Clinical trials: Resistance training
Stroke
Effects of Oropharyngeal Strengthening on Dysphagia in Patients Post-stroke
The overall goal of this randomized controlled pilot study is to characterize effects of SwallowSTRONG® Device-Facilitated Isometric Progressive Resistance Oropharyngeal (DF I-PRO) therapy in a dose response framework on…
- Trial name
- StrokeStrong (NCT02322411)
- Testing
- Isometric Progressive Resistance Oropharyngeal Therapy, Compensatory approaches
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Wisconsin, Madison
Lung Neoplasms
The Impacts of Pulmonary Rehabilitation Therapy on Patients After Thoracic Surgery
The advantages of thoracoscopic surgery include smaller wounds, fewer postoperative complications, and shortened hospital stay. However,complications such as pain, pulmonary function insufficiency, pneumonia,postoperative…
- Trial name
- VATSMIPMEP (NCT02757092)
- Testing
- Home-based Pulmonary Rehabilitation
- Where
- 2 sites in Taiwan
- Volunteers
- 36 people
- Sponsor
- Chang Gung Memorial Hospital
Aging
Fatigability of Lower Limb Muscle in Older Adults: Protective Effects of Strength Training Exercise in Old Men and Women
The proposed studies will assess 1) the mechanisms for the age-related increase in fatigability during dynamic exercise (Aims 1 and 2) and 2) the effectiveness of high-velocity resistance training coupled with blood flow…
- Trial name
- NCT03888040
- Testing
- Exercise
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Marquette University
COPD
COPD Access to Pulmonary Rehabilitation Intervention
Persons with COPD have significant functional disability but cannot access rehabilitative treatment at hospital-based conventional pulmonary rehabilitation (PR) programs.
- Trial name
- CAPRI (NCT03794921)
- Testing
- Every Step Counts
- Where
- United States
- Volunteers
- 146 people
- Sponsor
- VA Office of Research and Development
HIV Infections, Type 2 Diabetes
Exercise and Pioglitazone for HIV-Metabolic Syndromes
The purpose is to examine the safety and efficacy of 16wks of pioglitazone (Actos; 30mg/d) with and without aerobic and strength exercise training for reducing glucose intolerance and central adiposity in HIV-infected people.
- Conditions
- HIV Infections, Type 2 Diabetes, Obesity, HIV
- Trial name
- NCT00639457
- Testing
- Pioglitazone, Exercise training
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Pulmonary Disease, Chronic Obstructive
The Impact of a Home-based Pulmonary Telerehabilitation Program in Acute Exacerbations of COPD
COPD impacts a significant proportion of the Veteran population. Acute exacerbations, or flare-ups, of COPD are associated with impaired muscle function and worse quality of life.
- Trial name
- NCT03997513
- Testing
- Pulmonary Telerehabilitation
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- VA Office of Research and Development
Dementia, Alzheimer Disease
A Multidomain Intervention Program for Older People With Dementia
This is a pilot study to assess the feasibility of a multidomain intervention for older people with dementia in nursing homes. Participants will be randomized into two equal groups, to receive either an intensive multidomain…
- Conditions
- Dementia, Alzheimer Disease, Dementia, Mixed
- Trial name
- NCT04948450
- Testing
- Physical activity intervention, Cognitive stimulation intervention, Social intervention
- Where
- 4 sites in Vietnam
- Volunteers
- 60 people
- Sponsor
- National Geriatric Hospital
Attention Deficit Hyperactivity Disorder
Treatment of Children With ADHD Who do Not Fully Respond to Stimulants
The purpose of this pilot is to initiate a program of research into the development of effective medication techniques to treat those children with ADHD who are referred because they are "partial" or "non-responders" to standard…
- Trial name
- TREAT (NCT00279409)
- Testing
- aripiprazole, Sugar pill
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- New York State Psychiatric Institute
Frailty Syndrome
Ghrelin Plus Strength Training in Frail Elderly Study
Frailty is a geriatric syndrome leading to physical deterioration including muscle wasting (sarcopenia) and unintentional weight loss. There are currently no approved therapies for frailty.
- Trial name
- NCT01898611
- Testing
- Ghrelin
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of Pennsylvania
Postural Balance, Accidental Falls
Improving Balance and Mobility
Falls are dangerous leading to injuries and even death. The VA has made fall prevention a priority, but effective programs only reduce falls by 30%.
- Conditions
- Postural Balance, Accidental Falls, Mobility Limitation
- Trial name
- MMBI (NCT02374463)
- Testing
- MMBI, Tai Chi
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Cardiovascular Diseases
Impact of Statin Therapy on Adaptations to Aerobic Exercise
The purpose of this study is to determine how different doses of a statin affect muscle health and exercise.
