Clinical trials: Propranolol
Infantile Hemangioma
''Efficacy of Propranolol in the Treatment of Infantile Hemangioma"
''Evaluation of the Efficacy of Propranolol in the Treatment of Infantile Hemangioma"
- Trial name
- NCT04684667
- Testing
- Propranolol Therapy for Infantile Hemangioma
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
Schizophrenia, Schizoaffective Disorder
CLOZAPINE Response in Biotype-1
The CLOZAPINE study is designed as a multisite study across 5 sites and is a clinical trial, involving human participants who are prospectively assigned to an intervention.
- Conditions
- Schizophrenia, Schizoaffective Disorder, Bipolar 1 Disorder
- Trial name
- NCT04580134
- Testing
- clozapine, risperidone
- Where
- 5 sites in United States
- Volunteers
- 524 people
- Sponsor
- University of Texas Southwestern Medical Center
Gastrointestinal Tumors
The Use of Propranolol in the Perioperative Period of Resectable Gastrointestinal Tumors
In this study, perioperative propranolol β-blockade was administered to patients with surgically resectable primary gastrointestinal tumors to explore the safety, efficacy, and alleviation of perioperative psychological stress.
- Trial name
- NCT06775080
- Testing
- propranolol (beta-blocker used treat high blood pressure)
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Huashan Hospital
Migraine
Comparative Effectiveness of Migraine Preventive Medications: The APT Comparison Study
This goal of this study is to compare three medications used for migraine preventive treatment. This study will compare atogepant, a newer migraine preventive medication, with two older preventive medications, topiramate and…
- Trial name
- NCT06972056
- Testing
- Atogepant 60 mg, Propranolol 160 mg, Topiramate 100 mg
- Where
- 37 sites in United States
- Volunteers
- 1,335 people
- Sponsor
- Mayo Clinic
Arrhythmia, Cardiovascular Diseases
Beta-Blocker Heart Attack Trial (BHAT)
To determine whether the regular administration of the beta-blocker drug propranolol to people who had had at least one documented myocardial infarction would result in a significant reduction of mortality from all causes over…
- Conditions
- Arrhythmia, Cardiovascular Diseases, Coronary Disease, Death, Sudden, Cardiac
- Trial name
- NCT00000492
- Testing
- propranolol
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Obesity, Vasodilation
Sex Disparities in Hypoxic Vasodilation and Impact of Obesity
The purpose of this project is to examine key mechanisms contributing to sex-differences in hypoxic vasodilation and the impact of obesity, with particular emphasis on the sympathetic nervous system.
- Conditions
- Obesity, Vasodilation, Healthy
- Trial name
- NCT05219799
- Testing
- Propranolol Hydrochloride, Isoproterenol, Phentolamine Mesylate
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Epilepsy, Drug Resistant
Propranolol Adjuvant Treatment of Focal Refractory Epilepsy (PATFRE)
The aim of this study is to evaluate the clinical efficacy of propranolol as an adjunctive treatment for refractory epilepsy. The significance of this research lies in exploring whether propranolol, as an inhibitor of the…
- Trial name
- NCT06719804
- Testing
- Propranolol
- Volunteers
- 15 people
- Sponsor
- Xuanwu Hospital, Beijing
Hyperthyroidism, Graves Disease
Efficacy and Safety of Cholestyramine and Prednisolone as Adjunctive Therapy in Treatment of Overt Hyperthyroidism
Hyperthyroidism is the second most common endocrine disorder in the world with Graves' disease being the commonest. Anti thyroid drugs including methimazole, carbimazole, and propylthiouracil are effective treatments but take in…
- Trial name
- ChoPS (NCT03303053)
- Testing
- Cholestyramine Powder 4g, Prednisolone, Standard treatment
- Where
- 3 sites in Malaysia
- Volunteers
- 135 people
- Sponsor
- Clinical Research Centre, Malaysia
Chronic Migraine
NINDS CRC Chronic Migraine Treatment Trial
The purpose of this study is to compare the reduction in the number of severe headache days at six months in people with chronic migraine treated with topiramate and propranolol versus those treated with topiramate and a placebo.
- Trial name
- CMTT (NCT00772031)
- Testing
- propranolol LA, topiramate
- Where
- 39 sites in United States
- Volunteers
- 191 people, healthy volunteers welcome
- Sponsor
- Anne Lindblad
Idiopathic Ventricular Fibrillation, Cardiac Arrest, Out-Of-Hospital
MEdical Treatment in Idiopathic Ventricular Fibrillation Patients
A person who has experienced a cardiac arrest with no apparent cause is at risk of having recurrent cardiac arrest. Hence an implantable cardioverter-defibrillator (ICD) is recommended on empirical grounds.
