Clinical trials: Prednisolone, completed
Post-surgical Cystoid Macular Edema (PSCME)
Treatment of Post-surgical Cystoid Macular Edema With Topical Steroids Trial (TEMPEST-1)
The purpose of this study is to compare the change in visual acuity of patients with post surgical cystoid macular edema who will be treated with two different regimens.
- Trial name
- TEMPEST (NCT01769352)
- Testing
- PredA + Kelac
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Johns Hopkins University
Renal Failure, End Stage
The ONE Study ATDC Trial
To collect evidence of the safety of administering autologous tolerogenic dendritic cells (ATDC) preparations to living-donor renal transplant recipients in the context of an international European Union funded consortium aimed…
- Trial name
- ONEatDC (NCT02252055)
- Testing
- ATDC_Nantes
- Where
- France
- Volunteers
- 11 people
- Sponsor
- Nantes University Hospital
Covid19
Impact of Steroids on Inflammatory Response in Covid-19
we designed this study to observe the efficacy and safety of dexamethasone versus methylprednisolone in covid-19 diseased patients upon monitoring the inflammatory response and to compare the outcome when these steroids will be…
- Trial name
- NCT04909918
- Testing
- Dexamethasone, Methylprednisolone
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
COVID-19 Pulmonary Complications
Corticosteroid Therapy in Pulmonary Sequelae of Covid-19
Introduction: The new coronavirus (SARS-CoV-2) is a virus with an intense capacity for dissemination and high mortality rate. The main cause of death is viral pneumonia, characterized as organizing pneumonia that responds to…
- Trial name
- COPOSTCOVID (NCT07380152)
- Testing
- Prednisolone
- Where
- Brazil
- Volunteers
- 100 people
- Sponsor
- University of Sao Paulo
Frozen Shoulder
Oral Corticosteroids Versus Exercises On Treatment Of Frozen Shoulder,
The purpose of this study is to compare the efficacy of exercise and oral corticosteroids the treatment of a FS.
- Trial name
- NCT05212740
- Testing
- Corticosteroid, Exercise
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 33 people
- Sponsor
- Istanbul University
Frozen Shoulder
Therapeutic Effect of Shoulder Anterior Capsular Block Versus Suprascapular Nerve Block in Patients With Frozen Shoulder
he study will include 50 patients with frozen shoulder with no healthy volunteer , Patients in this study will be randomized into two groups suprascapular nerve block and Shoulder anterior capsular block
- Trial name
- NCT06725823
- Testing
- suprascapular nerve block group, shoulder anterior capsular block group
- Where
- Egypt
- Volunteers
- 54 people
- Sponsor
- Sohag University
Juvenile Dermatomyositis
Five-year Actively Controlled Clinical Trial in New Onset Juvenile Dermatomyositis
This is a 5-year project, involving 185 partners from 46 countries ((110 in 21 European Union (EU) States and 75 in 25 extra-EU States)), with a randomised clinical trials (RCT) in juvenile dermatomyositis (JDM): 5-year phase III…
- Trial name
- PRINTOJDMTR (NCT00323960)
- Testing
- 3 MPDN pulse + PDN, 3 MPDN pulse + PDN + CSA, 3 MPDN pulse + PDN + MTX
- Where
- Italy
- Volunteers
- 139 people
- Sponsor
- Istituto Giannina Gaslini
Migraine Headache
Greater Occipital Nerve Block for Migraine Prophylaxis
Migraine is a common neurological condition that can be disabling, particularly if chronic. Greater occipital nerve (GON) block has been utilized for decades for the treatment of migraine in the absence of a single randomized…
- Trial name
- NCT00915473
- Testing
- bupivicaine, normal saline, methylprednisolone
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Mayo Clinic
Acute Respiratory Distress Syndrome, Acute Lung Injury
Early Low Dose Steroid Therapy of Acute Respiratory Distress Syndrome
The purpose of this study is to determine whether the 2mg/kg administration of corticosteroids, in the form of methylprednisolone sodium succinate, in early phase acute respiratory distress syndrome after thoracic surgery, will…
- Conditions
- Acute Respiratory Distress Syndrome, Acute Lung Injury, Postoperative Complications
- Trial name
- NCT00290602
- Testing
- Methylprednisolone sodium succinate
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- National Cancer Center, Korea
Prostate Cancer
A Study of Abiraterone Acetate (JNJ-212082) and Prednisolone in Patients With Advanced Prostate Cancer
The purpose of this study is to assess the safety and efficacy in Korea or Taiwan of oral abiraterone acetate and oral prednisolone in men with metastatic-castration resistant prostate cancer (mCRPC) and with disease progression…
- Trial name
- NCT01685983
- Testing
- Abiraterone acetate, Prednisolone
- Where
- 8 sites in South Korea, Taiwan
- Volunteers
- 82 people
- Sponsor
- Janssen Research & Development, LLC
Children Receiving Prednisone or Prednisolone or Methylprednisolone or Hydrocortisone
Pharmacokinetics of Glucocorticoids in Children (GLUCOPED)
The purpose of this study is to determine individual susceptibility factors (drug interactions, genetic factors such as enzyme polymorphism…) to explain wide interindividual variability towards corticosteroids (prednisone…
