Clinical trials: Radiation, completed
Metastatic Malignant Neoplasm in the Brain, Primary Brain Neoplasm
18F-FLT PET/CT in Measuring Cell Proliferation in Patients With Brain Tumors
This pilot clinical trial studies fluorine F 18 fluorothymidine (FLT) positron emission tomography (PET)/computed tomography (CT) in measuring cell proliferation in patients with brain tumors.
- Conditions
- Metastatic Malignant Neoplasm in the Brain, Primary Brain Neoplasm, Recurrent Brain Neoplasm
- Trial name
- NCT02167204
- Testing
- Computed Tomography, Fluorothymidine F-18, Positron Emission Tomography
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of Washington
Regenerative Endodontics
Regenerative Endodontics Using Different Intracanal Medicaments on Radiographic Outcomes and Periapical MMP-8 Levels
Two-session regenerative endodontic treatment was applied to 20 immature mandibular first molars with symptomatic irreversible pulpitis and symptomatic apical periodontitis.
- Trial name
- NCT05581706
- Testing
- Place the freshly prepared calcium hydroxide in to the root canals, Place the freshly prepared double antibiotic paste in to the root canals, Taking standart periapical radiography with film holder
- Where
- Turkey (Türkiye)
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Ege University
Prostate Cancer
A Pilot Study of Dose dE-eScalaTion IN prostATe radIOtherapy usiNg the MRL
Trial design: A single centre phase II non-randomised study Trial population: Men with intermediate risk localised prostate cancer Recruitment target: 20 patients in total Trial objectives: Primary To develop a 5 fraction…
- Trial name
- DESTINATION (NCT06284304)
- Testing
- De-escalated radiotherapy
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- The Netherlands Cancer Institute
Chronic Periodontitis
Evaluation of Antimicrobial Photodynamic Therapy in Multiple Applications as a Coadjuvant in the Surgical Therapy of Access to Scaling
Chronic periodontitis is an infectious disease resulting in inflammation of the teeth support structures, progressive periodontal attachment loss and bone loss.
- Trial name
- NCT03498404
- Testing
- Photodynamic Therapy, scaling and root planing
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
HIV Positive, Ageing
The Effects of Ageing on the 'Pharmacokinetic and Clinical Observations in People Over Fifty'
The purpose of this study is to identify medical conditions that may cause particular problems to individuals receiving care for HIV infection over the age of 50.
- Trial name
- POPPY (NCT01737047)
- Where
- 8 sites in Ireland, United Kingdom
- Volunteers
- 1,377 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Burning Mouth Syndrome
Effects of Photobiomodulation in Burning Mouth Syndrome
The main objective of this study is to assess the effects of Photobiomodulation with Low-level Laser Therapy to the pain management in Burning Mouth Syndrome patients, besides assessing their impact on the different aspects of…
- Trial name
- NCT04034849
- Testing
- Photobiomodulation
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Rosa María López-Pintor Muñoz
Immediate Implant Soft Tissue Healing
ASSESSMENT OF SOFT TISSUE HEALING OVER IMMEDIATELY PLACED IMPLANT SEALED WITH PLATELETS RICH FIBRIN (PRF) VERSUS DIODE LASER
Aim of the current study was to assess the efficacy of PRF in comparison to diode laser to promote tissue healing and soft tissue quality after placement of immediate implants.
- Trial name
- NCT05517733
- Testing
- Platelet Rich Fibrin, Diode laser
- Where
- Egypt
- Volunteers
- 16 people
- Sponsor
- Nourhan M.Aly
Uterine Cervical Neoplasms, Squamous Cell Carcinoma
The Potential for Metformin to Improve Tumor Oxygenation in Locally Advanced Cervix Cancer: A Phase II Randomized Trial
Cervical cancer remains an important health problem worldwide. Poor tumor oxygenation (hypoxia) is associated with inferior survival in cervical cancer and resistance to radiation treatment.
- Conditions
- Uterine Cervical Neoplasms, Squamous Cell Carcinoma, Adenocarcinoma, Carcinoma, Adenosquamous
- Trial name
- NCT02394652
- Testing
- Metformin, Cisplatin, FAZA
- Where
- 5 sites in Canada
- Volunteers
- 16 people
- Sponsor
- University Health Network, Toronto
Dysphagia, Dysphonia
Dysphagia and Dysphonia Outcomes in SARS CoV-2 (COVID-19) Infection (DYADS Study)
This study examines the presence, severity and natural history of dysphagia and dysphonia in the post-extubation and severely unwell COVID-19 patient.
- Conditions
- Dysphagia, Dysphonia, Subglottic Stenosis, Voice Disorders
- Trial name
- DYADS (NCT04584658)
- Testing
- Fibreoptic Endoscopic Evaluation of Swallowing (FEES), Videofluoroscopy, Dysphagia Handicap Index (DHI)
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Post -Partum Low Back Pain, Dynamic Neuromuscular Stabilization (DNS)
This Study Aimed to Evaluate the Effect of Dynamic Neuromuscular Stabilization (DNS) on Pain Intensity and Functional Disability in Women With PLBP as Common Problem Affect t he Women After Birth Which Often Impacting Their Quality of Life and Ability to Perform Daily Activities
The aim of this study was to determine the effect of DNS on women with post-partum LBP. Post-partum low back pain (PLBP) represents a prevalent and clinically significant condition that adversely impacts mobility, pelvic floor…
- Conditions
- Post -Partum Low Back Pain, Dynamic Neuromuscular Stabilization (DNS), Women's Health / Physiotherapy, Musculoskeletal Rehabilitation
- Trial name
- NCT07099755
- Testing
- Intervention Group: Name: Dynamic Neuromuscular Stabilization (DNS) Exercises, Control Group:Name: Conventional Physiotherapy (Ultrasound and Infrared Therapy)
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Gehad Alaa
Anxiety State
Intervention of a Game About Radiotherapy for Children With Cancer
Background: Radiotherapy (RT) can be stressful and challenging for children exposed to a highly technical environment with large radiation equipment and immobilization devices.