- Trial name
- RIME-IVF (NCT07405229)
- Testing
- Beta-blocker treatment group
- Where
- 2 sites in Denmark
- Volunteers
- 218 people
- Sponsor
- Bo Gregers Winkel
Clinical Stage II Esophageal Adenocarcinoma AJCC v8, Clinical Stage III Esophageal Adenocarcinoma AJCC v8
Propranolol in Combination With Pembrolizumab and Standard Chemotherapy for the Treatment of Unresectable Locally Advanced or Metastatic Esophageal or Gastroesophageal Junction Adenocarcinoma
This phase II trial tests what effects the addition of propranolol to pembrolizumab and standard chemotherapy (mFOLFOX) may have on response to treatment in patients with esophageal or gastroesophageal junction cancer that cannot…
- Conditions
- Clinical Stage II Esophageal Adenocarcinoma AJCC v8, Clinical Stage III Esophageal Adenocarcinoma AJCC v8, Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8, Clinical Stage IV Esophageal Adenocarcinoma AJCC v8
- Trial name
- NCT05651594
- Testing
- Biopsy, Biospecimen Collection, Computed Tomography
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Roswell Park Cancer Institute
Tardive Dyskinesia
Safety and Efficacy of Propranolol in the Treatment of Tardive Dyskinesia
Tardive dyskinesia (TD) is a disabling, embarrassing and often irreversible iatrogenic movement disorder that can occur in anyone exposed to drugs that block dopamine receptors, including first and second generation…
- Trial name
- NCT03254186
- Testing
- Propranolol Hydrochloride
- Sponsor
- Emory University
Cirrhosis, Portal Hypertension
Danish Carvedilol Study in Portal Hypertension
Patients with large esophageal varices who have not yet experienced bleeding, are normally treated with propranolol, a beta blocking agent that reduces the portal pressure and thereby diminish the risk of bleeding.
- Trial name
- DACAPO (NCT00493480)
- Testing
- carvedilol, propranolol
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Hvidovre University Hospital
Induction of Labor Affected Fetus / Newborn
Propranolol Versus Placebo for Induction of Labor in Nulliparous Patients
A randomized, prospective trial will be offered to women admitted to the labor floors at Mount Sinai Medical Center for labor induction.
- Trial name
- NCT03348683
- Testing
- Propranolol
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Ivabradine, Propranolol
Efficacy of Ivabradine Versus Propranolol Premedication During Hypotensive Anesthesia in Endoscopic Sinus Surgery
50 Patients, aged from 18 to 39 years, ASA physical status I and II, undergoing endoscopic sinus surgery will be enrolled in the study.The patients will be randomly allocated by simple randomization using a computer programme…
- Conditions
- Ivabradine, Propranolol, Hypotensive Anesthesia
- Trial name
- NCT04208594
- Testing
- Ivabradine, Propranolol
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Alexandria University
Traumatic Brain Injury
Role of Combined Therapy of Propranolol and Gabapentin in Paroxysmal Sympathetic Hyperactivity in Traumatic Brain Injury
Paroxysmal sympathetic hyperactivity (PSH) is a syndrome that comprises a series of signs and symptoms reflecting exacerbated sympathetic activity, including arterial hypertension, fever, tachycardia, generalized perspiration…
- Trial name
- NCT05427474
- Testing
- Propranolol , gabapentin
- Where
- 2 sites in Egypt
- Volunteers
- 90 people
- Sponsor
- Zagazig University
Misophonia
Behavioral and Pharmacological Reconsolidation Interference in Misophonia
One of the core processes presumably underlying misophonia - a condition characterized by decreased tolerance for specific sounds - is associative learning.
- Trial name
- Miso Prop (NCT05928689)
- Testing
- Propranolol Hydrochloride tablet, Reminder, Counterconditioning
- Where
- United States
- Volunteers
- 141 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Pain Measurement
Evaluation of Propranolol's Effect on Pain and Inflammation.
Previous studies have shown that the beta-adrenergic system plays a role in processing pain and the expression of hyperalgesia. Recent studies have investigated the analgesic effects, and potential anti-hyperalgesic effects…
- Trial name
- NCT01094574
- Testing
- Alfentanil, Propranolol
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Martin Angst
Asthma
Beta Blocker Therapy in Mild to Moderate Asthmatics
Current asthma medicines include inhalers. A common type of inhaler is called a 'beta-agonist' (e.g. salbutamol). They improve asthma symptoms by stimulating areas in the airway causing it to widen.
- Trial name
- ANDA1 (NCT01544634)
- Testing
- Propranolol, Qvar 50, Qvar 100
- Where
- United Kingdom
- Volunteers
- 16 people
- Sponsor
- University of Dundee
Migraine Prophylaxis
Comparison of Propranolol, Flunarizine and Their Combination in Preventing Migraine in Adults in a Tertiary Care Hospital in Bangladesh
Migraine is a common and disabling neurological condition that affects quality of life, work productivity, and daily functioning.
- Trial name
- NCT07655700
- Testing
- Propranolol 80 mg, Flunarizine 10 mg, Propranolol 40 mg + Flunarizine 10mg
- Where
- Bangladesh
- Volunteers
- 177 people
- Sponsor
- Chittagong Medical College