Clinical trials: Physical Therapy
Down Syndrome
Dual Task Balance Exercises and Vestibular Stimulation for Children With Down Syndrome
Children with Down syndrome experience balance and postural control issues due to neuromuscular defects and face several impairments.
- Trial name
- NCT06998199
- Testing
- Dual Task Balance Exercise, Vestibular Stimulation
- Where
- Pakistan
- Volunteers
- 26 people
- Sponsor
- Riphah International University
Locally Advanced Rectal Cancer, Older People
Efficacy and Safety of Conventional Neoadjuvant Therapy Versus Total Neoadjuvant Therapy in Older Patients With Locally Advanced Rectal Cancer
The SHAPERS study is a multicentre, open-label, randomised, pragmatic clinical trial, comparing standard-of-care neoadjuvant treatment options for older (i.e., ≥70 years) subjects with high-risk stage II and stage III rectal…
- Trial name
- SHAPERS (NCT06052332)
- Testing
- Short course radiotherapy, Adjuvant chemotherapy (optional), Total mesorectal excision
- Where
- 19 sites in Belgium
- Volunteers
- 230 people
- Sponsor
- Jules Bordet Institute
Overweight, Obesity
Maâthermes: Spa Treatment for Overweight and Obesity
Public health campaigns and industry-supported changes in our food supply have obviously failed to control the epidemic to date.
- Trial name
- MAATHERMES (NCT01258114)
- Testing
- SPA treatment (ST), Non SPA treatment (NST)
- Where
- 5 sites in France
- Volunteers
- 400 people
- Sponsor
- Association Francaise pour la Recherche Thermale
Aortic Valve Disease, Pulmonary Valve Disease
Artificial Intelligence in New Cardiac MR Markers for Congenital Heart Disease
The goal of this study is to investigate children with aortic and pulmonary valve disease treated or untreated longitudinally. Established CMR measures with additional newly developped, promising, highly refined and clinically…
- Conditions
- Aortic Valve Disease, Pulmonary Valve Disease, Child, Only, Magnetic Resonance Imaging
- Trial name
- AI-CMR (NCT05979870)
- Testing
- Valvuloplasty,
- Where
- Sweden
- Volunteers
- 45 people
- Sponsor
- Sahlgrenska University Hospital
Gastrointestinal Malignancies
A Study of the Role of Circulating Tumor DNA in Predicting the Likelihood of Organ Preservation After Clinical Complete Response to Neoadjuvant Therapy for Rectal Cancer
In this research study, the investigators are looking to see if the circulating tumor DNA (genetic material), also known as ctDNA, in the blood will help them predict whether the participant's cancer will come back.
- Trial name
- NCT03749083
- Testing
- The Functional Assessment of Cancer Therapy- Colorectal
- Where
- 4 sites in United States
- Sponsor
- Massachusetts General Hospital
Focal Epilepsy, Temporal Lobe Epilepsy
Spatial Scene Recognition Memory in Epilepsy Surgery
This study investigates the anatomical and physiological basis of spatial scene recognition memory in patients with temporal lobe epilepsy and temporal lobe lesions.
- Conditions
- Focal Epilepsy, Temporal Lobe Epilepsy, Medically Refractory Epilepsy, Memory Disorders
- Trial name
- NCT07580183
- Testing
- Virtual Tour Recognition Memory Task, Intracranial EEG Recording with Research Electrodes (Aim III only), MRI Neuroimaging and Neuropsychological Assessment (Aim I)
- Where
- 2 sites in United States
- Volunteers
- 620 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Arthroplasty, Replacement, Hip, Exercise Therapy
Walking Skill Training Program Effects in Patients With Total Hip Arthroplasty
Rehabilitation plays an important part after total hip arthroplasty. In this common practice few studies have been performed on this issue. The aims of this study were: 1.
- Trial name
- NCT00808483
- Testing
- Walking skill training program
- Where
- Norway
- Volunteers
- 68 people
- Sponsor
- University of Oslo
Violent Traumatic Event Having Been in an Earthquake (History)
Acceptance-commitment Therapy-based Psychoeducation for Individuals Experiencing Earthquakes
This research aims to reduce the stress level of individuals within the scope of acceptance and determination-based psychoeducation, to increase the individual's positive expectations for the future, to increase the sense of…
- Trial name
- NCT06536205
- Testing
- psychoeducation
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Mustafa Kemal University
Psoriasis
Comparison Study of Psoriasis Severity Assessment Tools
This study evaluates the performance of objective psoriasis severity assessment tool compared with a subjective assessment tool for the assessment of the improvement of psoriasis after oral cyclosporine A or methotrexate…
- Trial name
- NCT02655705
- Testing
- Cyclosporine A, Methotrexate
- Where
- South Korea
- Volunteers
- 34 people
- Sponsor
- Seoul National University Hospital
Women Diagnosed With Cancer, Egg Donors
Oocyte Cryopreservation by Slow Freezing and Vitrification
This study seeks to evaluate whether the vitrification technique, as compared to the more traditional slow-cooling technique, leads to higher rates of successful thawing, fertilization, implantation and delivery.
