Clinical trials: Probiotic, completed
Colorectal Cancer
Probiotics In Colorectal Cancer Patients
Design: double blind controlled randomized trial with a parallel design and 3 treatment groups Description of subjects: Patients admitted in study centers for colorectal surgery under laporoscopy and/or laparotomy.
- Trial name
- NCT00936572
- Testing
- Probiotics (La1, BB536)
- Where
- Italy
- Volunteers
- 35 people
- Sponsor
- University of Milano Bicocca
Type 2 Diabetes
Effects of Genmont Probiotic on Improve the Level of Blood Glucose and Other Diabetic Associate Parameter in Type 2 Diabetes Patients
The purpose of this study is to evaluate the efficacy and safety of probiotics ADR-1/GMNL-263 capsules (Lactobacillus reuteri ADR-1/ Lactobacillus reuteri GMNL-263) for the treatment of adults with type2 DM.
- Trial name
- NCT02274272
- Testing
- ADR-1, GMNL-263
- Where
- Taiwan
- Volunteers
- 86 people
- Sponsor
- GenMont Biotech Incorporation
Depression, Anxiety
Effects of Probiotics on Mood
Recent demonstration that probiotics administration has positive effects on depressive feelings in healthy populations suggests its possible role as an adjuvant therapy for depression in clinical populations and as a non-invasive…
- Trial name
- NCT03539263
- Testing
- Bifihappy
- Where
- Italy
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Probiotical S.p.A.
Overweight
Evaluate the Efficacy and Safety of LMT1-48 on Reducing Body Fat in Overweight Subject
The purpose of this study is to evaluate the safety and efficacy of LMT1-48(Probiotics) compared to a placebo in reducing the body fat in overweight subjects
- Trial name
- NCT03759743
- Testing
- LMT1-48
- Where
- South Korea
- Volunteers
- 97 people
- Sponsor
- Medy-Tox
Tolerance
Assessing Early Behavioral Indicators of Formula Tolerance
The study is intended to assess the amount of crying and fussiness in infants fed an infant formula containing probiotics.
- Trial name
- NCT02340143
- Testing
- Control, Investigational
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Mead Johnson Nutrition
Hyperuricemia
Possible Pharmacological Effect of Quercetin in the Management of Hyperuricemia - Results From Real-life Clinical Studies
Quercetin, a natural flavonoid found in various fruits and vegetables, has gained attention for its potential role in managing hyperuricemia.
- Trial name
- NCT06652035
- Testing
- Quevir® (Quercetin Phytosome®), Bactoblis®
- Where
- Italy
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- Liaquat University of Medical & Health Sciences
Irritable Bowel Syndrome
A Novel Probiotic Mixture in Adults With IBS
Irritable bowel syndrome (IBS) is faced by gastroenterologists on a daily basis and probiotics are a potential therapeutic tool, however, there is no strain recommendations.
- Trial name
- IBS-dammil5 (NCT06610149)
- Testing
- Probiotic mixture
- Where
- Italy
- Volunteers
- 1,098 people
- Sponsor
- University of Bari
Gastrointestinal Symptoms, Small Intestinal Overgrowth
Proton Pump Inhibitors and Gastrointestinal Symptoms
The aim of the study is to evaluate the potential protective effect of Lactobacillus paracasei subspecies paracasei F19 administration on bowel symptom onset in patients with gastro-esophageal reflux disease at long-term PPI…
- Trial name
- NCT02054455
- Testing
- Lactobacillus paracasei F19
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Federico II University
Gastrointestinal Disease Symptoms
Ritual Synbiotic+, a Dietary Supplement Designed to Impact Gastrointestinal Health, Mood, and Behavior in Women
The aim of this study is to determine how regular consumption of Synbiotic+, a dietary supplement that contains prebiotics, probiotics, and postbiotics, impacts functional gastrointestinal health, markers of intestinal…
- Trial name
- SYN (NCT06834984)
- Testing
- Prebiotic, probiotic, postbiotic combination
- Where
- United States
- Volunteers
- 103 people
- Sponsor
- Colorado State University
Seasonal Affective Rhinitis, Asthma
Seasonal Allergic Rhinitis Study
The study aims to examine the effect of probiotics on the clinical symptoms of allergic rhinitis and to elucidate some of the immunological mechanisms involved.
