Clinical trials: Ropivacaine
Drug Safety, Self Efficacy
Efficacy and Safety Study of Dexmedetomidine as an Additive to Local Anesthetics in Shoulder Surgery
The purpose of this study is to test the efficacy and safety of dexmedetomidine added to ropivacaine in patients undergoing shoulder surgery.
- Trial name
- NCT01557270
- Testing
- dexmedetomidine, saline
- Where
- Austria
- Volunteers
- 62 people
- Sponsor
- Prof. Peter Gerner, M.D.
Kidney Cancer, Post-surgical Pain
ESP Block for Laparoscopic Nephrectomy Surgeries
Nephrectomy (kidney removal) is one of the most common surgical procedures in urologic practice. Recent advances in laparoscopic (keyhole) procedures have resulted in a significant decrease in open nephrectomies.
- Trial name
- ESPB (NCT04085237)
- Testing
- Ropivacaine injection
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- McMaster University
Post-operative Pain, Gallstone Disease
Effects of Calot's Triangle Block for Postoperative Analgesia in Patients Undergoing Laparoscopic Cholecystectomy: a Prospective, Randomized, Double-blind, Controlled, Clinical Trial
Chronic pain after laparoscopic cholecystectomy (LC) is a common complication with an incidence ranging between 3-56%. In many cases, however, the cause chronic pain after LC remains unknown and visceral hyperalgesia and central…
- Trial name
- NCT02300480
- Testing
- CTB group, PCIA group
- Where
- China
- Volunteers
- 140 people
- Sponsor
- First Affiliated Hospital of Chongqing Medical University
Pain After Total Knee Arthroplasty
Effect of Adductor-Canal-Blockade on High Pain Responders After Total Knee Arthroplasty
The purpose of this study is to determine whether Adductor-Canal-Blockade (ACB) is superior to placebo when it comes to analgetic efficacy in high pain responders after Total Knee Arthroplasty (TKA).
- Trial name
- NCT01549704
- Testing
- Ropivacaine, Saline
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- University Hospital, Gentofte, Copenhagen
Malignant Neoplasm of Breast
MIRs 04 : Interpectoral Nerve Block With Ropivacaine Versus Placebo Before Breast Cancer Surgery
Compare the effect of ropivacaine versus placebo pectoral nerve block (Pecs 1 and 2) on acute pain after tumorectomy plus sentinel lymph node dissection on one day surgery.
- Trial name
- MIRs 04 (NCT04327063)
- Testing
- Saline, Ropivacaine
- Where
- 4 sites in France
- Volunteers
- 182 people
- Sponsor
- Institut Curie
Osteoarthritis, Knee
A Study to Compare the Effectiveness of Adductor Canal Pain Catheters Following Total Knee Arthroplasty
The purpose of this research is to study how well the adductor canal pain catheters works after a total knee arthroplasty or replacement of the knee joint.
- Trial name
- NCT05053087
- Testing
- Ropivacaine Continuous Infusion, Ropivacaine Intermittent Bolus
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Mayo Clinic
Adhesive Capsulitis, Frozen Shoulder
The Effect of 3 Ropivacaine Suprascapular Nerve Blocks in Subacute Adhesive Capsulitis: a Randomized Controlled Trial
Patients presenting with subacute, less than 6 months of evolution, adhesive capsulitis are randomly attributed to the control or study group.
- Conditions
- Adhesive Capsulitis, Frozen Shoulder, Nerve Block
- Trial name
- NCT02944526
- Testing
- Ropivacaine Monohydrochloride
- Where
- Belgium
- Volunteers
- 36 people
- Sponsor
- Clinique Saint-Jean, Bruxelles
Regional Anesthesia, Diaphragm Issues
Ultrasound Assessment of Diaphragmatic Dysfunction in Regional Anesthesia
Awake thoracic surgery is a feasible and safe alternative to general anesthesia for pulmonary biopsy in interstitial lung disease patients, but there is still no evidence as to its superiority in terms of outcome.
- Conditions
- Regional Anesthesia, Diaphragm Issues, Thoracic Surgery, Ultrasounds
- Trial name
- NCT04700943
- Testing
- Regional awake anesthesia
- Where
- Italy
- Volunteers
- 41 people
- Sponsor
- University of Turin, Italy
Bariatric Surgery, Transverse Abdominal Plane Regional Blocks
Regional TAP Block for Bariatric Patients
Addition of transverse abdominis plane (TAP) block to general anesthesia for morbidly obese patients (BMI >35) undergoing laparoscopic bariatric surgery for weight loss will significantly reduce opioid use in the recovery room
- Trial name
- NCT04051684
- Testing
- Transverse abdominal plane block, Ropivacaine
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Montefiore Medical Center
Analgesia
IPACK or Selective Tibial Nerve Block for ACL Reconstruction With an Adductor Canal Block
The purpose of this study is to compare the analgesic efficacy of the combination of an adductor canal and selective tibial nerve blocks versus adductor canal block and IPACK after ACL reconstruction under general anaesthesia.
- Trial name
- TIPACK (NCT05303233)
- Testing
- Selective tibial nerve block, IPACK
- Where
- Switzerland
- Volunteers
- 80 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Pain
Analgesic Effect of Ropivacaine Plus Fentanyl vs Ropivacaine for Continuous 3-in-1 FNB After Total Knee Arthroplasty
The postoperative analgesic effect of the continuous 3-in-1 femoral nerve block (FNB) with ropivacaine/fentanyl or with ropivacaine were compared in total knee arthroplasty.
