Clinical trials: Prednisolone, completed
De Novo Kidney Transplantation
A Study to Assess the Efficacy and Safety of Alefacept in Kidney Transplant Recipients
The purpose of this study is to determine whether alefacept is effective and well tolerated when used with a combination of tacrolimus, mycophenolate mofetil and steroids versus a combination therapy of placebo, tacrolimus and…
- Trial name
- NCT00617604
- Testing
- Alefacept, Tacrolimus, Mycophenolate Mofetil
- Where
- 33 sites in Austria, Belgium and 10 more
- Volunteers
- 218 people
- Sponsor
- Astellas Pharma Inc
Uveitis, Intermediate
Myfortic for the Treatment of Non-infectious Intermediate Uveitis
The objective of this clinical trial is to evaluate the efficacy, safety and tolerability of enteric-coated mycophenolate sodium (Myfortic®) in combination with low-dose corticosteroids (Decortin H®) compared to a monotherapy…
- Trial name
- MYCUV-IIT02 (NCT01092533)
- Testing
- Myfortic, Decortin
- Where
- 5 sites in Germany
- Volunteers
- 44 people
- Sponsor
- STZ eyetrial
Lymphoma
Combination Chemotherapy With or Without Bortezomib in Treating Patients With Relapsed or Refractory Mantle Cell Lymphoma
RATIONALE: Drugs used in chemotherapy, such as cyclophosphamide, doxorubicin, vincristine, and prednisolone, work in different ways to stop the growth of cancer cells, either by killing the cells or stopping them from dividing.
- Trial name
- NCT00513955
- Testing
- bortezomib, cyclophosphamide, doxorubicin hydrochloride
- Where
- 25 sites in United Kingdom
- Volunteers
- 50 people
- Sponsor
- University Hospital Plymouth NHS Trust
Type 1 Diabetes
Calcineurin Inhibitor (CNI)-Free Immunosuppressive Regimen in T1D Patients Receiving Islet Transplantation
Our final objective is to develop an adoptive therapy with tolerogenic donor-specific Tr1 cells in T1D patients undergoing pancreatic islet transplantation (Tx).
- Trial name
- ECIT-1 (NCT01346085)
- Testing
- CNI free immunosuppression
- Where
- 2 sites in Italy, Switzerland
- Volunteers
- 10 people
- Sponsor
- Ospedale San Raffaele
Lupus Erythematosus, Systemic
Lymphocyte Depletion and Stem Cell Transplantation to Treat Severe Systemic Lupus Erythematosus
This study will examine a new approach to treating patients with severe systemic lupus erythematosus (SLE) that involves collecting stem cells (cells produced by the bone marrow that develop into blood cells) from the patient…
- Trial name
- NCT00076752
- Testing
- fludarabine phosphate, cyclophosphamide, Rituxan (rituximab)
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- National Cancer Institute (NCI)
Lateral Epicondylitis, Comparing Autologous Blood Corticosteroid and Their Combined Injection for Treating Lateral Epicondylitis
Comparing Autologous Blood, Corticosteroid, and Their Combined Injection for Treating Lateral Epicondylitis
The goal of this clinical trial is to compare autologous blood, corticosteroid, and their combined injection for treating lateral epicondylitis.
- Trial name
- NCT06236178
- Testing
- Corticosteroid, Autologous Blood, Local Anesthetic
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 119 people
- Sponsor
- Istanbul Training and Research Hospital
Multiple Sclerosis, Relapsing-Remitting
AVONEX® Combination Trial - "ACT"
The purpose of this study is to determine the efficacy and safety of combination therapy with AVONEX plus low dose oral methotrexate (MTX), every other month courses of intravenous methylprednisolone (IVMP), or both in patients…
- Trial name
- NCT00112034
- Testing
- Methotrexate, IV methylprednisolone
- Where
- United States
- Volunteers
- 350 people
- Sponsor
- Biogen
Immunosuppression
Once-daily Regimen With Envarsus® to Optimize Immunosuppression Management and Outcomes in Kidney Transplant Recipients
With the availability of well-studied once-daily formulations of tacrolimus, the ability to achieve a true once-daily immunosuppressant regimen along with everolimus and steroids may finally be achievable and have the potential…
- Trial name
- NCT02954198
- Testing
- Tacrolimus, Prednisone, Mycophenolate mofetil
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Medical University of South Carolina
Smell Loss
Preparation and Characterization Intranasal Film Loaded With Steroid as a Local Treatment of Anosmia in Compare to Insulin Intranasal Film
This study is a growing step of phase I study published on March 2021. The study was implicated on Minia university on small scale of patient (20) to investigate the impact of insulin as fast dissolving films for intranasal…
- Trial name
- NCT05328414
- Testing
- Prednisolone
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Deraya University
Allergic Conjunctivitis
Study Evaluating the Efficacy and Safety of PRT-2761 for the Treatment of Acute and Chronic Allergic Conjunctivitis
To evaluate the efficacy and safety of two concentrations of PRT-2761 as a topical ophthalmic solution for the treatment of the signs and symptoms of acute and chronic allergic conjunctivitis.
- Trial name
- NCT03320434
- Testing
- PRT-2761 0.5%, PRT-2761 1%, Patanol
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- ORA, Inc.
