Clinical trials: Radiation, completed
Lung Cancer, Breast Cancer
DIBH Proton Planning
The overall objective is to estimate the actual or potential benefit of deep inspiration breath holding (DIBH) treatment in the context of proton radiotherapy as compared to 3 dimensional conformal radiation therapy (3DCRT) and…
- Conditions
- Lung Cancer, Breast Cancer, Gastrointestinal, Lymphomatous Malignancies
- Trial name
- NCT01386697
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Atherosclerosis of Coronary Artery, Cardiovascular Disease
Radiation Dose From Computed Tomography Before and After Implementation of a High Pitch Dual Spiral Technique
The purpose of this study is to compare the radiation exposure of a variety of chest CT examinations performed on the current state of the art CT scanners (64 slice, dual source CT scanner) with the radiation exposure for…
- Conditions
- Atherosclerosis of Coronary Artery, Cardiovascular Disease, Pulmonary Embolism, Aortic Aneurysm Without Mention of Rupture Nos
- Trial name
- FLASH (NCT01111760)
- Where
- United States
- Volunteers
- 334 people, healthy volunteers welcome
- Sponsor
- Michael Gallagher
Exposure of Member of Staff to Medical Diagnostic X-Ray
EffectivenesS of Additional X-ray PRotection dEviceS in Reducing Scattered Radiation in Radial interventiOn
This study evaluates the radiation exposure of scattered radiation for the interventionalist during coronary angiography using different X-ray protection materials, namely, an X-ray Screen without additional X-ray protection, an…
- Trial name
- ESPRESSO (NCT03634657)
- Testing
- Plain X-ray protection shield, Protection shield & X-ray protective strips, Protection shield & protective strips & patient cut-outs
- Where
- Germany
- Volunteers
- 700 people
- Sponsor
- Tommaso Gori
Polycystic Ovary Syndrome, Hypothalamic Amenorrhea
Body Fat as Determinant of Female Gonadal Dysfunction
Reproduction requires from women enough energy depots to warrant an adequate nutritional supply to the fetus. Hence, adipose tissue is able to communicate with female hypothalamic-pituitary-ovary axis.
- Trial name
- NCT03841981
- Testing
- Anthropometric and physical examination, Indirect calorimetry, accelerometer and seven-day dietary recall, Biochemical, hormonal and metabolic phenotyping
- Where
- Spain
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal
Leukemia
High-Intensity, Brief-Duration Chemotherapy in Treating Patients With Relapsed or Refractory Acute Lymphocytic Leukemia
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells.
- Trial name
- NCT00002865
- Testing
- filgrastim, cyclophosphamide, cytarabine
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Wake Forest University Health Sciences
Esophageal Cancer, Gastric Cancer
Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Esophageal Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells.
- Trial name
- NCT00005638
- Testing
- cisplatin, irinotecan hydrochloride, radiation therapy
- Where
- 2 sites in United States
- Sponsor
- Memorial Sloan Kettering Cancer Center
MGMT-unmethylated Glioblastoma (GBM), GBM
Nivolumab, Ipilimumab, and Short-course Radiotherapy in Adults With Newly Diagnosed, MGMT Unmethylated Glioblastoma
This is a single arm, open-label, phase II trial of nivolumab, ipilimumab and short-course radiation therapy in adult patients with newly diagnosed, MGMT unmethylated GBM with the primary objective of determining the overall…
- Trial name
- NCT03367715
- Testing
- Nivolumab, Ipilimumab, Radiation Therapy (RT)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- NYU Langone Health
Shoulder Pain, Stroke
SSNB in Hemiplegic Shoulder Pain
The purpose of this study is to compare suprascapular nerve block with therapeutic ultrasound in stroke patients who have shoulder pain in weak side.
- Trial name
- SSNB (NCT00732589)
- Testing
- 1% xylocaine, ultrasound
- Where
- Thailand
- Sponsor
- Chulalongkorn University
Carcinoma, Squamous Cell
Randomized Multicenter Study of 5 vs 6 Weekly Fraction of RT in the Treatment of SCC of the Head and Neck
Randomized multicenter study of 5 vs 6 weekly fraction of RT in the treatment of SCC of the head and neck
- Trial name
- NCT00534950
- Testing
- 5 vs 6 weekly fraction of RT
- Where
- Saudi Arabia
- Volunteers
- 200 people
- Sponsor
- King Faisal Specialist Hospital & Research Center
Orthodontic Treatment
Effect of Laser Application in Pain Management Following the Use of Orthodontic Elastomeric Separators
The aim of this study is to evaluate the effect of low level laser therapy (LLLT) on pain management in people commencing orthodontic treatment. The study design is a randomized controlled trial.
- Trial name
- NCT02209818
- Testing
- Laser Irradiation One dose, Laser Irradiation Two doses
- Where
- Syria
- Volunteers
- 72 people
- Sponsor
- Damascus University
Hodgkin's Lymphoma
Early Markers of Radiation-Induced Cardiac Injury in Hodgkin Lymphoma Treated With Radiation Therapy
The purpose of this study is to evaluate if radiation and chemotherapy treatment cause cardiac abnormalities among survivors of Hodgkin's lymphoma.
