Clinical trials: Ropivacaine
Acute Achilles Tendon Rupture
Popliteal Nerve Block for Acute Achilles Tendon Rupture Repair Surgery
Achilles tendon rupture is common, yet the value of popliteal nerve block for postoperative pain control during surgical repair remains uncertain.
- Trial name
- NCT06886815
- Testing
- Popliteal Nerve Block
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Women's College Hospital
Pharmacological Action
Comparison of Epidural Labor Analgesia With Dexmedetomidine or Sufentanil
The participants: 1800 full-term primiparas will be selected with ASA I-Ⅱgrade, 20 to 35 years old and weighing 55 to 90 kg in the investigator's hospital from may 2018 to December 2018.
- Trial name
- NCT03622047
- Testing
- Dexmedetomidine ropivacaine, No analgesia labor
- Where
- China
- Volunteers
- 1,800 people
- Sponsor
- Fudan University
Postoperative Pain
Effect of Quadratus Lumborum Block With Compound Lidocaine and Esketamine on Pain After Colorectal Surgery
Purpose: To explore effects of ultrasound-guided quadratus lumborum block with compound lidocaine and esketamine on postoperative pain after colorectal surgery.
- Trial name
- NCT05964985
- Testing
- Normal saline, Ropivacaine, Compound lidocaine
- Volunteers
- 160 people
- Sponsor
- Tianjin Medical University General Hospital
Nerve Block, Surgical Conditions
Effect of the Sheath of Rectus Abdominis Block Combined With the Transverse Plane
The situation of demand for surgical conditions is quite high when lymph node resection involved in the surgery type, especially abdominal aortic lymph node dissection, and commonly, the surgeons complained about the interference…
- Trial name
- NCT04850404
- Testing
- abdominal nerve block
- Volunteers
- 42 people
- Sponsor
- Tongji Hospital
Amputation, Phantom Limb
Naval Medical Center San Diego (NMCSD) - Ambulatory Continuous Peripheral Nerve Blocks for Treatment of Post-Amputation Phantom Limb and Stump Pain
The purpose of this research study is to determine if putting local anesthetic-or numbing medication-through one or two tiny tube(s) placed next to the nerves that go to an amputated limb will decrease phantom limb and/or stump…
- Conditions
- Amputation, Phantom Limb, Stump Pain
- Trial name
- NCT00768248
- Testing
- perineural ropivacaine
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of California, San Diego
PTSD
Efficacy of Cervical Sympathetic Blocks for PTSD
Millions of people suffer from anxiety disorders, including posttraumatic stress disorder (PTSD)-a condition that can profoundly disrupt daily life.
- Trial name
- NCT07087015
- Testing
- Cervical sympathetic nerve block, Ropivacaine, Normal Saline
- Volunteers
- 20 people
- Sponsor
- Stanford University
Interscalene Block, Shoulder Arthroscopy
Prolongation of Pain Free Time by the Use of Dexamethasone in Peripheral Nerve Blockade
The main aim of the study is to investigate the proven effect of dexamethsone on the duration of the interscalene block. The investigators try to define optimal dose and volume for ropivacaine, when used together with…
- Conditions
- Interscalene Block, Shoulder Arthroscopy, Dexamethasone, Low Volume Regional Anesthesia
- Trial name
- NCT02178449
- Testing
- Dexamethasone acetate, Ropivacaine
- Where
- 2 sites in Austria
- Volunteers
- 109 people
- Sponsor
- Landesklinikum Sankt Polten
Hip Fracture
Analgesia for Positioning Hip Fracture Patients for Spinal Anesthesia
The purpose of this study is to compare two analgesic methods performed preoperatively to assist positioning patients for performance of spinal anesthesia, namely fascia iliaca blockade and intravenous fentanyl.
- Trial name
- NCT02037633
- Testing
- Fentanyl, Fascia iliaca compartment block, ropivacaine
- Where
- Greece
- Volunteers
- 41 people
- Sponsor
- Asklepieion Voulas General Hospital
Analgesia, Epidural, Instrumental Delivery
The Randomised Epidural Analgesia in Term Delivering Women Trial (TREAT)
The objective of the study: to assess the impact of a proactive policy of offering EA at the start of labour as compared to a restrictive policy or care as usual.