- Conditions
- Seasonal Affective Rhinitis, Asthma, Grass Allergy
- Trial name
- SAR (NCT01123252)
- Testing
- Lactobacillus casei Shirota (LcS)
- Where
- 4 sites in United Kingdom
- Volunteers
- 60 people
- Sponsor
- University of East Anglia
Immune Surveillance
Acute Immune Modulation by Probiotic Strain
Clinical proof-of-concept study, comparing the acute immune impacts of 3 doses of a probiotic strain to a placebo. This study involves twenty-four participants, composed of healthy adults, who will be taking a placebo and 3…
- Trial name
- NCT06754228
- Testing
- Probiotic Agent
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Natural Immune Systems Inc
Obesity, Dysbioses
Use of Probiotic Yogurt in Obese Women
This study aimed to examine the effects of using probiotic yogurt on body components (body weight, height, etc.) and digestive system (distention, gas, etc.) in obesity (obese women), which is an important public health problem…
- Trial name
- NCT05364814
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 21 people
- Sponsor
- Yuksek Ihtisas University
Functional Constipation
Effect of Probiotics on Functional Constipation in Adults
Introduction: Functional constipation is a symptom-based gastrointestinal disorder without an organic origin (eg, bowel obstruction). It has a prevalence of 14% in adults.
- Trial name
- PROBCON (NCT04437147)
- Testing
- 3 Billion UFC strains of probiotics, 8 Billion UFC strains of probiotics
- Where
- Brazil
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Luciane Cruz Lopes
GERD
to Assess the Efficacy and Safety of the Probiotic E. Coli Strain M17 on Patients With GERD
The study is an Open Label, Prospective, Non Comparative, Pilot, clinical trial design. Patients with inadequate relief in GI symptoms associated with GERD despite PPI treatment will be screened and those who meet the inclusion…
- Trial name
- NCT00324532
- Testing
- ProBactrix
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- BioBalance Corporation
Tooth Extraction, Post-Op Complication
Antibiotic Therapy in Erupted Tooth Extractions
Evaluation of the efficacy of amox+clav and of a probiotic after tooth extraction. the aim is to evaluate efficacy of antibiotic therapy after tooth extractions in preventing infections as compared to no therapy, and efficacy of…
- Conditions
- Tooth Extraction, Post-Op Complication, Amoxicillin
- Trial name
- NCT04082598
- Testing
- Amoxicillin Clavulanate, Bifidobacterium longum and Lactoferrin
- Volunteers
- 165 people
- Sponsor
- Antonio Barone
Type 2 Diabetes, Metabolic Syndrome
Clinical Study on the Effect of a Synbiotic on Body Fat Mass
In this trial the effect of a synbiotic consisting of the three different strains of Lactobacillus fermentum and acacia gum (gum arabic) on body fat mass, body weight, long-term glycemia, insulin resistance and other risk factors…
- Conditions
- Type 2 Diabetes, Metabolic Syndrome, Obesity, Abdominal, Obesity, Visceral
- Trial name
- NCT04754464
- Testing
- synbiotic, microcrystalline cellulose
- Where
- 2 sites in Austria, Germany
- Volunteers
- 120 people
- Sponsor
- Slimbiotics GmbH
Functional Constipation
Effect of Lactobacillus Gasseri DSM 27123 on Functional Constipation in Healthy Women
The primary objective is to determine the change in frequency of complete spontaneous bowel movements (CSBMs) after 4 weeks of oral supplementation with Lactobacillus gasseri DSM 27123 in healthy adult women with functional…
- Trial name
- NCT02592200
- Testing
- Lactobacillus gasseri DSM 27123
- Where
- Sweden
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- BioGaia AB
Vaginitis, Dysbiosis
Oral Multi-Strain Lactobacillus Probiotic for Women With Vaginal Dysbiosis
Many women have an imbalance in their vaginal bacteria that can cause discomfort, irritation, and repeat infections. In a healthy vagina, helpful Lactobacillus bacteria are the main group of microbes.
- Conditions
- Vaginitis, Dysbiosis, Vaginal Diseases
- Trial name
- NCT07882134
- Testing
- Low-dose multi-strain Lactobacillus capsule, High-dose capsule
- Where
- South Korea
- Volunteers
- 119 people
- Sponsor
- Soon Chun Hyang University
Gluten Sensitivity, Wheat Sensitivity
Effects of a Probiotic Supplementation on Symptoms and Microbiome Characteristics in Patients With Non-celiac Gluten/Wheat Sensitivity.
The aim of this randomized, double-blind, placebo-controlled clinical trial is to investigate the effects of probiotics on symptoms and gut microbiota composition following gluten reintroduction.
- Trial name
- NCT06884241
- Testing
- Probiotic supplementation
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- University of Turin, Italy
Nutrition, Healthy, Gastrointestinal Microbiome
The Effects of a Nutritional Supplement on Nutrient Status and Quality of Life
This study is a randomized, double-blind, placebo-controlled study of N=120 apparently healthy men and women. The purpose of this study is to assess the effect of a novel dietary supplement on blood markers of nutrient status…
- Conditions
- Nutrition, Healthy, Gastrointestinal Microbiome, Healthy Aging
- Trial name
- NCT06332898
- Testing
- AG1 - Nutritional Supplement
- Where
- United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Athletic Greens International