Clinical trials: Remifentanil
Anesthesia, Postoperative Pain
Opioid-free Anesthesia and Acute Postoperative Pain
Control of intraoperative and postoperative pain with the use of opioids constitutes normal practice. Opioid free anesthesia (OFA) is a relatively recent anesthesiology practice according to which opioids are not administered…
- Conditions
- Anesthesia, Postoperative Pain, Cognitive Impairment, Variable
- Trial name
- NCT04976842
- Testing
- OFA, OBA
- Where
- Greece
- Volunteers
- 200 people
- Sponsor
- Attikon Hospital
Optic Nerve Sheath
The Effect of Pnemoperitoneum on Intracranial Pressure and Cerebral Oxygenation During Laparoscopic Surgery According to Anesthesia Agents: Propofol Based Total Intravenous Anesthesia vs Desflurane Anesthesia
The pneumoperitoneum during laparoscopic surgery have the potential to cause an increase of intracranial pressure (ICP). Previous studies have proposed that ultrasonographic measurements of the optic nerve sheath diameter (ONSD)…
- Trial name
- NCT02003768
- Testing
- Propofol, Desflurane
- Sponsor
- Yonsei University
Spinal Stenosis
Effect of Nicardipine on Renal Function in Deliberate Hypotension
The aim of this study was to demonstrate the effect of nicardipine on renal function with creatinine clearance, serum cystatin C, urine output and fractional excretion of sodium during deliberate hypotension for spine surgery.
- Trial name
- NCT02271191
- Testing
- Nicardipine
- Volunteers
- 64 people
- Sponsor
- Yonsei University
Rhinoplasty Surgery
Effects of Dexmetomidine and Remifentanil Used for Controlled Hypotension in Septorhinoplasty Surgery on Cardiac Electrophysiology: Prospective Randomized Study
Our aim in this treatment was to reveal the effects of remifentanil and dexmetomidine, which we used to provide controlled hypotension in septorhinoplasty surgery, on cardiac electrophysiology.
- Trial name
- Effects of Dex (NCT06138574)
- Testing
- Dexmedetomidine, Remifentanil
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Postoperative Delirium, Gastrointestinal Tumors
Opioid-free Anesthesia and Postoperative Delirium
Postoperative delirium (POD) is a common acute and transient form of brain dysfunction in elderly patients following surgery that can lead to serious adverse clinical outcomes and even death.
- Trial name
- NCT07603596
- Testing
- OFA group, OBA group
- Volunteers
- 174 people
- Sponsor
- Qianfoshan Hospital
Spinal Stenosis Lumbar
Effect of Paravertebral Muscle Fat Infiltration on Rocuronium Use in Lumbar Surgery
To investigate the effect of different degrees of fat infiltration on rocuronium use in lumbar surgery was monitored by trapezius muscle relaxation.
- Trial name
- RUILS (NCT05619848)
- Testing
- Rocuronium Bromide
- Where
- China
- Volunteers
- 87 people
- Sponsor
- Zheng Guo
Anesthesia, General
Target-controlled Infusion of Propofol and Remifentanil During General Anaesthesia Guided by Entropy
This study compares the manual administration of propofol and remifentanil and their delivery using a combined closed-loop anesthesia system, entropy of the EEG being the controller.
- Trial name
- NCT00391885
- Testing
- Closed-loop anesthesia system
- Where
- 2 sites in France
- Volunteers
- 60 people
- Sponsor
- Hopital Foch
Anesthesia
The Comparability of Bispectral Index and Neurosense During Anesthesia
The assessment of anesthesia depth was based, until recently, on the evolution of hemodynamic parameters. Nowadays it can be evaluated by several monitoring methods, derived from electroencephalogram analysis, namely the…
- Trial name
- NCT00910416
- Testing
- propofol, remifentanil, atracurium, propofol, remifentanil, atracurium, sevoflurane, EEG monitoring
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Hopital Foch
Liver Disease
Propofol and Remifentanyl Versus Midazolam and Fentanyl for Diagnostic Colonoscopy in Patients With Compensated Cirrhosis Child A-B
This is a prospective, randomized-controlled trial (RCT) comparing the use of Propofol and Remifentanyl and traditional sedation (Midazolam and Fentanyl) for diagnostic colonoscopies in patients with compensated cirrhosis child…
- Trial name
- NCT01148277
- Testing
- Propofol and Remifentnyl, midazolam and fentanyl, midazolam anf fentanyl
- Where
- Israel
- Volunteers
- 90 people
- Sponsor
- Ziv Hospital
Intubation; Difficult or Failed, Obesity
The Role of Anthropometric Measurements and Ultrasonograpic Suprasternal Adipose Tissue Thickness
Prediction of difficult preoperative intubation in obese patients and completion of preparations for difficult intubation both reduce the risk of repeated intubation and prevent complications.
- Conditions
- Intubation; Difficult or Failed, Obesity, Anesthesia
- Trial name
- NCT06457165
- Testing
- Difficult Intubation, Not Difficult Intubation
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Ankara City Hospital Bilkent
Anesthesia, General
Automated Anesthesia During Bronchoscopy
The purpose of this study is to compare manual administration of propofol and remifentanil and dual closed-loop using bispectral index as the control variable during rigid bronchoscopy.
