIMS2_SF questionnaire
- Where
- 12 sites in France
- Volunteers
- 239 people
- Sponsor
- Rennes University Hospital
Fibromyalgia Syndrome
Effect of Neuromodulation on Pain Biomarkers and Functional Outcome in Patients With Fibromyalgia Syndrome
Fibromyalgia is the third most common musculoskeletal condition in terms of prevalence, after lumbar pain and osteoarthritis. Its prevalence is around 2-4 % and is more frequent in women than in men; the prevalence is highest in…
- Trial name
- NCT06539793
- Testing
- Aerobic Exercises, Transcutaneous electrical nerve stimulation
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Ahmed Alshimy
Postoperative Pain After Limb Lengthening, Limb Lengthening
Pain Beliefs and Functional Performance After Cosmetic Limb Lengthening Using the Lengthening Over Nail (LON) Technique
This pilot observational study aims to examine the relationship between pain beliefs, pain intensity, and functional performance in individuals who have undergone cosmetic lower limb lengthening surgery using the Lengthening Over…
- Trial name
- LON-PILOT (NCT07438821)
- Testing
- Postoperative Functional and Pain Assessment
- Volunteers
- 58 people
- Sponsor
- Istanbul Aydın University
Septic Shock
The Cooling And Surviving Septic Shock Study (CASS)
Septic shock is in critically ill patients is a condition associated with a high rate of organ failure and hereto attributable mortality ~45-55% Hypothesis: Mild Induced Hypothermia reduces the mortality of critically ill…
- Trial name
- CASS (NCT01455116)
- Testing
- Mild Induced Hypothermia
- Where
- 11 sites in United States, Denmark and 1 more
- Volunteers
- 433 people
- Sponsor
- Danish Procalcitonin Study Group
Type 2 Diabetes, Patient Engagement
The Effect of The Personalized Patient Engagement Plan on Diabetes Management
This study evaluates the effect of Personalized Patient Engagement Plan on diabetes management in patients with at least six months of Type-2 Diabetes.
- Conditions
- Type 2 Diabetes, Patient Engagement, Self Efficacy, Adherence, Patient
- Trial name
- NCT04256304
- Testing
- PHEinAction-Personalized Patient Engagement Plan
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 59 people
- Sponsor
- Hacettepe University
Yaws
Effect of WHO-yaws Elimination Strategy in Lihir Island, Papua New Guinea
The trial that the investigators are proposing is a pilot study to determine the effect of the new WHO-yaws eradication strategy in Lihir Island (population 18,000), Papua New Guinea.
- Trial name
- YESA-13 (NCT01955252)
- Testing
- Azithromycin
- Where
- Papua New Guinea
- Volunteers
- 16,000 people
- Sponsor
- Lihir Medical Centre
Hepatobiliary Cancer, Cholangiocarcinoma
Senior Adult Hepatobiliary Prehab Study
The purpose of the study is to evaluate an exercise program for individuals with hepatobiliary cancer planning for surgery.
- Conditions
- Hepatobiliary Cancer, Cholangiocarcinoma, Liver Metastases
- Trial name
- NCT05921552
- Testing
- Resistance Training, Aerobic Training
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Acquired Brain Injury
Does Improved Ability to Achieve Single Leg Stance Lead to a More Efficient Gait Pattern in Adults With Acquired Brain Injury?
The purpose of the study is to see if a person can stand better on their weaker leg does this improve their walking ability following treatment specifically aimed at standing on leg.
- Trial name
- NCT04062149
- Testing
- single leg stance treatment, Usual physiotherapy
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Manchester University NHS Foundation Trust
Patients (>=60 Years Old) Suffering From Mild-moderate Stroke (Ischemic or Hemorrhagic, Stroke Severity Assessed by NIHSS <16 Points)
IMAGINE Study Protocol
Background: Rehabilitation pathways are crucial to reduce stroke-related disability. Motivational Interviewing (MI), a centred-person intervention aimed to empower and motivate the patient, could be a resource to improve…
- Trial name
- IMAGINE (NCT03434938)
- Testing
- Motivational interviewing
- Where
- 6 sites in Spain, Sweden
- Volunteers
- 272 people
- Sponsor
- Parc Sanitari Pere Virgili
Pain, Sickle Cell Disease
Peer Support for Adolescents and Emerging Adults With Sickle Cell Pain
The study, known as the Peer suppoRt for adolescents and Emerging adults with Sickle cell pain: promoting ENgagement in Cognitive behavioral thErapy (PRESENCE), aims to determine the effectiveness of digital CBT in reducing pain…
- Trial name
- PRESENCE (NCT06374238)
- Testing
- CBT+ Health coach, CBT w/o Health Coach ( self-guided), Usual Care
- Where
- 14 sites in United States
- Volunteers
- 390 people
- Sponsor
- University of Pittsburgh
Spastic Hemiplegic Cerebral Palsy
Pelvic Proprioceptive Neuromuscular Facilitation on Trunk Control and Balance
The study will be randomized controlled trial. This study will be conducted in Children Hospital Pakistan. A sample size of 60 will be randomly allocated into two groups, (30 participants in each group), by lottery method.
- Trial name
- NCT05261048
- Testing
- Pelvic Proprioceptive neuromuscular facilitation in addition to Conventional Physical Therapy, Conventional Physical Therapy
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- University of Lahore
Osteoporosis Diagnosis
Bone Evaluation by Ultrasound Radiofrequency Echographic Multi Spectrometry (REMS) vs Dual X-ray Absorptiometry (DXA)
Bone Density Evaluation by means of the Ultrasound Technology Named Radiofrequency Echographic Multi Spectrometry (REMS) in Comparison With DXA Technique.
- Trial name
- NCT06371755
- Testing
- Ultrasound examination with REMS technology
- Where
- Italy
- Volunteers
- 296 people, healthy volunteers welcome
- Sponsor
- Paola Pisani
Bruxism, Wear, Occlusal
Effect of Bruxism on the Clinical Success of Posterior Composite Restorations
The goal of this study is to determine the effect of bruxism on the success of posterior composite restorations (PCRs) in endodontically treated teeth (ETT).
- Conditions
- Bruxism, Wear, Occlusal, Fracture
- Trial name
- Bruxism (NCT06881355)
- Testing
- Bruxism diagnosis, Clinical evaluation
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Muğla Sıtkı Koçman University
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