Clinical trials: Ropivacaine
Osteoarthritis, Knee, Osteoarthritis, Hip
Liposomal Bupivacaine Versus Standard Analgesia in Total Joint Arthroplasty (TJA)
The purpose of this study is to determine whether liposomal bupivacaine is effective in the management of pain following total joint arthroplasty, as compared to standard of care analgesia.
- Conditions
- Osteoarthritis, Knee, Osteoarthritis, Hip, Osteoarthritis, Shoulder
- Trial name
- NCT02197273
- Testing
- Liposomal bupivacaine, Standard of care analgesia
- Where
- United States
- Volunteers
- 211 people
- Sponsor
- OhioHealth
Osteo Arthritis Knee
High Versus Low Adductor Canal Block
The investigators will be comparing the efficacy of two different techniques for performing an adductor canal block to the saphenous nerve as a part of the multimodal pain control regimen for total knee arthroplasty.
- Trial name
- NCT04155983
- Testing
- Ropivacaine
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Carilion Clinic
Hepatectomy
EOI Block vs. TAP Block in Minimally Invasive Hepatectomy
This study aims to compare the analgesic efficacy of two different ultrasound-guided nerve blocks-the External Oblique Intercostal (EOI) block and the Subcostal Transversus Abdominis Plane (TAP) block-in patients undergoing…
- Trial name
- EOIvsTAP (NCT07615231)
- Testing
- External Oblique Intercostal Block, TAP Block
- Where
- South Korea
- Volunteers
- 140 people
- Sponsor
- Seoul National University Hospital
Arthroplasty, Knee Replacement
Neurostimulation an Adjuvant Postoperative Analgesic in Total Knee Replacement (TKR) Surgeries
To study and evaluate the effect of using the Primary Relief PENS treatment as adjuvant analgesia for reducing pain in total knee replacement (TKR) patients.
- Trial name
- TKR (NCT05416294)
- Testing
- Primary Relief, Inactive Primary Relief
- Sponsor
- DyAnsys, Inc.
Laparoscopic Abdominal Surgery
Study on the Effects of Multimodal Analgesia Regimens on Postoperative Analgesia and Gastrointestinal Function Recovery After Laparoscopic Abdominal Surgery
This clinical trial aims to investigate the impact of multimodal analgesia regimens on postoperative pain management and gastrointestinal function recovery following laparoscopic abdominal surgery.
- Trial name
- NCT06772545
- Testing
- Epidural Analgesia, Paravertebral Block, Transversus Abdominis Plane Block
- Volunteers
- 120 people
- Sponsor
- Xiaguang Duan
Postoperative Pain, Laparoscopic Cholecystectomy
EOIB for Pain After Laparoscopic Cholecystectomy
This prospective, randomized, controlled, assessor-blinded trial will evaluate whether bilateral ultrasound-guided external oblique intercostal block (EOIB) reduces postoperative opioid consumption and improves recovery after…
- Trial name
- NCT07332546
- Testing
- External oblique intercostal block (EOIB), Standard care without regional block
- Where
- China
- Volunteers
- 56 people
- Sponsor
- Shiyou Wei
Knee Osteoarthritis, Knee Pain Chronic
iPACK Block for Total Knee Arthroplasty
This randomized, double-blinded, placebo-controlled trial seeks to evaluate the efficacy of the rehabilitation process of the Interspace between the Popliteal Artery and Capsule of the Posterior Knee (iPACK) block in total knee…
- Conditions
- Knee Osteoarthritis, Knee Pain Chronic, Knee Disease
- Trial name
- NCT06087562
- Testing
- Ropivacaine 0.5% Injectable Solution 20mL, 0,9% normal saline 20mL
- Where
- Poland
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Poznan University of Medical Sciences
Stellate Ganglion Block, Heart Valve Replacement (Mechanical or Biological With AF)
Effect of Ultrasound-guided Left Stellate Ganglion Block on Rapid Recovery of Patients Undergoing Cardiac Valve Replacement and Its Mechanism
In this study, Valve replacement patients undergoing cardiopulmonary bypass were randomly divided into control group and experimental group (SGB Group) , main outcome measures: postoperative complications (pulmonary infection…
- Trial name
- NCT05587023
- Testing
- stellate ganglion block
- Where
- China
- Volunteers
- 62 people
- Sponsor
- Zhonghua Chen,MD
Postoperative Pain
Outcomes for Anesthesiologist-Led Care of Analgesic Protocol in Anorectal Surgery
This will be an open, prospective, parallel-group, randomized controlled trial. Patients scheduled for complex anorectal surgery under general anesthesia will be enrolled, and the perioperative analgesia mode led by…
- Trial name
- NCT06015165
- Testing
- Analgesia plan for Anes. Group, Analgesia plan for Surg. Group, Multi-modal analgesia during the surgery
- Where
- 2 sites in China
- Volunteers
- 216 people
- Sponsor
- China-Japan Friendship Hospital
Postoperative Pain
Total Knee Arthroplasty Infiltration Study for Postoperative Analgesia
This is a Phase 2b, randomized, double-blind, saline placebo- and active-controlled, multicenter study in subjects undergoing primary unilateral total knee arthroplasty (TKA) to evaluate the analgesic efficacy, safety, and…
- Trial name
- NCT03015532
- Testing
- HTX-011, Bupivicaine HCl, Ropivacaine
- Where
- 24 sites in United States
- Volunteers
- 285 people
- Sponsor
- Heron Therapeutics
Hip Fractures, Ultrasound-guided Nerve Block
Fascia Iliaca Compartment Block and Tramadol for Analgesia in Hip Fracture
Hip fractures are a growing public health concern globally due to the aging population, with high incidence and significant mortality rates one year post-fracture.
