Clinical trials: Psilocybin, completed
Treatment Resistant Depression
The Safety and Efficacy Of Psilocybin as an Adjunctive Therapy in Participants With Treatment Resistant Depression
The Safety and Efficacy of Psilocybin as an Adjunctive Therapy in Participants with Treatment-Resistant Depression
- Trial name
- NCT04739865
- Testing
- Psilocybin
- Where
- 2 sites in United States, Ireland
- Volunteers
- 19 people
- Sponsor
- COMPASS Pathways
Functional Neurological Disorder
Psilocybin in Functional Neurological Disorder
The goal of this study is to learn about the brain network response in people who have functional neurological disorder who are administered with a single dose of the psychedelic psilocybin with therapeutic support.
- Trial name
- PsiFUND (NCT05723276)
- Testing
- Psilocybin
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- King's College London
Cancer
Study of Psilocybin Enhanced Group Psychotherapy in Patients With Cancer
This pilot project is an open-label trial that will offer psilocybin in a group format to assess the feasibility of offering psilocybin therapy in a group setting with a decreased therapist to subject ratio.
- Trial name
- HOPE (NCT04522804)
- Testing
- Psilocybin
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Utah
Treatment-resistant Depression
Does Psilocybin Require Psychedelic Effects to Treat Depression?
Psilocybin, the chemical component of "magic mushrooms", has been administered with psychotherapy in several randomized clinical trials (RCTs) showing large and sustained antidepressant effects.
- Trial name
- PSI-RIS (NCT05710237)
- Testing
- Psilocybin 25 mg, Risperidone 1 MG
- Where
- Canada
- Volunteers
- 41 people
- Sponsor
- Centre for Addiction and Mental Health
Migraine Headache
Repeat Dosing of Psilocybin in Migraine Headache
In seeking to understand the capacity for psilocybin to reduce migraine headache burden, this study will investigate single and repeated dosing of psilocybin up to two doses.
- Trial name
- NCT04218539
- Testing
- Psilocybin
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Yale University
Nicotine Dependence
Psilocybin-facilitated Smoking Cessation Treatment: A Pilot Study
One of the most promising lines of investigation for the therapeutic use of hallucinogens in the 1960s and 1970s was in the treatment of drug dependence.
- Trial name
- NCT01943994
- Testing
- Psilocybin-assisted treatment, Nicotine Replacement Therapy (NRT)
- Where
- 2 sites in United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Anorexia Nervosa
Psilocybin as a Treatment for Anorexia Nervosa: A Pilot Study
The primary aim of this study is to assess the acceptability and efficacy of treating anorexia nervosa with psilocybin. The secondary aim of this study is to use Magnetic Resonance Imaging (MRI) and Electroencephalography (EEG)…
- Trial name
- NCT04505189
- Testing
- Psilocybin
- Where
- United Kingdom
- Volunteers
- 21 people
- Sponsor
- Imperial College London
Treatment Resistant Depression, Suicidal Ideation
The Safety and Efficacy of Psilocybin in Patients With Treatment-resistant Depression and Chronic Suicidal Ideation
This study aims to explore the safety and tolerability of a single dose of psilocybin (25mg) administered under supportive conditions to adult participants with TRD and chronic suicidal ideation
- Trial name
- NCT05220410
- Testing
- Psilocybin
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Sheppard Pratt Health System
Anxiety
Effects of Psilocybin in Advanced-Stage Cancer Patients With Anxiety
Psychiatric Research Study For Cancer Patients The Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center is conducting a study designed to measure the effectiveness of the novel psychoactive medication…
- Trial name
- NCT00302744
- Testing
- Psilocybin (drug), Niacin, MRI
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Psychedelic Experiences
Safety for Home Administration of Microdose Psilocybin Use
The goal of this laboratory study is to establish whether and which microdoses of psilocybin are safe to administer at home to healthy participants.
- Trial name
- NCT06450210
- Testing
- psilocybin trihydrate
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Healthy
UW Psilocybin Pharmacokinetics Study
Psilocybin is a naturally occurring psychedelic compound produced by more than 200 species of mushrooms, collectively known as psilocybin mushrooms.
- Trial name
- NCT02163707
- Testing
- Psilocybin
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Healthy
Effects of Hallucinogens and Other Drugs on Mood and Performance
This non-treatment study will investigate the effects on mood and performance caused by hallucinogens and other psychoactive compounds.
- Trial name
- NCT02033707
- Testing
- Hallucinogens and psychoactive substances
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University