Clinical trials: Propranolol
Gastric Varix, Cirrhosis
EUS-guided Combined Therapy Versus Beta Blocker Therapy in Primary Prophylaxis o GOV II and IGV I
The EUS-guided combined therapy of coilingand 2-octyl-cyanoacrylate in patients with gastric varices reduced rebleeding and need for reintervention in comparison to EUS-guided coiling alone.The purpose of this study is to…
- Conditions
- Gastric Varix, Cirrhosis, GastroIntestinal Bleeding
- Trial name
- NCT04075760
- Testing
- Coils + Cyanoacrylate Group + beta-blocker, beta blocker therapy
- Where
- Ecuador
- Volunteers
- 26 people
- Sponsor
- Instituto Ecuatoriano de Enfermedades Digestivas
Kaposi Sarcoma
A Study of Propranolol to Treat Kaposi Sarcoma
A clinical study of propranolol for the treatment of Kaposi Sarcoma in children and adults. This study will be an open-label single armed treatment trial that will test the effectiveness and the safety of treating Kaposi Sarcoma…
- Trial name
- NCT05797662
- Testing
- Propranolol
- Where
- 6 sites in Argentina, Brazil and 3 more
- Volunteers
- 25 people
- Sponsor
- AIDS Malignancy Consortium
Induction of Labor Affected Fetus / Newborn
Propranolol and Misoprostol Versus Misoprostol Alone for Induction of Labor in Primigravidas
To compare propranolol and misoprostol versus misoprostol alone for induction of labour in primigravidas
- Trial name
- NCT04533841
- Testing
- Misoprostol, Propranolol
- Where
- Egypt
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Ahmed mohamed fathy ismail
Hyperthyroidism
Heart Rate Variability and Hyperthyroidism: Evaluation of the Short-term Effects of Propanolol
Objective: The aim of our study was to evaluate the short term effects of Propanolol on heart rate variability in patients with hyperthyroidism.
- Trial name
- NCT03393728
- Testing
- Propanolol
- Volunteers
- 10 people
- Sponsor
- Yaounde Central Hospital
Obsessive-compulsive Disorder
Brief Intervention for OCD Fears
The study will test the efficacy of propranolol or placebo, administered after reactivation of a previously acquired obsessive-compulsive disorder (OCD) fear, in reducing fear and avoidance in OCD.
- Trial name
- NCT02790710
- Testing
- Propanolol
- Where
- United States
- Sponsor
- New York State Psychiatric Institute
Cirrhosis, Hypertension, Portal
Efficacy of Statin Association With Standard Treatment in Prevention of Recurrent Hemorrhage in Patient With Cirrhosis and Variceal Bleeding
This is a prospective, double blind controlled trial in which patients with esophagic variceal bleeding treated with standard therapy (endoscopic variceal ligation(EVL) + B-blockers), will be randomized to receive statins or…
- Conditions
- Cirrhosis, Hypertension, Portal, Bleeding Esophageal Varices, Portal Vein Thrombosis
- Trial name
- NCT01095185
- Testing
- Simvastatin
- Where
- 15 sites in Spain
- Volunteers
- 150 people
- Sponsor
- Juan A. Arnaiz
DNA Damage, Psychological Stress
Brief Stresses Experimental Study
The goal of this study is to examine the impact of psychological stress on DNA integrity by conducting an experiment under controlled conditions with healthy volunteers to directly test the extent to which acute stress increases…
- Trial name
- NCT03893617
- Testing
- Propranolol, Acute stress task, No stress task
- Where
- United States
- Volunteers
- 239 people, healthy volunteers welcome
- Sponsor
- Dana Bovbjerg
Pediatric Migraine, Headache Disorders
Propranolol for Pediatric Migraine: A Prospective Clinical Study
This prospective, controlled clinical trial was conducted to evaluate the effectiveness of propranolol compared with structured behavioral therapy in pediatric patients diagnosed with primary migraine according to ICHD-3…
- Trial name
- NCT07180043
- Testing
- Structured Behavioral Therapy, Propranolol
- Where
- Turkey (Türkiye)
- Volunteers
- 178 people
- Sponsor
- Kayseri University
Cocaine-Related Disorders
Effectiveness of Amantadine and Propranolol for Treating Cocaine Dependence - 2
Cocaine addiction is a serious health problem with no available medical treatment for preventing relapse. Amantadine, a medication that improves muscle control, and propranolol, a medication that lowers blood pressure, may be…
- Trial name
- NCT00158132
- Testing
- Propranolol, Amantadine
- Where
- United States
- Volunteers
- 199 people
- Sponsor
- University of Pennsylvania
Obesity, Vasodilation
Sex Disparities in Hypoxic Vasodilation and Impact of Obesity
The purpose of this project is to examine key mechanisms contributing to sex-differences in hypoxic vasodilation and the impact of obesity, with particular emphasis on the sympathetic nervous system.
- Conditions
- Obesity, Vasodilation, Healthy
- Trial name
- NCT05219799
- Testing
- Propranolol Hydrochloride, Isoproterenol, Phentolamine Mesylate
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Long QT Syndrome, Cardiac Repolarization
Effect of Beta-blocker Therapy on QTc Response in Exercise and Recovery in Normal Subjects
Background. In congenital long QT syndrome type 1 (LQT1), episodes of ventricular tachycardia are usually triggered by exercise and can be prevented in most patients by beta-blocker therapy.