- Conditions
- Hip Fractures, Ultrasound-guided Nerve Block, Perioperative Analgesia
- Trial name
- NCT06728033
- Testing
- supra-inguinal fascia iliaca compartment block, Tramadol
- Where
- China
- Volunteers
- 240 people
- Sponsor
- West China Hospital
Breast Cancer
Transversus Thoracic Muscle Plane Combined With Pectoral Nerves Block for Breast Cancer Surgery
This is a prospective, randomized, controlled trial for evaluating the efficacy of addition of transversus thoracic muscle plane block to pectoral nerves block versus pectoral nerves block for quality of recovery scores in breast…
- Trial name
- NCT05448638
- Testing
- the combination of transversus thoracic muscle plane and pectoral nerves blocks, the pectoral nerves block only
- Where
- China
- Volunteers
- 116 people
- Sponsor
- Zhejiang Cancer Hospital
Syndesmotic Injuries
Bilateral External Torque CT, a Novel Diagnostic Tool for Detection of Syndesmotic Insufficiency
Study population: the investigator set them sample size to 30 patients. Primary endpoint (concerning both study questions): is the applied torque measurement in Newton meters (maximum up to 7.5 Nm) up to the pain tolerance limit.
- Trial name
- NCT05625516
- Testing
- Bilateral external torque device
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- Balgrist University Hospital
Knee Arthroplasty
Perioperative Analgesia After Knee Arthroplasty
The purpose of this study is to compare two accepted methods of pain control in knee arthroplasty surgery.The first method combines the periarticular injection of ropivacaine with continuous blockade of the femoral nerve.The…
- Trial name
- NCT01225484
- Testing
- Continuous femoral nerve block + periarticular infiltration, Intraarticular and periarticular ropivacaine
- Where
- Austria
- Volunteers
- 123 people
- Sponsor
- Landeskrankenhaus Feldbach
Pregnancy, Atelectasis
Evaluation of Regional Distribution of Ventilation During Labor With or Without Epidural Analgesia
With an efficient epidural analgesia the physiological effects of pain are disabled during labor. Pain may cause an increase of minute volume, oxygen consumption and a decrease of paCO2 (Arterial CO2 pressure).
- Trial name
- NCT02523755
- Testing
- Epidural analgesia Ropivacaine, Absence of epidural analgesia
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- Universitair Ziekenhuis Brussel
Muscle Strength, Healthy Volunteers
Adductor-Canal-Blockade Versus the Femoral Nerve Block Effect on Muscle Strength and Mobilization in Healthy Volunteers
The aim of this study is to investigate the efficacy of the Adductor-Canal-Blockade versus the femoral nerve block versus placebo on muscle strength in healthy volunteers.
- Trial name
- NCT01449097
- Testing
- Adductor-Canal-Blockade, The femoral nerve block
- Where
- Denmark
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Postoperative Pain
Ropivacaine Use in Femoral Nerve Block; What is the Minimal Effective Analgesic Concentration (MEAC 90)
The aim of this study is to determine the minimal effective ropivacaine concentration required to provide adequate analgesic femoral nerve block in 90% of patients (MEAC90)
- Trial name
- NCT04834440
- Testing
- Ropivacaine
- Where
- United Arab Emirates
- Volunteers
- 45 people
- Sponsor
- Healthpoint Hospital
Arthropathy of Knee Joint
Evaluation of Optimal Dose of Local Anesthetics for Patient Controlled Continuous Femoral Nerve Block
To evaluate an analgesic effect without basal administration of local anesthetics for patient-controlled femoral nerve block (with sciatic nerve block) after total knee arthroplasty.
- Trial name
- NCT01198340
- Testing
- PC-FNB with basal administration of local anesthetics, PC-FNB without basal local anesthetics
- Where
- Japan
- Volunteers
- 60 people
- Sponsor
- Okayama University
Postoperative Pain, Knee Arthroplasty
Postoperative Pain Management After Total Knee Arthroplasty
The study compares three different analgesic techniques in order to determine which one serves as the optimal method for postoperative pain management after Total Knee Arthroplasty in patients suffering from Osteoarthritis
- Trial name
- NCT04344990
- Testing
- Epidural analgesia - Group E, Femoral blockade - Group F, Intraarticular infusion - Group I
- Where
- Greece
- Volunteers
- 72 people
- Sponsor
- University Hospital of Patras
Healthy
Does Perineural Clonidine Prolong Duration of a Nerve Block?
The aim of this trial is to investigate if clonidine prolongs the duration of an adductor canal block. By using healthy volunteers the investigators can perform a bilateral adductor canal block and thereby control for a systemic…
- Trial name
- NCT02444559
- Testing
- Ropivacaine 20ml 5mg/ml+ Clonidine 150ug
- Where
- Denmark
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Zealand University Hospital
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