- Trial name
- NCT00571181
- Testing
- Closed-loop system, TCI (Infusion Toolbox)
- Where
- France
- Volunteers
- 66 people
- Sponsor
- Hopital Foch
Tracheal Intubation Morbidity, Pain
Prediction of Hemodynamic Response to Intubation by ANI Variation During Standardized Stimulation
The objective : to investigate a correlation between ANI following a standardized nociceptive stimulus and hemodynamic or somatic reactions during orotracheal intubation. Piloted study.
- Trial name
- ANI_LARYNGO (NCT04354311)
- Testing
- ANI
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Lille
Bronchoscopy
Remifentanil Plus Ketamine for Dynamic Flexible Bronchoscopy
This randomized controlled pilot clinical trial will enroll patients undergoing dynamic flexible bronchoscopy will be randomized to receive one of the two anesthetic combinations described above.
- Trial name
- NCT03613792
- Testing
- Remifentanil, Fentanyl, Midazolam
- Where
- United States
- Sponsor
- Beth Israel Deaconess Medical Center
General Anesthesia With Propofol, Closed-Loop
Feasibility of Closed-loop TCI Based on New EEG Baseline in the Presence of Low Dose of Esketamine
The propofol-remifentanil closed-loop TCI system based on EEG guidance has been clinically verified, which enables more precise anesthetic dosing.
- Trial name
- NCT06729892
- Testing
- Esketamine at low dose, new BIS baseline, an equivalent dose of saline
- Volunteers
- 120 people
- Sponsor
- bo xu
Magnesium Sulfate, Postoperative Pain
Opioid Sparing General Venous Anesthesia With Magnesium Sulfate
Magnesium sulfate has been shown to be useful in many situations in medicine, such as eclampsia prevention and treatment, pulmonary hypertension, arterial pressure, asthma, cardiac arrhythmias and pheochromocytoma.
- Conditions
- Magnesium Sulfate, Postoperative Pain, Opioid Use
- Trial name
- NCT04005599
- Testing
- Remifentanil group, Magnesium sulfate group
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- University of Sao Paulo General Hospital
Overactive Bladder
Evaluation of Efficacy and Patient Satisfaction of Local Anaesthesia Versus Sedoanalgesia for Botox (R) Injection in the Urinary Bladder for the Treatment of Idiopathic Overactive Bladder
Patients with symptoms of overactive bladder suffer from frequent micturition, urinary incontinence and recurrent urinary tract infections.
- Trial name
- LA vs SA (NCT06437899)
- Testing
- intravesical botulinum toxin A injection unter local anaesthesia
- Where
- Austria
- Volunteers
- 84 people
- Sponsor
- Hospital LKH Hochsteiermark - Leoben
Sleep Disorder, Sleep, Inadequate
Measuring Sleep Quality In Patients That Posterior Spinal Instrumentatıon Plannıng
Postoperative sleep disorders have serious problems with cognition, pain perception, sustained circadian rhythm, psychomotor function, metabolic function, catabolic responses, and continuity.
- Conditions
- Sleep Disorder, Sleep, Inadequate, Total ıntravenous Anesthesia, Inhalation Anesthesia
- Trial name
- NCT06269328
- Testing
- Total ıntravenous anesthesia with propofol and remifentanil for anesthetic maintenance, Inhalation anesthesia with sevoflurane for anesthetic maintenance
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Uludag University
Magnesium Sulfate, Remifentanil
Anesthesia Techniques, Neuroprotection and Surgical Field in FESS Under Controlled Hypotension
This prospective, randomized controlled trial investigates the effect of four different anesthetic maintenance techniques on surgical field conditions, hemodynamic stability, and neuroprotection during functional endoscopic sinus…
- Conditions
- Magnesium Sulfate, Remifentanil, S 100beta, S100 Beta Protein, Human
- Trial name
- NCT07181564
- Testing
- Propofol / Remifentanil, Ketamine + Magnesium sulfate (drug combination), Sevoflurane and Remifentanil
- Where
- Greece
- Volunteers
- 150 people
- Sponsor
- University General Hospital of Patras
Patients Undergoing Laparoscopic Gastrectomy
Effect of Nefopam on Remifentanil Induced Postoperative Hyperalgesia
Opioids has been reported to cause hyperalgesia. Opioid induced hyperalgesia (OIH) is defined as paradoxically lowering the threshold of pain after the exposure of opioid.
- Trial name
- NCT01732666
- Testing
- Nefopam, low dose remifentanil, high dose remifentanil
- Where
- South Korea
- Volunteers
- 25 people
- Sponsor
- Yonsei University
Anesthesia, Electroconvulsive Therapy
Comparison of Propofol, Propofol-remifentanil and Propofol-ketamine Anesthesia During Electroconvulsive Therapy
Electroconvulsive therapy (ECT) is a common treatment method used in severe depression and other psychiatric diseases. Currently, most ECT procedures are carried out with muscle paralysis under general anaesthesia.
- Trial name
- NCT02819375
- Testing
- Propofol, Propofol+Remifentanil, Propofol+Ketamine
- Volunteers
- 45 people
- Sponsor
- Inonu University