- Trial name
- NCT02404818
- Testing
- Cardiac Magnetic Resonance Imaging, Echocardiogram
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Florida
Lateral Epicondylitis
Dry Needling, Manipulation and Stretching vs. Manual Therapy, Exercise and Ultrasound for Lateral Epicondylalgia
The purpose of this research is to compare two different approaches for treating patients with lateral epicondylalgia: electric dry needling, thrust manipulation and stretching versus impairment-based manual therapy, exercise and…
- Trial name
- NCT03167710
- Testing
- Dry Needling, manipulation, stretching, manual therapy, exercise, ultrasound
- Where
- United States
- Volunteers
- 143 people
- Sponsor
- Alabama Physical Therapy & Acupuncture
Locally Advanced Rectal Cancer
Chemoradiation With Enadenotucirev as a Radiosensitiser in Locally Advanced Rectal Cancer
The use of chemoradiotherapy (CRT), in combination with surgery is the standard of care in the treatment of locally advanced rectal cancer. However some patients don't respond well to radiation.
- Trial name
- CEDAR (NCT03916510)
- Testing
- Enadenotucirev, Capecitabine, Radiotherapy
- Where
- 4 sites in United Kingdom
- Volunteers
- 12 people
- Sponsor
- University of Oxford
Breast Neoplasms
The Tomosynthesis Trial in Bergen - Part 2
The aim of the study is to compare early performance measures and economic aspects of organized breast cancer screening for women screened using digital breast tomosynthesis+synthetic mammography (DBT+SM) to women with a prior…
- Trial name
- To-Be 2 (NCT03669926)
- Testing
- Digital Breast Tomosynthesis+synthetic mammography
- Where
- Norway
- Volunteers
- 31,082 people, healthy volunteers welcome
- Sponsor
- Norwegian Institute of Public Health
NK/T-cell Lymphoma of Nasal Cavity
Concomitant Chemo-radiotherapy Plus VIDL Chemotherapy in NK/T-cell Lymphoma
This study is to evaluate the efficacy of risk-adapted treatment strategy for stage I/II extranodal NK/T cell lymphoma. The risk stratification is based on the Korean NK prognostic index.
- Trial name
- CCRT-VIDL (NCT01007526)
- Testing
- CCRT followed by VIDL chemotherapy
- Where
- South Korea
- Volunteers
- 31 people
- Sponsor
- Samsung Medical Center
Drug/Agent Toxicity by Tissue/Organ, Lung Cancer
Amifostine, Chemotherapy, and Radiation Therapy in Treating Patients With Limited-Stage Small Cell Lung Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells.
- Conditions
- Drug/Agent Toxicity by Tissue/Organ, Lung Cancer, Radiation Toxicity
- Trial name
- NCT00004176
- Testing
- amifostine trihydrate, cisplatin, etoposide
- Where
- 4 sites in United States
- Volunteers
- 34 people
- Sponsor
- Washington University School of Medicine
Head and Neck Cancer, Oral Mucositis
Ph 2 Open Label Study of GC4419 to Reduce SOM Associated With Chemoradiotherapy for Head and Neck Cancer
GTI-4419-202 is a Phase 2 open-label study of the effects of GC4419 (IV) when administered in combination with IMRT and cisplatin to up to subjects with head and neck cancer, who are at high risk for Severe Oral Mucositis (SOM)
- Trial name
- NCT04529850
- Testing
- Drug: GC4419, Intensity-modulated radiation therapy (IMRT), Cisplatin
- Where
- 24 sites in Belgium, Czechia and 4 more
- Volunteers
- 38 people
- Sponsor
- Galera Therapeutics, Inc.
Renal Failure, Kidney Donors
BOne Dysfunction in Donor NEphrectomieS
Most dialysis patients die from vascular disease, which is statistically associated with changes related to chronic kidney disease associated mineral bone disorder (CKD-MBD)3-9.
- Trial name
- BONES (NCT04674397)
- Testing
- Radioisotope GFR test
- Where
- United Kingdom
- Volunteers
- 34 people
- Sponsor
- Manchester University NHS Foundation Trust
Postoperative Hypoparathyroidism, Thyroid Disease
Assessing Benefits of NIRAF Detection for Identifying Parathyroid Glands During Total Thyroidectomy
This study describes a single center, randomized, single-blinded clinical trial to assess the clinical benefits of the use of near infrared autofluorescence (NIRAF) detection with an FDA-cleared device 'Parathyroid Eye (PTeye)'…
- Conditions
- Postoperative Hypoparathyroidism, Thyroid Disease, Thyroid Neoplasms, Thyroid Cancer
- Trial name
- NCT05579782
- Testing
- NIRAF Detection Technology
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Diabetic Retinopathy, Diabetic Macular Edema
Efficacy Study of Lucentis in the Treatment of Diabetic Macular Edema
This study will evaluate the clinical efficacy of intra-vitreal injections of Ranibizumab (Lucentis) in the treatment of Diabetic Macular Edema as compared to grid/focal laser.
- Trial name
- NCT00387582
- Testing
- Ranibizumab (Lucentis), Argon Laser
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Rocky Mountain Retina Consultants
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