Clinical trials: Rosuvastatin
Ischemic Stroke, Large-Artery Atherosclerosis (Embolus/Thrombosis)
Study of Predictive Factors Related to Prognosis of Patients With Ischemic Stroke Due to Large-artery Atherosclerosis
This is a single-center prospective cohort study of predictive factors related to prognosis of ischemic stroke due to large-artery atherosclerosis.
- Trial name
- NCT04847752
- Testing
- carotid artery stenting, carotid endarterectomy, Aspirin
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Tongji Hospital
Hypercholesterolemia, Atherosclerosis
Switching to Rosuvastatin Versus Adding Ezetimibe to Atorvastatin Versus Doubling the Dose of Atorvastatin in Patients With Hypercholesterolemia and Risk Factors (P03708)
This study assesses whether adding ezetimibe 10 mg/d to ongoing treatment with atorvastatin 10 mg/d is more effective than switching the subject to treatment with rosuvastatin 10 mg/d or doubling the dose of atorvastatin to 20…
- Conditions
- Hypercholesterolemia, Atherosclerosis, Coronary Artery Disease
- Trial name
- NCT00651378
- Testing
- Rosuvastatin, Ezetimibe + Atorvastatin, Double Atorvastatin
- Volunteers
- 87 people
- Sponsor
- Organon and Co
Drug Interaction Potentiation
Drug-Drug Interaction Study of Vadadustat With Rosuvastatin, Sulfasalazine, Pravastatin, Atorvastatin and Simvastatin
This is a Phase 1, three-part, open-label study to evaluate vadadustat as a perpetrator in drug-drug interactions with rosuvastatin, sulfasalazine, pravastatin, atorvastatin and simvastatin in healthy male and female subjects.
- Trial name
- NCT03801733
- Testing
- Vadadustat, Simvastatin, Rosuvastatin
- Where
- Canada
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Akebia Therapeutics
Venous Thromboembolism
StAtins for Venous Event Reduction in Patients With Venous Thromboembolism Pilot Study
The SAVER pilot is a randomized, open-label pilot study to determine the feasibility of recruitment. In addition to feasibility data, the investigators will carefully collect clinical data to determine if rosuvastatin can reduce…
- Trial name
- SAVER (NCT02679664)
- Testing
- Rosuvastatin
- Where
- 6 sites in Canada, Norway
- Volunteers
- 312 people
- Sponsor
- Ottawa Hospital Research Institute
Type 2 Diabetes, Dyslipidemia
Gemigliptin-Rosuvastatin Fix-dose Combination Phase 3(BALANCE)
To evaluate the efficacy and safety of the fix-dose combination therapy with Gemigliptin 50mg and Rosuvastatin 20mg with type 2 diabetes and dyslipidemia
- Trial name
- NCT02126358
- Testing
- Gemigliptin and/or Rosuvastatin
- Where
- South Korea
- Volunteers
- 290 people
- Sponsor
- LG Life Sciences
Healthy Participants
A Study to Investigate the Effect of AZD5004 on Rosuvastatin, Atorvastatin, Simvastatin, Repaglinide and the Effect of Erythromycin on AZD5004 in Healthy Participants
This study will assess the effect of AZD5004 on Rosuvastatin, Atorvastatin, Simvastatin, Repaglinide and the effect of Erythromycin on AZD5004 in healthy adult male and female participants.
