Clinical trials: Prednisolone, completed
Rheumatoid Arthritis
A Study of MabThera/Rituxan (Rituximab) in Combination With Methotrexate in Patients With Rheumatoid Arthritis and Inadequate Response to DMARD Therapy
This study will evaluate the efficacy and safety of MabThera/Rituxan plus methotrexate in patients with active rheumatoid arthritis who have had an inadequate response to at least 1 DMARD treatment.
- Trial name
- NCT02006706
- Testing
- rituximab [MabThera/Rituxan], methotrexate, methylprednisolone
- Where
- 3 sites in Serbia
- Volunteers
- 15 people
- Sponsor
- Hoffmann-La Roche
Osteolymphoma
Chemotherapy and Radiotherapy for Osteolymphoma
This trial is intended to determine the results obtained when standard treatment for Non Hodgkin's lymphoma is applied to the disease in a rare subtype which arises in bone.
- Trial name
- NCT00141648
- Testing
- Cyclophosphamide, Doxorubicin, Vincristine, Prednisolone., Radiotherapy
- Where
- 20 sites in Australia, New Zealand
- Volunteers
- 70 people
- Sponsor
- Trans Tasman Radiation Oncology Group
Thyroid-associated Ophthalmopathy
Trial of Rituximab for Graves' Ophthalmopathy
This study is being done to investigate the effects (good and bad) of Rituximab for the treatment of an autoimmune eye disease called Graves' ophthalmopathy. This disease has proven to be difficult to treat.
- Trial name
- NCT00595335
- Testing
- Rituximab, Saline, Methylprednisolone
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Rebecca Bahn
Multiple Myeloma
VMP Regimen - Safety, Efficacy, and Optimal Dose Finding Study for Patients With Multiple Myeloma
The 3-drug therapy of Bortezomib-Melphalan-Prednisolone (VMP) is a standard therapy that is commonly used currently in South Korea as a first-line treatment for treatment-naïve patients with multiple myeloma who are ineligible…
- Trial name
- VISION (NCT04151615)
- Where
- 24 sites in South Korea
- Volunteers
- 203 people
- Sponsor
- Boryung Pharmaceutical Co., Ltd
End-stage Renal Failure, Kidney Graft Rejection
Reference Group Trial for The ONE Study
To investigate the progression of the immunological response in living-donor kidney transplant recipients treated with a standard immunosuppressive regimen.
- Trial name
- NCT01656135
- Testing
- Blood drawing for immune monitoring and questionnaires
- Where
- 8 sites in United States, France and 3 more
- Volunteers
- 70 people
- Sponsor
- University of Regensburg
Pain
Prednisolone for Pain Reduction in Knee OA
Background: Osteoarthritis (OA), a common disabling condition, is the commonest type of arthritis worldwide. Knee OA is the 4th leading cause of disability in women.
- Trial name
- NCT01619163
- Testing
- Prednisolone
- Where
- Egypt
- Volunteers
- 125 people
- Sponsor
- University of Alexandria
Neoplasms, Nausea
Palonosetron Plus Dexamethasone in Moderately Emetogenic Chemotherapy Induced Nausea and Vomiting (Study P04594)
The purpose of this study is to determine if a single intravenous (IV) dose of palonosetron 0.25 mg plus a single IV dose of dexamethasone 8 mg is effective to prevent nausea and vomiting induced by moderately emetogenic…
- Conditions
- Neoplasms, Nausea, Vomiting
- Trial name
- NCT00687011
- Testing
- Palonosetron and Dexamethasone
- Volunteers
- 118 people
- Sponsor
- Merck Sharp & Dohme LLC
Behcet's Syndrome
Rituximab for the Treatment of Severe Ocular Manifestations of Behcet's Disease
The purpose of this study is to find if Rituximab can improve severe ocular lesions of Behcet's Disease.
- Trial name
- NCT00664599
- Testing
- Rituximab, Cytotoxic Combination
- Where
- Iran
- Volunteers
- 20 people
- Sponsor
- Tehran University of Medical Sciences
Adrenoleukodystrophy, Metachromatic Leukodystrophy
Stem Cell Transplant for Inborn Errors of Metabolism
The purpose of this study is to determine the safety and engraftment of donor hematopoietic cells using this conditioning regimen in patients undergoing a hematopoietic (blood forming) cell transplant for an inherited metabolic…
- Conditions
- Adrenoleukodystrophy, Metachromatic Leukodystrophy, Globoid Cell Leukodystrophy, Gaucher's Disease
- Trial name
- NCT00176904
- Testing
- Stem Cell Transplant, Busulfan, Cyclophosphamide, Antithymocyte Globulin
- Where
- United States
- Volunteers
- 135 people
- Sponsor
- Masonic Cancer Center, University of Minnesota
Suspected Appendicitis
Preoperative Methylprednisolone to Patients Suspected of Appendicitis Undergoing Laparoscopy
To test whether 125 mg preoperative methylprednisolone intravenously can reduce postoperative pain after laparoscopy for suspected appendicitis and to test whether preoperative methylprednisolone can reduce postoperative fatigue…
- Trial name
- NCT02711449
- Testing
- Methylprednisolone, 0.9% Saline
- Where
- 2 sites in Denmark
- Volunteers
- 78 people
- Sponsor
- Jakob Kleif
CHRONIC POST-TRAUMATIC NEUROPATHIC PAIN IN ANKLE AND FOOT
Pilot RCT of Efficacy of Perineural Local Anesthetics and Steroids for Chronic Post-traumatic Ankle and Foot Pain
Injections of local anesthetics (freezing) and steroids are often performed around injured nerves in individuals with nerve injury-related pain.
