Clinical trials: Ropivacaine
Knee Pain Chronic
Chronic Pain and Functional Prognosis After Total Knee Replacement: Continuous Locoregional Analgesia by Catheter to the Femoral Triangle Versus Tissue Infiltration as Part of an Improved Rehabilitation After Surgery Approach
The prevalence of Chronic Post-Surgical Pain (CPSP) after knee replacement, defined as pain greater than or equal to 4/10 on the visual analogue scale after the third postoperative month, is recognised as high, with an average of…
- Trial name
- TKAFTER (NCT03998813)
- Testing
- Ropivacaine
- Where
- 5 sites in France
- Volunteers
- 287 people
- Sponsor
- Centre Hospitalier Departemental Vendee
Inguinal Hernia
The Addition of Hydromorphone to Local Anesthetics for the Repair of Inguinal Hernias in Elderly Patients
To compare the clinical and postoperative analgesic effects of hydromorphone combined with ropivacaine and ropivacaine alone in quadrangular muscle block for open inguinal hernia in elderly patients.
- Trial name
- NCT06218160
- Testing
- Hydromorphone combined with ropivacaine, Ropivacaine
- Where
- China
- Volunteers
- 63 people
- Sponsor
- Second Hospital of Jilin University
Postoperative Pain, Total Knee Arthroplasty
Continuous Femoral Nerve Block Versus Local-wound Infiltration Analgesia For Patients Receiving Total Knee Arthroplasty --- A Randomized Controlled Trial
Post-operative pain after total knee arthroplasty is usually severe and impair the functional recovery of operated joints.The purpose of this study is to determine whether post-operative continuous femoral nerve block analgesia…
- Trial name
- NCT02284620
- Testing
- CFNB group, LWI group
- Where
- China
- Volunteers
- 320 people
- Sponsor
- First Affiliated Hospital of Chongqing Medical University
Knee Osteoarthritis, Musculoskeletal Disease
Use of Corticosteroid in Intraopertive Injections in Total Knee Replacement Surgery.
The goal of this clinical trial is to find out which type of steroid medicine, when added to a standard pain-control injection during total knee replacement surgery, works best at reducing pain, limiting opioid use, and improving…
- Conditions
- Knee Osteoarthritis, Musculoskeletal Disease, Surgery
- Trial name
- TKACSI (NCT07151417)
- Testing
- PAI, PAI + steroid, PAI + zilretta
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Walter Reed National Military Medical Center
Cryptorchidism
Comparison of Dexamethasone Added to Ropivacaine and Ropivacaine Alone in Caudal Analgesia in Children Undergoing Orchiopexy
Single shot caudal epidural block is one of the most widespread technique for pediatric pain management after infraumbilical surgical procedures.
- Trial name
- NCT01604915
- Testing
- Caudal block
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Yonsei University
Low Back Pain
Clinical Evaluation of the ReLeaf Analgesic Infusion Catheter & Wound Drain
The purpose of this study is to evaluate the clinical performance of the ReLeaf infusion catheter \& wound drain in patients following lumbar spinal fusion surgery.
- Trial name
- NCT02293525
- Testing
- ReLeaf catheter, Ropivacaine, Saline
- Sponsor
- Vital 5, LLC
Bariatric Surgery Candidate
The Use of Laparoscopic Transversus Abdominis Plane Block in Gastric Bypass Surgery (LapTAP)
Randomized, Double-Blinded, Placebo-Controlled Trial of Laparoscopic Transverse Abdominis Plane (Lap TAP) and Rectus Sheath Block in elective Gastric Bypass Surgery aiming to evaluate the benefit of a laparoscopically -guided…
- Trial name
- LapTAP (NCT03367728)
- Testing
- Ropivacaine, Normal saline
- Where
- Canada
- Volunteers
- 148 people
- Sponsor
- Ottawa Hospital Research Institute
Internal Derangement of Hip, Acetabular Labrum Tear
Preemptive Femoral & Lateral Femoral Cutaneous Nerve Blocks for THA Acute Pain
The goal of the study is to evaluate via a prospective, blinded, randomized clinical trial, whether ultrasound-guided single femoral and lateral femoral cutaneous nerve blocks with ropivacaine 0.5% with epinephrine (1:200,000) as…
- Trial name
- NCT01997567
- Testing
- Ropivacaine
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Rush University Medical Center
Bowel Disease, Liver Diseases
The Impact of an Epidural Anesthetic on the Consumption of Sevoflurane in Major Abdominal Surgery
Major abdominal surgery - like non-laparoscopic bowel resection, liver, gastric, or pancreas surgery - is performed under general anesthesia.
- Conditions
- Bowel Disease, Liver Diseases, Pancreas Disease, Anesthesia; Functional
- Trial name
- NCT04021264
- Testing
- Ropivacaine-Sufentanil, Dextrose 5
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Alberta
Osteoarthritis
A Trial Between the Intra-articular Local Anesthetic Infiltration With Catheter and Interscalene Block With Catheter in Postoperative Analgesia After Shoulder Prosthesis
The control of perioperative pain is necessary to avoid worst surgical suites after shoulder arthroplasty. Interscalene block (ISB) with or without catheter is the gold standard in postoperative analgesia after shoulder…
- Trial name
- LIA (NCT02365181)
- Testing
- intra-articular local anesthetic infiltration, inter-scalene block, Ropivacaine 2 %
- Where
- 5 sites in France
- Volunteers
- 98 people
- Sponsor
- Hospital Ambroise Paré Paris
Cadiac Surgery, Median Sternotomy
Analgesic Effect of Bilateral Erector Spinae Plane Block With Ropivacaine After Sternotomy for Cardiac Surgery
The sternotomy site is the most painful area after cardiac surgery. Erector spinae plane block is effective in thoracic and abdominal surgery, but literature is lacking in cardiac surgery.
