Clinical trials: Prednisolone, completed
Diabetes Mellitus, Steroid Diabetes
Sitagliptin Prophylaxis for Glucocorticoid-Induced Impairment of Glucose Metabolism in Males With the Metabolic Syndrome
The investigators will assess whether the DPP-inhibitor sitagliptin will ameliorate glucocorticoid-induced impairment of glucose metabolism and beta-cell dysfunction and thus could be used as a prophylaxis for…
- Conditions
- Diabetes Mellitus, Steroid Diabetes, Glucocorticoid-induced Diabetes, Beta-cell Function
- Trial name
- SPHINX (NCT00721552)
- Testing
- Sitagliptin 100 mg, Prednisolone 30 mg
- Where
- Netherlands
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Amsterdam UMC, location VUmc
Leukemia, Lymphoma
Bone Marrow Transplantation in Treating Patients With Leukemia, Myelodysplasia, or Lymphoblastic Lymphoma
RATIONALE: Bone marrow transplantation may be able to replace immune cells that were destroyed by chemotherapy or radiation therapy used to kill cancer cells.
- Conditions
- Leukemia, Lymphoma, Myelodysplastic Syndromes
- Trial name
- NCT00003187
- Testing
- filgrastim, cyclophosphamide, cyclosporine
- Where
- 13 sites in United States
- Volunteers
- 19 people
- Sponsor
- Virginia Commonwealth University
Hand, Foot, and Mouth Disease
Effectiveness and Safety of Chinese Medicine to Treat Hand, Foot, and Mouth Disease
The study is aimed to evaluate the effectiveness and safety of Xiyanping injection,a traditional Chinese medicine (TCM), in the treatment of severe type of hand, foot, and mouth disease (HFMD).
- Trial name
- NCT01554930
- Testing
- Western therapy (mannitol, methylprednisolone, immunoglobulin, febrifuge), Xiyanping injection plus western therapy
- Where
- 3 sites in China
- Volunteers
- 230 people
- Sponsor
- Jiangxi Qingfeng Pharmaceutical Co. Ltd.
Non-Hodgkin's Lymphoma
A Comparative Study for Non-Hodgkin's Lymphoma in Hepatitis B Virus Carriers
AIMS OF THE STUDY 1. To test if steroid-free chemotherapeutic regimens decrease the risk of HBV reactivation and hepatitis development in HBsAg (+) carriers. 2.
- Trial name
- NCT00262210
- Testing
- Cyclophosphamide Epirubicin Etoposide Prednisolone
- Where
- Taiwan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National Health Research Institutes, Taiwan
Alopecia Totalis, Alopecia Universalis
Safety and Efficacy of Oral Mega Pulse Methylprednisolone in Severe Therapy Resistant Alopecia Areata
Systemic Pulse Glucocorticoids have been shown to be effective in widespread Alopecia areata but not the totalis, universalis or ophiasic type.
- Conditions
- Alopecia Totalis, Alopecia Universalis, Ophiasic Alopecia
- Trial name
- NCT01167946
- Testing
- methylprednisolone sodium succinate
- Where
- Saudi Arabia
- Volunteers
- 42 people
- Sponsor
- King Saud University
Chronic Obstructive Pulmonary Disease
Intravenous Versus Oral Administration of Prednisolone in Exacerbations of Chronic Obstructive Pulmonary Disease (COPD)
Treatment with systemic corticosteroids for acute exacerbations of COPD results in the improvement of clinical outcomes. The optimal route of administration has not been rigorously studied in COPD.
- Trial name
- NCT00311961
- Testing
- Intravenous prednisolone, Oral prednisolone
- Where
- Netherlands
- Volunteers
- 256 people
- Sponsor
- Isala
Lymphoma
A Phase II Study VEPEMB In Patients With Hodgkin's Lymphoma Aged ≥ 60 Years
RATIONALE: Drugs used in chemotherapy, such as vinblastine, cyclophosphamide, procarbazine, prednisolone, etoposide, mitoxantrone, and bleomycin, work in different ways to stop cancer cells from dividing so they stop growing or…
- Trial name
- NCT00079105
- Testing
- bleomycin sulfate, cyclophosphamide, etoposide
- Where
- 54 sites in Germany, United Kingdom
- Volunteers
- 175 people
- Sponsor
- Newcastle-upon-Tyne Hospitals NHS Trust
Allergic Bronchopulmonary Aspergillosis
Trial on the Efficacy and Safety of Two Different Glucocorticoid Dose Regimens in Allergic Bronchopulmonary Aspergillosis
Allergic bronchopulmonary aspergillosis (ABPA) is a pulmonary disorder caused by a complex hypersensitivity response to antigens released by the fungus Aspergillus fumigatus.
- Trial name
- NCT00974766
- Testing
- Glucocorticoids
- Where
- India
- Volunteers
- 92 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Carpal Tunnel Syndrome
Platelet-Rich Plasma in the Treatment of Patients With Idiopathic Carpal Tunnel Syndrome
This is a randomized controlled trial in a cohort of Egyptian patients suffered from mild to moderate idiopathic carpal tunnel. They were randomly divided into two groups.
