Clinical trials: Ropivacaine
Breast Neoplasm Female, Pain, Postoperative
Effectiveness of Ultrasound Guided PECS Block on Opioid Consumption and Patient Satisfaction Through Adequate Pain Control Following Breast Cancer Surgery.
Breast cancer is the most common and leading cause of cancer deaths among females worldwide. Patients undergoing modified radical mastectomy (MRM) are associated with moderate to severe acute postoperative pain and shoulder…
- Conditions
- Breast Neoplasm Female, Pain, Postoperative, Pain, Analgesia
- Trial name
- NCT04343807
- Testing
- PECS Block, Control Group
- Where
- Pakistan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Cesarean Section, Anesthesia, Spinal
Combined Spinal-epidural Anesthesia for Cesarean Section Without Prophylactical Prehydration and Vasopressors
Hypotension is a common complication in pregnant women after spinal anesthesia and related with the dose of local anesthetic. Injecting small dose local anesthetic into subarachnoid space can decrease the incidence of…
- Trial name
- CSEAFCSWPPAV (NCT03497364)
- Testing
- bupivacaine, ropivacaine
- Where
- China
- Volunteers
- 930 people
- Sponsor
- Shenzhen People's Hospital
Pain, Complications
Comparison of Two Kinds of Postoperative Analgesia After Amputation
Pain after amputation is a significant problem among amputees. Phantom limb pain may appear in up to 85% of patients and is usually resistant to a wide variety of treatments.It is believed that regional anesthesia, by preventing…
- Trial name
- NCT02114463
- Testing
- Local analgesic, Intravenous analgesic, ropivacaine
- Where
- China
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Guangzhou General Hospital of Guangzhou Military Command
Chronic Pain
Efficacy of Compound Betamethasone Injection Combined With Ropivacaine in Ultrasound-guided Thoracic Paravertebral Nerve Block for Chronic Post-thoracotomy Pain
Chronic post-thoracotomy pain（CPTP）will not only have a negative impact on patients' physiology and psychology, but also affect postoperative recovery.A number of researches have demonstrated that Injury to the intercostal nerve…
- Trial name
- NCT05175001
- Testing
- Diprospan, Ropivacaine
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Affiliated Hospital of Nantong University
Diabetes Type 2
Evaluation of Block Duration in Type 2 Diabetes Patients
Diabete animal studies demonstrated a longer period recovery after local anesthetic injection (perineural administration). No clinical study demonstrated a prolonged nerve block duration in diabete type 2 patients after…
- Trial name
- Diabeteblock (NCT01704612)
- Testing
- ropivacaine
- Where
- France
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Pierre and Marie Curie University
Injury of Anterior Cruciate Ligament
Comparison of Infiltration Analgesia With Femoral Nerve Block After Hamstrings Anterior Cruciate Ligament Reconstruction
Pain treatment after anterior cruciate ligament reconstruction - Comparison of infiltration analgesia with femoral nerve block after.
- Trial name
- NCT01260363
- Testing
- Femoral nerve block, Local infiltration analgesia
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- University of Aarhus
Cancer Pediatric
Ultrasound-guided Selective Supraclavicular Nerve Block for Postoperative Pain Control in Pediatric Patients.
This prospective randomized controlled trial aims to investigate the effect of ultrasound-guided selective supraclavicular nerve block on pain control after Hickman catheter, chemoport, or Perm cath insertion in children.
- Trial name
- NCT05015907
- Testing
- Ropivacaine, Control (without intervention)
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Seoul National University Hospital
Pain, Postoperative
A Randomized Control Trial Comparing Analgesic Benefits of Ultrasound-guided Single vs Continuous Quadratus Lumborum Blocks (QLB)vs Intrathecal Morphine(ITM) for Post Cesarean Section Pain
the purpose of this study is to compare opioid consumption in morphine equivalents between the groups that received postoperative analgesia with intrathecal morphine versus US guided QL blocks versus US guided QL catheters
- Trial name
- NCT04368364
- Testing
- Intrathecal morphine sulfate (ITM), Bupivacaine hydrochloride, ropivacaine hydrochloride
- Where
- 2 sites in United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Severe Chest Trauma
EffecT of eARly analGesia With Erector Spinae Plane Block to Reduce Ventilation After Severe Chest Trauma
Blunt chest trauma is commonly associated with rib fractures and early pain management is a key goal after chest trauma. In spontaneous breathing patients, pain limits coughing efficiency and secretion clearance, thereby…
- Trial name
- TARGET (NCT05920109)
- Testing
- ESP block
- Where
- 14 sites in France
- Volunteers
- 400 people
- Sponsor
- University Hospital, Grenoble
Regional Anesthesia Morbidity, Postoperative Pain
Local Anesthesia Spread After an Erector Spinae Plane Block.
