Clinical trials: Ropivacaine
Postoperative Pain, Postoperative Complications
Local Anesthetic Automated Intermittent Administration vs. Continuous Infusion Via Femoral Nerve Block.
This study evaluates the impact of local anesthetic administration regiment through peri-neural femoral nerve catheter on pain and motor block frequency, after total knee arthroplasty.
- Trial name
- NCT03696095
- Testing
- Ropivacaine Hcl 0.2% Inj Bag 200Ml (PIB mode), Ropivacaine Hcl 0.2% Inj Bag 200Ml (CI mode)
- Where
- Belgium
- Volunteers
- 70 people
- Sponsor
- J P Lecoq
Uniportal Video-assisted Thoracic Surgery
Optimization of Perioperative Analgesia Protocol for Uniportal Video-assisted Thoracoscopic Surgery
Trial design Despite video-assisted thoracic technology and procedure specific postoperative pain management (PROSPECT) have been promoted through recent years, thoracic surgery is still considered to be one of the most painful…
- Trial name
- NCT06016777
- Testing
- Ultrasound-guided paraspinal block and patient-controlled intravenous analgesia pump, Ultrasound-guided erector spinal block and patient-controlled intravenous analgesia pump, Patient-controlled intravenous analgesia pump
- Where
- China
- Volunteers
- 102 people
- Sponsor
- China-Japan Friendship Hospital
Radius Fracture Distal, Rebound Pain
Ropivacaine Concentration and Rebound Pain
The goal of this clinical trial is to see if the concentration of a local anesthetic (ropivacaine) in peripheral nerve block is related to the severness of pain after surgery of distal radius fractures in adults.
- Trial name
- NCT06950372
- Testing
- Ropivacaine concentration low, Ropivacaine concentration high
- Where
- Norway
- Volunteers
- 80 people
- Sponsor
- Oslo University Hospital
Caesarean Section
Ropivacaine 0.75% Versus Levobupivacaine 0.5% for Conversion of Labour Epidural
The aim of this trial is to compare the local anaesthetic ropivacaine to local anaesthetic levobupivacaine in converting the standard patient controlled labour epidural to provide anaesthesia for an emergency Caesarean section.
- Trial name
- RoLe (NCT01160965)
- Testing
- 0.5% levobupivacaine, 0.75% Ropivacaine
- Where
- United Kingdom
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Breast Neoplasm
Regional Anesthesia and Partial Mastectomy
Pectoralis nerves plane block (PECS) first described by Blanco in 2011 has become part of postoperative pain management in breast surgery, thoracic surgery and thoracic trauma.
- Trial name
- NCT04824599
- Testing
- PECS II, Local anesthetic infiltration, Subcutaneus local anesthetic infiltration
- Where
- Sweden
- Volunteers
- 60 people
- Sponsor
- Karlstad Central Hospital
Postoperative Pain, Cerebral Palsy
Postoperative Pain in Children With Cerebral Palsy After Pelvic and Femoral Osteotomies
This study is a comparison of postoperative pain in children with cerebral palsy after surgery on the hip or femur. One group is treated with p.o.
- Trial name
- NCT00964639
- Testing
- Ropivacaine, Saline
- Where
- Denmark
- Volunteers
- 12 people
- Sponsor
- University of Aarhus
Rotator Cuff Injury
Comparison of Paracoracoid Subscapularis Plane Block to Interscalene Block for Arthroscopic Shoulder Surgery
One hundred and twenty patients will be randomized to Interscalene block or Paracoracoid Subscapularis plane block. The study will evaluate the efficacy and duration of blocks in the 2 groups with regards to postoperative…
- Trial name
- SPBvsISB (NCT03073928)
- Testing
- Interscalene Block, Paracoracoid SPB, Ropivacaine
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Chronic Pain, Acute Pain
Regional Anesthesia for Thyroidectomy
For more than 25 years, Regional Anesthesia has challenged anesthesiologists to determine whether it offers real benefits in terms of patient outcome from major surgery, compared with general anesthesia.
- Trial name
- NCT02108834
- Testing
- nerve block
- Where
- 2 sites in China
- Volunteers
- 79 people
- Sponsor
- Guangzhou First People's Hospital
Lung Cancer
Mid-transverse Process Combined With Erector Spinae Block Versus Paravertebral Plane Block
This study aims to compare efficacy of Mid-transverse process to pleura block combined with erector spinae block versus paravertebral plane block in cancer patients undergoing thoracotomy surgeries.
- Trial name
- NCT06618599
- Testing
- Mid-transverse process to pleura block combined with erector spinae block, paravertebral block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Post Operative Pain
A Study to Evaluate the Safety, Pharmacokinetics and Preliminary Efficacy of PRF110 in Bunionectomy Surgery
PRF110 is new extended release oily solution formulation of ropivacaine that is intended for local infiltration into surgical wounds.
