Clinical trials: Prednisolone, completed
Low Back Pain, Sacroiliac Joint Synovitis
Treatment for Sacroiliac Joint Pain Using Platelet-rich Plasma (PRP) Versus Steroid/Anesthetic
The purpose of this study is to determine if platelet-rich plasma is superior to steroid/anesthetic for the treatment of sacroiliac joint pain.
- Trial name
- NCT05121961
- Testing
- Sacroiliac intra-articular injection
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- University of Utah
Postherpetic Neuralgia
Ultrasound-Guided Thoracic Paravertebral Block With Steroid and Local Anesthetic for Acute Herpes Zoster: Effects on Pain Control and Prevention of Postherpetic Neuralgia
Background: Acute herpes zoster causes severe neuropathic pain and may progress to postherpetic neuralgia (PHN). This study aims to evaluate ultrasound-guided thoracic paravertebral block with local anesthetic and steroid in…
- Trial name
- NCT07349680
- Testing
- Valacyclovir + Paracetamol (Acetaminophen) + Gabapentin (standard medical therapy), Ultrasound-guided thoracic paravertebral block (TPVB) with bupivacaine 0.25% + methylprednisolone 40 mg
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assiut University
Hip Arthropathy
Periarticular Injection Versus Peripheral Nerve Block in Total Hip Arthroplasty
This study will assess if preoperative quadratus lumborum block (QLB)/lateral femoral cutaneous nerve block (LFCNB) with ropivacaine and glucocorticoids provide more effective analgesia than periarticular injection (PAI) with the…
- Trial name
- NCT03977454
- Testing
- Nerve Block, Periarticular Injection (PAI), Ropivacaine
- Where
- United States
- Volunteers
- 192 people
- Sponsor
- Yale University
Lupus Erythematosus, Systemic
Synergetic B-cell Immunomodulation in SLE - 2nd Study.
In follow-up of the previous SynBioSe Study the present study is a randomized controlled trial designed to further investigate the long-term clinical and imunological efficacy of combination B-cell targeting by starting treatment…
- Trial name
- SynBioSe-2 (NCT03747159)
- Testing
- Belimumab Injection
- Where
- 4 sites in Netherlands
- Volunteers
- 71 people
- Sponsor
- Leiden University Medical Center
Heart Transplantation
A Study Investigating the Renal Tolerability, Efficacy, and Safety of a CNI-free Versus a Standard Regimen in de Novo Heart Transplant (HTx) Recipients
This study will assess whether a calcineurin inhibitor (CNI)-free regimen with everolimus and mycophenolic acid is associated with a better renal outcome as compared to the standard regimen containing cyclosporine A (which…
- Trial name
- MANDELA (NCT00862979)
- Testing
- Everolimus (EVR), cyclosporine A (CyA), tacrolimus (TAC)
- Where
- 9 sites in Germany
- Volunteers
- 162 people
- Sponsor
- Novartis Pharmaceuticals
Nephrotic Syndrome
Prednisolone Trial in Children Younger Than 4 Years
This study is a multicentric, randomized, parallel group, open label controlled trial of children age 1 year up to 4 years with new onset, idiopathic nephrotic syndrome.
- Trial name
- NCT03141970
- Testing
- Prednisolone
- Where
- 5 sites in United States, India
- Volunteers
- 170 people
- Sponsor
- All India Institute of Medical Sciences
Intraocular Inflammation
A Comparison of 0.5% Loteprednol Etabonate Versus 1% Prednisolone Acetate Following Cataract Surgery
Patients are routinely given steroid eye drops following cataract surgery. This study will compare 2 approved drops:Loteprednol Etabonate versus Prednisolone Acetate Eye drops used following cataract surgery.
- Trial name
- NCT01384266
- Where
- 2 sites in United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Associated Eye Care, Minnesota
Optic Neuritis
Optic Neuritis Recovery After Oral or IV Corticosteroids
Patients aged 18-65 with acute demyelinating optic neuritis where treatment with high dose corticosteroids are already been chosen by the patient and the diagnosing physician will be contacted for screening and enrollment.
- Trial name
- NCT01524250
- Testing
- corticosteroids
- Where
- 2 sites in Canada
- Volunteers
- 51 people
- Sponsor
- London Health Sciences Centre
High Risk Localised Prostate Carcinoma
Neo-adjuvant Abiraterone Prostate Study
The role of this study is to focus on the potential role of abiraterone acetate in treatment-naive patients newly diagnosed with high-risk localised prostate cancer requiring combined hormonal therapy and radiotherapy.
- Trial name
- NCT02160353
- Testing
- Abiraterone acetate, Prednisolone
- Where
- 3 sites in Ireland
- Volunteers
- 45 people
- Sponsor
- Cancer Trials Ireland
Upper Respiratory Tract Infection, Asthma
Reducing the Acute Care Burden of Childhood Asthma on Health Services in British Columbia
The purpose of this study is to investigate the benefits of giving filled prescription of a medication to be used upon early onset of symptoms of URTI induced asthma.
- Trial name
- NCT01326494
- Testing
- Arm 1 Oral Cortico Steroids
- Where
- Canada
- Volunteers
- 92 people
- Sponsor
- University of British Columbia
Evidence of Liver Transplantation, Rejection
Safety and Efficacy of Alemtuzumab in Pediatric Intestinal Transplantation
This open-label clinical trial will evaluate the safety and efficacy of Alemtuzumab (Campath, Bayer Corp., Pittsburgh) in children (0-17) and adults (18-25) receiving intestinal transplant.
