Clinical trials: Propranolol
Cardiovascular Diseases, Heart Diseases
Reducing Total Cardiovascular Risk in an Urban Community
PLEASE NOTE: THIS STUDY IS ONLY ENROLLING PATIENTS CURRENTLY BEING TREATED AT BELAIR-EDISON FAMILY HEALTH CENTER. The purpose of this study is to compare the clinical effectiveness and cost effectiveness of two cardiovascular…
- Conditions
- Cardiovascular Diseases, Heart Diseases, Coronary Disease, Diabetes Mellitus
- Trial name
- COACH (NCT00241904)
- Testing
- Lifestyle Changes, Antiplatelet Agents, Beta Blocker
- Where
- United States
- Volunteers
- 525 people
- Sponsor
- Johns Hopkins University
Portal Hypertension
8mm-TIPS Versus Endoscopic Variceal Ligation (EVL) Plus Propranolol for Prevention of Variceal Rebleeding
The aim of this study was to conduct a prospective randomized trial to compare TIPS with 8mm expanded polytetrafluoroethylene(ePTFE)-covered stents and endoscopic variceal ligation plus propranolol for the prevention of recurrent…
- Trial name
- NCT02477384
- Testing
- 8mm-TIPS, Endoscopic variceal ligation, Propranolol
- Where
- China
- Volunteers
- 100 people
- Sponsor
- West China Hospital
Posttraumatic Stress Disorder
Reducing Reconsolidation of Trauma Memories With Propranolol
The purpose of this study is to test whether propranolol is capable of reducing subsequent physiological trauma-related conditioned responses, as well as self-reported post-traumatic stress disorder (PTSD) symptoms.
- Trial name
- NCT01349439
- Testing
- Propranolol, Short acting + long acting propranolol + memory reactivation
- Where
- Canada
- Volunteers
- 76 people
- Sponsor
- Douglas Mental Health University Institute
Cervical Cancer
Feasibility - Beta Adrenergic Blockade (BB) in Cervical Cancer (CX)
The goal of this clinical research study is to learn how many patients with advanced, recurrent, incurable cervical cancer will complete questionnaires about symptoms, any anxiety, depression, and/or pain, and the quality of…
- Trial name
- NCT01902966
- Testing
- Propranolol, Diary, Relaxation Audio Recording
- Where
- 2 sites in United States
- Volunteers
- 6 people
- Sponsor
- M.D. Anderson Cancer Center
Migraine, Common Migraine
A Study of the Efficacy and Safety of Two Doses of Topiramate Compared to Placebo and Propranolol in the Prevention of Migraine
The purpose of this study is to evaluate the safety and efficacy of two doses of topiramate (100 and 200 mg daily) versus placebo and propranolol in the prevention of migraine.
- Conditions
- Migraine, Common Migraine, Classic Migraine, Headache
- Trial name
- NCT00236561
- Testing
- topiramate, propranolol
- Volunteers
- 786 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Hepatic Cirrhosis, Portal Hypertension
The Treatment of Hepatocirrhosis and Portal Hypertension
This study compare the efficiency of partial splenic embolization +endoscopical therapy with endoscopical therapy alone in gastroesophageal variceal haemorrhage accompanied with splenomegaly or hypersplenism of hepatocirrhosis…
- Trial name
- NCT02778425
- Testing
- Endoscopic therapy+ beta blockers, Endoscopic therapy+ PSE+beta blockers, beta blockers
- Where
- China
- Volunteers
- 108 people
- Sponsor
- Yanjing Gao
Cirrhosis
Beta-blockers for Prevention Of Growth Of Small Esophageal Varices In Cirrhosis: An Randomized Controlled Trial (RCT)
Background and Aims: The efficacy of portal pressure reduction by beta blockers for the management of small (≤5 mm) esophageal varices in patients of cirrhosis is not clear.
- Trial name
- NCT00772057
- Testing
- Propranolol
- Where
- India
- Volunteers
- 164 people
- Sponsor
- Govind Ballabh Pant Hospital
Chronic Low-back Pain, Fibromyalgia
Reconsolidation Therapy With Propranolol as a Treatment for Chronic Pain
The primary aim of this study is to document the feasibility and acceptability of an intervention consisting of pain neuroscience education and reconsolidation therapy with propranolol in adults suffering from chronic pain…
- Trial name
- NCT05085782
- Testing
- Propranolol Hydrochloride, Reactivation procedure, Pain neuroscience education
- Where
- 2 sites in Canada
- Volunteers
- 48 people
- Sponsor
- Université de Sherbrooke
Cirrhosis, Variceal Bleeding
EBL Versus EBL and Propranolol for the Prevention of Variceal Rebleeding in Pts With Previous Variceal Treatment
This study is performed to compare the efficacy and safety of EBL alone and EBL combined with propranolol in patients who were previously performed endoscopic variceal treatment.
