Clinical trials: Routine care
Substance Abuse Disorder
Evaluating Three Methods for Helping Syringe Exchangers Begin Methadone Maintenance
This research is being done to evaluate the effectiveness of three different treatment strategies for helping subjects begin and adjust to methadone maintenance treatment at Addiction Treatment Services (ATS).
- Trial name
- NCT01142986
- Testing
- Low intensity care, Voucher reinforcement
- Where
- United States
- Volunteers
- 223 people
- Sponsor
- Johns Hopkins University
Scoliosis Patients
Feasibility, Acceptability, and Preliminary Effects of Virtual Reality for Pain, Anxiety and Recovery Enhancement of Children Post-scoliosis Surgical Repair
Adolescent idiopathic scoliosis is the most common spinal deformity in adolescents and frequently requires surgical intervention when curvature becomes severe.
- Trial name
- VR-SPINE (NCT07737886)
- Testing
- Virtual Reality, Standard medical treatment
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- St. Justine's Hospital
Ocular Infection, Viral
Can COVID-19 Persist in Intraocular Fluid?
Several common viruses thrive and persist in intraocular fluid due to ocular immune privilege. Immune privilege is maintained by lack of lymphatic tissue, a strong blood ocular barrier, and regulation of the systemic immune…
- Trial name
- NCT04945850
- Testing
- routine care intraocular sx
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Pain, Chronic
Post Discharge Online Telerehabilitation Program
This study will evaluate the sustainability of pain and functional outcomes along with return to opioid use in a population of patients that successfully completed a comprehensive interdisciplinary pain rehabilitation program.
- Trial name
- OTP (NCT03480620)
- Testing
- Online Telerehabilitation Platform Access, Usual care
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Brooks Rehabilitation
Coronary Computed Tomography Angiography, Contrast Media
Optimization of Patient Preparation and Imaging Techniques for Cardiac CT
The goal of this clinical trial is to compare four different methods of reducing heart rate before cardiac imaging. The diagnostic imaging technique used in this study is called Computed Tomography (CT) of the coronary vessels…
- Conditions
- Coronary Computed Tomography Angiography, Contrast Media, Cardiac Output
- Trial name
- NCT06879769
- Testing
- Metoprolol I.V., Metoprolol I.V. and 1 hour waiting., Music Intervention, Seloken (Recordati) orally and Metoprolol I.V.
- Where
- Sweden
- Volunteers
- 240 people
- Sponsor
- Karolinska University Hospital
Central Nervous System Diseases
Combined Analysis of Inflammatory Biomarkers for CNS Autoimmune Diseases Diagnostic
Project rationale: Since 2017, multiple sclerosis diagnosis should match the new McDonald criteria in which a "no better explanation than MS" should be fulfilled.
- Trial name
- CyBIRD (NCT05056740)
- Testing
- Data analysis
- Where
- France
- Volunteers
- 300 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Pediatrics, Lobar Pneumonia
Application and Effect Evaluation of Integrated Nursing and Medical Management in Pediatric Lobar Pneumonia
Integrated nursing and medical management significantly improves clinical symptoms and pulmonary function in children with lobar pneumonia, shortens hospitalization duration, reduces complication rates, and enhances caregiver…
- Conditions
- Pediatrics, Lobar Pneumonia, Inflammatory Markers, Satisfaction
- Trial name
- NCT06945991
- Testing
- observation group, control group
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Children's Hospital of Hebei Province
Breast Cancer, Nausea and Vomiting
The Impact of Oral Cryotherapy and Chewing Gum Interventions
Chemotherapy-induced nausea and vomiting (CINV) and taste alterations continue to be among the most common and most severe side effects that women receiving adjuvant chemotherapy for breast cancer suffer.
- Conditions
- Breast Cancer, Nausea and Vomiting, Quality of Life, Chewing Gum
- Trial name
- NCT07145320
- Testing
- Oral Cryotherapy Group (Group 1), Chewing Gum Group (Group 2)
- Where
- Turkey (Türkiye)
- Volunteers
- 135 people
- Sponsor
- Hacettepe University
Osteoarthritis
The Use of Compression Bandages in Total Knee Replacement Surgery
The use of compression bandages in elective orthopaedic knee surgery is well regarded, however, there is a lack of robust, well-designed evidence to support this.
- Trial name
- NCT02253680
- Testing
- Actico, short-stretch, inelastic dressing
- Where
- 2 sites in United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Northumbria Healthcare NHS Foundation Trust
Cancer
Blue-Button Regional Trial Screening
Enrollment in clinical trials predicts better survival in the most common cancer types including breast cancer, and testing and proving the efficacy of new treatments relies on successfully conducting clinical trials.
- Trial name
- NCT05885880
- Testing
- Blue-button screening
- Where
- 2 sites in United States
- Volunteers
- 600 people
- Sponsor
- American Cancer Society Cancer Action Network
Motivational Interviewing, Stress
Motivational Interviewing Applied to Individuals With Diabetes
This study will be conducted using a randomized controlled trial design to evaluate the effect of online individual motivational interviewing on well-being, stress and difficulties in individuals with diabetes.