- Trial name
- NCT02784327
- Testing
- PRF110
- Where
- 2 sites in Israel
- Volunteers
- 15 people
- Sponsor
- PainReform LTD
Pain Control
Trans-Abdominis Plane Block Efficacy for Post-Cesarean Section Pain
The primary aim of this study is to measure the magnitude and duration of trans-abdominis plane (TAP) block analgesia in parturients undergoing elective cesarean section with concurrent standard of care operative analgesic…
- Trial name
- NCT00945620
- Testing
- ropivicaine
- Where
- United States
- Sponsor
- Vanderbilt University
Hip Arthroplasty, Hip Pain
Optimizing Local Anesthetic Concentration for Continuous Lumbar Plexus Nerve Blocks
This is a research study to determine if the concentration of local anesthetic through a catheter next to the nerves that go to the hip that is undergoing surgery, affects muscle strength and sense of touch experienced after…
- Trial name
- NCT00912873
- Testing
- 0.1% Ropivacaine, 0.4% Ropivacaine
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of California, San Diego
Anesthesia
Study Measuring Total Plasma Ropivacaine Levels During Continuous Peripheral Nerve Catheter Infusion
The purpose of the study is to measure the blood levels of the medicine called ropivacaine (local anesthetic) used to manage pain.
- Trial name
- NCT01718262
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Defense and Veterans Center for Integrative Pain Management
Popliteal Nerve Block, Foot Surgery
Effect of Ropivacaine During Popliteal Nerve Block in Foot and Ankle Surgery
With the increasing rise of outpatient surgery in orthopaedic procedures, the management of immediate postoperative pain has been a major topic investigated, with the use of a peripheral nerve block in combination with general…
- Conditions
- Popliteal Nerve Block, Foot Surgery, Ankle Surgery
- Trial name
- NCT04872322
- Testing
- Ropivacaine 0.5% Injectable Solution, Ropivacaine 0.25% Injectable Solution, Percocet Pill
- Where
- United States
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Rothman Institute Orthopaedics
Post-operative Pain, Anesthesia, Local
Evaluation of the Analgesic Benefit of Adding the Blocks of the Intermediate and Medial Femoral Cutaneous Nerves in Addition to the Femoral Triangle Block for Postoperative Analgesia After a Knee Replacement Surgery
Total knee replacement surgery can be associated with a significant postoperative pain burden and an inability to mobilize adequately, which can lead to the failure of the ambulatory course.
- Trial name
- NCT06038851
- Testing
- Para-Sartorial Compartments (PACS) Block, Femoral Triangle Block (FTB), Infiltration between popliteal artery and capsule of the knee (IPACK) block
- Where
- Canada
- Volunteers
- 122 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Nephrectomy, Analgesia
Thoracic Paravertebral Blocks in Open Nephrectomy
60 patients ASA I-III, undergoing open nephrectomy will be randomly assigned into one of two groups, namely group A (n=30), where a thoracic paravertebral block will be performed preoperatively and a paravertebral catheter for…
- Trial name
- NCT03428633
- Testing
- Ropivacaine, Morphine
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- Asklepieion Voulas General Hospital
Post-Dural Puncture Headache, Ganglion Sphenopalatine Block
The Effect of Ganglion Sphenopalatine Block (GSP-block) Follow-Up
The purpose of this study is to evaluate the long term effects of the ganglion sphenopalatine block (GSP block) on postdural puncture headache.
- Trial name
- GSP-FOLLOW (NCT05301387)
- Testing
- Ganglion Sphenopalatine Block
- Where
- Denmark
- Volunteers
- 38 people
- Sponsor
- University Hospital Bispebjerg and Frederiksberg
Pain, Pain Management Following Cardiopulmonary Bypass Surgery
Addition of Dexmedetomidine to Ropivacaine in Bilateral Erector Spinae Plane Block in Patients Undergoing Coronary Artery Bypass Surgery
Coronary artery bypass surgery (CABG), typically performed through a median sternotomy, causes significant postoperative pain. Managing this pain effectively while reducing reliance on opioids is essential, as opioids can lead to…
- Conditions
- Pain, Pain Management Following Cardiopulmonary Bypass Surgery, Erector Spinae Plane Block
- Trial name
- NCT06981949
- Testing
- Dexmedetomidine, Ropivacaine
- Volunteers
- 110 people
- Sponsor
- Lebanese American University
Total Knee Arthroplasty
IPACK Block in Total Knee Arthroplasty
100 patients ASA I-III, undergoing total knee arthroplasty under spinal anesthesia, will be randomly assigned into one of two groups, namely group A (n=50), where an adductor canal block and an IPACK block will be performed…
- Trial name
- NCT03692858
- Testing
- Adductor Canal Block plus IPACK Block, Adductor Canal Block
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- Asklepieion Voulas General Hospital
Postoperative Pain
Does ESPB Improve Postoperative Quality of Recovery After VATS
Video-Assisted Thoracoscopic Surgery (VATS) is a minimally invasive surgery. Despite reduced surgical trauma compared to the traditional thoracotomy approach, pain control after VATS remains challenging.
- Trial name
- NCT03756987
- Testing
- Ropivacaine Injection, Normal saline
- Where
- China
- Volunteers
- 76 people
- Sponsor
- Fujian Provincial Hospital
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