Clinical trials: Rosuvastatin
Oxidative Stress, Diabetic Polyneuropathy
Statins for Oxidative Stress and Mitochondrial Function in Diabetic Polyneuropathy
Aims: To evaluate the effect of ezetimibe/simvastatin and rosuvastatin on oxidative stress and mitochondrial function in patients with DPN.
- Trial name
- NCT02129231
- Testing
- calcined magnesia, Ezetimibe/simvastatin, Rosuvastatin
- Where
- Mexico
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- University of Guadalajara
Hypertension, Hyperlipidemia
CKD-346 DDI Study(Telmisartan/S-Amlodipine, Rosuvastatin)
The purpose of this study is to evaluate the drug-drug interaction of CKD-346(Telmisartan/S-Amlodipine, Rosuvastatin)
- Trial name
- NCT02047175
- Testing
- Telmisartan/S-Amlodipine, Rosuvastatin, Telmisartan/S-Amlodipine + Rosuvastatin
- Where
- South Korea
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Chong Kun Dang Pharmaceutical
Elevated High-sensitivity C-Reactive Protein (hsCRP)
JUPITER - Crestor 20mg Versus Placebo in Prevention of Cardiovascular (CV) Events
The purpose of this study is to determine the safety and effectiveness of long-term therapy with rosuvastatin compared with a placebo, and to evaluate whether treatment with rosuvastatin might be effective in reducing the risk of…
- Trial name
- NCT00239681
- Testing
- Rosuvastatin
- Where
- 856 sites in United States, Argentina and 25 more
- Volunteers
- 17,802 people
- Sponsor
- AstraZeneca
Hypertension, Hyperlipidemia
Efficacy and Safety of Telmisartan/Rosuvastatin Co-administration in Hypertensive Patients With Hyperlipidemia
To identify efficacy and safety of Telmisartan/Rosuvastatin co-administration in hyperlipidemia control in hypertensive patients with hyperlipidemia compared to each monotherapy.
- Trial name
- NCT02087540
- Testing
- Telmisartan 80mg, Rosuvastatin 20mg, Rosuvastatin 10mg
- Where
- South Korea
- Volunteers
- 310 people
- Sponsor
- IlDong Pharmaceutical Co Ltd
Diabetes Mellitus
Comparison of PK After Administration of HCP1201 and Co-administration of Metformin SR 500mg and Rosuvastatin 10mg
To compare the pharmacokinetic characteristics between HCP1201 tablet 500/10 mg and co-administration of metformin 500 mg plus rosuvastatin 10 mg under fasted and fed state, respectively.
- Trial name
- NCT02011633
- Testing
- HCP1201 500/10mg, Metformin SR 500mg, Rosuvastatin 10mg
- Where
- South Korea
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Hanmi Pharmaceutical Company Limited
Diabetes Mellitus
Comparison of PK After Administration of HCP1201 and Co-administration of Metformin SR 750mg and Rosuvastatin 10mg
To compare the pharmacokinetic characteristics between HCP1201 tablet 750/10 mg and co-administration of metformin 750 mg plus rosuvastatin 10 mg under fed state condition.
- Trial name
- NCT02026817
- Testing
- HCP1201 750/10mg, Metformin SR 750mg, Rosuvastatin 10mg
- Where
- South Korea
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Hanmi Pharmaceutical Company Limited
Healthy
A Pilot Study to Evaluate the Pharmacokinetics of Omega-3 Between Rosuvastatin and Omega-3 Coadministration and HCP1007
The purpose of this study is to evaluate the pharmacokinetics of omega-3 between rosuvastatin and omega-3 coadministration and HCP1007 in healthy male volunteers.
- Trial name
- NCT01929070
- Testing
- HCP1007, Omarco and Crestor
- Where
- South Korea
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Hanmi Pharmaceutical Company Limited
Platelet Dysfunction
Evaluation of Platelet Function After Statin Loading Dose in Patients Before Percutaneous Coronary Intervention
The purpose of this study is to evaluate the effect of a loading dose of two different statins on platelet reactivity (atorvastatin, metabolized by CYP3A4, and rosuvastatin, which is rather independent of this enzyme)in patients…
- Trial name
- STATIPLAT (NCT01526460)
- Testing
- Atorvastatin, Rosuvastatin
- Where
- Italy
- Volunteers
- 146 people
- Sponsor
- IRCCS San Raffaele
Healthy
Pharmacokinetic Drug Interaction Between Candesartan and Rosuvastatin
The objective of this study is to compare pharmacokinetics after single oral administration of candesartan and rosuvastatin each separately versus coadministration of candesartan and rosuvastatin in healthy male volunteers.
- Trial name
- NCT02079506
- Testing
- Candesartan, Rosuvastatin
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Alvogen Korea
Dilated Cardiomyopathy
Effect of Rosuvastatin on Left Ventricular Remodeling
The purpose of this study is to examine the the effect of the HMG-CoA reductase inhibitor Rosuvastatin on left ventricular remodeling in patients with dilated cardiomyopathy.
- Trial name
- NCT00505154
- Testing
- Rosuvastatin
- Where
- Norway
- Volunteers
- 75 people
- Sponsor
- Oslo University Hospital
Patients With Coronary Artery Disease Scheduled for by Pass Surgery
Atrial Fibrillation and By-pass Surgery
The aim of the study is to evaluate whether combined therapy with beta-blocker, amiodarone and statine is better than beta-blocker alone for the prevention of atrial fibrillation after coronary by-pass surgery.
