Clinical trials: Rosuvastatin
Metastatic Colorectal Cancer
Fruquintinib DDI Study With P-gp and BCRP Substrates
Fruquintinib DDI Study with P-gp and BCRP Substrates
- Trial name
- NCT05368805
- Testing
- Fruquintinib, Dabigatran Etexilate, Rosuvastatin
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Hutchmed
Stroke, Transient Ischemic Attack
Rosuvastatin in African Americans With Cerebrovascular Disease
This study will assess the rate at which rosuvastatin will achieve LDL targets in African American patients with previous history of stroke or TIA.
- Trial name
- RIAA (NCT01975194)
- Testing
- Rosuvastatin
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Wayne State University
Chronic Periodontitis
Efficacy of Locally Delivred 1.2% Rosuvastatin Gel in Chronic Periodontitis
BACKGROUND: Chronic periodontitis (CP) is an inflammatory condition affecting tooth supporting tissues and alveolar bone that surround the tooth leading to formation of deepend gingival sulcus that is highly prone to pathologic…
- Trial name
- NCT02283515
- Testing
- Rosuvastatin
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Government Dental College and Research Institute, Bangalore
Parkinson's Disease
A Drug Interaction Study of KW-6356 With Midazolam, Caffeine, or Rosuvastatin
The purpose of this study is to evaluate the influence of repeated oral doses of KW-6356 on the pharmacokinetics of index substrates for CYP3A4/5, CYP1A2 and BCRP.
- Trial name
- NCT03970798
- Testing
- Midazolam, Caffeine, Rosuvastatin
- Where
- Japan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Kyowa Kirin Co., Ltd.
Chronic Periodontitis, Type2 Diabetes
1.2% Rosuvastatin Subgingivally Delivered In Chronic Periodontitis With Type 2 Diabetes Mellitus
The purpose of the present study was to evaluate the effects of subgingival delivery of 1.2% Rosuvastatin (RSV) gel as an adjunct to scaling and root planing in chronic periodontitis (CP) with Type 2 diabetes mellitus patients.
- Trial name
- NCT02985099
- Testing
- SRP plus Rosuvastatin gel
- Where
- India
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Government Dental College and Research Institute, Bangalore
Coronary Artery Disease
Effects of Inclisiran Combined With Statins on the Morphology of Coronary Vulnerable Plaques
Effects of inclisiran + statins vs. statins on the morphology and vascular function of coronary vulnerable plaques, in order to provide a better treatment and more detailed imaging basis for the treatment of coronary vulnerable…
- Trial name
- EItoCVP (NCT06338293)
- Testing
- Inclisiran sodium, Rosuvastatin
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Hypercholesterolemia, Dyslipidaemia
Treatment of Hypercholesterolaemia in Hispanic Subjects (STARSHIP)
The purpose of this study is to compare the effect of 6 weeks of treatment with Rosuvastatin with 6 weeks of treatment with Atorvastatin in Hispanic subjects with hypercholesterolemia
- Trial name
- STARSHIP (NCT00653965)
- Testing
- Rosuvastatin, Atorvastatin
- Volunteers
- 3,000 people
- Sponsor
- AstraZeneca
Dyslipidemia
Clinical Trial to Evaluate the Efficacy and Safety of Suvaro®OD Tablet in Patients With Dyslipidemia
The aim of study is to evaluate the efficacy and safety of the new generic formulation (rosuvastatin orally disintegrating tablet (SUVARO®ODT) in patients with dyslipidemia.
- Trial name
- NCT06153433
- Testing
- Rosuvastatin Immediate-Release Tablet (IRT) 10mg, Rosuvastatin orally disintegrating tablet (SUVARO®ODT) 10mg
- Where
- South Korea
- Volunteers
- 112 people
- Sponsor
- Yonsei University
Lactating Women on Select DOI, Breastfed Infants of Mothers on Select DOI
Pharmacokinetics and Safety of Commonly Used Drugs in Lactating Women and Breastfed Infants
Over half of women in the US who are breastfeeding their infants take prescription drugs. You are being asked to participate in this study because you are breastfeeding your infant and are currently taking, as part of your…
- Trial name
- NCT03511118
- Testing
- Tranexamic acid (TXA), labetalol, metformin
- Where
- 22 sites in United States, Canada
- Volunteers
- 1,600 people
- Sponsor
- Duke University
HIV, Hypercholesterolaemia
Treatment With Rosuvastatin Versus Switching PI (Protease Inhibitor) in Patients HIV With High Cholesterol Levels
To compare the effect of rosuvastatin to protease inhibitor switching on fasting total cholesterol over 12 weeks.
