Clinical trials: Probiotic, completed
Inflammation
COVID-19 Pneumonia and Gut Inflammation
The primary objective of our study was to evaluate the efficacy of a mix of three probiotic strains (Bifidobacterium lactis LA 304, Lactobacillus salivarius LA 302, and Lactobacillus acidophilus LA 201; Lactibiane Iki®) in the…
- Trial name
- NCT05781945
- Testing
- probiotics, standard therapy
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Cerebral Palsy, Chronic Constipation
Synbiotic, Prebiotics and Probiotics in Children With Cerebral Palsy and Constipation
Randomized double blind controlled clinical trial. Participants will be enrolled at the New Civil Hospital of Guadalajara "Dr. Juan I. Menchaca" during the period from May 2017 to July 2018, from six to 59 months of either sex.
- Trial name
- NCT03117322
- Testing
- agave inulin, Lactobacillus reuteri DSM 17938, maltodextrin
- Where
- Mexico
- Volunteers
- 40 people
- Sponsor
- Andrea Garcia Contreras
Stunting, Obesity
Effects of Probiotics and Calcium Supplementation on Growth, Development, and Metabolic Parameters
Stunting is still a major problem in developing countries, including Indonesia, and has been associated with impaired development. Stunted children have also a higher risk of metabolic syndrome in adulthood.
- Conditions
- Stunting, Obesity, Cognitive Function 1, Social, Depression
- Trial name
- PROBIOCAL (NCT04046289)
- Testing
- Low Calcium Milk, Regular Calcium Milk, Probiotic 1
- Where
- Indonesia
- Volunteers
- 238 people
- Sponsor
- Universitas Indonesia
Military Training
The Effects of Probiotic and HMB Supplementation on Immune and Digestive Function in Special Operations Soldiers
The study will determine whether acute ingestion of a probiotic combined with beta-hydroxy-beta-methylbutyrate (HMB) can enhance immune and digestive function in soldiers during 8-weeks of advanced infantry training.
- Trial name
- NCT02762968
- Testing
- HMB, BC30
- Where
- Israel
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Metabolic Technologies Inc.
Diarrhea, Constipation
Probiotics and Hospital Outcome in the Elderly
Probiotics have been shown to reduce the rate of diarrhea and constipation. The purpose of this study was to investigate if probiotics could improve outcome of hospitalized orthopedic elderly patients.
- Trial name
- PROAGE (NCT00794924)
- Testing
- VSL#3
- Volunteers
- 345 people
- Sponsor
- Kaplan-Harzfeld Medical Center
White Spot Lesion of Tooth, Long Term Adverse Effects
Comparison of Efficacy Of Probiotic Toothpaste and Chlorhexidine Mouthwash To Reduce S.Mutans
Orthodontic appliance causes increase in plaque accumulation, especially around brackets, wires and attachments. Advances in orthodontics in recent time have led to improved quality of appliance and treatment procedures…
- Conditions
- White Spot Lesion of Tooth, Long Term Adverse Effects, Caries, Dental, Orthodontic Appliance Complication
- Trial name
- NCT03004196
- Testing
- Probiotic Toothpaste, Dr. Reddy's Clohex, Control Group
- Where
- India
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Peoples University, Bhanpur, Bhopal
Low-grade Inflammation, Increased Intestinal Permeability
Probiotics Against Low Grade Inflammation and Increased Intestinal Permeability in the Elderly
The purpose of this study is to evaluate the ability of a blend of berries and probiotics in reducing low-grade inflammation and intestinal permeability in the elderly. The intervention period is one month.
- Trial name
- NCT02342496
- Testing
- Active, only probiotics, Active, blend of berries and probiotics
- Where
- Sweden
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Probi AB
Urinary Tract Infection in Pregnancy
Lactobacillus Reuteri for Treatment of Uncomplicated UTI in Pregnant Women
Prevalence of uro-genital infections during pregnancy move between 7% to 12% in developed countries, meanwhile in developing countries this figure moved between 14% and until 55%, such is the case of Mexico.
- Trial name
- UTIPregnant (NCT03362697)
- Testing
- Probiotics, Antibiotics
- Where
- Mexico
- Volunteers
- 150 people
- Sponsor
- Innovacion y Desarrollo de Estrategias en Salud
Root Canal Treatment, Irreversible Pulpitis With Apical Periodontitis
Effect of Probiotics, Double Antibiotic Paste, and Calcium Hydroxide on Postoperative Pain in Irreversible Pulpitis: A Randomized Trial
The goal of this clinical trial is to learn whether probiotics, double antibiotic paste (DAP), or calcium hydroxide paste help reduce postoperative pain after root canal treatment in adults with symptomatic irreversible pulpitis.
- Conditions
- Root Canal Treatment, Irreversible Pulpitis With Apical Periodontitis, Pulpitis - Irreversible, Post Operative Pain, Acute
- Trial name
- NCT07270159
- Testing
- Probiotic
- Where
- Pakistan
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Proof of Concept
Dietary Intervention Detection in the Small Intestine
Proof of concept study to validate the ability of a capsule device to gather samples from the small bowel for microbiome analysis in adults and to detect dietary changes from simultaneous ingestion of a probiotic.