This a single-center prospective spread-evaluation study where the primary objective is to assess the spread of local anesthesia in an ESPB using magnetic resonance imaging (MRI).
- Trial name
- NCT05012332
- Testing
- Erector Spinae Plane Block
- Where
- Norway
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Ostfold Hospital Trust
Shoulder, Orthopedic Surgery
Ultrasound Guidance for Interscalene Brachial Plexus Block
This study has been designed to assess the possible advantages of using ultrasound imaging to block the brachial plexus (i.e., nerves of the upper limb) in patients undergoing shoulder surgery.
- Conditions
- Shoulder, Orthopedic Surgery, Nerve Block
- Trial name
- NCT00702416
- Testing
- Ultrasound-guided continuous interscalene brachial plexus block, Continuous interscalene brachial plexus block using electrical nerve stimulation, Ropivacaine
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- University of Parma
Surgery, Hand
Analgesic Efficacy of Perineural Dexamethasone During Supraclavicular Block for Hand Surgery
The purpose of this study is to determine whether the addition of dexamethasone prolongs analgesia when added to long-acting local anesthetic during single-injection supraclavicular block for outpatient hand surgery.
- Trial name
- NCT02154048
- Testing
- Ropivacaine, Dexamethasone
- Volunteers
- 5 people
- Sponsor
- Duke University
Hyperalgesia, Pain
Local Anesthetic Infusion and Sternotomy
Cardiac surgery often induces acute postoperative pain and moreover chronic dysesthesia frequently occur long-term after sternotomy.
- Trial name
- CARDIODOLAL (NCT00802048)
- Testing
- Local anesthetic (Ropivacaine), Saline
- Where
- France
- Volunteers
- 21 people
- Sponsor
- University Hospital, Bordeaux
Pain, Postoperative
Erector Spinae Plane Block With Ropivacaine for Major Upper Abdominal Surgery
Prospective, single-centre, randomized, controlled, open-label, evaluator-blinded, superiority trial.
- Trial name
- NCT04702685
- Testing
- Ropivacaine
- Where
- Kazakhstan
- Volunteers
- 50 people
- Sponsor
- Nazarbayev University Medical Center
Spine Surgery, Pain Relief
Erectus Nerve Block for Lumbar Spine Surgery
: Spine surgery induced severe postoperative pain. Several techniques as intravenous multimodal analgesia have been proposed to reduce pain relief and morphine rescue over the first postoperative days.
- Conditions
- Spine Surgery, Pain Relief, Morphine, AdverseEvent
- Trial name
- EFABE (NCT04473508)
- Testing
- Local administration of ropivacaine
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Pain
Comparison of Ultrasound and Nerve Stimulation Technique for Continuous Sciatic Nerve Block
The most useful method to manage pain after major foot and ankle surgery is infusion of local anesthetic with a catheter close to the sciatic nerve in the popliteal space above the knee joint.
- Trial name
- NCT00497276
- Testing
- placement of popliteal catheter
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- University of Aarhus
Breast Cancer Female
Does Type of Anesthesia Influence Inflammation Change After Breast Surgery?
The Neutrophil to Lymphocyte Ratio (NLR) is a frequently used biomarker of the systemic inflammatory response and is considered one of the most sensitive markers of inflammation.
- Trial name
- NCT04172220
- Testing
- Midazolam, PECS, Opioid-free general anesthesia
- Where
- Italy
- Volunteers
- 68 people
- Sponsor
- Centro di Riferimento Oncologico - Aviano
Colorectal Disorders
Intraperitoneal Local Anaesthetic in Bowel Surgery
This study will evaluate the addition of a local anaesthetic infusion into the abdomen to patient controlled analgesia in the management of postoperative pain and recovery after bowel surgery.
- Trial name
- NCT02449720
- Testing
- Ropivacaine, 0.9% Saline
- Where
- Australia
- Volunteers
- 86 people
- Sponsor
- Royal Adelaide Hospital
Surgery
Ultrasound-guided Thoracic Paravertebral Block Using Ropivacaine With/Without Dexamethasone in Elective Thoracotomy
The procedures of thoracotomy are among the most painful operations. In addition to post-thoracotomy pain, the outcomes of surgery are affected adversely by postoperative discomfort.
- Trial name
- NCT02871193
- Testing
- Ropivacaine, Dexamethasone, saline
- Where
- China
- Volunteers
- 68 people
- Sponsor
- The First Affiliated Hospital of Anhui Medical University
Video-Assisted Thoracic Surgery, Video-Assisted Thoracoscopic Surgery
Optimal Timing of Intercostal Nerve Blocks During Video-Assisted Thoracic Surgeries
Intercostal nerve block, performed under the guidance of videoscope, is a part of standard anesthesia procedures for patients receiving Video-Assisted Thoracic Surgeries.
- Trial name
- NCT02980835
- Testing
- Normal Saline, Ropivacaine, Epinephrine
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University at Buffalo
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