- Trial name
- NCT01955759
- Testing
- Amiodarone tab 200 mg x 3, rosuvastatin 20 mg tab x1, beta blockers Bisoprolol in adjusted dose
- Where
- Bosnia and Herzegovina
- Volunteers
- 260 people
- Sponsor
- Heart Center BH Tuzla
Type IIa and IIb Hypercholesterolaemia
Evaluation of the Efficacy and Safety of Rosuvastatin 5 mg Versus Pravastatin 40 mg and Atorvastatin 10 mg in Type IIa and IIb Hypercholesterolaemic Patients
The purpose of this study is to evaluate the efficacy and safety of Rosuvastatin 5 mg as an hypercholesterolemia treatment comparatively at 2 other statins: Pravastatin 40 mg and Atorvastatin 10 mg.
- Trial name
- CAP-Chol (NCT00631189)
- Testing
- Rosuvastatin, Pravastatin, Atorvastatin
- Where
- 170 sites in France
- Volunteers
- 668 people
- Sponsor
- AstraZeneca
Healthy Volunteer
A Randomized, Open-label, Multiple-dose, Crossover Study to Investigate the Pharmacokinetic Drug Interaction Between Rosuvastatin and Telmisartan in Healthy Volunteer
This clinical trial is designed to compare the pharmacokinetic characteristics of combination and separate administration of Crestor(Rosuvastatin) and Micardis(Telmisartan).
- Trial name
- YH16410 DDI (NCT01992601)
- Testing
- Crestor 20mg(Rosuvastatin 20mg), Micardis 80mg(Telmisartan 80mg)
- Where
- South Korea
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Yuhan Corporation
Diabetes
The Statins on Glucose Homeostasis in Subjects With Impaired Fasting Glucose
Evaluate the effects of rosuvastatin (maybe the highest diabetogenic) and pravastatin (seems to be protective) on the glucose homeostasis and other biomarkers in subjects with impaired fasting glucose.
- Trial name
- NCT01816997
- Testing
- Pravastatin, Rosuvastatin, Control
- Where
- Taiwan
- Volunteers
- 160 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Hypercholesterolemia
A Study to Evaluate the Efficacy and Safety of Rosuvastatin in Hypercholesterolemia.
The objective of this trial is to assess the efficacy of reducing plasma low-density lipoprotein(LDL) cholesterol and safety in two different brand drugs, Roty F.C. Tablets 10mg and Crestor 10mg F.C.
- Trial name
- NCT01982461
- Testing
- Rosuvastatin, Crestor®
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- Pin Siang Medical Biotechnology Co., Ltd.
Stroke, Transient Ischemic Attack
Rosuvastatin in African Americans With Cerebrovascular Disease
This study will assess the rate at which rosuvastatin will achieve LDL targets in African American patients with previous history of stroke or TIA.
- Trial name
- RIAA (NCT01975194)
- Testing
- Rosuvastatin
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Wayne State University
Dyslipidemia & Hypertension
PK Study of Telmisartan/Rosuvastatin FDC Compared to Combination of Telmisartan and Rosuvastatin
This is a 2 by 2 cross-over study to evaluate pharmacokinetics of telmisartan and rosuvastatin FDC compared to reference telmisartan and rosuvastatin coadministered in two groups enrolling healthy adult male and female subjects…
- Trial name
- NCT01975961
- Testing
- Crestor 20mg(Rosuvastatin 20mg), Micardis 80mg(Telmisartan 80mg) , FDC
- Where
- South Korea
- Volunteers
- 185 people, healthy volunteers welcome
- Sponsor
- Yuhan Corporation
A Total of 234 Patients With Acute Coronary Syndrome Who Will Undergo OPCAB.
Impact of High-dose Pretreatment of Rosuvastatin in Patients With Acute Coronary Syndrome Following Off-pump Coronary Artery Bypass: Results From the HIROP-ACS (HIgh-dose Pretreatment of Rosuvastatin During Off-Pump Coronary Bypass in Acute Coronary Syndrome) Study
Periprocedural treatment with high-dose statins is known to have cardioprotective and pleiotropic effects, such as anti-thrombotic and anti-inflammatory actions.
- Trial name
- NCT01971606
- Testing
- Rosuvastatin
- Where
- South Korea
- Volunteers
- 234 people
- Sponsor
- Yonsei University
Coronary Artery Disease
Randomized Trial of Creatine-kinase Leak After Rosuvastatin At the Time of Percutaneous Coronary Intervention
Patients with stable coronary disease when undergoing percutaneous coronary intervention may present periprocedural myocardial infarction defined at present as a creatine kinase-myocardial isoenzyme (CK-MB) elevation 3 times…
- Trial name
- CLEAR-PCI (NCT01968577)
- Testing
- Rosuvastatin
- Where
- Brazil
- Volunteers
- 528 people
- Sponsor
- Kleber Bomfim Araujo Martins
Hypertension
To Evaluate the Pharmacokinetic Interactions and Safety Between Fimasartan and Rosuvastatin
A phase Ⅰ study to evaluate the pharmacokinetic interactions and safety between fimasartan and rosuvastatin in healthy male volunteers.
- Trial name
- NCT01921946
- Testing
- Fimasartan, Rosuvastatin
- Where
- South Korea
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Boryung Pharmaceutical Co., Ltd