Clinical trials: Ropivacaine
Pain Management
Epidural Injection of Corticosteroids Under USG (EICUS)
Qualitative and quantitatively evaluate the pain control and incidence of adverse effects in patients undergoing corticosteroid infiltration and local anesthetic through sacral epidural puncture with ultrasound assistance or…
- Trial name
- EICUS (NCT02860078)
- Testing
- Ultrasound, Radioscopy
- Where
- Brazil
- Sponsor
- University of Sao Paulo General Hospital
Pain Management, Pain, Postoperative
Intrathecal Morphine Injection Versus Continuous Wound Infiltration After Pancreaticoduodenectomy
This is a prospective randomized open-label noninferiority trial that compares intrathecal morphine injection and continuous wound infiltration after open pancreaticoduodenectomy.
- Trial name
- ITM_PPPD (NCT06761989)
- Testing
- Intrathecal morphine injection, Continuous wound infiltration
- Where
- South Korea
- Volunteers
- 104 people
- Sponsor
- Seoul National University Hospital
Hip Osteoarthritis
PENG Block and Delirium After Hip Arthroplasty
Postoperative delirium is a common and serious complication in older adults undergoing total hip arthroplasty, associated with prolonged hospitalization, increased morbidity, delayed rehabilitation, and long-term cognitive…
- Trial name
- NCT07449468
- Testing
- 0.2% ropivacaine
- Where
- Poland
- Volunteers
- 180 people
- Sponsor
- Poznan University of Medical Sciences
Hernia Repair, Hernia Inguinal
Postsurgical Analgesia After Hernia Repair
The study is designed to evaluate the safety, efficacy, and pharmacokinetics (PK) of three ascending doses of AMT-143 to determine the appropriate dose of AMT-143 for the management of postsurgical pain following inguinal hernia…
- Conditions
- Hernia Repair, Hernia Inguinal, Hernia Surgery, Hernia, Inguinal/Surgery
- Trial name
- NCT06709612
- Testing
- AMT-143, ropivacaine
- Sponsor
- AmacaThera Inc.
Post Operative Pain
Optimal Effective Local Anesthetic Volume for Pain Relief Using Brachial Plexus Block
Prospective, patient-blinded study utilizing a novel Continuous Reassessment Method that concomitantly considers both block success and block side effects (lung dysfunction) for brachial plexus nerve blocks.
- Trial name
- NCT05868993
- Testing
- Dose of 0.5% Ropivacaine
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Benaroya Research Institute
Spinal Anesthetic Toxicity
Echocardiography and Spinal Induced Hypotension.
Modern guidelines have combined both the maximum diameter of IVC at expiration (dIVC max) and the IVCCI to appreciate right atrial pressure (RAP) measurements and consequently to assess intravascular volume status.
- Trial name
- NCT04001881
- Testing
- Transthoracic echocardiography, Spinal anesthesia
- Where
- Greece
- Volunteers
- 61 people
- Sponsor
- Attikon Hospital
Obstetric Pain, Other Complications of Obstetric Anesthesia - Delivered
Epidural Dexamethasone for Labor Analgesia: the Effects on Ropivacaine Consumption and Labour Outcome
To assess the efficacy of epidural dexamethasone administration, compared to placebo, in reducing local anesthetics consumption during labor epidural analgesia in parturient women
- Trial name
- DEXAPER (NCT02857465)
- Testing
- Dexamethasone, Ropivacaine, Sufentanil
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Pain Management, Pain, Postoperative
Preperitoneal Analgesia Versus Epidural Analgesia After Open Pancreaticoduodenectomy
This is a prospective randomized open-label noninferiority trial that compares thoracic epidural analgesia and continuous preperitoneal analgesia after open pancreaticoduodenectomy.
- Trial name
- Pain (NCT04375826)
- Testing
- Epidural patient controlled analgesia, Preperitoneal analgesia and IV-PCA
- Where
- South Korea
- Volunteers
- 146 people
- Sponsor
- Seoul National University Hospital
Pain After Abdominal Surgery
A Clinical Trial Evaluating the Efficacy, Safety, and Pharmacokinetic Profile of TRD303 for Postoperative Analgesia After Abdominal Surgery in China.
A multicenter, randomized, double-blind, placebo-positive, parallel-controlled, phase Ⅲ clinical trial of the efficacy, safety and pharmacokinetics of TRD303 solution for postoperative analgesia in patients undergoing abdominal…
- Trial name
- NCT07353307
- Testing
- TRD303 solution, Ropivacaine hydrochloride, 0.9 % sodium chloride
- Where
- 2 sites in China
- Volunteers
- 333 people
- Sponsor
- The Third Xiangya Hospital of Central South University
Pain, Nerve Block
The Effect of Bilateral Infraorbital and Infratrochlear Nerve Block on Perioperative Period of Hypophysectomy
The endoscopic binostril transnasal transsphenoidal resection of pituitary procedures often cause intense pain which is difficult to suppress at the depth of conventional general anesthesia, resulting in severe hemodynamic…
- Trial name
- NCT05555147
- Testing
- nerve block with 0.5% ropivacaine, without any nerve block
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Tongji Hospital
Video Assisted Thoracoscopic Surgery, Lobectomy
SERRATHOR TRIAL : Interest of the Novel Serratus Plane Block in Post Operative Analgesia After Video-Assisted Thoracoscopic Lobectomy
Pain after thoracic surgery remains a challenge for anesthetists. Although VATS for lobectomy is associated with fewer complications compared to thoracotomy, pain after VATS needs to be treated with opioids.
