Clinical trials: Propranolol
Fibromyalgia Pain
Propranolol for Treating Fibromyalgia Pain
The purpose of the study to evaluate the feasibility of using low dose propranolol for people with fibromyalgia.
- Trial name
- NCT03029845
- Testing
- Propranolol 1, Propranolol 2
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Utah
Healthy
In Vivo Specificity of KUC 7483 CL Co-administered With Bisoprolol, Propranolol, and Acipimox in Healthy Male Subjects
Study to compare the metabolic and electrolyte effects of a single oral dose of 320 mg ritobegron administered alone or with a pre- and comedication with bisoprolol, propranolol and acipimox.
- Trial name
- NCT02256722
- Testing
- KUC 7483 CL, Bisoprolol, Propranolol
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Infantile Hemangioma
Efficacy and Safety of Different Initial Doses of Oral Propranolol in the Treatment of Ulcerated Infantile Hemangioma
The main objective of this study was to determine the efficacy of different doses of propranolol in the treatment of ulcerattion infantile hemangioma (IH).
- Trial name
- NCT06798363
- Testing
- propranolol
- Where
- 3 sites in China
- Volunteers
- 32 people
- Sponsor
- West China Hospital
Arrest, Bone
Anabolic Steroid and Propranolol in Paediatric Burn
propranolol and anabolic steroids have a role in pediatric burn patients and their combined effects are to be studied here. They decrease the catabolic response to burn trauma and minimize the duration of growth arrest hence…
- Conditions
- Arrest, Bone, Development, Growth
- Trial name
- NCT05805553
- Testing
- Propranolol, Nandrolone Decanoate
- Where
- Pakistan
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- King Edward Medical University
Gastrointestinal Hemorrhage, Variceal Bleeding
Band Ligation Versus Transjugular Intrahepatic Portosystemic Stent Shunt (TIPS) in Cirrhotics With Recurrent Variceal Bleeding Non Responding to Medical Therapy
Patients with liver cirrhoses and recent history of variceal bleeding, with HVPG documented non response to medical therapy with non selective beta blockers +/- mononitrates or variceal rebleeding during adequate medical therapy…
- Conditions
- Gastrointestinal Hemorrhage, Variceal Bleeding, Cirrhosis, Encephalopathy
- Trial name
- ENDOvsTIPS (NCT00570973)
- Testing
- endoscopic band ligation, TIPS-Implantation
- Where
- 4 sites in Austria
- Volunteers
- 40 people
- Sponsor
- Medical University of Vienna
Hypertension
Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines (DREAM)- Propranolol/Carvedilol Versus Atenolol/Bisoprolol/Sotalol
This study aims to evaluate the comparative risk of dementia/Alzheimer's disease onset between patients treated with medications that target specific metabolic pathways and patients treated with alternative medications for the…
- Trial name
- NCT05794997
- Testing
- Propranolol or Carvedilol, Atenolol, Bisoprolol or Sotalol
- Where
- United States
- Volunteers
- 817,337 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Stroke, Vascular Accident
PROpranolol for Cerebral Hemorrhage-ASsociated pnEumonia (PRO-CHASE)
Stroke-associated pneumonia (SAP) is a grave complication of stroke and one of the most important predictors for patients' poor outcomes.
- Conditions
- Stroke, Vascular Accident, Intracranial Hemorrhages, Intracerebral Hemorrhage
- Trial name
- PRO-CHASE (NCT05419193)
- Testing
- Propranolol Hydrochloride, control group
- Where
- 12 sites in China
- Volunteers
- 168 people
- Sponsor
- Beijing Tiantan Hospital
Cocaine Addiction
Reducing Drug Craving Memories
The primary objective is to investigate the potential ability of Inderal (propranolol hydrochloride) to diminish the reconsolidation of motivationally potent drug-related cues in cocaine dependent participants.
- Trial name
- NCT01319214
- Testing
- Inderal
- Volunteers
- 60 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Healthy
Fasting Study of Propranolol Hydrochloride Extended-Release Capsules 160 mg and Inderal® LA Capsules 160 mg
The objective of this study was to investigate the bioequivalence of Mylan's propranolol hydrochloride extended-release 160 mg capsules to Wyeth's Inderal LA® 160 mg capsules following a single, oral 160 mg (1 x 160 mg) dose…
- Trial name
- NCT00647816
- Testing
- Propranolol Hydrochloride Extended-Release Capsules 160 mg, Inderal® LA Capsules 160 mg
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Mylan Pharmaceuticals Inc
Acute Kidney Injury, Cirrhosis
Impact of Nonselective Beta-blocker on Acute Kidney Injury in Cirrhotic Patients With Esophageal Varices
We will include patients with EV and EVB. They will be randomized to EVL vs. NSBB for primary prevention And EVL+long-term NSBB vs. EVL+short-term NSBB for secondary prevention. 150 patients will be included in a 3-year period.
