Clinical trials: Routine care
Infection, Cancer
TTV-based mAnagement Of Long-term ImmunosuppreSsion in Kidney Transplantation
Long-term outcomes in kidney transplantation remain a significant challenge, as complications such as donor-specific antibodies (DSA), antibody-mediated rejection, infections, and cancer increasingly threaten graft and patient…
- Conditions
- Infection, Cancer, Rejection, Kidney Transplantation
- Trial name
- TAOIST (NCT06829719)
- Testing
- TTV DNAemia, EQ-5D-5L questionnaire, Biological tests
- Where
- 4 sites in France
- Volunteers
- 600 people
- Sponsor
- Hospices Civils de Lyon
Delirium
Fecal Microbiota Transplantation for the Treatment of ICU Delirium
Delirium in the intensive care unit (ICU) is a prevalent and serious neurological complication among critically ill patients, with large multicenter studies reporting an incidence of 30% to 80%, particularly in those requiring…
- Trial name
- FMTID (NCT07348471)
- Testing
- Intestinal microbiota suspension
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Stunting, Anemia
Effectiveness Study During the First 1,000 Days in Kenya
Malnutrition is a public health problem in Kenya, with 26% of children underfive years of age stunted, and 26% of pre-school children, 26% of women of reproductive age and 42% of pregnant women being anaemic, respectively.
- Conditions
- Stunting, Anemia, Micronutrient Deficiency
- Trial name
- NCT03558464
- Testing
- Intervention (integrated package), Control
- Where
- Kenya
- Volunteers
- 1,199 people, healthy volunteers welcome
- Sponsor
- Fabian Rohner
Acute Otitis Media (AOM), Strep Pharyngitis
Evaluation of the Medentum Diagnostik Platform for Pediatric ENT Conditions and Asthma
This study evaluates the diagnostic performance, usability, and clinical utility of the Medentum Diagnostik platform, a multisensor device with integrated software and artificial intelligence, in pediatric patients with asthma…
- Conditions
- Acute Otitis Media (AOM), Strep Pharyngitis, Asthma Exacerbation, Pediatric Asthma
- Trial name
- NCT07500532
- Testing
- Diagnostik home-based platform: multisensor device, software application, and artificial-intelligence algorithms that predict diagnosis of AOM and strep pharyngitis, Diagnostik home-based platform: multisensor device, software application, and artificial-intelligence algorithms that predict diagnosis of wheeze/asthma exacerbation, Routine Asthma Management (in-person and telehealth visits)- Control Group
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Medentum Innovations
Hypercholesterolemia, Medication Adherence
Effectiveness of a Combined Strategy to Improve Therapeutic Compliance and Degree of Control Among Patients With Hypercholesterolaemia
Background In subjects with hypercholesterolaemia, cholesterol values remain above guideline levels. One of the limiting factors to the achievement of goals in such patients is therapeutic non-adherence.
- Conditions
- Hypercholesterolemia, Medication Adherence, Primary Health Care
- Trial name
- EFESCOM (NCT02314663)
- Testing
- "COMBINED STRATEGY"
- Volunteers
- 358 people
- Sponsor
- Gerencia de Atención Primaria, Albacete
Precapillary Pulmonary Hypertension, Pulmonary Arterial Hypertension
Evolution of Hypoxic Burden and Sympathetic/Parasympathetic Balance in Patients With Pulmonary Hypertension
Background and Rationale: Sleep-disordered breathing and nocturnal hypoxemia are highly prevalent in patients with precapillary pulmonary hypertension (PH), and current guidelines recommend systematic sleep assessment in this…
- Conditions
- Precapillary Pulmonary Hypertension, Pulmonary Arterial Hypertension, Sleep-disordered Breathing, Nocturnal Hypoxemia
- Trial name
- HRV&PH (NCT07464184)
- Testing
- Standard Clinical and Functional Assessment, Overnight Polysomnography
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Rouen
COVID-19, Respiratory Tract Infections
Tobacco Use and the Risk of COVID-19 and Adverse Outcomes
This is an observational study of pooled population-based samples in three Nordic countries. Country-specific data has already been analysed in previous studies in Sweden, Finland, and Norway.
- Conditions
- COVID-19, Respiratory Tract Infections, Infections, Pneumonia, Viral
- Trial name
- NCT05321433
- Where
- Sweden
- Volunteers
- 757,585 people
- Sponsor
- Karolinska Institutet
Breast Cancer, Breast Cancer and Rehabilitation
Tai-Chi Exercise Reduces Fatigue in Breast Cancer Patients Undergoing Chemotherapy
Tai-Chi Exercise Reduces Fatigue in Breast Cancer Patients Undergoing Chemotherapy. The main question it aims to answer is: Does Tai-chi training reduce fatigue in breast cancer patients? Participants performed the exercise on…
- Trial name
- NCT07702409
- Testing
- Tai-chi, Daily Physical Activities
- Where
- Indonesia
- Volunteers
- 61 people
- Sponsor
- Chairul Huda
Taste Disorders, Breast Cancer
Incidence of Dysgeusia in Breast Cancer Patients Undergoing Chemotherapy
The goal of this observational study is to examine how frequently changes in taste occur in people with early-stage breast cancer who receive chemotherapy.
