Clinical trials: Remifentanil
Post-operative Nausea, Post-operative Vomiting
Study of Anesthesia Techniques to Reduce Nausea and Vomiting After Jaw Corrective Surgery
The purpose of this study is to determine whether a multi-modal anesthesia and pain control protocol reduces post-operative and post-discharge nausea and vomiting (PONV and PDNV) in patients undergoing upper jaw corrective…
- Conditions
- Post-operative Nausea, Post-operative Vomiting, Nausea Persistent
- Trial name
- NCT01592708
- Testing
- Antiemetic anesthesia protocol
- Where
- United States
- Volunteers
- 233 people
- Sponsor
- University of North Carolina, Chapel Hill
Cardiac Surgery
Remifentanil Versus Dexmedetomidine for Post-Cardiac Surgery Patients With Noninvasive Ventilation Intolerance
The aim of this study is to compare the sedation effects between remifentanil and dexmedetomidine in post-cardiac surgical patients who developed noninvasive ventilation (NIV) intolerance.
- Trial name
- REDNIVIN (NCT03395886)
- Testing
- Remifentanil, Dexmedetomidine
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Shanghai Zhongshan Hospital
Postoperative Nausea and Vomiting
Real-time Decision Support for Postoperative Nausea and Vomiting (PONV) Prophylaxis
The purpose of this study is to determine how automated recommendations are best presented to optimize the adherence to guidelines on prophylaxis for nausea and vomiting after surgery.
- Trial name
- NCT02625181
- Testing
- Automated recommendation at the start of the case, Automated notification at the start of surgery, Preoperative recommendations: by email
- Where
- United States
- Volunteers
- 27,034 people
- Sponsor
- Vanderbilt University
Hypercapnia
Improved Patient Recovery After Anesthesia With Hypercapnia Hyperpnoea
The proposed study will measure the time from the end of surgery until the time patients meet the discharge criteria from the postoperative anesthesia care unit and the time from the end of surgery until the patients regained…
- Trial name
- NCT00708526
- Testing
- standard of care for phase one anesthesia care, Quick Emergence Device
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Utah
Heart Diseases, Hyperglycemia
Remifentanil and Glycemic Response in Cardiac Surgery
This study evaluates the effect of using remifentanil during cardiopulmonary bypass surgery to supress the hyperglycemic response in perioperative period.
- Trial name
- NCT02349152
- Testing
- Remifentanil, Fentanyl
- Where
- United States
- Volunteers
- 116 people
- Sponsor
- Kathirvel Subramaniam
Delirium, Emergence Delirium
EEG - Guided Anesthetic Care and Postoperative Delirium
The study is a prospective, double blinded, randomized and controlled parallel trial to investigate the effect of the anesthetic care guided by EEG monitor (SedLine) on postoperative delirium.
- Conditions
- Delirium, Emergence Delirium, Anesthesia, General, Electroencephalography
- Trial name
- EMODIPOD (NCT03330236)
- Testing
- Anesthetic "depth" management
- Where
- China
- Volunteers
- 1,560 people
- Sponsor
- Yale University
Deep Extubation
Comparison of Deep Extubation During Emergence Using Desflurane or Desflurane With Remifentanil in Patients Undergoing General Anesthesia
It has been reported that deep extubation can reduce cardiopulmonary complication against endotracheal tube extubation during emergence from general anesthesia.
- Trial name
- NCT01924871
- Testing
- Desflurane with remifentanil, Desflurane
- Where
- South Korea
- Volunteers
- 62 people
- Sponsor
- Chung-Ang University Hospital
Muscle Relaxation
Effect of Deep Neuromuscular Block (NMB), Inhalation or TIVA on Pneumoperitoneum.
The objective of this study is to compare the value of deep neuromuscular block (NMB) (using rocuronium) in laparoscopy versus high dose opioids (using remifentanil) or 1 minimum alveolar concentration (MAC) inhalation (using…
- Trial name
- TIVA (NCT01930747)
- Testing
- rocuronium, Sevoflurane, remifentanyl
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- AZ Sint-Jan AV
Anterior Cervical Discectomy and Fusion (ACDF)
Narcotic Free TIVA and Incidence of Unacceptable Movements Under Anesthesia During ACDF Surgery
This study will help the investigators learn more about the best way to give anesthesia for these kinds of surgery. The investigators will be using 2 different groups of medications that is commonly used in ACDF surgery, one…
- Trial name
- NCT03643796
- Testing
- Remifentanil, Ketamine, Dexmedetomidine
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of Arkansas
Brain, Sedation
Deep Brain Stimulation (DBS) Sedation
Deep brain stimulation (DBS) of different brain nuclei is a treatment for multiple brain disorders. The subthalamic nucleus (STN) and globus pallidus have been used to treat advanced Parkinson's disease for a long time.
