Clinical trials: Routine care, completed
Knee Osteoarthritis, Arthroplasty, Replacement, Knee
Implementation of Indication Criteria for Total Knee Replacement in Osteoarthritis (Value-based TKR)
The aim of this trial is to investigate the effect of a medical decision aid (EKIT-Tool) on decision quality for knee arthroplasty.
- Trial name
- NCT04837053
- Testing
- Digital decision aid for physicians and patients, Routine care
- Where
- Germany
- Volunteers
- 1,092 people
- Sponsor
- Technische Universität Dresden
Migraine
Migraine Prevention With the Remote Electrical Neuromodulation (REN) Wearable: A Real-world Evidence Study
Preventive pharmacologic therapies for migraine aim to reduce attack frequency and duration and improve quality of life; however, their use, overall benefit and adherence are often limited.
- Trial name
- NCT07487701
- Testing
- Nerivio REN device
- Where
- United States
- Volunteers
- 332 people
- Sponsor
- Theranica
Venous Leg Ulcer
A Study to Evaluate the Safety and the Efficacy of EscharEx (EX-02 Formulation) in Debridement of Venous Leg Ulcers
This study is a multicenter, prospective, randomized, placebo controlled, adaptive design study performed to assess the safety and the efficacy of 5% EscharEx (EX-02) compared to Gel Vehicle (placebo) and non-surgical standard of…
- Trial name
- NCT03588130
- Testing
- EscharEx (5% EX-02 formulation), Gel Vehicle, Non-surgical standard of care (NSSOC)
- Where
- 22 sites in United States, Switzerland
- Volunteers
- 120 people
- Sponsor
- MediWound Ltd
Acute Respiratory Tract Infection, Urinary Tract Infections
Routine Antibiotic Prescription Monitoring in Primary Care Physicians: A Nationwide Trial
Antibiotic resistance is an increasingly serious problem in Switzerland which is associated with the exposure and overall uptake of antibiotics in a population.
- Trial name
- NCT03379194
- Testing
- Antibiotic stewardship program
- Where
- Switzerland
- Volunteers
- 3,426 people
- Sponsor
- University Hospital, Basel, Switzerland
Abdominal Aortic Aneurysm, Carotid Atherosclerosis
Preconditioning Shields Against Vascular Events in Surgery
Major vascular surgery involves operations to repair swollen blood vessels, clear debris from blocked arteries or bypass blocked blood vessels.
- Conditions
- Abdominal Aortic Aneurysm, Carotid Atherosclerosis, Critical Lower Limb Ischaemia
- Trial name
- SAVES (NCT01691911)
- Testing
- Remote preconditioning
- Where
- Ireland
- Volunteers
- 200 people
- Sponsor
- Mid Western Regional Hospital, Ireland
Mentally Ill Persons, Psychiatric Diagnosis
MOHO's Impact on Life Skills & QoL in Mentally Ill Offenders: A Tamil Nadu Study
What is the goal of this study? The goal of this study is to learn if a 12-week occupational therapy programme based on the Model of Human Occupation (MOHO) can improve life skills and quality of life in mentally ill offenders in…
- Conditions
- Mentally Ill Persons, Psychiatric Diagnosis, Occupational Therapy
- Trial name
- MOHO (NCT07677644)
- Testing
- Model of Human Occupation (MOHO)
- Where
- India
- Volunteers
- 12 people
- Sponsor
- Sri Ramachandra Institute of Higher Education and Research
Hepatitis C
Hepatitis C Diagnosis to Treatment Management
The objective of this study is to evaluate whether sending alerts to healthcare providers and clinic staff to identify patients with untreated hepatitis C infection can increase the uptake of hepatitis C treatment.
- Trial name
- NCT05725109
- Testing
- Hepatitis C Treatment Alerts in CHORUS™, Standard of Care
- Where
- United States
- Volunteers
- 1,063 people
- Sponsor
- Epividian
Breast Cancer, Physical Activity
Physical Activity Intervention to Reduce Functional Health Disparities Among Breast Cancer Survivors
The purpose of this research study is to determine whether a physical activity (exercise) program in the community will improve the functional and overall health status of older women with a history of breast cancer.
- Trial name
- NCT02763228
- Testing
- Aerobic Training - Fixed Schedule, Resistance Training - Fixed Schedule, Walking program
- Where
- 3 sites in United States
- Volunteers
- 218 people
- Sponsor
- Case Comprehensive Cancer Center
Penile Cancer, Melanoma
Validation of ICG-99mTc-nanoscan as Hybrid Tracer for Sentinel Node Biopsy
99mTc-nanocolloid, the world wide used hybrid tracer for dynamic sentinel node biopsy, has recently been replaced with 99mTc-nanoscan.
- Conditions
- Penile Cancer, Melanoma, Oral Cancer
- Trial name
- NANOSCAN (NCT06666634)
- Testing
- Sentinel node biopsy with either ICG-99mTc-nanoscan or 99mTc-nanoscan
- Where
- Netherlands
- Volunteers
- 29 people
- Sponsor
- The Netherlands Cancer Institute
Acute Porphyrias
Controlled Trial of Panhematin in Treatment of Acute Attacks of Porphyria
This study aims to provide high quality evidence for the effectiveness and safety of hemin (PanhematinTM , Recordati) for treatment of acute attacks of porphyria.