- Conditions
- Motivational Interviewing, Stress, Well-Being, Psychological, Diabetes Mellitus
- Trial name
- NCT06345196
- Testing
- motivational interview
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Bozok University
Multiple Sclerosis, Relapsing-Remitting
Cellular microRNA Signatures in Multiple Sclerosis
A limited number of studies on microRNA expression variation in immune cells have been reported in relapsing-remitting multiple sclerosis (RRMS).
- Trial name
- SEP-MIR (NCT05290688)
- Testing
- 50 ml blodd sampling
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Institut Pasteur
Pain
Effects and Dose Response of Dexamethasone on Intercostal Blocks With Bupivicaine in Post Thoracic Surgery Patients
Post-op analgesia is the most important part of early and safe patient recovery in thoracic surgery. This is for both humane and patient outcome reasons.
- Trial name
- NCT02936427
- Testing
- Dexamethasone
- Where
- Ireland
- Volunteers
- 60 people
- Sponsor
- University College Dublin
Lactation Disorder With Baby Delivered, Nutrition Disorder, Infant
Macronutrients in Lactating NICU Parents - Impact of Kangaroo Care
The goal of this clinical trial is to learn about the impact of Kangaroo Care (holding your baby skin-to-skin on your chest) in lactating parents with babies in the Neonatal Intensive Care Unit (NICU) that cannot directly…
- Trial name
- MILK (NCT06047470)
- Testing
- Kangaroo Care, No Kangaroo Care
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Aging, Institutionalized Older Adults
Effects of Exercise, Cognitive Training, and Their Combination in Institutionalized Older Adults
The goal of this clinical trial is to learn if physical exercise, cognitive stimulation, or a combination of both can improve mobility, cognitive function, and psychosocial well-being in institutionalized older adults aged 65 and…
- Conditions
- Aging, Institutionalized Older Adults, Cognitive Abilities, Mobility and Independence
- Trial name
- NCT07082504
- Testing
- Physical Exercise Program, Cognitive Stimulation Program, Combined Physical Exercise and Cognitive Stimulation
- Volunteers
- 140 people
- Sponsor
- University of Salamanca
Spinal Cord Injury, Pressure Injury
Telemedicine Makes the Patient Stay in Hospital at Home
The goal of the project is to study whether multidisciplinary follow- up performed via telemedicine to the patient in his or her own home, will improve the healthcare services offered to a particular group of patients.
- Trial name
- TeleSCIpi (NCT02800915)
- Testing
- Service innovation with focus on multidisciplinary collaboration
- Where
- Norway
- Volunteers
- 56 people
- Sponsor
- Sunnaas Rehabilitation Hospital
Hypertrophic Cardiomyopathy
A Retrospective Cohort Study of Mavacamten Patient Support Program in Canada
This real-world study will describe the demographic and clinical characteristics and mavacamten treatment of adult patients with obstructive hypertrophic cardiomyopathy who participated in the Bristol-Myers Squibb (BMS)-sponsored…
- Trial name
- NCT06549608
- Testing
- Mavacamten
- Where
- Canada
- Volunteers
- 683 people
- Sponsor
- Bristol-Myers Squibb
Cardiovascular Diseases (CVD), Preoperative Anxiety
Culturally Tailored Nurse-Led Holistic Spiritual Care Improves Hemodynamic Stability and Well-Being in Cardiac Surgery Patients
This study aims to evaluate the effectiveness of culturally tailored nurse-led holistic spiritual care in improving hemodynamic stability and psychological well-being among patients undergoing preoperative cardiac surgery in…
- Conditions
- Cardiovascular Diseases (CVD), Preoperative Anxiety, Cardiac Surgery
- Trial name
- CARE-Cardiac (NCT07540598)
- Testing
- Culturally Tailored Nurse-Led Holistic Spiritual Care
- Where
- Indonesia
- Volunteers
- 248 people
- Sponsor
- Lincoln University College Malaysia
Achalasia Cardia, GERD (Gastroesophageal Reflux Disease)
Biological Optimization Versus Standard Care in Post-POEM Achalasia Patients (BIO-POEM)
This study aims to evaluate whether a structured biological optimization program can improve reflux symptoms and overall recovery in patients with achalasia cardia who previously underwent Peroral Endoscopic Myotomy (POEM).
- Trial name
- BIO-POEM 1 (NCT07620899)
- Testing
- Structured Biological Optimization
- Where
- India
- Volunteers
- 166 people
- Sponsor
- Asian Institute of Gastroenterology, India
Urinary Tract Stones
Multicenter Study to Develop a Model to Identify Uric Acid Urinary Tract Stones Using CT and Lab Tests
Urinary tract stones are a common condition affecting the kidney, ureter, bladder, and urethra. Uric acid stones represent an important subtype of urinary stones and require different prevention and treatment strategies compared…
- Trial name
- UAS-Model (NCT07328932)
- Testing
- No intervention (observational study)
- Where
- China
- Volunteers
- 1,650 people
- Sponsor
- Jian Zhuo
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