Clinical trials: Propofol, completed
Abnormal Respiratory Airway Resistance
Effects of Dexmedetomidine and Propofol on Pulmonary Mechanics
The aim of this study is to compare the effects of dexmedetomidine and propofol on pulmonary mechanics in intensive care patients.
- Trial name
- NCT02330120
- Testing
- propofol, dexmedetomidine
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Cukurova University
Opioid Free Anesthesia
Opioid Free Anesthesia in Obese Patients.
Using opioids in the clinical practice of anesthesia was astonishing. They are good analgesics and used widely to modulate perioperative pain, but analgesia with these drugs can be associated with many side effects that may lead…
- Trial name
- NCT05481970
- Testing
- dexmedetomidine,ketamine,lidocaine,propofol, fentanyl,propofol
- Where
- Egypt
- Volunteers
- 76 people
- Sponsor
- Fayoum University Hospital
Lung Volume Reduction Surgery
Effects of Desflurane and Propofol During Lung Volume Reduction Surgery
Patients presenting for lung volume reduction are very high risk patients and it is important they receive the best anesthetic available. This study aims to answer which is the best anesthetic for managing such cases.
- Trial name
- NCT04226625
- Testing
- Propofol, Desflurane
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Columbia University
Delirium, Anesthesia
Incidence of Postoperative Delirium in Cancer Patients After Laparoscopic Surgery in Trendelenburg Position
Postoperative delirium is an acute mental syndrome that is caused by diffuse cerebral dysfunction resulting from the action of predisposing and precipitating factors acting together.
- Trial name
- NCT03572517
- Testing
- Subarachnoid block, Spinal morphine
- Where
- Brazil
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- AC Camargo Cancer Center
Rhytidoplasty
Anesthetics in Rhytidoplasty - A Comparison Study
This study is a prospective, double-blind, randomized comparison study of different anesthesia methods in rhytidoplasty surgery.
- Trial name
- NCT02410460
- Testing
- clonidine, glycopyrrolate, propofol
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Mercy Facial Plastic Surgery Center
Fluid Management During Elective Spine Surgeries
Conventional Fluid Management vs Plethysmographic Variability Index -Based Goal Directed Fluid Management
Plethysmographic variability index is a dynamic method for evaluation of volume status which depends on estimation of respiratory variations in pulse oximeter waveform amplitude.
- Trial name
- NCT05239286
- Testing
- General anaesthesia, Conventional fluid managment, PVI dependant goal directed fluid therapy
- Where
- Egypt
- Volunteers
- 66 people
- Sponsor
- Cairo University
Recovery
Comparison of Remimazolam With Flumazenil vs. Propofol During RFCA for Atrial Fibrillation
This prospective randomized trial aims to compare recovery time from discontinuation of remimazolam followed by flumazenil administration vs.
- Trial name
- NCT05397886
- Testing
- Remimazolam Besylate, Flumazenil, Propofol
- Where
- South Korea
- Volunteers
- 54 people
- Sponsor
- Seoul National University Hospital
Saccadic Eye Movements
The Effect of Sedation on Eye Movements
The purpose of this study is to determine whether sedation affects saccadic eye movements.
- Trial name
- Eye Movement (NCT00646646)
- Testing
- propofol, dexmedetomidine, Midazolam
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Pediatric Pateints, Amnesic Properties of Propofol
A Pilot Study to Assess the Amnesic Properties of Propofol in Pediatric Patients
The goal of this study is to extend findings of propofol's effects on memory, as measured in volunteer research studies, to a clinical setting.
- Trial name
- NCT02278003
- Testing
- memory test, Propofol
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Pediatric ALL
Propofol to Reduce the Incidence of Postanesthetic Emergence Agitation in Pediatric Patients Under General Anesthesia
This study aimed to know the effectivity of 0.5 mg/kg propofol in the end of anesthesia to reduce the incidence of postanesthetic emergence agitation in pediatric patients under general inhalation anesthesia
- Trial name
- NCT03528954
- Testing
- Propofol
- Where
- Indonesia
- Volunteers
- 54 people
- Sponsor
- Universitas Indonesia
Electroencephalography, Critical Care
Sedation Monitoring Using Frontal Electroencephalogram, Electromyogram and Hemodynamic Responses to Pain in Critical Care
Purpose: Assessing nociception and sedation in mechanically ventilated patients in the ICU is challenging, with few reliable methods available for continuous monitoring.
