Clinical trials: Ropivacaine
Postpartum Depression
Effects of Epidural Labor Analgesia With Esketamine on the Incidence of Postpartum Depression in Parturients
Postpartum depression is a common psychological abnormality during the puerperium, which seriously affects maternal and neonatal health.
- Trial name
- NCT05826327
- Testing
- Esketamine, Sufentanil
- Where
- China
- Volunteers
- 364 people
- Sponsor
- Women's Hospital School Of Medicine Zhejiang University
Hypotension, Pain
The Prevention of Hypotension After Epidural Analgesia After Major Surgery
Epidural analgesia via continuous epidurally infused local anesthetic agent (LA) is widely and very successfully used routinely for perioperative pain control in patients undergoing major orthopedic and abdominal surgery since…
- Trial name
- NCT02722746
- Testing
- Ropivacaine, Epinephrine
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- University of Florida
Abdominal Surgery, Postoperative Pain
External Oblique Intercostal Plane Block for Postoperative Analgesia After Major Upper Abdominal Surgery
Postoperative pain after laparoscopic major upper abdominal surgery (e.g., gastric, hepatic, gallbladder, pancreatic surgery) is often severe, and inadequate analgesia may lead to increased opioid use, opioid dependence, and poor…
- Trial name
- NCT07331441
- Testing
- External Oblique Intercostal Plane Block, Standard multimodal analgesia
- Where
- China
- Volunteers
- 78 people
- Sponsor
- Jun Zhang
Diabetes Mellitus, Type 2
To Observe the Clinical Effect of Femoral Nerve Block With Low Concentration of Ropivacaine Based on DPN Grading
The purpose of this study was to quantitatively standardize the performance of patients with DPN with different course of disease using high-frequency ultrasound, and to design experiments to verify the conclusion that DPN…
- Trial name
- NCT06732362
- Testing
- Different DPN ratings
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Zheng Guo
Dose-Response Relationship, Drug
Effect of Perineural Dexmedetomidine on the ED50 Ropivacaine for Brachial Plexus Blocks in Pediatric Patients: a Randomized Trial
Dexmedetomidine can prolong the duration of local anesthetics, but the effect of perineural dexmedetomidine on the potency of ropivacaine for brachial plexus blocks in pediatric patients has not been investigated.
- Trial name
- NCT02781246
- Testing
- perineural dexmedetomidine
- Volunteers
- 160 people
- Sponsor
- Guangzhou Women and Children's Medical Center
Pain
A Safety and Effectiveness Pilot Study of PRF-108 and PRF-110 in Healthy Volunteers
This is a clinical study testing PRF-108 and PRF-110 (a new extended release 4% gel formulations of ropivacaine) in an experimentally induced pain model in healthy volunteers.
- Trial name
- NCT00883194
- Testing
- PRF-108, Ropivacaine, PRF-110
- Where
- Israel
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- PainReform LTD
Ambulatory Plastic Surgery, Esthetic Prosthetic Breast Expansion
Pectoral Nerve Block for Analgesia After Breast Augmentation
Breast augmentation is among the most popular surgical procedures performed in the world with approximately 1,773,584 performed in 2013. This surgical intervention generates important pains during postsurgical recovery.
- Trial name
- PECS B&BS (NCT02682186)
- Testing
- Ropivacaine after dilution with sodium chloride 0.9%
- Where
- 3 sites in France
- Volunteers
- 74 people
- Sponsor
- University Hospital, Montpellier
Knee Arthroplasty
Comparing Two Regional Anesthesia Interventions for Knee Arthroplasty.
Osteoarthritis of the knee is a common disease of the elderly and knee arthroplasty is indicated in severe cases to improve long term pain and function.
- Trial name
- NCT03944005
- Where
- 2 sites in Canada, United Kingdom
- Sponsor
- Western University, Canada
Anesthesia, Anesthesia Recovery Period
Effect of Epidural Anesthesia and Analgesia on Quality of Recovery After Radical Prostatectomy.
Postoperative quality of recovery (QoR) could be related to anesthesia and postoperative analgesia. This study is exploring early QoR after radical prostatectomy in the two groups of anesthesia.
- Conditions
- Anesthesia, Anesthesia Recovery Period, Radical Prostatectomy, Patient Satisfaction
- Trial name
- QoR (NCT04587505)
- Testing
- Epidural anesthesia with light general anesthesia, Postoperative epidural analgesia, General anesthesia
- Where
- Croatia
- Volunteers
- 61 people
- Sponsor
- University Hospital of Split
Postoperative Pain, Shoulder Surgery
The Addition of Sufentanil Interscalene Block in Shoulder Surgery
The purpose of this study is to compare the effects and side effects of interscale block performed with Naropin 0.1% cum sufentanil or Naropin 0.1% in shoulder surgery.