- Conditions
- Cadiac Surgery, Median Sternotomy, Regional Anesthesia, Postoperative Pain
- Trial name
- ESB-Sterno (NCT05160298)
- Testing
- Ropivacaine 0,2% Injectable Solution, Control group
- Where
- France
- Volunteers
- 84 people
- Sponsor
- University Hospital, Clermont-Ferrand
Complex Regional Pain Syndrome I of Upper Limb
RCT :Thoracic Sympathetic Block for the Treatment of Complex Regional Pain Syndrome I of the Upper Limb
This is a double-blind randomized controlled trial to evaluate the efficacy of the sympathetic block via thoracic vertebra T3 for the treatment of CRPS I upper limb.
- Trial name
- NCT01612364
- Testing
- thoracic sympathetic block
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- University of Sao Paulo
Abdominal Tumor, Postoperative Analgesia
Liposomal Bupivacaine vs Ropivacaine for TAPBs
Few studies have compared the efficacy of ultrasound (US)-guided TAP blocks with Liposomal bupivacaine(LB) versus ropivacaine in reducing postoperative opioid usage in patients undergoing laparoscopic lower abdominal tumor…
- Conditions
- Abdominal Tumor, Postoperative Analgesia, Liposomal Bupivacaine, Ropivacaine
- Trial name
- NCT06430112
- Testing
- Liposomal Bupivacaine, Ropivacaine
- Where
- China
- Volunteers
- 74 people
- Sponsor
- Sun Yat-sen University
Brachial Plexus Injury
Incidence of Brachial Plexus Injury After Rotator Cuff Repair With Continuous Interscalene Block
Brachial plexus injury after shoulder surgery with continuous interscalene block is 2.4% at 1 month and 0% at 6 months, but may be higher with a systematic postoperative neurological examination.
- Trial name
- NCT01334632
- Testing
- Continuous interscalene block, PCA morphine
- Where
- Switzerland
- Volunteers
- healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Postoperative Pain
Preoperative Versus Postoperative Ultrasound-guided Rectus Sheath Block for Sleep Quality and Cytokines of Patients
Rectus sheath block (RSB) is used for postoperative pain relief in patients undergoing abdominal surgery with a midline incision.
- Trial name
- NCT02477098
- Testing
- preoperative 0.5% ropivacaine hydrochloride preoperative, postoperative 0.5% Ropivacaine hydrochloride
- Where
- China
- Volunteers
- 77 people
- Sponsor
- China Medical University, China
Regional Anesthesia, Heart Surgery
Nociception-directed Erector Muscle Spinae Plane Block in Open Heart Surgery
With the advent of ultrasound (US) guidance, use of regional anaesthesia (RA) is poised to grow and evolve. Recently, cardiac surgery has benefited from newer US guided interfascial techniques as they promise to fulfil all the…
- Trial name
- NESP (NCT04338984)
- Testing
- General anesthetic, Ropivacaine 0.5% Injectable Solution
- Where
- Romania
- Volunteers
- 86 people
- Sponsor
- Institutul de Urgenţă pentru Boli Cardiovasculare Prof.Dr. C.C. Iliescu
Pain, Postoperative, Hip Dysplasia
Ultrasound Guided Psoas Compartment Block vs Suprainguinal Fascia Iliaca Compartment Block
The aim of this study was to compare the intraoperative and the postoperative analgesic effect of psoas compartment block (PCB) and supra-inguinal fascia iliaca compartment block (SFIB) in pediatric patients undergoing…
- Trial name
- NCT05543109
- Testing
- Fentanyl, Propofol, Rocuronium
- Where
- Egypt
- Volunteers
- 85 people
- Sponsor
- Tanta University
Intercostal Nerve Block, Pulmonary Ventilation
EIT Evaluation of Pulmonary Ventilation With Different Ropivacaine Concentrations in Intercostal Nerve Blockade
This study aims to find out how different strengths of the anesthetic drug ropivacaine affect lung breathing function when used in intercostal nerve block (a type of local anesthesia) for breast quadrantectomy surgery.
- Conditions
- Intercostal Nerve Block, Pulmonary Ventilation, Anesthesia, Local, Breast Neoplasms
- Trial name
- EIT (NCT07079436)
- Testing
- 0.25% ropivacaine, 0.375% Ropivacaine, 0.5% Ropivacaine
- Where
- China
- Volunteers
- 67 people
- Sponsor
- Fudan University
Prolonged Air Leak, Post-operative Pain
Phrenic Nerve Infiltration: Pulmonary Expansion and Pain Control
Between January 2021-2023, 65 consecutive patients at risk for PAL (defined in accordance to "2019 Society of Thoracic Surgery score-criteria of PAL") underwent lung resection (lobectomy or sublobar resection) for malignancy.
- Trial name
- NCT06356038
- Testing
- intra-operative phrenic nerve infiltration
- Where
- Italy
- Volunteers
- 66 people
- Sponsor
- Azienda Ospedaliera "Sant'Andrea"
Osteoarthritis, Knee
Blood Levels of Local Anaesthetic in Knee Arthroplasty Using a Continuous Infusion Device
The primary goal is to evaluate ropivacaine blood concentrations during and after local anaesthetic (ropivacaine) infiltration - the Caledonian technique - for total knee replacement surgery.
- Trial name
- BLOCKS-II (NCT01935648)
- Testing
- Ropivacaine
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Golden Jubilee National Hospital
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