Recurrent Glioblastoma (WHO-Grade IV Glioma)
Clinical Trial on the Combination of Avelumab and Axitinib for the Treatment of Patients With Recurrent Glioblastoma
Phase II clinical trial on the combination of avelumab and axitinib for the treatment of patients with recurrent glioblastoma (histologically confirmed WHO grade IV glioma), at documented recurrence/progression following prior…
- Trial name
- GliAvAx (NCT03291314)
- Testing
- Axitinib, Avelumab
- Where
- Belgium
- Volunteers
- 52 people
- Sponsor
- Universitair Ziekenhuis Brussel
Myeloproliferative Neoplasms
Pomalidomide in Patients With Myeloproliferative Neoplasms in Fibrotic Stage
This is a phase II, multi-center study of pomalidomide in adult patients with PMF, SMF, and unclassifiable MPN showing at least grade 1 bone marrow fibrosis and requiring therapy.
- Trial name
- NCT00949364
- Testing
- Pomalidomide
- Where
- 15 sites in Germany
- Volunteers
- 103 people
- Sponsor
- University of Ulm
Multiple Myeloma
An Efficacy and Safety Study of Daratumumab in Patients With Multiple Myeloma Who Have Received at Least 3 Prior Lines of Therapy (Including a Proteasome Inhibitor [PI] and Immunomodulatory Drug [IMiD]) or Are Double Refractory to a PI and an IMiD
The purpose of this study is to evaluate the efficacy and safety of 2 daratumumab treatment regimens in participants with multiple myeloma who have received at least 3 prior lines of therapy (including a proteasome inhibitor [PI]…
- Trial name
- NCT01985126
- Testing
- Daratumumab 16 mg/kg (Part 1), Daratumumab 8 mg/kg (Part 1), Methylprednisolone
- Where
- 23 sites in United States, Canada and 1 more
- Volunteers
- 124 people
- Sponsor
- Janssen Research & Development, LLC
Osteoarthritis, Knee
Liposomal Bupivacaine Versus Standard of Care in Total Knee Surgery
The purpose of this study is to determine whether liposomal bupivacaine is effective in the management of pain following total knee arthroplasty, as compared to standard of care analgesia.
- Trial name
- NCT02219087
- Testing
- Liposomal bupivacaine, Standard of Care
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- OhioHealth
COVID-19, Methylprednisolone
Investigation of Hospitalisation Times and Mortality According to Drug Dose in Patients Given Systemic Methylprednisolone With a Pre-diagnosis of Covid-19 Pneumonia; Retrospective Study
Aim:There is still not enough data to determine methylprednisolone treatment timing, dosage, duration of use and indication in Covid 19 pneumonia.
- Conditions
- COVID-19, Methylprednisolone, Pneumonia
- Trial name
- NCT04847687
- Testing
- methylprednisolone
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Multiple Sclerosis
Oral Corticotherapy in Megadoses to Treat Multiple Sclerosis During Relapse
This is a phase IV, multicenter, randomized, double blind clinical trial. The investigators will study 48 patients with remitting relapsing multiple sclerosis (MS) experiencing moderate or severe attack receiving immunomodulatory…
- Trial name
- NCT00753792
- Testing
- methylprednisolone
- Where
- 7 sites in Spain
- Volunteers
- 49 people
- Sponsor
- Germans Trias i Pujol Hospital
Postoperative Pain
Depomedrol for Genicular Nerve Block.
This study is designed to test the efficacy of adding Depomedrol a long-acting steroid to bupivacaine for relieving postoperative pain and reducing opioid requirements following total knee replacement surgery.
- Trial name
- NCT05893771
- Testing
- Methylprednisolone Injection, Bupivacaine Hcl 0.5% Inj_#2, normal saline
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Menoufia University
Impacted Mandibular Third Molar Extraction, Postoperative Pain Control
Evaluation of Corticosteroid Administration Following Impacted Third Molar Surgery Using 3-Dimensional Facial Analysis
The purpose of this prospective, randomized, controlled, single-blind clinical trial is to compare the efficacy of local submucosal administration of dexamethasone versus methylprednisolone on postoperative morbidity following…
- Conditions
- Impacted Mandibular Third Molar Extraction, Postoperative Pain Control, Postoperative Edema and Pain
- Trial name
- NCT07628166
- Testing
- Surgical Extraction of Impacted Mandibular Third Molar, methylprednisolone sodium succinate, Dexamethasone Sodium Phosphate Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Irfan Üstündağ
Infantile Spasms, West Syndrome
Prednisolone in Infantile Spasms- High Dose Versus Usual Dose
Infantile spasms comprise a difficult to treat type of epilepsy in young children. Hormonal treatment, i.e. Prednisolone and ACTH are considered the treatment of choice.
- Trial name
- NCT01575639
- Testing
- Oral prednisolone
- Where
- India
- Volunteers
- 63 people
- Sponsor
- Lady Hardinge Medical College
Acute Exacerbation of Asthma
Dexamethasone Versus Prednisolone in Acute Exacerbation of Childhood Asthma
Because of insufficient local comparative data, this study was designed to determine the outcome of intravenous dexamethasone in contrast to oral prednisolone in acute exacerbation of asthmatic children.
- Trial name
- NCT07275593
- Testing
- Dexamethasone, Prednisolone
- Where
- Pakistan
- Volunteers
- 224 people
- Sponsor
- Muhammad Aamir Latif
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