- Trial name
- NCT06948747
- Testing
- AZD5004, Rosuvastatin, Erythromycin
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Atherosclerotic Cardiovascular Disease
Effects of Ezetimibe Combination Therapy for Patients With Atherosclerotic Cardiovascular Disease; Randomized Comparison of LDL-cholesterol Targeting <70 Versus <55mg/dL; Ez-PAVE Trial
Although the clinical efficacy of LDL-cholesterol lowering therapy has been proven with strong evidences and emphasized, there are also growing concerns that intensive lipid-lowering therapy would be related to increased risk of…
- Trial name
- NCT04626973
- Testing
- Ezetimibe/Statin Combination therarpy (ezetimibe plus rosuvastatin), Statin monotherapy (rosuvastatin or atorvastatin)
- Where
- South Korea
- Volunteers
- 3,048 people
- Sponsor
- Yonsei University
Lactating Women on Select DOI, Breastfed Infants of Mothers on Select DOI
Pharmacokinetics and Safety of Commonly Used Drugs in Lactating Women and Breastfed Infants
Over half of women in the US who are breastfeeding their infants take prescription drugs. You are being asked to participate in this study because you are breastfeeding your infant and are currently taking, as part of your…
- Trial name
- NCT03511118
- Testing
- Tranexamic acid (TXA), labetalol, metformin
- Where
- 22 sites in United States, Canada
- Volunteers
- 1,600 people
- Sponsor
- Duke University
Hypercholesterolemia
A Study to Evaluate the Efficacy and Safety of Rosuvastatin in Hypercholesterolemia.
The objective of this trial is to assess the efficacy of reducing plasma low-density lipoprotein(LDL) cholesterol and safety in two different brand drugs, Roty F.C. Tablets 10mg and Crestor 10mg F.C.
- Trial name
- NCT01982461
- Testing
- Rosuvastatin, Crestor®
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- Pin Siang Medical Biotechnology Co., Ltd.
Acute Aortic Syndrome, Aortopathy
Protective Effect of Statin Against Negative Cardiovascular Remodeling and Organ Dysfunction After Acute Aortic Syndrome Surgery (PANDA III)
Acute Aortic Syndrome (AAS)/Aortic Aneurysm is a common feature of aortic wall events, including aortic dissection, intramural hematoma, aortic ulceration and aortic trauma, and occurs in up to 35 cases per 100,000 cases per year…
- Trial name
- PANDA (NCT04699279)
- Testing
- Rosuvastatin 10mg
- Where
- 5 sites in China
- Volunteers
- 300 people
- Sponsor
- Nanjing Medical University
Healthy Subjects
A Phase I Study of the Interaction of D-2570 With Other Drugs in Healthy Adults
The primary purpose of this study is to characterize the drug-drug interaction profiles of D-2570 with midazolam, digoxin, rosuvastatin, metformin, itraconazole, rifampicin, and omeprazole.
- Trial name
- NCT07875842
- Testing
- Itraconazole, Rifampicin, Omeprazole
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- InventisBio Co., Ltd
Enhanced External Counterpulsation (EECP), Acute Myocardial Infarction (AMI)
Effect of Enhanced External Counterpulsation
This study evaluated the efficacy and safety of enhanced extracorporeal counterpulsation for cardiac rehabilitation in patients after DCB for acute myocardial infarction.
- Conditions
- Enhanced External Counterpulsation (EECP), Acute Myocardial Infarction (AMI), Drug-coated Balloon, Cardiac Rehabilitation
- Trial name
- EECP (NCT06877390)
- Testing
- conventional drug and exercise rehabilitation, EECP-based rehabilitation regimen
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Chongming Hospital Affiliated to Shanghai University of Health & Medicine Sciences
Dyslipidemia
Efficiency of Rosuvastatin Versus the Fixed Combination of Ezetimibe/Simvastatin in Outpatients
The aim of this study is to evaluate the effectiveness of Rosuvastatin versus Ezetimibe/Simvastatin in dyslipidemic patients treated for at least 8 weeks.