- Trial name
- SOS (NCT01935674)
- Testing
- Switch ritonavir-boosted PI, Continue Ritonavir-boosted PI+Rosuvastatin
- Where
- Spain
- Volunteers
- 43 people
- Sponsor
- Juan A. Arnaiz
Prostate Cancer, Cardiovascular Disease
A Study for Cardiovascular and Lifestyle Risk Factors in Prostate Cancer Patients
RADICAL PC1 is a prospective cohort study of men with a new diagnosis of prostate cancer. RADICAL PC2 is a randomized, controlled trial of a systematic approach to modifying cardiovascular and lifestyle risk factors in men with a…
- Trial name
- RADICALPC (NCT03127631)
- Testing
- Nutrition, Exercise, Smoking cessation
- Where
- 61 sites in United States, Australia and 7 more
- Volunteers
- 5,000 people
- Sponsor
- McMaster University
Abdominal Obesity
Rosuvastatin in Visceral Adiposity
The purpose of this study is to investigate whether 6 months treatment with the cholesterol-lowering drug rosuvastatin may reduce visceral fat tissue in obese middle aged men.
- Trial name
- RIVIERA (NCT01068626)
- Testing
- Rosuvastatin
- Where
- Sweden
- Volunteers
- 54 people
- Sponsor
- Göteborg University
Hypercholesterolemia
Rosuvastatin ORBITAL Germany
The primary objective of the study is to compare the effect of rosuvastatin therapy plus compliance initiatives and rosuvastatin therapy alone for 12 months (52 weeks) on long-term cumulative direct and indirect disease-related…
- Trial name
- NCT00379249
- Testing
- Rosuvastatin
- Volunteers
- 8,000 people
- Sponsor
- AstraZeneca
Healthy
A Study of Lanabecestat (LY3314814) in Healthy Participants When Taken With Rosuvastatin
The purpose of this study is to evaluate the effect of lanabecestat on rosuvastatin. The amount of rosuvastatin in the blood will be compared, when taken alone, and then when taken with lanabecestat.
- Trial name
- NCT03019549
- Testing
- Lanabecestat, Rosuvastatin
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Dyslipidemias
Statin Monotherapy and Rosuzet Tab.(Rosuvastatin/Ezetimibe) Administration in Patients With Dyslipidemia in Korea
A Cohort Study for Comparison of Statin Monotherapy and Rosuzet Tab.(Rosuvastatin/Ezetimibe) Administration and Statin Prescription Patterns in Patients With Dyslipidemia in Korea.
- Trial name
- NCT04829149
- Testing
- Observational
- Where
- South Korea
- Volunteers
- 5,717 people
- Sponsor
- Hanmi Pharmaceutical Company Limited
Dyslipidemia, Long-Distance Running
The Effects of Rosuvastatin on Running Training Adaptation and Safety
Statins lower low-density lipoprotein cholesterol (LDL-C) and help prevent atherosclerotic cardiovascular disease, but some users develop statin-associated muscle symptoms (SAMS) such as soreness, stiffness, weakness, or elevated…
- Conditions
- Dyslipidemia, Long-Distance Running, Endurance Training, Statin-Associated Muscle Symptoms
- Trial name
- NCT07401017
- Testing
- Rosuvastatin
- Where
- Taiwan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University WanFang Hospital
Atherosclerosis Cerebral, Carotid Plaque
RESCUE: PCSK9 Inhibitors for Carotid Vulnerable Plaque Remodeling
Carotid artery stenosis is a major cause of ischemic stroke. However, many strokes occur in patients with only mild-to-moderate stenosis.
- Conditions
- Atherosclerosis Cerebral, Carotid Plaque, Vulnerable Plaque, Carotid Stenosis
- Trial name
- RESCUE (NCT07819643)
- Testing
- Intervention 1, Intervention 3, Intervention 2
- Volunteers
- 120 people
- Sponsor
- Keqiang Zhao
Coronary Artery Disease
Polygenic Risk-based Detection of Subclinical Coronary Atherosclerosis and Intervention With Statin and Colchicine
The goal of this double-blind randomized controlled trial is to determine how treatment with high intensity statin, low-dose colchicine, and their combination modulates progression and composition of coronary atherosclerosis in…
- Trial name
- PROACT 2 (NCT05850091)
- Testing
- Rosuvastatin, Colchicine
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Massachusetts General Hospital
Paroxysmal Atrial Fibrillation
Study of Statin for Reduction of Postoperative Paroxysmal Atrial Fibrillation
The study will select all recruited patients with paroxysmal atrial fibrillation will be randomly allocated to receive oral rosuvastatin 20mg/day or blank control from 7 days before ablation and last for 3 months.
- Trial name
- NCT02502110
- Testing
- rosuvastatin
- Volunteers
- 346 people
- Sponsor
- The Third Xiangya Hospital of Central South University
Coronary Artery Disease, Hyperlipidemia
Evaluation of Statin-induced Lipid-rich Plaque Progression by Optical Coherence Tomography (OCT) Combined With Intravascular Ultrasound (IVUS)
Many trials suggested that lipid lowering therapy could significantly reduce cardiovascular events. Enhancing stability of vulnerable plaque is probably the main reason by which statins reduce adverse coronary events.
- Trial name
- NCT01023607
- Testing
- Atorvastatin, Rosuvastatin
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Harbin Medical University