- Conditions
- Taste Disorders, Breast Cancer, Quality of Life, Taste Perception
- Trial name
- GustiAmo (NCT07317752)
- Testing
- Taste Assessment / Nutritional Assessment / Quality of Life Assessment
- Volunteers
- 40 people
- Sponsor
- Azienda Sanitaria Locale CN2 Alba-Bra
Growth Hormone Deficiency
Effects of Growth Hormone (GH) Deficiency and Growth Hormone Replacement on Serum Fibroblast Growth Factor 21 (FGF21)
This study will recruit healthy controls (who have normal GH production and growth hormone levels) and patients identified as having GHD, who are deemed eligible for GH replacement therapy according to NICE guidelines.
- Trial name
- NCT02243852
- Testing
- Growth Hormone Replacement Therapy
- Where
- 2 sites in United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Liverpool
Oral Cancer, Reconstructive Surgery
App-Assisted Swallowing Program After Oral Cancer Surgery
This study aims to examine the effects of a swallowing care program combined with an exercise mobile application (App) on swallowing function, anxiety, and quality of life in patients with oral cancer after flap reconstruction…
- Conditions
- Oral Cancer, Reconstructive Surgery, Postoperative
- Trial name
- AASP (NCT07301047)
- Testing
- Swallowing Care + Exercise App, Routine Postoperative Care
- Where
- Taiwan
- Volunteers
- 72 people
- Sponsor
- Chang Gung Memorial Hospital
Acute Kidney Injury
Preconditioning Against Renal Damage Under Contrast Examination
This study aims to assess if applying an ischaemic insult to an arm before giving intravenous contrast will help decrease the incidence of developing contrast induced acute renal injury in patients undergoing contrast-enhanced CT…
- Trial name
- Re-DUCE-F (NCT02054858)
- Testing
- RIPC
- Where
- Ireland
- Volunteers
- 1,000 people
- Sponsor
- Mid Western Regional Hospital, Ireland
Pressure Injury
Evaluating an Intelligent Module for Pressure Injury Nursing Management
This is a study conducted in a hospital to evaluate whether applying an intelligent information technology can help nurses better prevent and manage bedsores (also known as pressure injuries) in hospitalized patients.
- Trial name
- IM-PINM (NCT07208747)
- Where
- China
- Volunteers
- 75,263 people
- Sponsor
- Xiamen Humanity Hospital
Maternal and Child Health, Maternal Nutrition
Social Networks for Improving Maternal & Child Health
Brief Summary: Improving Maternal and Child Health via Indigenous Structures The goal of this cluster randomized controlled community trial is to assess the effect of community-based interventions using indigenous community…
- Trial name
- SoNIMCH (NCT07522047)
- Testing
- Community-based Health and Nutrition Counseling via Indigenous Social Support Structures (ISSS)
- Where
- Ethiopia
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Bahir Dar University
EGD Procedure
Case Series With Saneso 360° Gastroscope
To confirm the procedural performance of the Saneso 360° gastroscope in Esophago-gastro-duodenoscopy (EGD) procedures.
- Trial name
- NCT04621591
- Testing
- Saneso 360° gastroscope
- Where
- 6 sites in United States
- Volunteers
- 22 people
- Sponsor
- Saneso Inc.
Rotator Cuff-related Shoulder Pain, Shoulder Pain
Personalised Education Versus Usual Physiotherapy for Acute Rotator Cuff-Related Shoulder Pain
Rotator cuff-related shoulder pain (RCRSP) is one of the most common musculoskeletal disorders presenting in primary care. It is frequently associated with persistent pain, disability, healthcare utilisation and work absenteeism.
- Conditions
- Rotator Cuff-related Shoulder Pain, Shoulder Pain, Shoulder Disability
- Trial name
- SHOULD-ER (NCT07859891)
- Testing
- Personalised, Multimodal Educational Intervention, Usual Physiotherapy Care
- Where
- France
- Volunteers
- 118 people
- Sponsor
- Centre Hospitalier Régional d'Orléans
Breastfeeding, Attachment
Promoting Mother-baby Bonding Through Sustainable Breastfeeding Practices
This research aimed to identify sustainable breastfeeding practices and green mothers' initiatives to develop a strong mother-child bond.
- Trial name
- NCT06781190
- Testing
- Green motherhood education
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Safety and Effectiveness of Midline Catheters, Vascular Access Devices
Evaluating Midline Catheters in Clinical Practice
The goal of this observational study is to learn about the safety and effectiveness of midline catheters in patients who receive midline catheter placement as part of their routine clinical care.
- Trial name
- NCT07677696
- Testing
- Midline catheter placement
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Shandong Branden Med.Device Co.,Ltd
Colorectal Cancer
Improving 5-Fluorouracil (5-FU) Continuous Infusion Comfort With a New Corset Design in People Affected by Cancer
This feasibility randomized controlled trial aims to evaluate the effectiveness and usability of a newly designed supportive corset for patients receiving continuous 5-Fluorouracil (5-FU) infusion therapy.
- Trial name
- RCT (NCT07317583)
- Testing
- Supportive Corset, Standard care
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Istanbul University - Cerrahpasa
Obesity & Overweight, Diabetes Mellitus Type 2
Pre-Diagnosis GLP-1 Receptor Agonist Use and Post-Cancer Mortality in Adults With Obesity and Type 2 Diabetes
This study will examine whether the type of diabetes treatment used before cancer diagnosis is associated with survival and serious complications after obesity-associated cancer in adults with obesity and type 2 diabetes.
- Conditions
- Obesity & Overweight, Diabetes Mellitus Type 2, Neoplasms
- Trial name
- NCT07513259
- Where
- Taiwan
- Volunteers
- 203,424 people
- Sponsor
- Chung Shan Medical University
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