- Trial name
- NCT00966082
- Testing
- endoscopic band ligation, endoscopic band ligation+Propranolol
- Where
- South Korea
- Volunteers
- 180 people
- Sponsor
- Korea University
Migraine
Cognitive Side Effects of Commonly Prescribed Medications in Pediatric Migraine
The purpose of this study is to determine if there are significant differences in the side effects related to memory, repetition and recall among these three drugs when used in a pediatric population.
- Trial name
- NCT00777218
- Testing
- propranolol, zonisamide, topiramate
- Where
- United States
- Sponsor
- University of South Alabama
Cigarette Smoking
Neurobehavioral Substrates of Propranolol's Effects on Drug Cue Reactivity
The central objective of this project is to obtain proof-of-concept data demonstrating the effects of propranolol (a beta-adrenergic antagonist) on neurobiological responses to personal smoking environments and behavioral…
- Trial name
- ProCue (NCT03309943)
- Testing
- Propranolol
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Duke University
Cocaine Addiction
Enhancing Disrupted Reconsolidation: Impact on Cocaine Craving
The investigators' recently completed study has provided the first evidence that administration of the medication propranolol, following exposure to cocaine cues, can alter drug-associated memories and reduce craving and other…
- Trial name
- NCT01822587
- Testing
- Propranolol, 40 mg, Propranolol, 80 mg
- Where
- United States
- Volunteers
- 181 people
- Sponsor
- Medical University of South Carolina
Posttraumatic Stress Disorders
Propranolol Administration and Prevention of Child PTSD in Child Trauma Victims
Twenty-nine pediatric injury patients (ages 10-18) at risk for PTSD were randomly assigned to receive either propranolol or placebo in a double-blind placebo controlled design.
- Trial name
- NCT00597389
- Testing
- Inderol (propranolol)
- Volunteers
- 29 people
- Sponsor
- Kent State University
Hyperalgesia
Study on the Effect of a Beta Blocker on Increased Sensitivity to Pain in Humans Caused by Opioids
This research study explores whether a beta-blocker (propranolol) can prevent a person from becoming more sensitive to pain after administration of an opioid (remifentanil).
- Trial name
- NCT01222091
- Testing
- Propranolol, Remifentanil
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Stanford University
Hypotension
Ivabradine Versus Propranolol for Induced Hypotension in Endoscopic Sinus Surgery
the study is designed to compare the effect of addition of oral Ivabradine, propranolol to general anesthesia aimed reduction in blood loss during functional endoscopic sinus surgery.
- Trial name
- NCT04580342
- Testing
- oral Ivabradine, oral Propranolol
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ahmed talaat ahmed aly
Heroin Dependence, Learning and Memory
Effect of Stress on Heroin-Related Memory Retrieval
The purpose of this study is to determine whether cortisol and propranolol are effective in the modulation of stress induced heroin-related retrieval enhancement.
- Trial name
- NCT00759005
- Testing
- propranolol and cortisol
- Where
- China
- Sponsor
- National Institute on Drug Dependence, China
Migraine Associated Vertigo, Tinnitus
Comparing Migraine Preventive Therapies vs. Anti-CGRP Therapies for Tinnitus in Patients With Migraine (COMPACT-PM)
Many people with migraine also experience tinnitus - a persistent ringing, buzzing, or hissing in the ears - and research suggests these conditions share underlying biological mechanisms, including a protein called calcitonin…
- Conditions
- Migraine Associated Vertigo, Tinnitus, Migraine, Vestibular Migraine
- Trial name
- COMPACT-PM (NCT07655440)
- Testing
- Galcanezumab, Erenumab 70 mg, Eptinezumab
- Volunteers
- 120 people
- Sponsor
- Stanford University
Fibromyalgia Syndrome, Posttraumatic Stress Disorder
Impact of Post-Traumatic Stress Disorder Treatment by Reconsolidation Therapy on Fibromyalgia Syndrome
The aim of the study is to demonstrate a significant improvement in quality of life specific to patients with fibromyalgia syndrome in patients with fibromyalgia syndrome with comorbid posttraumatic stress disorder, treated with…
- Trial name
- PTSD-FMS (NCT04950426)
- Testing
- Propranolol
- Where
- 2 sites in France
- Volunteers
- 17 people
- Sponsor
- Centre Hospitalier Henri Laborit
To Determine Bioequivalence Under Fasting Conditions
Bioavailability Study of Propranolol Under Fasting Conditions
To compare the single-dose bioavailability of Propranolol 160 Mg ER capsules with Inderal-La
- Trial name
- NCT00653120
- Testing
- Propranolol, Inderal-LA
- Where
- Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Par Pharmaceutical, Inc.
Infantile Hemangioma (IH)
Abrupt Discontinuation Versus Gradual Tapering of Propranolol in Infantile Hemangioma
Infantile hemangioma is the most common benign vascular tumor in infancy. Oral propranolol is the first-line systemic treatment for infantile hemangiomas requiring therapy.
- Trial name
- PROIHSTOP (NCT07665177)
- Testing
- Abrupt Discontinuation of Propranolol, Gradual Tapering of Propranolol
- Where
- China
- Volunteers
- 110 people
- Sponsor
- West China Hospital