- Conditions
- Electroencephalography, Critical Care, Electromyography
- Trial name
- NCT04472247
- Testing
- Continuous EEG and EMG monitoring, with derived variables
- Where
- 2 sites in Finland
- Volunteers
- 30 people
- Sponsor
- University of Helsinki
Anesthesia
Intubation Conditions Achieved With Rapid Co-administration of Rocuronium and Propofol Versus Classical Induction
The purpose of this study is to assess and compare the conditions for tracheal intubation obtained with Modified Time Principle Induction (MTPI) and that obtained with classic induction (CI).
- Trial name
- NCT05509192
- Testing
- MTPI, Classic Induction
- Where
- United States
- Volunteers
- 154 people
- Sponsor
- The University of Texas Health Science Center, Houston
Chest Trauma With Ribs Fractures
PEF-Block & Ribs Fractures
Rib fractures are frequent injuries found approximately in 10% severe trauma patient. Rib fractures were correlated in many studies with a higher morbidity and mortality.
- Trial name
- PEF (NCT03396692)
- Testing
- Intravenous morphine patient-controlled analgesia (PCA), Block of the posterior exo-thoracic fascia with Ropivacaine, Block of paravertebral space with Ropivacaine
- Where
- France
- Volunteers
- 90 people
- Sponsor
- University Hospital, Montpellier
Ambulatory Surgery, Coughing
Effect of Fentanyl on Coughing and Recovery After Anesthesia With an LMA Laryngeal Mask Airway)for Airway Management
The purpose of this research is to evaluate the effectiveness of fentanyl for reducing coughing during the perioperative period (i.e., insertion of an LMA [Laryngeal Mask Airway] device, maintenance period during surgery, and…
- Trial name
- LMA (NCT01368809)
- Testing
- Saline, Fentanyl
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Cedars-Sinai Medical Center
Intravenous Anesthetic Agent Overdose
Propofol Pharmacokinetics and Pharmacodynamics Modelling
The main purpose of this research is to develop a population pharmacokinetic and pharmacodynamic model of Propofol when used for induction and maintenance of anaesthesia, using BIS as a pharmacodynamic endpoint.
- Trial name
- NCT02713698
- Testing
- Propofol
- Where
- Portugal
- Volunteers
- 60 people
- Sponsor
- Centro Hospitalar do Porto
Anesthesia, Anesthesia, Intravenous
Comparability of Invasive and Non-invasive Haemodynamic Monitoring
During general anesthesia the basic non-invasive monitoring of hemodynamic parameters (blood pressure, O2-saturation, cardiogram) is crucial.
- Trial name
- HMPR1 (NCT02197858)
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Mitral Valve Insufficiency, Aortic Valve Insufficiency
Influence of Anesthetics on Clinical Outcome in Mitral and Aortic Valve Replacement in Adults
Abstract Anaesthetic support for cardiac surgery significantly influences the course of the intraoperative period and the success of the postoperative period.
- Trial name
- NCT05696509
- Testing
- Propofol, Isoflurane, Sevoflurane
- Where
- Kazakhstan
- Volunteers
- 75 people
- Sponsor
- Astana Medical University
Injection Site
Efficacy of TEAS On Prevention of Propofol Injection Pain in Children
The purpose of this study is to determine the efficacy of transcutaneous electrical acupoint stimulation for the prevention of propofol injection pain in children.
- Trial name
- NCT05296187
- Testing
- TEAS
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Konya Meram State Hospital
Postoperative Pain, Acute, Emergence Delirium
Comparing Ketamine and Fentanyl in Pediatric Tonsillectomy: Pain Control and Emergence Delirium Outcomes (KVFPT)
This study is designed to compare the effectiveness of two medications, ketamine and fentanyl, in managing pain and preventing delirium in children aged 3 to 8 years who are undergoing tonsillectomy and adenoidectomy surgery.
- Trial name
- KVFPT (NCT06630364)
- Testing
- ketamine, fentanyl
- Where
- Turkey (Türkiye)
- Volunteers
- 59 people
- Sponsor
- Medipol University
Refractory Pains, End of Life Patients
Pilot Study of Sedation With Propofol in Refractory Pains Due to Care in Palliative Care Unit
In the palliative care unit, certain patients suffer from pain associated with medical procedures/care which is poorly controlled by antalgics.
- Trial name
- PROPOPAL1 (NCT02198404)
- Testing
- sedation with propofol
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Centre Hospitalier Universitaire de Nice