- Conditions
- Video Assisted Thoracoscopic Surgery, Lobectomy, Pain Post Operative, Regional Anesthesia
- Trial name
- SERRATHOR (NCT03867695)
- Testing
- Ropivacaine, sterile saline
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Strasbourg, France
Adolescent Idiopathic Scoliosis (AIS), Neuromuscular Scoliosis
The Effect of Erector Spinae Plane Block (ESPB) on Pediatric Pain Management Following Posterior Spinal Fusion (PSF) Surgery
This study is being done to better understand the efficacy of an erector spinae plane block (ESPB) in pain management for children with Adolescent Idiopathic Scoliosis or Neuromuscular Scoliosis undergoing Posterior Spinal Fusion…
- Conditions
- Adolescent Idiopathic Scoliosis (AIS), Neuromuscular Scoliosis, Adolescent Idiopathic Scoliosis
- Trial name
- ESPB (NCT07561827)
- Testing
- Ropivacaine Hydrocloride
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- University of California, San Francisco
Supratentorial Tumors
Comparison of Systemic Opioid (Morphine) and Pre-Incision Bilateral Scalp Nerve Block for Pain Management in Craniotomy Patients
The goal of this randomized controlled clinical trial is to compare the effectiveness of systemic opioids versus pre-incision bilateral scalp nerve block in managing intraoperative noxious stimuli and postoperative pain in adult…
- Trial name
- NCT07425678
- Testing
- Scalp nerve block, Morphine, Lidocaine
- Where
- Pakistan
- Volunteers
- 62 people
- Sponsor
- Aga Khan University
Acute Pain
Paravertebral Catheter for Lung Transplant
This is a prospective observational trial of patient undergoing lung transplantation who have a thoracic paravertebral catheter(s) placed for postoperative pain control.
- Trial name
- NCT02380417
- Testing
- paravertebral catheter placement, 0.2% ropivacaine, Elastomeric pump
- Volunteers
- 33 people
- Sponsor
- University of Minnesota
Brachial Plexus Block
Dexamethasone Compared With Dexmedetomidine as an Adjuvant to Ropivacaine for Supraclavicular Brachial Plexus Block
The investigators want to compare the effectiveness of dexamethasone and dexmedetomidine as an adjuvant to 0.5% ropivacaine for supraclavicular brachial plexus block on the onset of block and duration of analgesia, so that the…
- Trial name
- NCT02787018
- Testing
- Ropivacaine and Normal saline, Ropivacaine and Dexamethasone, Ropivacaine and Dexmedetomidine
- Where
- Nepal
- Volunteers
- 120 people
- Sponsor
- B.P. Koirala Institute of Health Sciences
Incisional Pain
Continuous Transversus Abdominis Plane Nerve Block for Postoperative Analgesia
Research study to determine if putting local anesthetic through one or two tiny tubes next to the nerves that go to the area the patients are having surgery on (abdomen or pelvis), will improve pain control following surgery.
- Trial name
- NCT00944151
- Testing
- TAP Catheter and Infusion of Study Solution
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, San Diego
Coronary Artery Disease
Epidural Anesthesia and Postoperative Analgesia With Ropivacaine and Fentanyl
The aim of the present study was to assess the efficacy of thoracic epidural anesthesia followed by postoperative epidural infusion and patient-controlled epidural analgesia with ropivacaine/fentanyl in off-pump coronary artery…
- Trial name
- NCT01384175
- Testing
- intravenous analgesia, epidural infusion, patient-controlled epidural analgesia
- Where
- Russia
- Volunteers
- 93 people
- Sponsor
- Northern State Medical University
Arthropathy of Knee
Adductor Canal Block Versus Femoral Nerve Block for Total Knee Arthroplasty
Peripheral nerve blocks catheters of the femoral nerve have long been used for perioperative analgesia in total knee arthroplasty (TKA). These blocks provide effective analgesia and patient satisfaction for surgical pain relief.
- Trial name
- NCT03133481
- Testing
- Adductor Canal Nerve Block, Femoral Nerve Block
- Where
- United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Arthroplasty, Replacement, Knee, Total Knee Arthroplasty
Systemic Lidocaine Versus Ultrasound-guided Adductor Canal Block for Patients Undergoing Total Knee Arthroplasty
The investigators are evaluating the postoperative outcomes in patients undergoing total knee arthroplasty that receive either systemic lidocaine or ultrasound-guided adductor canal block as part of their anesthetic plan.
- Trial name
- ACBSL (NCT04828083)
- Testing
- Lidocaine IV, Saline IV
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Rhode Island Hospital
Pain, Osteoarthritis
Early Ambulation After Adductor Canal Block for Total Knee Arthroplasty
The purpose of this study is to assess early ambulation following total knee replacement in patients receiving continuous adductor canal block with posterior capsular injection compared to continuous femoral nerve block with…
- Trial name
- NCT01459861
- Testing
- Canal Block and Capsular Injection, Femoral Nerve Block with Tibial Nerve Block
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Trinity Health Of New England
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