- Conditions
- Acute Kidney Injury, Cirrhosis, Esophageal Varices
- Trial name
- AKI (NCT04074473)
- Testing
- propranolol, Esophageal varice ligation, DC propranolol
- Where
- Taiwan
- Volunteers
- 170 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Migraine
Zonisamide Versus Propranolol in Migraine
Investigators aim to compare the effect of zonisamide versus propranolol in migraine by assessing the absolute reduction in MMD in each group, the percentage of patients who achieved ≥ 50% reduction in the monthly headache days…
- Trial name
- NCT06361446
- Testing
- Zonisamide 50 MG, Propranolol
- Where
- Egypt
- Volunteers
- 600 people
- Sponsor
- Kafrelsheikh University
Healthy
Molecular Basis of Loss Aversion
The goal of this clinical trial is to test the roles of dopamine and norepinephrine in decision making related to loss aversion in the healthy population.
- Trial name
- NCT06034158
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sir Run Run Shaw Hospital
Temporomandibular Joint Disorders, Myofascial Temporomandibular Disorders
Effect of Propranolol on the Autonomic Nervous System and Muscle Pain
The project's primary purpose is to test the hypothesis that oral administration of a low single dose of β-antagonist propranolol (40 mg) reduces pain sensitivity in patients with masticatory muscle pain.
- Trial name
- NCT01333150
- Testing
- Propranololhydrochlorid
- Where
- 2 sites in Denmark
- Volunteers
- 16 people
- Sponsor
- University of Aarhus
Variceal Hemorrhage, TIPS
TIPS vs. NSBB Plus Endotherapy for the Prevention of Variceal Rebleeding in NSBB Non-responders of Primary Prophylaxis
Variceal bleeding (VB) is a life-threatening complication of cirrhosis with a 6-week mortality of approximately 15%-20%. The 1-year rate of recurrent VB is approximately 60% in patients without prophylaxis treatment.
- Conditions
- Variceal Hemorrhage, TIPS, NSBB, Liver Cirrhosis
- Trial name
- NCT04207398
- Testing
- Transjugular intrahepatic portosystemic shunts, Nonselective β-blocker (NSBB)+ endoscopic band ligation (EBL)
- Volunteers
- 114 people
- Sponsor
- Air Force Military Medical University, China
Stress Disorders, Traumatic, Acute
Propranolol for the Treatment of Acute Stress Disorder
This 10-week study will examine whether propranolol, a medication that blocks the activity of the stress hormones adrenaline and noradrenaline, can relieve acute stress disorder (ASD) and symptoms from persisting long-term.
- Trial name
- NCT00069355
- Testing
- Propranolol
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- National Institute of Mental Health (NIMH)
Parkinson Disease (PD), Tremor
A Study Comparing Propranolol and Amantadine for Reducing Tremors in People With Parkinson's Disease
Parkinson's disease is a common brain disorder in older adults that causes tremors (shaking), stiffness, and problems with movement.
- Trial name
- NCT07113015
- Testing
- propranolol, Amantadine
- Where
- Pakistan
- Volunteers
- 220 people
- Sponsor
- Multan Medical And Dental College
Misophonia
Behavioral and Pharmacological Reconsolidation Interference in Misophonia
One of the core processes presumably underlying misophonia - a condition characterized by decreased tolerance for specific sounds - is associative learning.
- Trial name
- Miso Prop (NCT05928689)
- Testing
- Propranolol Hydrochloride tablet, Reminder, Counterconditioning
- Where
- United States
- Volunteers
- 141 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Pregnancy, Prolonged
Propranolol Rescue of Prolonged Labor
A double-blind placebo controlled randomized trial comparing cesarean delivery rates in women given IV propranolol versus placebo for treatment of prolonged labor.
- Trial name
- PROPEL (NCT04299438)
- Testing
- Propranolol Hydrochloride, Saline
- Where
- 2 sites in United States
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Lisa Levine
Healthy
A Study of Continuous Heart Rate Monitoring in Healthy Participants
The main purpose of this study in healthy participants is to find out whether a heart rate monitor will accurately pick up changes in heart rate caused by 2 different medications (pseudoephedrine and metoprolol), on the…
- Trial name
- NCT04682184
- Testing
- Propranolol, Pseudoephedrine, Wearable Biosensor Patch Device
- Where
- Singapore
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Migraine Disorders
Tai Chi for the Prophylaxis of Episodic Migraine: the Efficacy Examination and Mechanism Exploration
The proposed study aims to examine the clinical efficacy of 24-week Tai Chi training in the prophylaxis of episodic migraine comparing with standard prophylactic medication in Hong Kong Chinese women, and to explore the mechanism…
- Trial name
- NCT05690737
- Testing
- Tai Chi training, Standard prophylactic medication
- Where
- 2 sites in Hong Kong
- Volunteers
- 220 people
- Sponsor
- The Hong Kong Polytechnic University