- Trial name
- PREPLANS (NCT02680548)
- Testing
- 0.9% saline, 0.25% bupivacaine hydrochloride injectable suspension USP, 4mg/cc methylprednisolone acetate injectable suspension USP
- Where
- Canada
- Volunteers
- 8 people
- Sponsor
- University Health Network, Toronto
Graft-versus-host Disease (GVHD)
Study of Itacitinib in Combination With Corticosteroids for the Treatment of Acute GVHD
To determine if Itacitinib in combination with corticosteroids is safe and tolerable in patients with Grade IIB-IVD acute graft-versus-host disease (GVHD).
- Trial name
- NCT02614612
- Testing
- Itacitinib (200 mg), Itacitinib (300 mg), prednisone or methylprednisolone (corticosteroids)
- Where
- 23 sites in United States
- Volunteers
- 31 people
- Sponsor
- Incyte Corporation
Early Chikungunya Arthritis
Efficacy of Starting Methotrexate Early in Chikungunya Arthritis
This is a single center, prospective, randomized controlled open label trial with a one sided cross over design to compare the efficacy of initiating Methotrexate(Mtx) in early post Chikungunya induced arthritis (4-12 weeks after…
- Trial name
- NCT03058471
- Testing
- Methotrexate, NSAID, Steroids
- Where
- India
- Volunteers
- 60 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Language Disorders in Children
EEG Changes in Pediatrics With Language Dysfunction Evaluation of Sleep EEG Changes in Paediatric Patients With Language Dysfunction: A Follow up Study. EEG Changes in Pediatrics With Language Dysfunction
In general, the severity of the patients' language disorders fluctuated with the degree of EEG epileptiform activity . Since then, a spectrum of disorders, often referred to collectively as the epilepsy-aphasia spectrum, have…
- Trial name
- NCT05487521
- Testing
- Methylprednisolone and or prednisolone
- Where
- Egypt
- Volunteers
- 93 people
- Sponsor
- Ain Shams University
Immune Thrombocytopenic Purpura
A Randomized Study of IVIG vs. IVIG With High Dose Methylprednisolone in Childhood ITP.
Childhood immune thrombocytopenia purpura (ITP) is a disorder characterized by the production of antibodies against platelets, resulting in enhanced destruction of platelets.
- Trial name
- NCT00376077
- Testing
- Methylprednisolone and IVIG
- Where
- Canada
- Volunteers
- 32 people
- Sponsor
- The Hospital for Sick Children
Pulmonary Disease, Chronic Obstructive
Prednisolone Novel Endpoint Study in Patients With Chronic Obstructive Pulmonary Disease (COPD)
Prednisolone will be used as a model medication to identify new clinical outcomes for future evaluation of new therapies in short-term studies (up to 4 weeks) in patients with Chronic Obstructive Pulmonary Disease (COPD).
- Trial name
- NCT00379730
- Testing
- Prednisolone
- Where
- 5 sites in Argentina, Chile and 2 more
- Volunteers
- 90 people
- Sponsor
- GlaxoSmithKline
Pneumonia
Steroid Dosing by bioMARker Guided Titration in Critically Ill Patients With Pneumonia
This research study is being done to determine the appropriate dose of steroids and the appropriate duration for steroid use to reduce inflammation in severe pneumonia needing a form of breathing support.
- Trial name
- NCT03852537
- Testing
- Methylprednisolone, Usual Care
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Mayo Clinic
Sarcoidosis, Tuberculosis
Efficacy of Antituberculous Therapy in Management of Sarcoidosis
From the time sarcoidosis has been described, there has always been a belief that the disease is in some way related to tuberculosis.
- Trial name
- NCT01245036
- Testing
- Antituberculous therapy along with steroids
- Where
- India
- Volunteers
- 100 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Cataract Surgery
Omidria and Dexycu, or Omidria and Dextenza Compared to Topical Prednisolone Acetate 1% Following Cataract Surgery
This research will evaluate the efficacy of Omidria and Dexycu, Omidria and Dextenza, and Omidria and prednisolone acetate 1% in the resolution of post-operative inflammation and pain following cataract surgery.
- Trial name
- NCT04316936
- Testing
- Omidria, Dextenza (dexamethasone ophthalmic insert) 0.4mg, Dexycu, 9% Intraocular Suspension
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Silverstein Eye Centers
MEMBRANOUS NEPHROPATHY
Sequential Therapy With Tacrolimus and Rituximab in Primary Membranous Nephropathy
In this study, investigators will evaluated the long-term efficacy and safety (two years) of Tacrolimus-Rituximab (RTX) therapy compared to Methylprednisolone-Cyclophosphamide (CYC) therapy in patients with primary Membranous…
- Trial name
- STARMEN (NCT01955187)
- Testing
- TACROLIMUS, RITUXIMAB, METHYLPREDNISOLONE
- Where
- Spain
- Volunteers
- 86 people
- Sponsor
- Hospital Universitario 12 de Octubre
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