Clinical trials: Physical Therapy
Hematologic Malignancy, Stem Cell Transplantation
Physiotherapy in Hematopoietic Stem Cell Transplantation
Research project with patients undergoing allogeneic hematopoietic transplantation in the hematology and hemotherapy Clinical Hospital Universitario Virgen de la Arrixaca.
- Trial name
- TRAS (NCT02193399)
- Testing
- Physiotherapy in patients with stem cell transplantation
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Universidad Católica San Antonio de Murcia
Sickle Cell Anemia
EXTEND EXpanding Treatment for Existing Neurological Disease
The primary goal of the Phase II EXTEND trial is to investigate the effects of open-label hydroxyurea treatment, escalated to maximum tolerated dose, for children with Sickle Cell Anemia and either conditional (170 - 199 cm/sec)…
- Trial name
- NCT02556099
- Testing
- Hydroxyurea
- Where
- Jamaica
- Volunteers
- 43 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Urticaria
Study to Investigate Safety, Tolerability, Pharmacodynamics and Pharmacokinetics of GSK2646264
This First Time in Human (FTIH) study, which will be performed in three parts, is designed to investigate the safety, local tolerability, pharmacokinetics and pharmacodynamics after single and repeat topical applications of up to…
- Trial name
- NCT02424799
- Testing
- GSK2646264 0.5% topical cream, GSK2646264 1% topical cream
- Where
- 6 sites in Germany, United Kingdom
- Volunteers
- 34 people
- Sponsor
- GlaxoSmithKline
Glioblastoma
Multimodal Imaging Analysis During Treatment With Bevacizumab in Patients With Recurrent Glioblastoma
The purpose of this study is to estimate the capacity of the multimodal imaging parameters measured at 15 days and 2 months of initiation of treatment with bevacizumab, to measure changes in clinical status (sensitivity to…
- Trial name
- IMAGLIO (NCT02841332)
- Testing
- F-MISO, Cerebral magnetic resonance imagery, Bevacizumab
- Where
- France
- Volunteers
- 6 people
- Sponsor
- University Hospital, Toulouse
Breast Cancer-related Subclinical Lymphedema
Subclinical Lymphedema Treatment Study
Primary Objective To compare the effectiveness of 2 treatment protocols for patients with breast cancer-related subclinical lymphedema identified through bioimpedance spectroscopy, L-dex scores Secondary Objectives To determine…
- Trial name
- SLT (NCT03292198)
- Testing
- 20-30 mmHg compression sleeve and gauntlet, Manual Lymphatic Drainage
- Where
- United States
- Volunteers
- 267 people
- Sponsor
- Mercy Research
Smoking Cessation, Weight Loss
Comparing Two Treatments That Both Target Smoking Cessation and Weight Loss at the Same Time.
The study has two phases. In Phase 1, the investigators will revise and pilot the distress tolerance (DT) protocol that was originally developed and piloted in a previous study (2P20 GM103430, Spas, PI).
- Trial name
- BREATH (NCT04130698)
- Testing
- Distress Tolerance, transdermal nicotine patch, Active Health Control
- Where
- United States
- Sponsor
- Rhode Island College
Acute Lymphoblastic Leukemia
Treatment of Childhood Acute Lymphoblastic Leukemia
The purpose of this study is to reduce the side-effects and discomfort of anti-leukemia therapy, to attain long-term control of the disease and to hopefully eradicate it.
- Trial name
- NCT00165087
- Testing
- asparaginase (E. Coli), asparaginase (Erwina), dexrazoxane
- Where
- 10 sites in United States, Canada and 1 more
- Volunteers
- 491 people
- Sponsor
- Dana-Farber Cancer Institute
Sleep Disorders, Sciatica
Intravascular Laser and Electroacupuncture for Sciatica With Insomnia: A Pilot Trial
Sciatica is a common condition worldwide, with prevalence rates ranging from 1.2% to 43%. Chronic sciatica is often associated with sleep disturbances, forming a bidirectional loop where persistent nociceptive input disrupts…
- Trial name
- NCT06755593
- Testing
- Electroacupuncture, Intravascular Low-Level Laser Therapy (ILIB)
- Where
- Vietnam
- Volunteers
- 66 people
- Sponsor
- Le Hoang Minh Quan
Temporomandibular Disorders (TMD)
Transcutaneous Electrical Nerve Stimulation for Early Pain Control in Temporomandibular Disorders
To evaluate whether adding conventional transcutaneous electrical nerve stimulation (TENS) to a standard conservative regimen (patient education, pharmacotherapy, and a home exercise programme) provides additional short- and…
- Trial name
- NCT07744893
- Testing
- Standard Conservative Therapy, Transcutaneous Electrical Nerve Stimulation (TENS)
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Balikesir University
Paroxysmal AF, Treatment Decisions
Comparative Efficacy of 100-, 200-, & 400-mg Amiodarone in Patients With Paroxysmal AF Depending on Plasma Concentration
Amiodarone is a highly effective drug for the treatment and prevention of arrhythmias. In the 1970s and 1980s, numerous experimental and clinical studies comprehensively examined the mechanisms of amiodarone's antiarrhythmic…
- Conditions
- Paroxysmal AF, Treatment Decisions, Therapeutic Drug Monitoring (TDM)
- Trial name
- AMIODETECT (NCT07487714)
- Testing
- Pharmacotherapy with amiodarone 200 mg per day, Treatment with Amiodarone at a dose 100 mg per day, Treatment with Amiodarone at a dose 400 mg per day
- Where
- Russia
- Volunteers
- 80 people
- Sponsor
- Tomsk National Research Medical Center of the Russian Academy of Sciences
Meningioma, Radiation Toxicity
Neurocognitive Impact of Different Irradiation Modalities for Patients With Grade I-II Skull Base Meningioma:
For the purpose of this research, investigator will constitute several cohorts of patients, treated either by intensity-modulated radiotherapy, stereotactic radiotherapy or proton-therapy.