- Conditions
- Analgesia, Epidural, Instrumental Delivery, Maternal Outcome, Neonatal Outcome
- Trial name
- TREAT (NCT01261689)
- Testing
- Ropivacaine/ Sufentanil according to local hospital protocol, Care-as usual pain treatment
- Where
- 2 sites in Netherlands
- Volunteers
- 488 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Tendon Injury - Hand
Wide-Awake Local Anesthesia vs. Regional/General Anesthesia for Flexor Tendon Repair
Wide-awake hand surgery with local anesthetic, no tourniquet and no sedation (WALANT) is increasingly utilized. Conventional anesthesia for hand surgery involves a patient with a block, unable to perform motor function in the…
- Trial name
- NCT03135340
- Testing
- WALANT, General/regional anesthesia, WALANT Injection
- Volunteers
- 88 people
- Sponsor
- University of Western Ontario, Canada
Phantom Limb Pain
Treating Phantom Limb Pain Using Continuous Peripheral Nerve Blocks: A Department of Defense Funded Multicenter Study
When a limb is traumatically severed, pain perceived in the part of the body that no longer exists often develops. This is called "phantom limb" pain, and is different from "stump" pain, which is pain within the part of the limb…
- Trial name
- DoD-PLP-Tx (NCT01824082)
- Testing
- Perineural infusion [continuous peripheral nerve block(s)]
- Where
- 4 sites in United States
- Volunteers
- 144 people
- Sponsor
- University of California, San Diego
Craniotomy
Scalp Block in Elective Craniotomy for Tumor Dissection Trial
This study was designed to evaluate the effect of scalp block combined with general anesthesia on the intraoperative consumption of fentanyl and time of extubation of patients undergoing elective craniotomy.
- Trial name
- NCT03776617
- Testing
- scalp block
- Where
- Greece
- Volunteers
- 120 people
- Sponsor
- George Papanicolaou Hospital
Pain, Postoperative
Blood Ropivacaine Concentrations Following Chest Wall Nerve Block Continuous Infusion
The main objective of this proposed investigation is to evaluate blood ropivacaine concentrations in infants and toddlers following the initiation of, and over the course of, continuous paravertebral nerve blockade using…
- Trial name
- NCT02860091
- Testing
- Ropivacaine infusion
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Boston Children's Hospital
General Anesthesia, Propofol Target-controlled Infusion
Effects of Epidural Local Anesthetics on Propofol Induction
The investigators designed a prospective, randomized, placebo-controlled study to determine whether thoracic epidural anesthesia(TEA) with different local anesthetics has different influences on the propofol dose during induction.
- Conditions
- General Anesthesia, Propofol Target-controlled Infusion, Thoracic Epidural Anesthesia
- Trial name
- NCT02000973
- Testing
- Lidocaine, Bupivacaine, Ropivacaine
- Volunteers
- 80 people
- Sponsor
- First Hospital of China Medical University
Distribution of Ropivacaine in Erector Spinae Plane Block
Distribution, Pharmacokinetics and Extent of Sensory Blockade in ESP Blocks
The primary objectives of this study are to define the extent of dermatomal anesthesia and anatomical spread of injectate (as defined by MRI imaging) that is provided by an ESP block at the T5 level, using twenty milliliters of…
- Trial name
- NCT03476642
- Testing
- Ropivacaine, Epinephrine
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Local Anesthesia Adjuvants, Upper Extremity Fracture
Effect of Dexmedetomidine As Adjuvant to Ropivacaine for Brachial Plexus Block
Brachial plexus block is used for upper limb surgery. Local anesthesia alone for brachial plexus block provides good operative conditions, but have short duration of postoperative analgesia.
- Conditions
- Local Anesthesia Adjuvants, Upper Extremity Fracture, Brachial Plexus Block
- Trial name
- NCT05767827
- Testing
- ropivacaine, lidocaine with adrenaline, Dexmedetomidine, ropivacaine, lidocaine with adrenaline
- Where
- Nepal
- Volunteers
- 40 people
- Sponsor
- Nepal Medical College and Teaching Hospital
Laparoscopic Gastrectomy
The MEC90 of Epidural Ropivacaine Blunting Hemodynamic Changes to Pneumoperitoneum
Investigators want to find the concentration of epidural ropivacaine, which can block hemodynamic changes in the onset of pneumoperitoneum in the laparoscopic gastrectomy.
- Trial name
- NCT04247373
- Testing
- Ropivacaine
- Volunteers
- 50 people
- Sponsor
- Keimyung University Dongsan Medical Center
Rhizarthrosis, Metabolic Disease
Saline Lavage X Saline Lavage and Osteonil® Mini in Rizarthritis
Although a common problem, hand osteoarthritis (HOA) is less studied than knee and hip. In the age group of 71-100 years, the prevalence of symptomatic HOA reaches 26% of women and 13% of men.
- Trial name
- NCT03089723
- Testing
- Visual Analog Scale (VAS), Range of Motion (ROM), Palmar grip strength
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- University of Sao Paulo General Hospital
Inguinal Hernia Repair
A Trial of HR18034 in Inguinal Hernia Repair
Phase I, randomized, double-blind, comparator-controlled study to assess the safety, PK, and efficacy of single postsurgical application of HR18034 compared with Naropin®
- Trial name
- NCT04551924
- Testing
- HR18034, Naropin
- Where
- China
- Volunteers
- 64 people
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Pain, Postoperative
Does the Preoperative Midazolam Dose Affect Postoperative Pain?
To investigate whether midazolam has any effect on postoperative pain in outpatient surgery, the investigators will assess the impact of different midazolam doses on pain scores 24h, 7 days and 3 months after ambulatory surgery.
- Trial name
- NCT03534895
- Testing
- Midazolam Injectable Solution, Normal saline, Spinal anesthesia
- Where
- 2 sites in Portugal
- Volunteers
- 168 people
- Sponsor
- Universidade do Porto
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