Clinical trials: Ropivacaine
Lung Neoplasms
Erector Spinae Plane Block Versus Paravertebral Block During Non-intubated Thoracoscopic Lung Resections.
A randomized prospective trial to test the non-inferiority of Erector Spinae Plane Block (ESPB) in comparison with paravertebral block during non-intubated thoracoscopic lung resection
- Trial name
- PABATS (NCT03137576)
- Testing
- Paravertebral Block (PVB), Erector Spinae Plane Block (ESPB)
- Where
- Italy
- Volunteers
- 7 people
- Sponsor
- IRCCS Sacro Cuore Don Calabria di Negrar
Hallux Valgus, Anesthesia
The Effects of Various Concentrations of Ropivacaine on the Onset and Duration of Ankle Blocks
Peripheral nerve blocks are essential in ensuring effective regional anesthesia and postoperative analgesia in forefoot surgery for hallux valgus repair, with or without minor concomitant toe procedures.
- Trial name
- ROADS (NCT06185608)
- Testing
- 0.25% ropivacaine, 0.5% ropivacaine, 1% ropivacaine
- Where
- Belgium
- Volunteers
- 174 people
- Sponsor
- Ziekenhuis Oost-Limburg
Injury of Anterior Cruciate Ligament
Adductor Canal Block: Continuous Infusion Versus Automatic Intermittent Bolus
The aim of this prospective, randomized , blinded study is to compare two different infusion techniques (continuous VS intermittent automatic bolus) to assess the effects of postoperative analgesia after Day-Case anterior…
- Trial name
- NCT02589288
- Testing
- Continuous Infusion of ropivacaine 0.2%, Automatic Intermittent Bolus of ropivacaine 0.2%
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- ASST Gaetano Pini-CTO
Chronic Postoperative Pain
A Comparative Effect of Echogenic Needle for Nerve Block on Acute and Chronic Postoperative Pain
Surgical pain is a common complication after surgery, affecting patient recovery and treatment quality. >20% of patients suffer from chronic postoperative pain. China has >70 million surgeries yearly.
- Trial name
- NCT06281431
- Testing
- Echogenic nerve block needle, Non-echogenic nerve block needle
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- The Second Affiliated Hospital of Chongqing Medical University
Knee Arthroplasty
Comparing Two Regional Anesthesia Interventions for Knee Arthroplasty.
Osteoarthritis of the knee is a common disease of the elderly and knee arthroplasty is indicated in severe cases to improve long term pain and function.
- Trial name
- NCT03944005
- Where
- 2 sites in Canada, United Kingdom
- Sponsor
- Western University, Canada
Postoperative Pain
QLESP Block in Hip Surgery
Total hip arthroplasty (THA) is a common surgical procedure aiming to improve mobility and quality of life in patients suffering from hip pain.
- Trial name
- NCT05998954
- Testing
- transmuscular quadratus lumborum and modified erector spinae plane (QLESP) block, suprainguinal fascia iliaca block
- Where
- China
- Sponsor
- Huazhong University of Science and Technology
Arthroplasty, Replacement, Knee, Nerve Block
The Efficacy of Automated Intermittent Boluses for Continuous Femoral Nerve Block: a Prospective, Randomized Comparison to Continuous Infusions
The optimal infusion technique (continuous rate vs. intermittent bolus) for peripheral nerve blocks has not been established. To our knowledge, this is the first study to compare the efficacy of an automated intermittent bolus…
- Trial name
- NCT01226927
- Testing
- Automated intermittent bolus
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Medical University of South Carolina
Rotator Cuff Injuries, Anesthesia; Functional
The Impact of a Preoperative Nerve Block on the Consumption of Sevoflurane in Total Shoulder Arthroplasty
Total arthroplasty surgery of the shoulder is performed under general anesthesia. Pain control for after the surgery can be achieved purely with intravenous and oral pain medication or in combination with freezing of the nerves.
- Trial name
- NCT04020601
- Testing
- Ropivacaine, Dextrose
- Where
- Canada
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Multimodal Analgesia, Cesarean Section
TAP Using Dexmedetomidine and Ropivacaine for Cesarean Section Analgesia
To evaluate the effect of dexmedetomidine as an adjuvant of ropivacaine in the TAP block on cesarean section parturients under multimodal analgesia, optimize the multimodal analgesia program for cesarean section, and guide…
- Trial name
- NCT05700045
- Testing
- Dexmedetomidine
- Where
- 2 sites in China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Laparoscopic Gastrectomy, Ropivacaine
Effect of Intraperitoneal Ropivacaine on Visceral Pain After Laparoscopic Gastrectomy
Visceral pain is obvious and lasts for a long time in patients after laparoscopic gastrectomy.Relieving the visceral pain is of great significance for patients' postoperative emotional experience, functional recovery and reducing…
- Trial name
- NCT06145945
- Testing
- 0.5% Ropivacaine, Saline
- Where
- China
- Volunteers
- 72 people
- Sponsor
- SanQing Jin
Postoperative Pain
Catheter-based Peripheral Regional Anesthesia After Total Knee Arthroplasty
BACKGROUND Total knee arthroplasty can be severely painful, and peripheral regional anesthesia is highly recommended as part of the perioperative pain treatment.
