Clinical trials: Prednisolone, completed
Prostate Cancer Metastatic
Evaluation of Safety of Cabazitaxel (Jevtana) in Patients With Metastatic Hormone Refractory Prostate Cancer
Primary Objective: To evaluate the safety of cabazitaxel (Jevtana) in patients with metastatic hormone refractory prostate cancer Secondary Objectives: 1.
- Trial name
- NCT02074137
- Testing
- CABAZITAXEL XRP6258, Prednisone, Prednisolone
- Where
- 3 sites in India
- Volunteers
- 10 people
- Sponsor
- Sanofi
Dermatitis, Atopic
Efficacy and Safety Study of Advantan for Maintenance Treatment of Atopic Dermatitis
Purpose of the study: One bothering feature of atopic dermatitis is its relapsing nature. Hence, it is worthwhile to test modes how to efficiently prevent relapses or at least increase the time until the disease recurs.
- Trial name
- NCT00185510
- Testing
- Methylprednisolone Aceponate (Advantan, BAY86-4862)
- Volunteers
- 250 people
- Sponsor
- LEO Pharma
Graves Ophthalmopathy
Comparison of the Effectiveness of Two Glucocorticoid Regimens for Treatment of Graves' Orbitopathy
The goal of this interventional study is to compare the effectiveness of two different glucocorticoid regimens for treatment of active moderate-to-severe Graves' orbitopathy. The main questions it aims to answer are: 1.
- Trial name
- NCT05793359
- Testing
- Methylprednisolone
- Where
- Bulgaria
- Volunteers
- 62 people
- Sponsor
- Medical University of Sofia
Scleral Buckling
The Effect of Glaucoma Drops on of the Duration of a Pure Intraocular Gas Bubble
A controlled clinical study comparing the effect of topical aqueous suppressants on intraocular gas duration.
- Trial name
- NCT01843920
- Testing
- Timolol-dorzolamide (Glaucoma drops), standard post-operative topical drops
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Jason Hsu, MD
Renal Transplantation
Efficacy and Safety of Enteric-coated Mycophenolate Sodium and Cyclosporine in Combination With and Without Steroids, in Adult Renal Transplant Recipients
This study will investigate the efficacy and safety of a steroid avoidance regimen in comparison with steroid treatment in combination with an initially higher dose of enteric-coated mycophenolate sodium (EC-MPS) and cyclosporine…
- Trial name
- NCT00413920
- Testing
- Enteric-coated mycophenolate sodium (EC-MPS), Prednisone
- Where
- France
- Volunteers
- 222 people
- Sponsor
- Novartis
Habitual Abortion, Recurrent Pregnancy Loss
Intravenous Immunoglobulin and Prednisolone for RPL After ART.
Recurrent pregnancy loss (RPL) affects around 5 % of women in reproductive age. The underlying cause of RPL is most often unknown, probably multifactorial, and no treatment with documented effect on chance of live birth exists.
- Conditions
- Habitual Abortion, Recurrent Pregnancy Loss, Fertility Disorders, Miscarriage
- Trial name
- RPL (NCT04701034)
- Testing
- Human Intravenous Immunoglobulins, (Privigen (R), CLS Behring), Prednisolone Tablets, Human Albumin Solution
- Where
- Denmark
- Volunteers
- 80 people
- Sponsor
- Aalborg University Hospital
B-Cell Chronic Lymphocytic Leukemia
Rituximab in Pretreated Elderly or Unfit B-CLL Patients
The study will test the efficacy rituximab in addition to glucocorticoids for the treatment of B-CLL in elderly or unfit patients.
- Trial name
- NCT01576588
- Testing
- Rituximab, Glucocorticoid
- Where
- Lithuania
- Volunteers
- 25 people
- Sponsor
- Prof. Dr. Med. Laimonas Griskevicius
Graft Versus Host Disease, Leukemia
Chemotherapy, Radiation Therapy, and Umbilical Cord Blood Transplantation in Treating Patients With Hematologic Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage cancer cells.
- Conditions
- Graft Versus Host Disease, Leukemia, Lymphoma, Myelodysplastic Syndromes
- Trial name
- NCT00003661
- Testing
- anti-thymocyte globulin, busulfan, cyclosporine
- Where
- 17 sites in United States
- Volunteers
- 3 people
- Sponsor
- Roswell Park Cancer Institute
Hepatocellular Carcinoma
Immunosuppression in Patients Undergoing Liver Transplantation for Hepatocellular Carcinoma
The purpose of this study is to determine the safety and efficacy of sirolimus-based immunosuppressive therapy in patients following orthotopic liver transplantation (OLT) for hepatocellular carcinoma (HCC), with regard to HCC…
- Trial name
- NCT00355862
- Testing
- CNI, MMF, Steroids, Aza etc. (mTOR inhibitor free), Sirolimus
- Where
- Germany
- Volunteers
- 525 people
- Sponsor
- University of Regensburg
Polymyalgia Rheumatica
Induction and Tapering Therapy With Tofacitinib and Glucocorticoid in Patients With Polymyalgia Rheumatica
This will be efficacy and safety of Induction and Tapering Therapy with Tofacitinib and Glucocorticoid in patients with Polymyalgia Rheumatica (ITTG PMR): An open-label 52-week randomized controlled trial
- Trial name
- ITTGPMR (NCT06172361)
- Testing
- Prednisone+Tofacitinib, Prednisone
- Where
- China
- Volunteers
- 104 people
- Sponsor
- Zhejiang University
Kawasaki Disease
Different Doses of IVIG for Kawasaki Disease
The objective of this study is to investigate the effect of different doses of intravenous immunoglobulin (IVIG) (1g/kg once, 1g/kg twice, 2g/kg once) for Kawasaki disease (KD) in a multicentre, prospective,randomised trial.