- Trial name
- NCT03863873
- Testing
- Platelet-Rich Plasma Injection Group
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Mansoura University
Psoriasis Vulgaris
Evaluation of Topical Antipsoriatics in the Psoriasis Plaque Test
The purpose of this study is to evaluate the efficacy of the topical therapies Protopic and Advantan as well as their combination against placebo in a Psoriasis Plaque Test
- Trial name
- NCT00236171
- Testing
- Protopic, Advantan, Blood and Urine Test, coherence tomography
- Where
- Germany
- Volunteers
- 14 people
- Sponsor
- Technische Universität Dresden
Asthma
Oral Prednisolone Dosing in Children Hospitalized With Asthma
This study hopes to determine the appropriate oral steroid dose for treating children hospitalized with asthma exacerbations. Practice guidelines from different countries recommend a wide range of doses, and the doses used in…
- Trial name
- NCT00257933
- Testing
- Prednisolone high dose, Prednisolone lower dose
- Where
- United States
- Volunteers
- 152 people
- Sponsor
- Children's Hospital of Philadelphia
Charcot Arthropathy, Diabetes Complications
Zoledronic Acid or Methylprednisolone for Active Charcot's Neuroarthropathy of Foot in Patients With Diabetes Mellitus
Charcot neuropathic osteoarthropathy (CNO) is a progressively destructive process resulting from significant peripheral neuropathy of almost any aetiology. Diabetes mellitus has emerged as the commonest cause of CNO.
- Trial name
- NCT03289338
- Testing
- Zoledronic Acid, Methylprednisolone
- Where
- India
- Volunteers
- 36 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Glaucoma
Steroids After Laser Trabeculoplasty for Glaucoma
The purpose of this study is to determine whether the choice of post-operative eye drop administered after selective laser trabeculoplasty (SLT) for glaucoma affects the efficacy in lowering intraocular pressure (IOP).
- Trial name
- SALT (NCT00981435)
- Testing
- Prednisolone 1%, Ketorolac, Artificial Tears
- Where
- 2 sites in United States
- Volunteers
- 97 people
- Sponsor
- Stanford University
Failed Back Surgery Syndrome, Lumbar Radiculopathy
EuroPainClinicsStudy IX ( EPCS IX )
This prospective investigator-initiated study compares the clinical effectiveness and safety of epiduroscopic adhesiolysis in patients with failed back surgery syndrome (FBSS) and in patients with lumbar radicular pain without…
- Conditions
- Failed Back Surgery Syndrome, Lumbar Radiculopathy, Chronic Low Back Pain, Epidural Fibrosis
- Trial name
- EPCS IX (NCT07411950)
- Testing
- Epiduroscopic mechanical adhesiolysis, Epidural pharmacologic therapy
- Where
- Slovakia
- Volunteers
- 141 people
- Sponsor
- EPC Education s.r.o.
Bell's Palsy, Facial Nerve Paresis
Intratympanic Steroid for Bell's Palsy
Facial nerve paralysis is due to inflammation around the facial nerve. Current treatment for facial nerve paralysis is a 10 day course of oral steroids (which will reduce the inflammation), with electrodiagnostic testing.
- Trial name
- NCT03508440
- Testing
- Intratympanic injection, Prednisone
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Missouri-Columbia
Status Asthmaticus
Phase I, Placebo-Controlled, Blinded Pilot Study of Ipratropium in Children Admitted to the ICU With Status Asthmaticus
This study is a Phase I study to investigate the addition of inhaled Ipratropium bromide to standard therapy in the treatment of severe asthma attacks in children admitted to the Pediatric Intensive Care Unit.
- Trial name
- NCT02872597
- Testing
- Ipratropium, 0.9% Sodium Chloride, Albuterol
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University Hospitals Cleveland Medical Center
Graft Rejection, Kidney Failure
Study Comparing Two Immunosuppressive Regimens in De Novo Renal Allograft Recipients
Evaluate renal graft function (based on the calculated Glomerular Filtration Rate) at 12 months after transplantation in patients receiving either a regimen of sirolimus plus mycophenolate mofetil following an antibody induction…
- Conditions
- Graft Rejection, Kidney Failure, Kidney Transplantation
- Trial name
- NCT00261820
- Testing
- tacrolimus, mycophenolate mofetil, methylprednisolone
- Volunteers
- 160 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Critical Illness, Pneumonia, Viral
Comparison Between Different Doses of Steroids in COVID-19 Patients
aim of this study is to compare between standard dose methyl prednisolone and mega dose methyl prednisolone as regards outcome reflected by mortality rate, percentage of mechanically ventilated patients and icu length of stay of…
- Trial name
- COVID-19 (NCT05279482)
- Testing
- observation for outcome of methylprednisolone dose
- Where
- 2 sites in Egypt
- Volunteers
- 104 people
- Sponsor
- Ain Shams University
Kidney Transplantation
Benefit of Early Protocol Biopsy and Treatment of Subclinical Rejection
This multicentre randomized, controlled trial (RCT) compared renal allograft histology and function in subjects treated with Tacrolimus + MMF + prednisone undergoing early protocol biopsies and treatment of subclinical rejection…
- Trial name
- NCT00885820
- Testing
- Tacrolimus, MMF, Corticosteroids (Prednisone)
- Where
- 12 sites in United States, Canada
- Volunteers
- 240 people
- Sponsor
- Astellas Pharma Inc
Diabetes Mellitus, Type 2
Study to Assess the Effect on Glucose Homeostasis of Two Dose Levels of AZD9567, Compared to Prednisolone, in Adults With Type 2 Diabetes
The study is intended to assess the effect on glycaemic control of AZD9567, as measured by the glucose AUC(0-4) versus baseline following a standardised mixed meal tolerance test (MMTT), compared to prednisolone in adults with…
- Trial name
- NCT04556760
- Testing
- AZD9567, Prednisolone
- Where
- 3 sites in Germany
- Volunteers
- 46 people
- Sponsor
- AstraZeneca
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