- Trial name
- GLUCOPED (NCT02252237)
- Testing
- Pharmacokinetic
- Where
- France
- Volunteers
- 146 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Asthma in Children
Early Administration of Steroids in the Ambulance Setting
Asthma is the most common chronic disease of childhood and is a leading cause of emergency medical treatment. For children experiencing an asthma exacerbation, emergency department (ED) guidelines recommend early systemic…
- Trial name
- EASI-AS-ODT (NCT03962894)
- Testing
- Prednisolone
- Where
- 7 sites in United States
- Volunteers
- 834 people
- Sponsor
- University of Florida
Acute Lymphoblastic Leukemia
Total Therapy Study XVI for Newly Diagnosed Patients With Acute Lymphoblastic Leukemia
The primary objective of this study (TOTXVI) is to compare the clinical benefit, the pharmacokinetics, and the pharmacodynamics of polyethylene glycol-conjugated (PEG) asparaginase given in higher dose (HD PEG) versus those of…
- Trial name
- NCT00549848
- Testing
- Prednisone, Vincristine, Daunorubicin, PEG-L-asparaginase, Erwinia L-asparaginase, Doxorubicin, Cyclophosphamide, Cytarabine, Thioguanine, Clofarabine, Methotrexate, Mercaptopurine, Dexamethasone, Etoposide, Dasatinib
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- St. Jude Children's Research Hospital
Liver Transplantation, Infection
Efficacy and Safety of Basiliximab, Cyclosporine/Cyclosporine Microemulsion, and Steroids in Pediatric de Novo Liver Transplant Recipients Avoiding Intraoperative Steroids
Systemic infection is still a major concern in young children with liver transplantation. The approach of this study is to reduce the risk of systemic infections by avoiding intraoperative steroids (another class of…
- Trial name
- NCT00149890
- Testing
- Basiliximab, Cyclosporine/cyclosporine microemulsion, Steroid
- Where
- Germany
- Volunteers
- 77 people
- Sponsor
- Novartis
Healthy Participants
Pharmacokinetic Interaction Trial of Clofutriben With Midazolam and Prednisolone
Drug: 2 single oral doses of midazolam, 2 single oral doses of prednisolone , and clofutriben once daily for 16 days.
- Trial name
- DDI (NCT07226635)
- Testing
- midazolam, clofutriben once daily for 16 days, 2 single oral doses of prednisolone
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Sparrow Pharmaceuticals
Kaposiform Hemangioendothelioma, Kasabach Merritt Phenomenon
Sirolimus Versus Sirolimus Plus Prednisolone for Kaposiform Hemangioendothelioma
Kaposiform hemangioendothelioma (KHE) is a rare vascular neoplasm that occurs predominantly in infancy or early childhood. KHE has a nearly equal sex ratio.
- Trial name
- NCT03188068
- Testing
- Sirolimus, Prednisolone
- Where
- China
- Volunteers
- 30 people
- Sponsor
- West China Hospital
Diabetes Mellitus, Type 1, Adrenal Insufficiency
Hypoglycaemia (Low Blood Sugar) in Adults With Diabetes and Adrenal Failure
The purpose of this study is to measure how often low blood sugars occur in people who live with both adrenal insufficiency (AI) and diabetes and need to take insulin.
- Conditions
- Diabetes Mellitus, Type 1, Adrenal Insufficiency, Diabetes Mellitus Type 2 - Insulin-Treated
- Trial name
- HYPO-DIAD (NCT05806190)
- Testing
- Continuous Glucose Monitoring
- Where
- United Kingdom
- Volunteers
- 32 people
- Sponsor
- Imperial College Healthcare NHS Trust
Leukemia, Multiple Myeloma and Plasma Cell Neoplasm
Donor Bone Marrow Transplantation in Treating Patients With Hematologic Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Bone marrow transplantation may allow the doctor to give higher doses of chemotherapy drugs and kill more…
- Conditions
- Leukemia, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes
- Trial name
- NCT00003960
- Testing
- busulfan, cyclophosphamide, methylprednisolone
- Where
- 2 sites in United States
- Volunteers
- 36 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Disorder Related to Renal Transplantation, Effects of Immunosuppressant Therapy
Prospective Donor Specific T Response Measurment for IS Minimization in de Novo Renal Transplantation
The main objective of the study is to demonstrate the utility and safety of the IFN-γ (Interferon Gamma) ELISPOT (Enzyme-linked immunosorbent spot) marker for the stratification of kidney transplant recipients into low and high…
- Trial name
- NCT02540395
- Testing
- Tacrolimus (for Group B), MMF (mycophenolate mofetil) (for Group B), 6-methyl prednisolone (Steroids) (for Group B)
- Where
- 8 sites in Czechia, France and 4 more
- Volunteers
- 184 people
- Sponsor
- Prof. Dr. Petra Reinke
Prostate Cancer Metastatic
Early Access to Cabazitaxel in Patients With Metastatic Hormone Refractory Prostate Cancer Previously Treated With a Docetaxel-containing Regimen
The purpose of this study is to allow patients similar to that evaluated in the TROPIC trial (NCT00417079), and Investigators access to cabazitaxel for the management of metastatic Hormone Refractory Prostate Cancer (mHRPC) in…
- Trial name
- NCT01254279
- Testing
- CABAZITAXEL
- Where
- 165 sites in Australia, Austria and 27 more
- Volunteers
- 984 people
- Sponsor
- Sanofi
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