Clinical trials: Routine care
Brain Abscess
MICROBIOLOGY OF CEREBRAL ABSCESSES
Establish the repertoire of bacteria and Archaea responsible for brain abscesses. Correlate the microbial repertoire to epidemiological, clinical and radiological data; to define the different nosological entities falling within…
- Trial name
- NCT04018742
- Testing
- Surgical puncture
- Volunteers
- 20 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Neonatal Adaptation
Effect of Immediate Skin-to-Skin Contact on Neonatal Heart Rate Variability After Cesarean Secton
At birth, both the newborn and the mother experience adaptive stress, which can be measured using objective physiological methods.
- Trial name
- HRV-SCENE (NCT07109076)
- Testing
- skin-to-skin contact, routine care
- Where
- Slovenia
- Volunteers
- 80 people
- Sponsor
- University Medical Centre Ljubljana
Cirrhosis, Liver
Cirrhosis Care Alberta (CCAB): A Pragmatic Type II Hybrid Effectiveness Implementation Trial
Liver cirrhosis is the leading cause of morbidity and premature mortality in patients with digestive disease. There are many gaps in care which contribute to a high rate of hospital readmissions (44 percent at 90 days) and…
- Trial name
- CCAB (NCT04149223)
- Testing
- Evidence-based standardized Cirrhosis order set
- Where
- Canada
- Volunteers
- 3,975 people
- Sponsor
- University of Alberta
Tibial Shaft Fractures
Comparison of Functional Recovery Following Medial Parapatellar and Transpatellar Approaches for Intramedullary Nailing of Tibial Shaft Fractures
Tibial shaft fractures are breaks in the main part of the shin bone and commonly require surgery to restore alignment and allow the patient to return to normal activities.
- Trial name
- MAPTIN (NCT07761780)
- Testing
- Intramedullary Nailing Using Medial Parapatellar Approach, Intramedullary Nailing Using Transpatellar Approach
- Where
- Pakistan
- Volunteers
- 56 people
- Sponsor
- Allama Iqbal Medical College
Carpal Tunnel Syndrome (CTS), Carpal Tunnel Surgery
Evaluation by Clinical and Hand Ultrasound in Carpal Tunnel Syndrome
Carpal Tunnel Syndrome (CTS) is a common condition where pressure on the median nerve in the wrist causes pain, numbness, and weakness in the hand.
- Trial name
- ECHO-CTS (NCT07134361)
- Testing
- Open Carpal Tunnel Release
- Where
- Brazil
- Volunteers
- 106 people
- Sponsor
- University of Sao Paulo General Hospital
Exutbation Failure, Mechanical Ventilation
Ultrasonography for Prediction of Extubation Success: a Holistic Approach
This study evaluates thickening fraction alone and together with other ultrasound parameters of heart and lungs as predictors for extubation outcome
- Trial name
- APEX (NCT04196361)
- Testing
- Ultrasound
- Volunteers
- 83 people
- Sponsor
- Amsterdam UMC, location VUmc
Hypoxic Ischemic Encephalopathy of Newborn, Neonatal Encephalopathy
Investigating Cerebral Oxygenation in the Newborn
The goal of this single centre observational study is to use near-infrared spectroscopy (NIRS) monitoring to investigate cerebral oxygenation in two groups of newborn infants who are at high risk of brain injury.
- Conditions
- Hypoxic Ischemic Encephalopathy of Newborn, Neonatal Encephalopathy, Premature Infant Disease
- Trial name
- ICON (NCT05588960)
- Testing
- Near-infrared spectroscopy monitoring (Masimo O3 Regional Oximeter with Neonatal Sensor)
- Where
- United Kingdom
- Volunteers
- 99 people
- Sponsor
- University of Edinburgh
Dental Fear, Anesthesia, Local
Effectiveness of Synapse Transcutaneous Electronic Nerve Stimulation (TENS) During Dental Procedures Among Children
Dental Fear and Anxiety (DFA) are at higher levels among children and often leads to avoidance of dental treatment. Negative experiences in the early years such as experience of pain during injections, fillings, or extractions…
- Conditions
- Dental Fear, Anesthesia, Local, Pediatric Dentistry
- Trial name
- NCT03779659
- Testing
- Synapse TENS device, Topical anesthetic gel
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Boston University
Postpartum Depression, Psychoeducation
Psychoeducational Intervention to Reduce Depressive Symptoms and Strengthen Mother-Infant Bonding
The study aims to evaluate the effectiveness of a psychoeducational intervention designed within the framework of the Watson Human Caring Model in reducing postpartum depressive symptoms and creating a stronger mother-infant…
- Conditions
- Postpartum Depression, Psychoeducation, Mother-Infant Interaction
- Trial name
- NCT07062159
- Testing
- the psychoeducation intervention program, routine care
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Yasemin Ozhuner
SARS-CoV 2, Viral Infection
Anti-SARS Cov-2 T Cell Infusions for COVID 19
This is a dose-finding safety trial followed by a randomized pilot trial comparing administration of SARS-CoV2-specific T cells (SARS-CoVSTs) to standard of care treatment in hospitalized patients with COVID19 who are at high…
- Conditions
- SARS-CoV 2, Viral Infection, COVID 19
- Trial name
- BATIT (NCT04401410)
- Testing
- Dose Finding Phase (MTD), Partially HLA-matched SARS-CoVSTs, Routine care (no SARS-CoVSTs)
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Baylor College of Medicine
SARS-CoV 2, COVID-19
Favipiravir vs Hydroxychloroquine vs Control in COVID -19
Hydroxychloroquine is widely used to treat autoimmune diseases. Clinical investigation has found that a high concentration of cytokines were detected in the plasma of critically ill patients infected with SARS-CoV-2, therefore…
- Trial name
- NCT04387760
- Testing
- Hydroxychloroquine, Favipiravir, Routine care for COVID-19 patients
- Where
- Bahrain
- Volunteers
- 150 people
- Sponsor
- Royal College of Surgeons in Ireland - Medical University of Bahrain
Labor and Delivery, Labor Comfort
Effect of Mechanical Massage Cushion on Labor Pain and Comfort
This study was conducted to examine the effect of mechanical massage applied with a mechanical massage cushion during labor on labor pain and comfort. This research is a randomized controlled experimental study.