- Trial name
- API-KNEE (NCT03372265)
- Testing
- Ropivacaine 0.2%
- Where
- Denmark
- Volunteers
- 111 people
- Sponsor
- Nordsjaellands Hospital
Pain After Abdominal Surgery
A Clinical Trial Evaluating the Efficacy, Safety, and Pharmacokinetic Profile of TRD303 for Postoperative Analgesia After Abdominal Surgery in China.
A multicenter, randomized, double-blind, placebo-positive, parallel-controlled, phase Ⅲ clinical trial of the efficacy, safety and pharmacokinetics of TRD303 solution for postoperative analgesia in patients undergoing abdominal…
- Trial name
- NCT07353307
- Testing
- TRD303 solution, Ropivacaine hydrochloride, 0.9 % sodium chloride
- Where
- 2 sites in China
- Volunteers
- 333 people
- Sponsor
- The Third Xiangya Hospital of Central South University
Intercostal Nerve Block
Intercostal Nerve Block With Local Anesthesia Administered Via Incision-specific Multi-site Injection for Thoracic Surgery
The goal of this clinical trial is to test analgesic effect of intercostal nerve block in different range. The main question it aims to answer are: question 1: whther incision-specific multi-site injection (ISMSI, from the 3rd to…
- Trial name
- NCT06011044
- Testing
- Intercostal Nerve Block
- Volunteers
- 60 people
- Sponsor
- Bixin Wen
Lung Cancer
Mid-transverse Process Combined With Erector Spinae Block Versus Paravertebral Plane Block
This study aims to compare efficacy of Mid-transverse process to pleura block combined with erector spinae block versus paravertebral plane block in cancer patients undergoing thoracotomy surgeries.
- Trial name
- NCT06618599
- Testing
- Mid-transverse process to pleura block combined with erector spinae block, paravertebral block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Postoperative Pain, Liposomal Bupivacaine
Efficacy of Liposomal Bupivacaine for Transversus Abdominis Plane Block
This is a single-center, randomized, single-blind, parallel-group clinical trial. The study aims to compare the analgesic efficacy of liposomal bupivacaine versus ropivacaine for transversus abdominis plane (TAP) block in…
- Trial name
- NCT07577934
- Testing
- Liposomal Bupivacaine TAP block, Ropivacaine TAP blocks
- Where
- China
- Volunteers
- 86 people
- Sponsor
- Tianjin First Central Hospital
Pediatric Extremity Fracture, Pediatric Extremity Soft Tissue Injury
Peripheral Nerve Blocks in Pediatric Orthopedic Patients
Context: Single shot peripheral nerve blocks have limited duration of action depending on the local anesthetic agent used in the block. But it rarely lasts longer than 12 hrs.
- Trial name
- NCT02236130
- Testing
- Regional block, General Anesthesia, Local Anesthetic Ropivacaine
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University of Mississippi Medical Center
Postoperative Pain
Continuous Pre-uterine Wound Infiltration Versus Intrathecal Morphine for Postoperative Analgesia After Cesarean Section
The cesarean section is considered as a painful surgery during the post operative period. Mothers may need to move immediately after the surgery to take care of their babies.
- Trial name
- NCT02279628
- Testing
- Ropivacaine, Morphine
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Central Hospital, Nancy, France
Dexamethasone, Dexmedetomidine
Dexamethasone and Dexmedetomidine as Adjuvants to Ropivacaine in Ultrasound-guided Multilevel Thoracic Paravertebral Block for Lobectomy: A Prospective, Randomized, Triple-blind Study
The hypothesis is whether perineural dexamethasone and dexmedetomidine prolonged the duration of analgesia as compared with either perineural dexamethasone or perineural dexmedetomidine after TPVB.
- Conditions
- Dexamethasone, Dexmedetomidine, Ropivacaine, Lobectomy
- Trial name
- NCT04763434
- Testing
- dexamethasone; dexmedetomidine; ropivacaine
- Volunteers
- 90 people
- Sponsor
- Gansu Provincial Hospital
Total Hip Arthroplasty (THA) or Total Knee Arthroplasty (TKA), Preoperative Adductor Canal Block (ACB)
The Impact of Regional Motor-sparing Blocks on Early Rehabilitation Following Primary Hip or Knee Arthroplasty
The purpose of this study is to determine whether a single nerve block given before surgery can help patients regain independence and mobility more quickly after planned hip or knee replacement surgery for osteoarthritis.
- Conditions
- Total Hip Arthroplasty (THA) or Total Knee Arthroplasty (TKA), Preoperative Adductor Canal Block (ACB), Preoperative Pericapsular Nerve Group (PENG)
- Trial name
- NCT07834619
- Testing
- PENG Block with Ropivacaine, Adductor Canal Block with Ropivacaine, Subarachnoid anesthesia
- Where
- Poland
- Volunteers
- 220 people
- Sponsor
- Poznan University of Physical Education
Nephrolithotomy, Percutaneous
ESP Block vs Control for Pain Control Following Percutaneous Nephrolithotomy
The purpose of this study is to investigate the use of the erector spinae (ESP) block in reducing the morphine milligram equivalent (MME) consumption post percutaneous nephrolithotomy. Objectives: 1.
- Trial name
- NCT05024344
- Testing
- Erector Spinae Plane Block, Ropivacaine 0.5% Injectable Solution, Dexamethasone
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- University of Tennessee Medical Center
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