Clinical trials: Ropivacaine
Acute Pain
Efficacy of Pericapsular Nerve Group Block
Hip fracture is a common orthpaedic problem especially in elderly population. Fascia iliaca compartment block (FICB) and femoral nerve block are well-established technique as part of peri-operative multimodal analgesia for hip…
- Trial name
- NCT05154318
- Testing
- Pericapsular Nerve Group Block, Fascia iliaca compartment block
- Where
- Hong Kong
- Volunteers
- 100 people
- Sponsor
- The University of Hong Kong
Pregnancy, Vaginal Delivery
The Impact of an Epidural Ropivacaine-Neostigmine Injection for Perineal Analgesia at the End of Labor.
Perineal pain after childbirth occurs in the majority of women (with or without episiotomy). Perineal pain can become source of chronic pain in 9%-12% of the cases.
- Trial name
- NCT00407290
- Testing
- neostigmine
- Where
- Belgium
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Diaphragmatic Paralysis
Ultrasound-guided Interscalene Block:3mL Ropi Provide Similar Analgesia to 5mL and Less Diaphragmatic Paralysis
Ropivacaine for ultrasound-guided interscalene block: 3mL provide similar analgesia to 5mL with less diaphragmatic paralysis in shoulder arthroscopy surgeries
- Trial name
- NCT04317235
- Testing
- Ropivacaine 0.5% Injectable Solution
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Saint George Hospital
Arthropathy of Knee Joint
Evaluation of Optimal Dose of Local Anesthetics for Patient Controlled Continuous Femoral Nerve Block
To evaluate an analgesic effect without basal administration of local anesthetics for patient-controlled femoral nerve block (with sciatic nerve block) after total knee arthroplasty.
- Trial name
- NCT01198340
- Testing
- PC-FNB with basal administration of local anesthetics, PC-FNB without basal local anesthetics
- Where
- Japan
- Volunteers
- 60 people
- Sponsor
- Okayama University
Labor Pain
Epidural Labor Analgesia and Infant Neurobehavior
Infant neurobehavior alteration is predictor of later intelligence development. Many factors would influence or are associated with infant neurobehavior, of which exist or appear during perinatal period.
- Trial name
- ELAIN (NCT00987441)
- Testing
- Ropivacaine and sufentanil
- Where
- China
- Volunteers
- 1,200 people
- Sponsor
- Nanjing Medical University
Disorder of Shoulder
Perfusion Index for Predicting Brachial Plexus Block Success Under General Anesthesia
This study was designed to determine whether the success or failure of interscalene brachial plexus block under general anesthesia can be predicted using perfusion index (PI).
- Trial name
- NCT04925505
- Testing
- Interscalene brachial plexus blocks with ultrasound guidance under general anesthesia
- Where
- South Korea
- Volunteers
- 70 people
- Sponsor
- Korea University Guro Hospital
Osteoarthritis
Comparison of Anesthetic Techniques on Total Hip Arthroplasty
To compare analgesia and orthopedic rehabilitation milestones in patients receiving either spinal anesthesia (local anesthetic plus opioid) or general endotracheal anesthesia with lumbar plexus block.
- Trial name
- NCT01359865
- Testing
- Lumbar Plexus Block
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Thoracic Surgery
Local Anesthetic as Single Shot Versus Catheter in Patients Undergoing Video Assisted Thoracoscopic Surgery
The purpose of this research is to compare a single shot long acting local anesthetic to catheter infusion of local anesthetic in patients undergoing video assisted thoracoscopic (VAT) surgery.
- Trial name
- NCT04559347
- Testing
- Liposomal Bupivacaine (EXPAREL®)/Bupivacaine, Ropivacaine (0.5% bolus followed by 0.2% infusion)
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Poovendran Saththasivam
Osteoarthritis, Total Knee Replacement
Adductor Canal Block
The investigators aim to investigate whether the addition of a surgeon-administered adductor canal blockade to a multimodal periarticular injection cocktail provides additional pain relief for patients undergoing total knee…
- Trial name
- NCT04513145
- Testing
- Ropivacaine injection, Saline Injection, Total Knee Arthroplasty
- Where
- United States
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- OrthoCarolina Research Institute, Inc.
Post-operative Pain, Gallstone Disease
Effects of Calot's Triangle Block for Postoperative Analgesia in Patients Undergoing Laparoscopic Cholecystectomy: a Prospective, Randomized, Double-blind, Controlled, Clinical Trial
Chronic pain after laparoscopic cholecystectomy (LC) is a common complication with an incidence ranging between 3-56%. In many cases, however, the cause chronic pain after LC remains unknown and visceral hyperalgesia and central…
- Trial name
- NCT02300480
- Testing
- CTB group, PCIA group
- Where
- China
- Volunteers
- 140 people
- Sponsor
- First Affiliated Hospital of Chongqing Medical University
Colorectal Cancer, Pain
Epidural Versus Patient-controlled Analgesia for Reduction in Long-term Mortality Following Colorectal Cancer Surgery
Colorectal cancer is one of the most common cancers in the industrialized world (12% of all cancers). In Sweden, 6000 new cases of colorectal cancer are reported each year, and almost half of these cases result in death.