- Trial name
- NCT02439996
- Testing
- IVIG (1g/kg,once), IVIG (1g/kg,twice), IVIG (2g/kg.once)
- Where
- China
- Volunteers
- 404 people
- Sponsor
- Children's Hospital of Fudan University
Alopecia Totalis, Alopecia Universalis
Safety and Efficacy of Oral Mega Pulse Methylprednisolone in Severe Therapy Resistant Alopecia Areata
Systemic Pulse Glucocorticoids have been shown to be effective in widespread Alopecia areata but not the totalis, universalis or ophiasic type.
- Conditions
- Alopecia Totalis, Alopecia Universalis, Ophiasic Alopecia
- Trial name
- NCT01167946
- Testing
- methylprednisolone sodium succinate
- Where
- Saudi Arabia
- Volunteers
- 42 people
- Sponsor
- King Saud University
Chronic Pain, Back Pain
Tracking Outcomes in Pain Patients Using Fitness Devices
The investigators are assessing the validity of fitness devices as surrogate measures of chronic pain survey outcomes.
- Trial name
- NCT02420457
- Testing
- Epidural injection, Epidural steroid injection as determined by routine care provider
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of North Carolina, Chapel Hill
Biological Availability
A Study Comparing Drug Availability Of Methylprednisolone In Liquid Form Versus Methylprednisolone In Tablet Form
A new formulation of methylprednisolone is being developed. A study is needed to determine the drug availability using the new formulation, a powder for reconstitution into a suspension, versus the current commercially available…
- Trial name
- NCT01267201
- Testing
- methylprednisolone
- Where
- Singapore
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Pfizer
HIV Disease Progression
Progression of HIV-Disease Under Low Dose Corticosteroids
There has been reports that low dose prednisolone stabilizes CD4-counts in HIV infected individuals. However, until now, there are no prospective randomized studies on the use of corticosteroids in latent HIV disease.
- Trial name
- ProCort1 (NCT01299948)
- Testing
- Prednisolone
- Where
- Tanzania
- Volunteers
- 326 people
- Sponsor
- Medical Mission Institute, Germany
Systemic Lupus Erythematosus, SLE
Gradual Withdrawal of Low-dose Glucocorticoid in Clinically Quiescent Systemic Lupus Erythematosus.
This study aims compare the flare rate of maintenance versus gradual withdrawal of 5 mg/day prednisone in systemic lupus erythematosus (SLE) patients with clinically quiescent disease.
- Trial name
- NCT06234852
- Testing
- Glucocorticoid withdrawal group, Glucocorticoid maintenance group
- Where
- Thailand
- Volunteers
- 20 people
- Sponsor
- Phramongkutklao College of Medicine and Hospital
Diabetes Mellitus, Steroid Diabetes
Sitagliptin Prophylaxis for Glucocorticoid-Induced Impairment of Glucose Metabolism in Males With the Metabolic Syndrome
The investigators will assess whether the DPP-inhibitor sitagliptin will ameliorate glucocorticoid-induced impairment of glucose metabolism and beta-cell dysfunction and thus could be used as a prophylaxis for…
- Conditions
- Diabetes Mellitus, Steroid Diabetes, Glucocorticoid-induced Diabetes, Beta-cell Function
- Trial name
- SPHINX (NCT00721552)
- Testing
- Sitagliptin 100 mg, Prednisolone 30 mg
- Where
- Netherlands
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Amsterdam UMC, location VUmc
Leukemia
Nilotinib and Combination Chemotherapy in Treating Patients With Newly Diagnosed Acute Lymphoblastic Leukemia
RATIONALE: Nilotinib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy work in different ways to stop the growth of cancer cells, either by killing the cells or…
- Trial name
- NCT00844298
- Testing
- Nilotinib+mVPD
- Where
- 16 sites in South Korea
- Volunteers
- 91 people
- Sponsor
- Asan Medical Center
Endoscopic Sinus Surgery
The Role of the Submucosal Conchoplasty Technique in Improving the Postoperative Middle Meatus Outcome After ESS
The study aimed to compare the applicability of the classic lateral lamellectomy versus the submucosal conchoplasty techniques in managing the concha bullosa during and after ESS.
- Trial name
- NCT05930132
- Testing
- submucosal conchoplasty, classic lateral lamellectomy
- Where
- Egypt
- Volunteers
- 56 people
- Sponsor
- Kafrelsheikh University
Leukemia
Hyper-CVAD With Liposomal Vincristine in Acute Lymphoblastic Leukemia
Any time the words "you," "your," "I," or "me" appear, it is meant to apply to the potential participant. The goal of this clinical research study is to learn if intensive chemotherapy (hyper-CVAD therapy) given in combination…
- Trial name
- NCT01319981
- Testing
- Rituximab, Imatinib, Cyclophosphamide
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- M.D. Anderson Cancer Center
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