- Trial name
- NCT02501863
- Testing
- Femoral nerve block with ropivacaine+fentanyl, Femoral nerve block with ropivacaine
- Volunteers
- 40 people
- Sponsor
- National Medical Center, Seoul
Arthroplasty, Replacement
Comparison of Comparison of Ropivacaine and Liposomal Bupivacaine for Total Knee Arthroplasty
This is a randomized prospective outcomes study comparing two groups of patients. One group will receive liposomal bupivacaine for a periarticular injection.
- Conditions
- Arthroplasty, Replacement, Knee
- Trial name
- NCT02616367
- Testing
- liposomal bupivacaine Periarticular injection, Ropivacaine Periarticular Injection
- Sponsor
- University of Minnesota
Shoulder Arthroscopy, Ultrasound-guided Interscalene Nerve Block
Optimal Location of Local Anesthetic Injection for Ultrasound Guided Interscalene Block
This is a prospective randomized clinical trial to determine where is the optimal location for local anesthetic injection for ultrasound guided interscalene nerve blocks.
- Trial name
- NCT01877330
- Testing
- Interscalene block for shoulder arthroscopy
- Where
- United States
- Volunteers
- 208 people
- Sponsor
- University of California, San Francisco
Cluneal Syndrome, Nerve Entrapment Syndrome
Study on the Efficacy of Infiltration of Upper Cluneal Nerves in Chronic Pain Related to Cluneal Syndrome
Lower back pain is a very common complaint in the Chronic Pain Clinic. Its etiology is nonspecific in 85% of the cases. In 1957, Strong and Davila reported that the superior cluneal nerves (SCNs) and middle cluneal nerves (MCNs)…
- Trial name
- NCT05423132
- Testing
- Ropivacaine injection, Physiological serum injection
- Sponsor
- Centre Hospitalier Universitaire Saint Pierre
Primary Total Knee Arthroplasty
Quadriblock Versus "IPACK + Femoral Triangle Block + Obturator Nerve Block" in Total Knee Arthroplasty
Total knee arthroplasty (TKA) is one of the most common orthopedic surgical procedure and is associated with severe pain in the immediate postoperative period, thus limiting early recovery.
- Trial name
- QuITO (NCT04499716)
- Testing
- IPACK, Femoral triangle block, Obturator nerve block
- Where
- France
- Volunteers
- 90 people
- Sponsor
- Clinique Medipole Garonne
Glenohumeral Arthritis, Total Shoulder Arthroplasty
Pain Management After Total Shoulder Arthroplasty
The purpose of the study is to determine if pain management after total shoulder arthroplasty is more efficacious with ultrasound guided, continuous Interscalene block or with local tissue infiltration with liposomal bupivacaine.
- Trial name
- NCT03219983
- Testing
- Ropivacaine, liposomal bupivacaine
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- The Christ Hospital
Cytoreductive Surgery, Hyperthermic Intra-peritoneal Chemotherapy
Quadratus Lumborum Block After Cytoreductive Surgery and Hyperthermic Intra-peritoneal Chemotherapy
This study aims to assess whether transmusculr quadratus lomborum block (QL block) can reduce postoperative pain after cytoreductive surgery and hyperthermic intra-peritoneal chemotherapy (CRS and HIPEC).
- Conditions
- Cytoreductive Surgery, Hyperthermic Intra-peritoneal Chemotherapy, Peritoneal Cancer
- Trial name
- NCT05597683
- Testing
- Arm I (QL block and multimodal analgesia), Arm II (multimodal analgesia without regional block)
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Gangnam Severance Hospital
Pain Management, Arthroplasty Total Hip Replacement
QLESP Block Versus PENG+LFCN Block for Total Hip Arthroplasty
Total hip arthroplasty (THA) is a common surgery to replace damaged hip joints, but many patients experience significant pain after surgery, which can delay recovery and increase the need for strong pain medications (opioids).
- Trial name
- QLESP (NCT07771829)
- Testing
- QLESP Block, PENG+LFCN Block, ropivacaine
- Where
- China
- Volunteers
- 136 people
- Sponsor
- Huazhong University of Science and Technology
Depression, Postpartum, Analgesia, Obstetrical
CODEPAD (Collaborative Outcomes of DEpression and Pain Associated With Delivery)
Postnatal depression affects about 10-15% of women after childbirth. Approximately 3-5% of women experience a moderate-to-severe depression that requires medical attention.
- Conditions
- Depression, Postpartum, Analgesia, Obstetrical, Anesthesia, Obstetrical
- Trial name
- CODEPAD (NCT03167905)
- Testing
- Epidural delivery system, Entonox, Meperidine
- Where
- Singapore
- Volunteers
- 881 people
- Sponsor
- KK Women's and Children's Hospital
Facial Palsy, Neuropathy
Stellate Gnaglion Block in Refractory Bell's Palsy
Idiopathic facial nerve palsy (Bell's palsy) is caused by damage to the facial nerve at any site of the peripheral branches after the facial nucleus.Stellate ganglion block is inteneded to increase blood flow and promotes nerve…
- Trial name
- NCT05094245
- Testing
- Stellate Ganglion Block Group
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
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