- Conditions
- Evidence of Liver Transplantation, Rejection, ALEMTUZUMAB
- Trial name
- NCT01208337
- Testing
- Alemtuzumab
- Volunteers
- 23 people
- Sponsor
- University of Pittsburgh
Lymphoblastic Lymphoma
NHL16: Study For Newly Diagnosed Patients With Acute Lymphoblastic Lymphoma
This is a phase II clinical trial using risk-adapted therapy. The treatment is acute lymphoblastic leukemia (ALL)-based therapy, using multi-agent regimens comprising of induction, consolidation, and continuation (maintenance)…
- Trial name
- NCT01451515
- Testing
- Prednisone, Vincristine, Daunorubicin
- Where
- 2 sites in United States
- Volunteers
- 23 people
- Sponsor
- St. Jude Children's Research Hospital
Colorectal Cancer, Head and Neck Cancer
Skin Rash Study Before Chemotherapy in Colorectal & Head and Neck Cancer Patients
The purpose of this study is to determine if using preventive treatments such as Doxycycline (an anti-biotic) capsules, sunscreen with SPF 30, Hydrocortisone 1% cream and a moisturizer will help to reduce the incidence and…
- Trial name
- NCT01874860
- Testing
- Doxycycline, Hydrocortisone 1% cream, Sunscreen
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Louisville
Covid19, COVID-19 Pneumonia
Systemic Corticosteroids in Treatment of Post-COVID-19 Interstitial Lung Disease
Aim: To investigate the efficacy of systemic corticosteroids in treatment for Post-COVID-19 Interstitial Lung Disease. Method: Method: In this multi-centre, prospective, randomised controlled open label clinical trial, patients…
- Conditions
- Covid19, COVID-19 Pneumonia, Interstitial Lung Disease
- Trial name
- STERCOV-ILD (NCT04988282)
- Testing
- Methylprednisolone Tablet
- Where
- Turkey (Türkiye)
- Volunteers
- 262 people
- Sponsor
- Turkish Thoracic Society
Pudendal Neuralgia, Canal Syndrome
Therapeutic Effects Analysis of Pudendal Nerve Infiltrations After 3 Months, in Patients Suffering of Pudendal Neuralgia
Pudendal neuralgia is a recent identified pathology, extremely invalidating, related to chronic pelvic entrapment. Nowadays, pudendal neuralgia can be treated with: neuropathic pains treatment specific kinesitherapy Alcock's…
- Trial name
- INFILTHERA (NCT00851513)
- Testing
- Lidocaine, Depmedrol, physiological serum
- Where
- 9 sites in France
- Volunteers
- 202 people
- Sponsor
- Nantes University Hospital
Castration-Resistant Prostatic Neoplasms
A Study of Cetrelimab (JNJ-63723283), a Programmed Cell Death Receptor-1 (PD-1) Inhibitor, Administered in Combination With Apalutamide in Participants With Metastatic Castration-Resistant Prostate Cancer
The purpose of this study is to evaluate the safety of the combination of cetrelimab, with apalutamide and to define a population of participants with metastatic castration-resistant prostate cancer (mCRPC) who respond to…
- Trial name
- NCT03551782
- Testing
- Cetrelimab 480 mg, Apalutamide 240 mg
- Where
- 34 sites in United States, Belgium and 5 more
- Volunteers
- 33 people
- Sponsor
- Janssen Research & Development, LLC
Disorder Related to Renal Transplantation, Effects of Immunosuppressant Therapy
Prospective Donor Specific T Response Measurment for IS Minimization in de Novo Renal Transplantation
The main objective of the study is to demonstrate the utility and safety of the IFN-γ (Interferon Gamma) ELISPOT (Enzyme-linked immunosorbent spot) marker for the stratification of kidney transplant recipients into low and high…
- Trial name
- NCT02540395
- Testing
- Tacrolimus (for Group B), MMF (mycophenolate mofetil) (for Group B), 6-methyl prednisolone (Steroids) (for Group B)
- Where
- 8 sites in Czechia, France and 4 more
- Volunteers
- 184 people
- Sponsor
- Prof. Dr. Petra Reinke
Graft Versus Host Disease
Phase II Trial of Natalizumab + Prednisone for Initial Therapy of Acute GI GVHD
This research study is a Phase II clinical trial, which tests the safety and effectiveness of an investigational drug Natalizumab in treating Acute Graft-Versus-Host Disease (GVHD) in the Gastrointestinal (GI) Tract.
- Trial name
- NCT02176031
- Testing
- Natalizumab, Methylprednisolone
- Where
- 2 sites in United States
- Volunteers
- 21 people
- Sponsor
- Dana-Farber Cancer Institute
Shoulder Arthritis
Quality of Life and Pain With Infiltration or Suprascapular Nerve Block in Glenohumeral Arthirtis
Efficacy in pain and health related quality of life of suprascapular nerve block ultrasound guided and glenohumeral infiltration in glenohumeral arthritis
- Trial name
- NCT03794505
- Testing
- Methylprednisolone Acetate, Lidocaine 2% Injectable Solution, Ropivacaine HCl Inj 7.5 MG/ML
- Where
- Mexico
- Volunteers
- 40 people
- Sponsor
- Instituto Mexicano del Seguro Social
Meniere's Disease
Transtympanic Gentamicin vs. Steroids in Refractory Meniere's Disease
This trial aims to compare transtympanic steroids against the standard treatment (transtympanic gentamicin) in refractory unilateral Meniere's disease.
- Trial name
- NCT00802529
- Testing
- Methylprednisolone, Gentamicin
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- Imperial College London
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