- Trial name
- CANCER-COG (NCT06036706)
- Testing
- Normo-fractionated intensity-modulated brain irradiation with or without stereotactic positioning, Hypo-fractionated stereotactic brain irradiation, Normo-fractionated proton therapy brain irradiation
- Where
- 3 sites in France
- Volunteers
- 108 people
- Sponsor
- Centre Francois Baclesse
Bone Cysts
Aneurysmal Bone Cyst Imaging After Interventional Radiology Treatment
This study aims to describe the clinical outcomeand the radiological appearance of aneurysmal bone cyst treated by means of interventional radiology procedures (percutaneous sclerosis and endovascular embolization)
- Trial name
- KOA-RI (NCT05075148)
- Testing
- radiology
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Montpellier
Cirrhosis, Liver, Cirrhotic Cardiomyopathy
Echocardiography-guided Cirrhosis and Liver Failure-Intensive Care Protocol Sepsis
Point-of-care echocardiography is used to guide septic shock resuscitation in patients with severe sepsis in the intensive care unit (ICU), but without systematic evidence for efficacy in critically patients with Cirrhosis and…
- Conditions
- Cirrhosis, Liver, Cirrhotic Cardiomyopathy, Septic Shock
- Trial name
- ECLIPSE-I (NCT07286643)
- Testing
- POCUS, Fixed Resuscitation Strategy based on Target MAP
- Where
- India
- Volunteers
- 140 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Cerebral Palsy
Myofascial Release and Sustained Stretching in Spastic CP Children
The aim of this research was to find and compare the effects of Myofascial Release Technique and Passive Sustained Stretching on Hamstrings Flexibility in Children with Spastic Cerebral Palsy.
- Trial name
- NCT05251025
- Testing
- Passive sustained stretching, Myofascial Release
- Where
- Pakistan
- Volunteers
- 26 people
- Sponsor
- Riphah International University
Difficulties, Ambulation, Brain Injuries, Traumatic
Walking and Balance Post-TBI
This is a case series study evaluating the feasibility and dosage of Intensive Mobility Training (IMT). Twelve participants with chronic, mild-to-moderate, Traumatic Brain Injury (TBI) causing significant locomotor impairment…
- Trial name
- NCT01418976
- Testing
- Intensive Mobility Training (IMT)
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- INTRuST, Post-Traumatic Stress Disorder - Traumatic Brain Injury Clinical Consortium
Caregiver Burnout, Caregiver Stress
Mindful-Compassion Art Therapy for Dementia Care (MCAT-DC) : A Waitlist Randomized Controlled Trial
The current study builds on the empirical foundation of Mindful-Compassion Art Therapy (MCAT) to test its efficacy as a multicomponent, holistic, psycho-socio-spiritual intervention for supporting dementia family caregivers.
- Trial name
- NCT04548089
- Testing
- Mindful-Compassion Art Therapy for Dementia Care (MCAT-DC)
- Where
- 3 sites in Singapore
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Nanyang Technological University
Lumbar Radiculopathy
PNE With Therapeutic Exercises on Pain Intensity in Lumbar Radiculopathy
There is lack of structured pain neuroscience education in patients with lumber radiculopathy. Previously researches were done on pain neuroscience education before surgery of lumber radiculopathy.
- Trial name
- NCT05356468
- Testing
- Structured pain neuroscience education, Conventional Treatment
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Riphah International University
Cancer, Radiation Therapy
Capturing Food Intake in Patients Undergoing Radiation Therapy for Cancer
The purpose of this study is to determine the feasibility of capturing daily dietary intake of patients undergoing radiation therapy using a mobile food record.
- Conditions
- Cancer, Radiation Therapy, Dietary Intake
- Trial name
- NCT07682714
- Testing
- Mobile food record using myCircadian Clock app
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Minnesota
Developing a Consensus Framework to Standardize Isokinetic Testing Data Reporting
Standardizing Reporting Practices for Isokinetic Testing: a Delphi Study
Isokinetic testing plays a crucial role in research and clinical practice, particularly for evaluating muscle strength, functional performance, and imbalances between muscle groups in fields such as rehabilitation, sports…
- Trial name
- NCT06733116
- Testing
- Delphi method survey
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Large B-cell Lymphoma, B-cell Lymphoma
An Open-Label, Single Center Phase 2 Study of Magrolimab, Rituximab and Radiation as Bridging Strategy Before CAR T-Cell Therapy in Patients With Relapsed or Refractory Large B-cell Lymphoma
To evaluate the efficacy of the combination of magrolimab, rituximab, and radiation as bridging therapy in patients with relapsed or refractory LBCL who receive CAR T-Cell Therapy (CART).
- Trial name
- NCT05929716
- Testing
- Magrolimab, Rituximab, CAR T leukapheresis
- Sponsor
- M.D. Anderson Cancer Center
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