- Conditions
- Women Diagnosed With Cancer, Egg Donors, Single Women, Failed Sperm Procurement in IVF
- Trial name
- NCT01223105
- Testing
- slow freeze, Vitrification
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Reproductive Medicine Associates of New Jersey
Polycystic Ovary Syndrome
Polycystic Ovary Syndrome (PCOS) - Effect Of Physical Exercise And Electroacupuncture
Hypothesis: The overall hypothesis is that women with PCOS, both obese and non-obese, have larger adipocytes, altered metabolism and signs of inflammation in adipose tissue and that these changes are associated with high…
- Trial name
- PCOSNTS (NCT00484705)
- Testing
- Electroacupuncture, Physical exercise, Untreated control
- Where
- Sweden
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Göteborg University
Metabolic Syndrome
Resistance Training and Cardiometabolic Risk
Little is known on the effects of resistance training (RT) alone in individuals with metabolically healthy obesity (MHO) and metabolically unhealthy obesity (MUHO).
- Trial name
- NCT06054594
- Testing
- Resistance exercise
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Université du Québec a Montréal
Therapeutic Plasma Exchange
IMPACT OF THERAPEUTIC PLASMA EXCHANGE ON ACQUIRED VACCINAL ANTI-SARS-CoV-2 ANTIBODIES.
Context: Therapeutic plasma exchange is an extracorporeal blood purification technique that removes pathogenic substances (including antibodies) from plasma. This technique also combines an immunomodulatory effect.
- Trial name
- NCT05191394
- Testing
- Evolution of antibodies titre
- Where
- Belgium
- Volunteers
- 15 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Non-cardiac Chest Pain, Cardiac Anxiety
iCBT for Cardiac Anxiety in Patients With NCCP
Non-cardiac chest pain (NCCP) is a common condition that significantly affects patients' mental well-being, overall quality of life, and healthcare use.
- Trial name
- IKSIT2 (NCT06136494)
- Testing
- Internet-delivered cognitive behavioural therapy, Attention control
- Where
- Sweden
- Volunteers
- 126 people
- Sponsor
- Linkoeping University
Frailty, Pre-operative Exercise
Home-based Exercise for Frail Individuals Prior to Cardiac Surgery
The goal of this quasi-experimental feasibility study is to determine if a home based exercise program, that is supported virtually by a physiotherapist, is feasible for frail adults that are waiting for cardiac surgery.
- Conditions
- Frailty, Pre-operative Exercise, Prehabilitation, Cardiac Surgery
- Trial name
- NCT05834556
- Testing
- Prehabilitation
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Dr. Todd A Duhamel
Episodic Migraine Headache
A Multicenter Assessment of LBR-101 in High Frequency Episodic Migraine
The purpose of this study is to determine whether monthly subcutaneous administration of LBR-101 (fremanezumab) is safe and provides migraine prevention in subjects with high frequency episodic migraine.
- Trial name
- NCT02025556
- Testing
- LBR-101 High Dose, LBR-101 Low Dose
- Where
- 63 sites in United States
- Volunteers
- 297 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Myofeedback, Hemiplegia
Effect of Myofeedback and Neuromuscular Electrical Stimulation on Hemiplegic Children After Brain Tumor Resection
This study was conducted to compare between the effect of neuromuscular electrical stimulation and myofeedback on upper limb function, muscle activity and brain derived neurotropic factor in blood for children with hemiplegia…
- Conditions
- Myofeedback, Hemiplegia, Child, Only
- Trial name
- NCT07606222
- Testing
- selected physical therapy program, biofeedback, neuromuscular electric stimulation
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Cairo University
Congenital Heart Disease
Online Support 4 CHD Kids & Caregivers
This study will evaluate a virtual mental health parenting stepped-care intervention (I-InTERACT-North) to determine if the program works to improve positive parenting skills and child behaviour among families with children born…
- Trial name
- NCT06075251
- Testing
- I-InTERACT-North
- Where
- Canada
- Volunteers
- 382 people
- Sponsor
- The Hospital for Sick Children
Persistent Spinal Pain Syndrome Type 2 (PSPS-T2), Lower Spine, Spinal Cord Sensitivity to Neurostimulation
Neurophysiological Effects of Medication Tapering During Treatment With Spinal Cord Stimulation
This study is being conducted in patients who will receive a spinal cord stimulator. This device helps manage chronic neuropathic pain in the trunk and/or limbs.
- Conditions
- Persistent Spinal Pain Syndrome Type 2 (PSPS-T2), Lower Spine, Spinal Cord Sensitivity to Neurostimulation, Neurophysiological Sensitivity to Spinal Cord Stimulation
- Trial name
- NCT07413731
- Testing
- Spinal Cord Stimulation with Evoke Closed-Loop System
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- Brai²n
Hematopoietic and Lymphoid Cell Neoplasm
Exercise Prehab in Older Adults With Hematologic Malignancies
This pilot trial studies a structured exercise program intervention in improving physical activity in older patients with hematologic malignancies undergoing cancer therapy.
- Trial name
- NCT02791737
- Testing
- Exercise Intervention, Laboratory Biomarker Analysis, Physical Therapy
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
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