- Trial name
- NCT01025102
- Testing
- Naropin 0.1% cum sufentanil
- Where
- Denmark
- Volunteers
- 26 people
- Sponsor
- Bent Gymoese Jorgensen
Colorectal Surgery, TAP Blocks
TAP Block Catheters vs Liposomal Bupivacaine for Pain Control After Colorectal Surgery
This is a prospective randomized study designed to compare the pain control from a single shot of liposomal bupivacaine (Exparel) against transversus abominus plane (TAP) catheters with ropivicaine bolus in patients undergoing…
- Trial name
- NCT03080142
- Testing
- Exparel, Ropivacaine
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- University of California, Davis
Cardiac Surgery Patients
High-dose Opioid Versus Opioid-sparing Anaesthesia in Cardiac Surgery
BACKGROUND In cardiac surgery, high-dose opioid contributes to adverse events associated with poor postoperative outcomes. There is growing evidence that nerve block-based multi-modal anesthesia protocols may reduce…
- Trial name
- NCT06437886
- Testing
- opioid-sparing protocol
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
Kidney Transplant; Complications, Pain, Postoperative
Postoperative Pain Control Following Renal Transplant
This study aims to compare the effectiveness of a regional anesthetic block vs systemic intravenous (IV) lidocaine in controlling post-operative pain in kidney transplantation patients.
- Trial name
- NCT05044429
- Testing
- Intravenous Lidocaine, Transversus abdominis plane (TAP) block, Quadratus Lumborum (QL) Block
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- George Washington University
Colorectal Cancer, Colorectal Surgery
Peripheral Autonomic Block (BAP) Plus Transversus Abdominis Plane Block (TAP) for Postoperative Analgesia After Minimally Invasive Left-Sided Colorectal Resection (BAPTAP)
Effective postoperative pain management is essential for enhanced recovery after laparoscopic colorectal surgery. This randomized, controlled, double-blind trial will compare conventional postoperative analgesia (intravenous…
- Conditions
- Colorectal Cancer, Colorectal Surgery, Anesthesia, Autonomic Nerve Block
- Trial name
- BAPTAP (NCT07388953)
- Testing
- Minimally Invasive Left-Sided Colorectal Resection, BAPTAP (Peripheral Autonomic Blockade + TAP Block), Trocar/Incision Infiltration
- Where
- Brazil
- Volunteers
- 140 people
- Sponsor
- Faculdade de Ciências Médicas de Minas Gerais
Epidural Top-up, Labour
Labour Epidural Top-up With Warmed Ropivacaine
The purpose of this study is to determine weather using warmed (body temperature) 0.75% Ropivicaine to convert labour epidural analgesia to surgical anaesthesia, reduces the onset time of surgical block, compared to standard room…
- Conditions
- Epidural Top-up, Labour, Caesarian Section, Ropivacaine
- Trial name
- LETWR (NCT02838329)
- Testing
- warming of ropivacaine for BT, Ropivicaine
- Where
- United Kingdom
- Volunteers
- 90 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Pain, Postoperative, Ankle Fractures
Efficacy of Multimodal Periarticular Injections in Operatively Treated Ankle Fractures
The purpose of this study is to determine the efficacy and safety of a peri-articular multimodal injection for post-operative pain control following operative management of closed, rotational ankle fractures.
- Trial name
- NCT02967172
- Testing
- Ropivacaine, Epinephrine, Morphine
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Iowa
Pain, Postoperative, Anesthesia
Effectiveness of Ultrasound-guided Scalp Block for Supratentorial Craniotomy
Pain management in patients undergoing neurosurgery is a very important issue. The effectiveness of USG-guided scalp blocks for pain management in craniotomy surgery is currently not known.
- Trial name
- NCT06127628
- Testing
- Ultrasound-guided scalp block with ropivacaine 0.375%
- Where
- Malaysia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Malaysia Sarawak
Postoperative Pain
Efficacy of Dexmedetomidine on Postoperative Analgesia
This prospective, randomized, double-blind study is designed to evaluate the postoperative analgesic efficacy of dexmedetomidine as an adjunct to ropivacaine in erector spinae block in patients undergoing radical mastectomy.
- Trial name
- EDPARMRCT (NCT05110339)
- Testing
- Ropivacaine plus dexmedetomidine, Ropivacaine
- Where
- Mexico
- Volunteers
- 28 people
- Sponsor
- Universidad Autónoma de Tamaulipas
Hip Osteoarthritis
Lumbar Plexus vs Quadratus Lumborum Block in Post-operative Pain Following Total Hip Replacement
The Lumbar Plexus (LP) block is currently used as the standard-of-care regional anesthesia technique to provide postoperative pain management after primary hip replacement surgery at UPMC Shadyside Hospital.
- Trial name
- NCT03801265
- Testing
- Lumbar plexus block, Quadratus lumborum type 3 block, Ropivacaine injection
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Sharad Khetarpal
Elective Reconstructive Surgery, Pain, Post Operative
The Efficacy and Safety of Lower Limb Nerve Blocks in Postoperative Analgesia for the Free Flap Donor Sites
The use of free fibular flaps and anterolateral thigh (ALT) flaps for repairing the oromandibular defects is well established, whereas few attentions were focused on postoperative analgesia for the donor area.
- Trial name
- NCT03071185
- Testing
- femoral nerve block, common peroneal nerve block
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Xia Zhang
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.