- Conditions
- Colorectal Cancer, Pain, Other Complications
- Trial name
- EPICOL (NCT01318161)
- Testing
- Ropivacaine + opioid epidurally, Morphine
- Where
- 2 sites in Sweden
- Volunteers
- 221 people
- Sponsor
- Örebro University, Sweden
Pain, Postoperative, Osteoarthritis, Knee
Comparing Local Anesthetic Injections to Nerve Blocks for Pain Control After Total Knee Replacement
Why are we doing this study? People who have knee replacement surgery often feel pain afterward. Doctors use different methods to control this pain.
- Conditions
- Pain, Postoperative, Osteoarthritis, Knee, Arthroplasty, Replacement, Knee
- Trial name
- LIA-PNB-TKA (NCT07744503)
- Testing
- Continuous Femoral and Sciatic Nerve Block (Ropivacaine), Local Infiltration Analgesia (Ropivacaine, Ketorolac, Epinephrine)
- Where
- Austria
- Volunteers
- 78 people
- Sponsor
- Christopher Male
Surgical Procedures, Operative
The T REX Pilot Study: a Study to Investigate the Use of an Alternative Anaesthetic in Infants.
Animal studies suggest general anaesthetics harm the developing brain. It is unclear if these findings are relevant to humans but the issue has become a major concern.
- Trial name
- NCT02353182
- Testing
- Dexmedetomidine, Remifentanil, Bupivacaine
- Where
- 6 sites in United States, Australia and 1 more
- Volunteers
- 60 people
- Sponsor
- Murdoch Childrens Research Institute
Elective Surgical Procedures, Postoperative Pain
Opioid Free Anesthesia-Analgesia Strategy and Surgical Stress in Elective Open Abdominal Aortic Aneurysm Repair
Open Abdominal Aortic Aneurysm (AAA) repair is a high-risk surgical procedure accompanied by intense endocrine and metabolic responses to surgical stress, with subsequent activation of the inflammatory cascade, cytokine and…
- Conditions
- Elective Surgical Procedures, Postoperative Pain, Anesthesia, Opioid Use
- Trial name
- NCT04894864
- Testing
- Opioid-Based Anesthesia-Analgesia Strategy, Opioid-free Anesthesia-Analgesia Strategy
- Where
- Greece
- Volunteers
- 40 people
- Sponsor
- University of Crete
Condition: Abdominal Bone Flap Cranioplasty; Focus of Study: Perioperative Analgesia
Efficacy Of Scalp Block And Ultrasound Guided TAP Block With Clonidine As Adjuvant To Ropivacaine Versus Intravenous Fentanyl On Intraoperative Hemodynamics And Perioperative Analgesia In Abdominal Bone Flap Cranioplasties
This study assesses efficacy of scalp block and Ultrasound guided transverse abdominis plane (TAP) block with 1µg/kg clonidine as adjuvant to 0.2% ropivacaine versus intravenous fentanyl (0.1µg/kg/hr) on intraoperative…
- Trial name
- NCT03667352
- Testing
- Unilateral Scalp Block, Transversus abdominis plane block, Intravenous Fentanyl
- Where
- India
- Volunteers
- 60 people
- Sponsor
- Dhritiman Chakrabarti
Postoperative Pain, Knee Replacement Arthroplasty
Management of Postoperative Pain After Total Knee Replacement.
The purpose of this study is to compare two methods of postoperative pain management in patients undergoing total knee replacement.
- Trial name
- NCT01163214
- Testing
- Nerve Block, Periarticular Injection
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Mark J. Spangehl, M.D.
Gastric Cancer
Comparison of Ropivacaine-Poloxamer 407 Hydrogel and TAP Block for Postoperative Pain Management in Laparoscopic/Robotic Gastrectomy
This study aims to determine whether Ropivacaine-Poloxamer 407 hydrogel provides non-inferior pain control compared to TAP block for patients undergoing minimally invasive gastrectomy.
- Trial name
- NCT06839716
- Testing
- Arm I (Ropivacaine-Poloxamer 407 hydrogel group), Arm II (TAP block group)
- Where
- South Korea
- Volunteers
- 134 people
- Sponsor
- Gangnam Severance Hospital
Open Thoracotomy
Pharmacokinetic of Thoracic Paravertebral Ropivacaine
The study aims to investigate the pharmacokinetic of ropivacaine in patients undergoing ultrasound guided thoracic paravertebral block (TPVB) both after a single-bolus injection via the thoracic paravertebral catheter given…
- Trial name
- NCT03721406
- Testing
- Ropivacaine
- Where
- 2 sites in Greece
- Volunteers
- 20 people
- Sponsor
- Attikon Hospital
Breast Cancer, Acute Pain
Mid-point Transverse Process to Pleura Block for Breast Cancer Surgery: A Randomized Controlled Trial
This study will compare the analgesic effects of midpoint transverse process to pleura (MTP) block to control as well as thoracic paravertebral block.
- Conditions
- Breast Cancer, Acute Pain, Anesthesia
- Trial name
- NCT03713255
- Testing
- PVB group, MTP block group, Control Group
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- Ottawa Hospital Research Institute
Lower Limb Surgery
Spinal Anaesthesia With Levobupivacaine 0.5% and Ropivacaine 0.75% for Lower Limb Orthopaedic Surgery
The purpose of this study is to compare the effects of two intrathecally administered drugs:0.5% levobupivacaine and0.75%Ropivacaine in spinal anesthesia
- Trial name
- NCT02201784
- Testing
- Levobupivacaine, Ropivacaine
- Where
- India
- Volunteers
- 60 people
- Sponsor
- Aligarh Muslim University
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