Clinical trials: Radiation, completed
Esophageal Squamous Cell Carcinoma
The Prognostic Value of Tertiary Lymphatic Structure in Esophageal Squamous Cell Carcinoma
Retrospective analysis of the presence and maturity of tertiary lymphoid structures in pathological sections of patients with esophageal squamous cell carcinoma after surgical treatment.
- Trial name
- NCT06241066
- Testing
- no-Intervention
- Where
- China
- Volunteers
- 359 people
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
Lung Cancer
Stereotactic Radiosurgery in Treating Patients Undergoing Chemotherapy and Radiation Therapy For Stage III Non-Small Cell Lung Cancer
RATIONALE: Drugs used in chemotherapy, such as docetaxel and cisplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Trial name
- NCT00945451
- Testing
- CK
- Where
- France
- Volunteers
- 35 people
- Sponsor
- Centre Antoine Lacassagne
Lung Cancer
3-Dimensional Conformal Radiation Therapy Versus Intensity Modulated Radiation Therapy
Primary Objective: Developing Common Toxicity Criteria (CTC) 3.0 grade > 3 treatment related pneumonitis (TRP) or Developing local-regional recurrence among patients treated with 3D conformal radiation therapy (CRT) (Arm 1) or…
- Trial name
- NCT00520702
- Testing
- Intensity Modulated Radiation Therapy, 3-Dimensional Conformal Radiation Therapy
- Where
- United States
- Volunteers
- 168 people
- Sponsor
- M.D. Anderson Cancer Center
Diabetes
Targeted Adherence Intervention to Reach Glycemic Control With Insulin Therapy for Patients With Diabetes
The purpose of this study is to evaluate three pharmacist-outreach strategies for improving adherence to insulin among individuals with diabetes.
- Trial name
- TARGIT-DM (NCT02846779)
- Testing
- Low intensity, Moderate intensity, High intensity
- Where
- United States
- Volunteers
- 6,000 people
- Sponsor
- Brigham and Women's Hospital
Effects of the Elements
Efficacy of Diode Laser in Maturogenesis of Immature Teeth With Necrotic Pulps
Recruited patients with immature permanent maxillary anterior teeth with non-vital pulp, and periapical radiolucency, age ranging from 8 to16 years old were randomly allocated into three groups (n=13): Group I, disinfected using…
- Trial name
- NCT05445362
- Testing
- Diode laser disinfection, Diode Laser bio-stimulation., Triple antibiotic paste disinfection
- Where
- Egypt
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Reham Hassan
Breast Cancer
Quadrant High Dose Rate Intraoperative Radiation Therapy (IORT) for Early-Stage Breast Cancer: A Pilot Study
This study was started to validate the possibility of administering radiation therapy during surgery to the tissue surrounding the tumor once the tumor has been removed.
- Trial name
- NCT00595062
- Testing
- Intra Operative Radiation Therapy (IORT)
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Solid Tumor, Adult
Basket Study of Leronlimab (PRO 140) in Patients With CCR5+ Locally Advanced or Metastatic Solid Tumors
A single arm phase II study with 30 patients of leronlimab (PRO 140) in patients with CCR5+ locally advanced or metastatic solid tumors.
- Trial name
- NCT04504942
- Testing
- Leronlimab
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- CytoDyn, Inc.
Halitosis
Evaluation of the Treatment of Halitosis With Photodynamic Therapy in Older Patients With Complete Denture
Halitosis is the term used to define an unpleasant odor emanating from the mouth. Some lung diseases and diabetes are among the extra-oral causes of this condition.
- Trial name
- NCT03960983
- Testing
- Treatment with tongue scraper, Hygiene procedures for the mucosa and dentures, Photodynamic Therapy
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Hodgkin´s Lymphoma
HD12 for Advanced Stages
This study is designed to test (1) whether the BEACOPP dosage can be reduced to baseline in the last 4 cycles without loss of effectiveness, and (2) whether consolidating irradiation is necessary following effective chemotherapy.
- Trial name
- NCT00265031
- Testing
- Cyclophosphamide, Adriamycin, Etoposide
- Sponsor
- University of Cologne
Breast Cancer
Intraoperative Radiation Therapy in Early Stage Breast Cancer
Single arm study to assess the effectiveness of single dose intraoperative radiation therapy in patient with in situ and early stage breast cancer.
- Trial name
- IORTBreast (NCT02266602)
- Testing
- Intraoperative Radiation Therapy
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Benaroya Research Institute
Esophageal Cancer
S0356 Oxaliplatin, 5-FU, Radiation Therapy (RT), Surgery for Pts With Stage II or III Cancer of Esophagus or Gastroesophageal (GE) Junction
RATIONALE: Drugs used in chemotherapy, such as oxaliplatin and fluorouracil, work in different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells.
- Trial name
- NCT00086996
- Testing
- fluorouracil, oxaliplatin, conventional surgery
- Where
- 143 sites in United States
- Volunteers
- 98 people
- Sponsor
- SWOG Cancer Research Network
Adolescent Idiopathic Scoliosis
Effect of a Brace on the Adolescent Idiopathic Scoliosis Breathing
This study intends to investigate the effect of bracing on respiratory function in the treatment of adolescent idiopathic scoliosis (AIS).