- Trial name
- NCT03283150
- Testing
- Remifentanil, Propofol, Dexmedetomidine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Wisconsin, Madison
Postoperative Pain
Optimal Sevoflurane Concentration for Intubation in Combination of Clincal Remifentanil Doses
Intubation is a procedure that requires well relaxed muscles while general anesthesia is performed. In order to get adequate muscle relaxation, remifentanil, sevoflurane or both agents in combination have been reported as they…
- Trial name
- NCT02440204
- Testing
- Intubation, Remifentanil, Sevoflurane
- Where
- South Korea
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Severance Hospital
Delayed Emergence From Anesthesia
Recovery Profile Comparison Between Remifentanil-propofol or Desflurane Anesthesia Monitored With Bispectral Index.
Bispectral monitoring anesthesia with remifentanil-desflurane has a better post-operative recovery than remifentanil-propofol.
- Trial name
- NCT02631525
- Testing
- Desflurane, Propofol
- Volunteers
- 40 people
- Sponsor
- Federal University of Minas Gerais
Sleep Apnea, Obstructive
Study of Pain Processing in Subjects Suffering From Obstructive Sleep Apnea
We would like to test the effect of opioid medication on pain sensitivity in subjects who have been diagnosed with a sleep disorder called Obstructive Sleep Apnea (OSA) compared to other subjects without OSA.
- Trial name
- NCT00672737
- Testing
- Remifentanil, Cold pain threshold and tolerance, Heat pain threshold and tolerance
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Stanford University
Pain, Anesthesia
Effect of Dexmedetomidine Combined With Low-dose Nalmefene on Preventing Remifentanil-induced Postoperative Hyperalgesia
To explore and compare antihyperalgesic effects of Dexmedetomidine,Nalmefene,and a combination of both received before anesthesia induction.
- Trial name
- NCT03096730
- Testing
- Normal saline, Remifentanil, Sufentanil
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Tianjin Medical University General Hospital
Anesthesia
Improving Information Extraction From EEG on Cerebral Anesthetic Drug Effects
This is an interventional, randomized controlled study in health volunteers that involves collecting data on raw EEG waves measuring various combinations of anesthetic drugs during standardized drug titration.
- Trial name
- NCT02043938
- Testing
- SedLine EEG sensor
- Where
- Netherlands
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Masimo Corporation
Diagnostic Colonoscopy Screening
Remifentanil Only vs. Midazolam and Meperidine During Elective Colonoscopy
The aim of the present study is to compare patient's recovery times after elective colonoscopy employing remifentanil only vs conventional combination of midazolam and meperidine
- Trial name
- remifentanil (NCT01693185)
- Testing
- Remifentanil, Midazolam, Meperidine
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Konkuk University Medical Center
Toxicity, Hydrocephalus
Isoflurane-induced Neuroinflammation in Children With Hydrocephalus
The investigators will quantify inflammatory biomarkers in cerebrospinal fluid (CSF) and serum of children with hydrocephalus who are undergoing ventriculoperitoneal shunt placement under isoflurane anesthesia.
- Trial name
- NCT02512809
- Testing
- Isoflurane, Dexmedetomidine
- Volunteers
- 25 people
- Sponsor
- Nationwide Children's Hospital
Opioid Toxicity, Pupillary Miosis
Pupillary Unrest as an Indicator of Central Opioid Effect in Subjects 40-60 Years of Age
This study will establish the relationship between magnitude of opioid exposure and a pupillary measure referred to as PUAL (pupillary unrest in ambient light), in subjects aged 40-60.
- Conditions
- Opioid Toxicity, Pupillary Miosis, Respiratory Depression
- Trial name
- NCT05391555
- Testing
- Remifentanil Hydrochloride, Pupillometry measurement
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Pain, Postoperative
Intraoperative Methadone Administration for Improved Pain Control in Spinal Fusion Patients
Methadone has several advantages over standard narcotic medications, especially when considering use after a typically painful surgery such as lumbar fusion.
- Trial name
- MAPS (NCT02989597)
- Testing
- Methadone Hydrochloride, Standard pain regimen, Spinal Fusion Surgery
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Osteoarthritis
General or Regional Anesthesia for Hip Surgery
The purpose of this study is to determine whether general anaesthesia or regional anaesthesia is best for patients undergoing Total Hip Arthroplasty.
- Trial name
- NCT01733472
- Testing
- GA-arm, remifentanil, RA-arm
- Where
- Sweden
- Volunteers
- 120 people
- Sponsor
- Region Skane