- Trial name
- NCT02180412
- Testing
- Panhematin, Glucose
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Healthcare Associated Infections, Methicillin Resistant Staphylococcus Aureus
Active Bathing to Eliminate Infection (ABATE Infection) Trial
The ABATE Infection Project is a cluster randomized trial of hospitals to compare two quality improvement strategies to reduce multi-drug resistant organisms and healthcare-associated infections in non-critical care units.
- Conditions
- Healthcare Associated Infections, Methicillin Resistant Staphylococcus Aureus, Multi Drug Resistant Organisms
- Trial name
- ABATE (NCT02063867)
- Testing
- Arm 2: Decolonization
- Where
- 52 sites in United States
- Volunteers
- 53 people
- Sponsor
- University of California, Irvine
Transitional Care Model, Coronary Heart Disease
Medication Adherence and Lipid Management in Patients With Coronary Heart Disease After Percutaneous Coronary Intervention: Application of the Transitional Care Model
Patients with coronary heart disease (CHD) require long-term medication and lifestyle modification following percutaneous coronary intervention (PCI).
- Conditions
- Transitional Care Model, Coronary Heart Disease, Medication Adherence, Self-efficacy
- Trial name
- NCT07346664
- Testing
- routine nursing care group, TCM intervention group
- Where
- China
- Volunteers
- 108 people
- Sponsor
- Qing Wang
Atrial Fibrillation, Overweight and Obesity
LOSE-AF: Can Weight Loss Help Patients With Atrial Fibrillation?
Background Atrial fibrillation (AF) affects over 1 million individuals in the UK and results in costs of over £450 million per year to the National Health Service (NHS).
- Trial name
- LOSE-AF (NCT03713775)
- Testing
- Meal Replacement Weight Loss Programme, Usual Care
- Where
- United Kingdom
- Volunteers
- 119 people
- Sponsor
- University of Oxford
Depression
Managing Cancer and Living Meaningfully (CALM): A Study to Evaluate the Effectiveness of a Psychological Intervention for Cancer Patients
The purpose of this study is to test the effectiveness of a brief manualized individual psychotherapy, called Managing Cancer and Living Meaningfully (CALM), to reduce distress and promote psychological well-being in patients…
- Trial name
- CALM (NCT01506492)
- Testing
- CALM
- Where
- Canada
- Volunteers
- 305 people
- Sponsor
- University Health Network, Toronto
Lower Limb Ischemia
Non-Interventional Post Marketing Surveillance Study of Neovasculgen® in Patients With Chronic Lower Limb Ischemia
Aim of the study is to gain more knowledge about efficacy and safety of Neovasculgen® in daily clinical practice and obtain information about the quality of life in patients treated with Neovasculgen®.
- Trial name
- NVG-LIGHT (NCT02369809)
- Testing
- Neovasculgen®
- Where
- 30 sites in Russia
- Volunteers
- 210 people
- Sponsor
- Artgen Biotech
Carcinoma, Non-Small-Cell Lung
Evaluate the Impact of Afatinib on Quality of Life and Symptom Burden of Greek Subjects With Advanced NSCLC in Routine Patient Care Settings
This non-interventional study will include a representative sample of patients with locally advanced or metastatic NSCLC harboring Epidermal Growth Factor Receptor (EGFR)-mutations in Greece.
- Trial name
- NCT02440854
- Testing
- afatinib
- Where
- 7 sites in Greece
- Volunteers
- 80 people
- Sponsor
- Boehringer Ingelheim
Endometrial Cancer
TREC Lifestyle Beyond Cancer Study in Endometrial Cancer Survivors
This randomized, controlled study evaluates the efficacy of weigh loss interventions in endometrial cancer survivors, using novel technology-based weight loss platforms.
- Trial name
- NCT02466061
- Testing
- Telemedicine Weight Management plus Wi-Fi Scale (Arm A), Text for Diet (Text4Diet) Group (Arm B), Enhanced Usual Care Group (Arm C)
- Where
- 3 sites in United States
- Volunteers
- 207 people
- Sponsor
- Fred Hutchinson Cancer Center
Breastmilk, Oral Care
Oral Care With Breast Milk in Preterm Newborns Fed by Tube
It was conducted to evaluate Oral Care with Breast Milk in Preterm Newborns Fed by Tube
- Trial name
- NCT06129266
- Testing
- oral care with breastmilk
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Karabuk University
Trachoma
Enhancing the A in SAFE for Trachoma
This study will assess the cost and feasibility of two strategies of enhanced Mass Drug Administration (MDA) of Zithromax to treat trachoma in the Republic of South Sudan.
- Trial name
- NCT05634759
- Testing
- Azithromycin for Routine Community-wide MDA, Two Additional Rounds of Azithromycin for Children, Azithromycin for Second Community-wide MDA
- Where
- South Sudan
- Volunteers
- 34,630 people, healthy volunteers welcome
- Sponsor
- Emory University
Pneumonia, Mechanical Ventilation Complication
Oral Care of Intubated Intensive Care Patient
The aim of the research was to examine the effect of oral care bundle application on oral health, salivary pH (power of hydrogen), dry mouth and ventilator associated pneumonia in intubated patients compared to standard oral care.
- Conditions
- Pneumonia, Mechanical Ventilation Complication, Salivation, Dry Mouth
- Trial name
- NCT06258603
- Testing
- oral care bundle, clinical oral care
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Nigde Omer Halisdemir University
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