- Trial name
- NCT04728555
- Testing
- Game about radiotherapy
- Where
- Sweden
- Volunteers
- 22 people
- Sponsor
- Uppsala University
Rectal Cancer
The Predictive Value of Cytokines on Response to Preoperative Chemoradiotherapy in Patients With Rectal Cancer
Rationale and background: Predictive factors are needed to discriminate chemoradiotherapy responders from non-responders and to individualize the treatment regime.
- Trial name
- CYTORECT (NCT02077296)
- Where
- Netherlands
- Volunteers
- 34 people
- Sponsor
- St. Antonius Hospital
Breast Cancer, Radio Dermatitis
Autologous Fat Infiltration Versus General Measures as Treatment in Radiodermatitis Induced for Radiotherapy in Breast Cancer Patients
Radiodermatitis is a major problem in oncologic patients, fat grafts previously used for cosmetic procedures have been shown to have regenerative power due to their stem cell content.
- Conditions
- Breast Cancer, Radio Dermatitis, Radiotherapy
- Trial name
- NCT07023796
- Testing
- Autologous fat filtration
- Where
- Mexico
- Volunteers
- 22 people
- Sponsor
- Instituto Mexicano del Seguro Social
Head and Neck Cancer
Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Advanced Head and Neck Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells.
- Trial name
- NCT00003888
- Testing
- cisplatin, docetaxel, fluorouracil
- Where
- 44 sites in Austria, Belgium and 13 more
- Volunteers
- 359 people
- Sponsor
- European Organisation for Research and Treatment of Cancer - EORTC
Malignant Glioma
G207 Followed by Radiation Therapy in Malignant Glioma
This is an open-label, single site study to evaluate the safety and tolerability of intratumoral administration of G207 followed by treatment with radiation therapy in patients with recurrent/progressive malignant glioma.
- Trial name
- NCT00157703
- Testing
- G207
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- MediGene
Renal Cell Carcinoma
Stereotactic Radiotherapy and Anti-PD1 Antibody (Pembrolizumab) for Oligometastatic Renal Tumours
This investigator driven study will examine the safety, efficacy and biological effects of combining pembrolizumab (MK-3475) an antibody targeted against anti-programmed cell death 1 (PD-1), with stereotactic ablative body…
- Trial name
- RAPPORT (NCT02855203)
- Testing
- Stereotactic Ablative Body Radiosurgery (SABR), Pembrolizumab
- Where
- 2 sites in Australia
- Volunteers
- 30 people
- Sponsor
- Peter MacCallum Cancer Centre, Australia
Prolymphocytic Leukemia, Recurrent Adult Hodgkin Lymphoma
Autologous Stem Cell Transplant Followed by Donor Stem Cell Transplant in Treating Patients With Relapsed or Refractory Lymphoma
This phase I/II trial studies how well autologous stem cell transplant followed by donor stem cell transplant works in treating patients with lymphoma that has returned or does not respond to treatment.
- Conditions
- Prolymphocytic Leukemia, Recurrent Adult Hodgkin Lymphoma, Recurrent Childhood Hodgkin Lymphoma, Recurrent Childhood Non-Hodgkin Lymphoma
- Trial name
- NCT00005803
- Testing
- Autologous Hematopoietic Stem Cell Transplantation, Autologous-Allogeneic Tandem Hematopoietic Stem Cell Transplantation, Carmustine
- Where
- 5 sites in United States, Germany
- Volunteers
- 76 people
- Sponsor
- Fred Hutchinson Cancer Center
Spinal Cord Injury, Neuropathic Pain
Virtual Walking for Neuropathic Pain in Spinal Cord Injury
Spinal cord injury neuropathic pain (SCI-NP) is a common problem, and when severe, is one of the most problematic of secondary conditions that is minimally to modestly responsive to currently available treatments.
- Trial name
- NCT01884662
- Testing
- Virtual walking, Wheeling tape
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Healthy Volunteer
Radiolabeled Study of CC-220 in Healthy Male Subjects
This is a single-center, open-label study to characterize the biotransformation and excretion of [14C]-CC-220 in healthy male subjects.
- Trial name
- NCT03294603
- Testing
- CC-220, [14C]
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Celgene
Non-small Cell Lung Cancer
Analysis of Treatment Outcome and Toxicity in Non-small Cell Lung Cancer Patients Wither-irradiated to a High Dose for Recurrent Disease
As one of the few centers, MAASTRO also aggressively re-treats patients with recurrent non-small cell lung cancer. Even after primary radical treatment to high doses, re-irradiation (with concurrent chemotherapy) is also given in…
- Trial name
- NCT01941303
- Where
- Netherlands
- Volunteers
- 34 people
- Sponsor
- Maastricht Radiation Oncology
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