- Trial name
- NCT04489329
- Testing
- Ingestible Capsule, Probiotic
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Nimble Science Ltd.
Dry Skin
Evaluation of Skin Hydration in Adults With Dry Skin Using a Moisturizer With an Added Sterilized Probiotic
Double-blind placebo-controlled clinical trial to evaluate the effectiveness of a sterilized probiotic on skin health and hydration in adults with dry skin.
- Trial name
- DAMP (NCT05013645)
- Testing
- Sterilized probiotic LfQi601
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Florida State University
Irritable Bowel Syndrome, Digestive System Diseases
Efficacy of a Multi-strain Probiotic in the Treatment of Irritable Bowel Syndrome (IBS)
The Canadian College of Naturopathic Medicine is conducting a research study on Irritable Bowel Syndrome (IBS), a common condition in North America.
- Conditions
- Irritable Bowel Syndrome, Digestive System Diseases, Colonic Diseases, Functional, Colitis, Mucous
- Trial name
- NCT01176227
- Testing
- Kyodophilus multi-strain probiotic capsules
- Where
- Canada
- Volunteers
- 128 people
- Sponsor
- The Canadian College of Naturopathic Medicine
Hyperbilirubinemia, Neonatal
Effect of Probiotic Lacobacillus Reuterii on Serum Bilirubin Levels in Preterm Infants
The goal of this clinical trial is to learn about the effect of probiotic Lactobacillus reuterii on the level of serum bilirubin in moderately and late preterm infants with birth weights 1000 grams to 2499 grams who were admitted…
- Trial name
- NCT06672406
- Testing
- Lactobacillus reuterii
- Where
- Indonesia
- Volunteers
- 40 people
- Sponsor
- Hasanuddin University
Mental Health Wellness
Probiotics Effect on Mental Wellness
The goal of this clinical trial is to compare the effect of a probiotic strain on mental wellbeing in moderately stressed, healthy, adults in the general population.
- Trial name
- Moa (NCT05709067)
- Testing
- Probiotic
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Fonterra Research Centre
Hypothyroidism
Interaction Between Levothyroxine and Probiotics in Hypothyroid Patients
A prospective, randomized, single-blind, controlled, investigator-started clinical trial was carried out. Patients with primary hypothyroidism were randomly assigned to the study (VSL#3®+ LT4) and the control group (LT4).
- Trial name
- NCT03095963
- Testing
- a mixture of highly charged Lactobacilli and Bifidobacteria (VSL#3®), levothyroxin
- Volunteers
- 80 people
- Sponsor
- Azienda USL Modena
Gastrointestinal, Overweight , Obesity
A Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Impact of CLB101TM️ on Gut Health in Healthy, Overweight Individuals
Anaerostipes caccae CLB101TM️ is a next-generation probiotic isolated from healthy humans. It was shown to be in decreased abundance in people with protein-based food sensitivities/allergies.
- Trial name
- NCT07336615
- Testing
- CLB101™️
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- ClostraBio Inc.
Periodontitis, Probiotics
Effects of Probiotic Therapy in the Treatment of Periodontitis.
The aim of this study is to evaluate the effect of the probiotic therapy as an adjunct to non-surgical periodontal treatment in patients diagnosed with Generalized Chronic Periodontitis.
- Trial name
- NCT03408548
- Testing
- Scaling root planning, Probiotic
- Where
- Brazil
- Volunteers
- 41 people
- Sponsor
- University of Sao Paulo
Nutrition, Healthy
Effect of L. Plantarum Probiotic Supplementation on Broccoli Sulforaphane Bioavailability: Randomised Double-blind Placebo-controlled Crossover Study
Broccoli has the precursor of an active compound (sulforaphane) that has shown a wide range of health promoting benefits. Sulforaphane formation depends on the conversion of glucoraphanin (precursor) by myrosinase enzyme.
- Trial name
- PRO-BROC (NCT06561893)
- Testing
- Broccoli sprouts extract supplementation
- Where
- 2 sites in United Kingdom
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Exeter
Adhd, ALS
National Multicenter Interventional Study Aimed at Evaluating the Effect on the Intestinal Microbiota in Chronically Frail Patients Who Share Alterations in Intestinal Function.
The objective of the study will be to understand whether a supplementation of the diet with an active symbiotic, i.e. characterized by a mix of probiotics and a specially selected fiber with prebiotic activity combined with a…
- Conditions
- Adhd, ALS, Bronchial Asthma
- Trial name
- sPATIALS3 (NCT06005506)
- Testing
- Prebiotic fiber, Dietary fiber, Probiotic
- Where
- 4 sites in Italy
- Volunteers
- 64 people
- Sponsor
- Institute of Biomedical Technologies-National Research Council, Italy
Iron Absorption
Iron Absorption From an Iron-fortified Follow-up Formula With Added Synbiotic or Human Milk Oligosaccharides
The co-primary objectives of this study are: 1) to investigate the effect adding a synbiotic (combination of a pre-and probiotic) to iron-fortified follow-up formula (FUF) on iron bioavailability, and 2) to investigate the effect…
- Trial name
- NCT04774016
- Testing
- Test formula A without added pre- and pro-biotic, Test formula B with synbiotic, Test formula C with HMOs
- Where
- Thailand
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)