- Conditions
- Labor and Delivery, Labor Comfort, Labor Pain, Pregnant Women
- Trial name
- NCT07566962
- Testing
- massage
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Tarsus University
Placenta Previa Total, Nursing Role
Effects of Peri Partum Integrated Nursing Care Versus Routine Care in Placenta Previa : A Randomized Controlled Trail
At our institution, the annual number of placenta previa was 494 cases (1.7%); of whom 95 cases (19.2%) were proved to have a placenta accreta.
- Trial name
- NCT04274062
- Testing
- Integrated Nursing care of placenta previa
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Woman's Health University Hospital, Egypt
Breast Feeding, Exclusive
Evaluation of a Health Mediation Program in the Maternity Ward.
The first months of life are considered a critical period that has a lasting impact on a child's future health. Breastfeeding is one of the fundamental factors contributing to healthy growth in children.
- Trial name
- MédiMAT (NCT07806942)
- Testing
- postpartum breastfeeding support from a health mediator, routine health care without health mediation
- Where
- French Guiana
- Volunteers
- 960 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier de Cayenne
COVID-19 Pandemic, Vulnerable Subjects
Perceived Impact of the COVID-19 Pandemic on Medical Management and Symptoms in a High Risk Group
The Swiss population underwent a period of confinement related to the COVID-19 pandemic (March 16 to May 11, 2020) decided by the Swiss Federal Government.
- Conditions
- COVID-19 Pandemic, Vulnerable Subjects, Long-term Non-invasive Ventilation
- Trial name
- NCT04477473
- Testing
- Questionnaire-based observational study
- Where
- Switzerland
- Volunteers
- 66 people
- Sponsor
- University Hospital, Geneva
Lung Cancer
ERAS Compliance and Nutritional Outcomes After Lung Cancer Surgery
This prospective observational study will evaluate the association between ERAS protocol compliance and postoperative nutritional outcomes in 120 patients undergoing lung cancer surgery.
- Trial name
- ERAS-NUTRI (NCT07785791)
- Testing
- Routine ERAS Perioperative Care
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Bursa City Hospital
Type 1 Diabetes, Type 2 Diabetes
Automated Insulin Delivery for Inpatients With Dysglycemia
This randomized controlled trial will test the efficacy and safety of automated insulin delivery (AID) in hospitalized patients with diabetes (type 1 or type 2) requiring insulin therapy who are admitted to general…
- Trial name
- AIDING (NCT06418880)
- Testing
- AID system with Remote Real-Time CGM, Standard of Care Insulin Therapy + CGM
- Where
- 3 sites in United States
- Volunteers
- 130 people
- Sponsor
- Emory University
Venous Thromboembolism
Safety of Fondaparinux as Routine VTE Prophylaxis in Medical ICU Patients
This is a pilot study to evaluate safety of fondaparinux and enoxaparin in terms of bleeding and development of thrombocytopenia in the medical ICU population.
- Trial name
- NCT00493896
- Testing
- Fondaparinux, Enoxaparin
- Volunteers
- 27 people
- Sponsor
- Eastern Virginia Medical School
CVD
e-Care for Heart Wellness
The e-Care for Heart Wellness study will look at ways to reduce a person's chances of getting heart disease. We are asking about 100 Group Health members whose electronic medical record shows they have uncontrolled high blood…
- Trial name
- e-Compare (NCT01077388)
- Testing
- Dietician electronic support
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Kaiser Permanente
Asthma
Environmental Mycobiota: In-depth Characterisation and Determinants Involved in Asthma Emission
The analysis of the exposome of severe asthmatic patients and its correlation with the response profile to biotherapies used in the treatment of severe asthma and/or the frequency of exacerbations, could make it possible to…
- Trial name
- MyCADO (NCT05789927)
- Testing
- Assessment of the microbial exposome
- Where
- 2 sites in France
- Volunteers
- 80 people
- Sponsor
- University Hospital, Bordeaux
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