- Trial name
- NCT01164397
- Where
- 9 sites in Mexico
- Volunteers
- 268 people
- Sponsor
- AstraZeneca
Dyslipidemia
Efficacy and Safety of PRC-4016 in Subjects With Mixed Dyslipidemia
The objective of this study is To evaluate the efficacy of PRC-4016 by assessment of the percentage change in blood lipids and lipoprotein parameter from baseline after 12 weeks of treatment To evaluate the safety of PRC-4016 as…
- Trial name
- NCT01972178
- Testing
- PRC-4016, Statins
- Where
- 29 sites in United States
- Volunteers
- 113 people
- Sponsor
- Pronova BioPharma
Healthy Volunteer
An Open-label DDI Study to Investigate the Effect of Rilzabrutinib on P-gp, BCRP, OATP1B1 and OATP1B3 Inhibition
The study is a single-center, Phase-1, open-label, one-sequence, two-treatment period, cross-over, DDI study designed to investigate the effects of rilzabrutinib on the PK of digoxin (as P-gp substrate) and of rosuvastatin (as…
- Trial name
- NCT07855250
- Testing
- Rilzabrutinib, Rosuvastatin, Digoxin
- Where
- Canada
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Sanofi
Healthy Male
A Study to Evaluate the Effects of D-1553 on PK of Midazolam, Caffeine, Rosuvastatin, Furosemide, Digoxin, and Itraconazole or Omeprazole on PK of D-1553
This is a phase I study to evaluate drug-drug interactions (DDIs) of D-1553 as a perpetrator combined with midazolam (CYP3A4 substrate), caffeine (CYP1A2 substrate), rosuvastatin (OATP1B1/OATP1B3 substrate), furosemide…
- Trial name
- NCT06105255
- Testing
- D-1553
- Where
- China
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- InventisBio Co., Ltd
Healthy Volunteers, Pharmacokinetics
Drug-drug Interaction Study Using Rosuvastatin as a Breast Cancer Resistant Protein (Efflux Transporter), Organic Anion-transporting Polypeptide (OATP)1B1, and OATP1B3 (Uptake Transporters) Probe Substrate
Evaluation of the potential perpetrator effect of BAY1841788 (ODM-201) on rosuvastatin pharmacokinetics. PK of BAY1841788 (ODM-201) after single and repeated administration in male and female subjects.
- Conditions
- Healthy Volunteers, Pharmacokinetics, Drug Interaction
- Trial name
- NCT02671097
- Testing
- Rosuvastatin, BAY1841788 (ODM-201)
- Where
- Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bayer
Hypertension, Dyslipidemias
Reduction Efficacy of OLOMAX for Blood Pressure and Low-density Lipoprotein Cholesterol in Hypertensive Patients With Dyslipidemia
This study is a large-scale, prospective, multi-center, and non-interventional observation study to observe blood pressure and blood lipid changes and safety during administration of olomax tablets for 24 weeks in hypertensive…
- Trial name
- NCT05660135
- Testing
- Olmesartan Medoxomil/ Amlodipine Besylate/ Rosuvastatin Ca
- Where
- South Korea
- Volunteers
- 4,000 people
- Sponsor
- Daewoong Pharmaceutical Co. LTD.
Hyperlipidemias
A Phase 1 Study to Evaluate the Safety and Pharmacokinetics of Ezerosu Tab
A Phase 1 Study to Evaluate the Safety and Pharmacokinetics of Ezerosu Tab
- Trial name
- NCT06225635
- Testing
- Ezerosu(monolayer tablet), Ezerosu(double layer tablet)
- Where
- South Korea
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Shin Poong Pharmaceutical Co. Ltd.
Hypertension With Hyperlipidemia
Efficacy/Safety of Telmisartan/Amlodipine/Rosuvastatin in Hypertensive Patients With Hyperlipidemia
A Randomized, Double-blind, Multi-center Phase III Clinical Trial to Evaluate the Efficacy and Safety of Telmisartan/Amlodipine and Rosuvastatin Co-administration in Hypertensive Patients with Hyperlipidemia
- Trial name
- NCT03566316
- Testing
- Telmisartan/Amlodipine, Rosuvastatin, Telmisartan
- Where
- South Korea
- Volunteers
- 134 people
- Sponsor
- IlDong Pharmaceutical Co Ltd