- Trial name
- CTM biomec (NCT05749562)
- Testing
- Cheneau-Toulouse-Munster brace
- Where
- France
- Volunteers
- 12 people
- Sponsor
- CHU de Reims
Non Hodgkin Lymphoma
RADVAX™ for Relapsed/Refractory Non-Hodgkin Lymphoma: A Phase II Trial of Pembrolizumab + Low Dose Radiotherapy
This study is an open-label Phase II trial of non-Hodgkin lymphoma patients receiving initial treatment with the immunomodulatory agent, pembrolizumab, plus low-dose (4 Gy x 5) involved-site radiotherapy.
- Trial name
- NCT04827862
- Testing
- Pembrolizumab
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Nasopharyngeal Carcinoma
Therapeutic Gain by Induction-concurrent Chemoradiotherapy and/or Accelerated Fractionation for Nasopharyngeal Carcinoma
The objectives of this clinical study are threefold: 1. To compare the benefits in cancer control and survival obtained from adding induction-concurrent chemotherapy to radiation with those from adding concurrent-adjuvant…
- Trial name
- NCT00379262
- Testing
- Capecitabine, Adjuvant chemotherapy using PF (5-Fluorouracil ), Induction chemotherapy using PF (5-Fluorouracil)
- Where
- 7 sites in China
- Volunteers
- 803 people
- Sponsor
- Hong Kong Nasopharyngeal Cancer Study Group Limited
Neoplasms, Second Primary
Secondary Cancer Risk After Radiation Therapy for Rectal Cancer
Retrospective study comparing dose distribution of 3D conformal radiotherapy (3DCRT) and volumetric-modulated arc therapy (VMAT) to estimate secondary cancer risk for patients having had radiation therapy for rectal cancer.
- Trial name
- NCT02572362
- Testing
- No intervention in this retrospective study
- Where
- Switzerland
- Volunteers
- 25 people
- Sponsor
- Kantonsspital Graubünden
Graft Versus Host Disease, Leukemia
Umbilical Cord Blood Transplantation in Treating Patients With Hematologic Cancer or Other Hematologic or Metabolic Diseases
RATIONALE: Umbilical cord blood transplantation may be able to replace cells destroyed by chemotherapy or radiation therapy. PURPOSE: Phase II trial to study the effectiveness of umbilical cord blood transplantation in treating…
- Conditions
- Graft Versus Host Disease, Leukemia, Myelodysplastic Syndromes, Thymic Carcinoma
- Trial name
- NCT00003662
- Testing
- anti-thymocyte globulin, busulfan, cyclophosphamide
- Where
- 15 sites in United States
- Volunteers
- 90 people
- Sponsor
- Roswell Park Cancer Institute
Acne, Atrophic Scar
Comparison of Picosecond Lasers vs. Ablative Fractional Er:YAG Lasers in Treating Atrophic Scar
The 1064-nm Nd:YAG picosecond lasers using fractional micro-lens array (P-MLA) was a promising therapy for skin resurfacing. However, no studies have compared P-MLA with ablative fractional 2940-nm Er:YAG lasers (AF-Er) in…
- Trial name
- NCT05686603
- Testing
- a fractional 1064-nm neodymium-doped yttrium aluminum garnet (Nd:YAG) picosecond laser with MLA handpiece, a ablative fractional 2940-nm Er:YAG laser
- Where
- China
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Ewing's Family Tumors, Renal Tumors
Auto Transplant for High Risk or Relapsed Solid or CNS Tumors
This is a standard of care treatment guideline for high risk or relapsed solid tumors or CNS tumors consisting of a busulfan, melphalan, thiotepa conditioning (for solid tumors) or carboplatin and thiotepa conditioning (for CNS…
- Conditions
- Ewing's Family Tumors, Renal Tumors, Hepatoblastoma, Rhabdomyosarcoma
- Trial name
- NCT01505569
- Testing
- Ifosfamide, Etoposide, Mesna
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Masonic Cancer Center, University of Minnesota
Head and Neck Cancer, Fibula Flap
Risk for Subsequent Osteoradionecrosis in A Transferred Fibula Flap in Head and Neck Cancer Patients Undergoing Segmental Mandibulectomy: a Cohort Study
A retrospective analysis of 329 patients at one single institution between January 2014 and December 2019 who underwent free fibula flap reconstruction was conducted.
- Conditions
- Head and Neck Cancer, Fibula Flap, Osteoradionecrosis, Mandibulectomy
- Trial name
- NCT06428994
- Testing
- Radiotherapy
- Where
- Taiwan
- Volunteers
- 580 people
- Sponsor
- Chang Gung Memorial Hospital
LC Pelvic Fracture
Pelvis RCT: Impact of Surgery on Pain in Lateral Compression Type Pelvic Fractures
Lateral compression type pelvic ring injuries remain the most common type of pelvic fractures encountered. There is a substantial amount of controversy surrounding the treatment of these injuries and there is evidence that both…
- Trial name
- NCT02625766
- Testing
- LC fracture surgical fixation, LC fracture non-operative management
- Where
- 2 sites in United States
- Volunteers
- 95 people
- Sponsor
- University of Maryland, Baltimore
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