- Trial name
- NCT03360916
- Testing
- Lipitor 20Mg Tablet, Lipitor 80Mg Tablet, Exercise Program
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Multiple Sclerosis, Fatigue
Telephone-Delivered Exercise for Multiple Sclerosis Fatigue
Multiple sclerosis (MS) is a progressive demyelinating disorder that damages white matter in the central nervous system. Although individuals experience mobility (e.g., walking, balance) impairments that lower quality of life and…
- Conditions
- Multiple Sclerosis, Fatigue, Physical Activity
- Trial name
- NCT03256851
- Testing
- Telephone-Delivered Exercise Therapy, In-Person Delivered Exercise Therapy
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Wayne State University
Fecal Incontinence
Controlling Anal Incontinence by Performing Anal Exercises With Biofeedback or Loperamide (CAPABLe)
The study is a multi-center, randomized, placebo controlled trial with participants randomized into one of four groups: 1. placebo/usual care (educational pamphlet) 2. loperamide/usual care (educational pamphlet) 3.
- Trial name
- CAPABLe (NCT02008565)
- Testing
- Loperamide, Anal exercises with biofeedback, Usual Care
- Where
- 9 sites in United States
- Volunteers
- 300 people
- Sponsor
- NICHD Pelvic Floor Disorders Network
Sarcopenia
Time Course Adaptations Using Deuterated Creatine (D3Cr) Method
The pilot study is to assess the feasibility of using a new method to measure muscle mass called Deuterated Creatine (D3Cr) method and thereby understand the role of muscle mass on functional outcomes in older adults.
- Trial name
- NCT03573583
- Testing
- Resistance Training, Successful Aging
- Where
- 2 sites in United States
- Volunteers
- 21 people
- Sponsor
- University of Florida
Pediatric Obesity
Pediatric Quality of Life Among Population With Body Mass Index (BMI) Greater Than or Equal to 85%
We are currently experiencing an epidemic of obesity in the Pediatric Population. This epidemic affects many areas including quality of life. We have been conducting a nutrition and exercise program since 2003.
- Trial name
- NCT00714870
- Testing
- Behavioral nutrition and exercise program
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Steward St. Elizabeth's Medical Center of Boston, Inc.
Spinal Cord Injuries, Tetraplegia
Study Testing Benefits of Ursolic Acid (UA) as a Countermeasure To Myopenia and Insulin Resistance in Chronic Spinal Cord Injury (SCI)
This study will evaluate if Ursolic Acid supplementation may be effective in reducing muscle loss and improving blood sugar control in the SCI community.
- Conditions
- Spinal Cord Injuries, Tetraplegia, Paraplegia, Muscle Loss
- Trial name
- NCT05776862
- Testing
- Ursolic Acid, Strength Training
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Miami
Healthy
Validation of a Digital Twin Performing Strength Training
Background: Muscular strength training interventions have long been a cornerstone in the prevention, non-surgical management and rehabilitation of the entire spectrum of musculoskeletal injuries and diseases.
- Trial name
- NCT04849923
- Testing
- Strength training session
- Where
- Switzerland
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Silvio Lorenzetti
Knee Osteoarthritis, Symptomatic Knee Osteoarthritis
Assessment of Efficacy of Low Intensity Resistance Training in Women at Risk for Symptomatic Knee Osteoarthritis
The purpose of this study is to asses the efficacy of a 4 week low-intensity resistance training program with concurrent application of partial blood flow restriction (PBFR) to the exercising limbs to improve quadriceps strength…
- Trial name
- PBFR2 (NCT01440972)
- Testing
- partial blood flow restriction (PBFR), low intensity resistance training
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Breast Cancer, Coronary Artery Disease
Reducing Metabolic Dysregulation in Obese Latina Breast Cancer Survivors Using Physical Activity
This study is about testing whether exercise will improve fitness and lessen risk factors related to heart disease, diabetes, and obesity in Latina breast cancer survivors.
- Conditions
- Breast Cancer, Coronary Artery Disease, Stroke, Type2 Diabetes
- Trial name
- NCT04717050
- Testing
- Progressive combine training (PCT), Attention Control (AC)
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Dana-Farber Cancer Institute
Pompe Disease
Safety Study of Recombinant Adeno-Associated Virus Acid Alpha-Glucosidase to Treat Pompe Disease
Pompe disease is an inherited condition of acid alpha-glucosidase (GAA) deficiency resulting in lysosomal accumulation of glycogen in all tissues. Glycogen accumulation leads to muscle dysfunction and profound muscle weakness.
- Trial name
- NCT00976352
- Testing
- rAAV1-CMV-GAA (study agent) Administration, RMST
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of Florida