- Trial name
- NCT00588965
- Testing
- Propranolol LA
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- MetroHealth Medical Center
Traumatic Brain Injury (TBI) Patients
Efficacy of Propranolol in Traumatic Brain Injury Patients Admitted to the ICU: A Prospective, Randomized, Triple-Blind Study
Beta-blockers have shown promise as a treatment to improve patient prognosis following traumatic brain injury (TBI), although the exact mechanism by which they might confer this benefit remains unknown.
- Trial name
- ProP-TBI ICU (NCT07899164)
- Where
- 6 sites in Spain
- Volunteers
- 536 people
- Sponsor
- Fundació d'investigació Sanitària de les Illes Balears
Liver Cirrhosis, Portal Hypertension
Rifaximin and Propranolol Combination Therapy Versus Propranolol Monotherapy in Cirrhotic Patients
To reduce portal pressure, the only recommended medication is nonselective beta blocker(NSBB). However, NSBB has some limitation to apply clinically because of poor response rate and compliance.
- Trial name
- RECOVER (NCT01897051)
- Testing
- Rifaximin + propranolol
- Where
- 2 sites in South Korea
- Volunteers
- 140 people
- Sponsor
- Yonsei University
Migraine Headache, Gastric Diseases
Effect of "Sekanjabin e Safarjali" (Quince Oxymel) in the Prevention of Migraine Attacks
The purpose of this study is to determine whether Quince Oxymel is effective in the prevention of Migraine attacks in patients with simultaneous upper gastrointestinal dysfunction.
- Trial name
- NCT02179775
- Testing
- propranolol, Quince's oxymel
- Where
- 2 sites in Iran
- Volunteers
- 45 people
- Sponsor
- Shiraz University of Medical Sciences
Advanced Hepatocellular Carcinoma, Advanced Melanoma
Multiple Adjunct Therapies to Improve Immunotherapy Treatment in Patients With Locally Advanced or Metastatic Melanoma or Advanced Hepatocellular Cancer
This clinical trial tests the effect of multiple therapies (propranolol, desloratadine, and magnesium and vitamin D supplements) added to primary standard of care immunotherapy (adjunct), as well as adjusting the timing of…
- Conditions
- Advanced Hepatocellular Carcinoma, Advanced Melanoma, Locally Advanced Melanoma, Metastatic Melanoma
- Trial name
- NCT07836712
- Testing
- Biospecimen Collection, Cholecalciferol, Computed Tomography
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- University of Southern California
Migraine
Comparative Effectiveness of Migraine Preventive Medications: The APT Comparison Study
This goal of this study is to compare three medications used for migraine preventive treatment. This study will compare atogepant, a newer migraine preventive medication, with two older preventive medications, topiramate and…
- Trial name
- NCT06972056
- Testing
- Atogepant 60 mg, Propranolol 160 mg, Topiramate 100 mg
- Where
- 37 sites in United States
- Volunteers
- 1,335 people
- Sponsor
- Mayo Clinic
Akathisia, Drug-Induced, Antipsychotic Agents
Study of Preladenant for the Treatment of Neuroleptic Induced Akathisia (Study P05145)
This study is designed to evaluate the effectiveness of preladenant in the prevention (Part 1) or treatment (Part 2) of antipsychotic induced akathisia in participants with acute psychosis using the Barnes Akathisia Scale.
- Conditions
- Akathisia, Drug-Induced, Antipsychotic Agents, Movement Disorders
- Trial name
- NCT00693472
- Testing
- Preladenant, Anticholinergic agents or propanolol, Haloperidol
- Volunteers
- 46 people
- Sponsor
- Merck Sharp & Dohme LLC
Gastric Varices Bleeding, Endoscopic Ultrasound
Primary Prevention of Gastric Varices Bleed
Primary prophylaxis of gastric varices is an important area of research, as gastric varices are a common complication of cirrhosis of the liver.
- Trial name
- NCT05859009
- Testing
- EUS-Guided Therapy of Glue and Coil, Non-Selective Beta Blockers (Propanolol)
- Sponsor
- Unity Health Toronto
Infantile Haemangiomas
Systemic Propranolol for the Treatment of Paediatric Patients With Infantile Hemangiomas
This is retrospective study. The patients treated with oral propranolol at a dose of 2.0 mg/kg per day. Growth parameters (height and weight) were measured at the beginning, the end of treatment and 2 years after treatment.
- Trial name
- NCT04651049
- Testing
- propranolol
- Volunteers
- 128 people
- Sponsor
- Qilu Hospital of Shandong University
Tachycardia, Postural Orthostatic Tachycardia Syndrome
Pathophysiology of Orthostatic Intolerance
The purpose of this study is to describe the mechanism of orthostatic intolerance, relying on cardiovascular physiological studies.
- Trial name
- NCT00608725
- Testing
- DAXOR, QSweat, Intrinsic Heart Rate
- Where
- United States
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Satish R. Raj